{"title":"Eosinophilic gastrointestinal disorders: variations in eosinophilic counts among investigators and staining methods.","authors":"Mina Ikeda, Satoshi Arakawa, Takashi Kobayashi, Ken-Ichi Inada, Yuka Kiriyama, Takahiko Sakuma, Takuma Ishihara, Akiko Yagami, Kayoko Suzuki, Kyoko Futamura, Senju Hashimoto, Hironao Miyoshi, Satoshi Yamamoto, Haruhiko Tachino, Yoshihiro Imaeda, Hiroyuki Kato, Yukio Asano, Yoshiaki Katano, Akihiko Horiguchi","doi":"10.20407/fmj.2024-019","DOIUrl":"https://doi.org/10.20407/fmj.2024-019","url":null,"abstract":"<p><strong>Objective: </strong>Eosinophilic gastrointestinal disorders (EGIDs) are pathologically diagnosed by manually counting the eosinophils in biopsy tissue under microscopy. However, the skill of the individual examiner is considered to influence the accuracy of the resulting eosinophil count (EC). This study aimed to examine the effects of different examiners and histopathological staining types on the EC results of pathological tissues from patients with EGIDs.</p><p><strong>Methods: </strong>Infiltrating eosinophils in lesion tissues from 10 eosinophilic esophagitis and 28 eosinophilic gastroenteritis cases were counted by three pathologists and one cytotechnologist. The intra- and inter-observer variabilities in ECs related to hematoxylin-eosin (HE), May-Grünwald Giemsa (MG), and direct fast scarlet (DFS) staining were investigated. The effects of examiner expertise and staining method on ECs were analyzed using a linear mixed effects model. The difference in color value (ΔE) for each staining method was obtained using the Commission International de l'Eclairage luminance-a-b model (L*a*b*).</p><p><strong>Results: </strong>There was no significant intra-observer variability in eosinophil counting. Regarding inter-observer agreement, the examiner with the most EGIDs experience reported higher ECs than the other examiners for all three staining types (<i>P</i><0.001). ECs were significantly higher with MG and DFS staining than with HE staining, regardless of the examiner (both <i>P</i><0.001). Additionally, the ΔE values with DFS were higher than those with MG and HE.</p><p><strong>Conclusions: </strong>DFS staining offered the most selective visualization of eosinophils. ECs may vary depending on both the skill of the examiner and the staining method.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"11 2","pages":"70-77"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fujita Medical JournalPub Date : 2025-05-01Epub Date: 2024-12-27DOI: 10.20407/fmj.2024-023
Ayana Mawaki, Masushi Kohta, Aya Yoshimura, Toshio Nakatani, Shizuko Nagao, Junko Sugama
{"title":"Effect of docetaxel administration on fluid dynamics in mice.","authors":"Ayana Mawaki, Masushi Kohta, Aya Yoshimura, Toshio Nakatani, Shizuko Nagao, Junko Sugama","doi":"10.20407/fmj.2024-023","DOIUrl":"https://doi.org/10.20407/fmj.2024-023","url":null,"abstract":"<p><strong>Objectives: </strong>The taxane chemotherapeutic agent docetaxel has been used as a therapy for various cancers. Some patients receiving docetaxel develop serious problems with fluid retention, which leads to peripheral edema formation, reducing the patient's quality of life. This study investigated the effect of docetaxel administration on fluid dynamics in mice as a step toward developing advanced preventive measures in nursing.</p><p><strong>Methods: </strong>Mice were administered 10 mg/kg/day of docetaxel intravenously for 5 days as the intervention group or with normal saline as the control group. To investigate fluid dynamics on day 5, the leakage of blood plasma, interstitial fluid volume, and fluid transportation capacity into lymph vessels were evaluated and compared between the two groups.</p><p><strong>Results: </strong>The Miles assay with Evans Blue, an albumin-binding dye, revealed that leakage of blood plasma was significantly increased in the control group compared with the intervention group (p<0.01). Results of the interstitial fluid volume and fluid transportation capacity were similar between the two groups, but the fluid transportation capacity tended to be higher in the intervention group.</p><p><strong>Conclusions: </strong>Docetaxel administration in our mouse model caused the leakage of blood plasma without proteins from the blood vessels into the interstitial tissues, which appeared at the initial stage of edema formation. This model might be useful for assessing the leakage of blood plasma and, subsequently, the development of preventive measures against edema formation.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"11 2","pages":"59-63"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040483/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fujita Medical JournalPub Date : 2025-05-01Epub Date: 2024-12-27DOI: 10.20407/fmj.2024-025
Harumi Kato, Yumiko Miyoshi, Kimie Takehara
{"title":"Draft of the self-regulated learning scale items for learning nursing skills based on the cyclical phase model and evaluation of their content validity.","authors":"Harumi Kato, Yumiko Miyoshi, Kimie Takehara","doi":"10.20407/fmj.2024-025","DOIUrl":"https://doi.org/10.20407/fmj.2024-025","url":null,"abstract":"<p><strong>Objectives: </strong>Extant studies report that self-regulated learning affects academic achievement and performance. Therefore, this study aimed to prepare a draft of a self-regulated learning scale to evaluate nursing skills learning based on the cyclical phase model, and to determine its content validity.</p><p><strong>Methods: </strong>Nine nursing students were interviewed to create an item pool. Next, focus group interviews were held with 6 nursing faculty members and 10 nursing students to refine the item pool and complete the drafting of scale items. Scores on the item-level content validity index (I-CVI) were obtained using a questionnaire survey of 11 nursing faculty members. Subsequently, an expert meeting was held to discuss the results. This study was approved by our university's Research Ethics Review Committee.</p><p><strong>Results: </strong>From the initial 175-item pool, 216 draft items were selected. Of these, 134 items had I-CVI values of 0.78 or higher. After further evaluation in the expert panel meeting, the validity of 141 items (23 in the forethought phase, 99 in the performance phase, and 19 in the self-reflection phase) was finally confirmed.</p><p><strong>Conclusions: </strong>A draft of a self-regulated learning scale for nursing skills was created for nursing students, and the validity of its 141 items was confirmed.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"11 2","pages":"78-85"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144041924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fujita Medical JournalPub Date : 2025-05-01Epub Date: 2024-12-27DOI: 10.20407/fmj.2024-018
Risa Kayama, Shota Suzumura, Soichiro Koyama, Kazuya Takeda, Kenta Fujimura, Takuma Ii, Hirofumi Ota, Shigeo Tanabe, Hiroaki Sakurai, Yoshikiyo Kanada
{"title":"A cross-sectional study of self-esteem, psychological factors, and academic performance among occupational therapy students in Japan.","authors":"Risa Kayama, Shota Suzumura, Soichiro Koyama, Kazuya Takeda, Kenta Fujimura, Takuma Ii, Hirofumi Ota, Shigeo Tanabe, Hiroaki Sakurai, Yoshikiyo Kanada","doi":"10.20407/fmj.2024-018","DOIUrl":"https://doi.org/10.20407/fmj.2024-018","url":null,"abstract":"<p><strong>Objectives: </strong>With the recent progression of a super-aging society in Japan, demand for medical and welfare professionals has increased, and occupational therapists are in great demand. Academic performance is important for occupational therapy and rehabilitation students. The current study aimed to determine the influence of self-esteem and psychological factors on academic performance in Japanese occupational therapy students.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 60 first-year occupational therapy students (16 male and 44 female) at a private medical university in Japan in June 2022. The State-Trait Anxiety Inventory (STAI) and Beck Depression Inventory Second Edition (BDI-II) were used to assess anxiety and depression symptoms, respectively, and the Rosenberg Self-Esteem Scale (RSES) was used to assess self-esteem.</p><p><strong>Results: </strong>We identified several factors affecting the examination performance of Japanese occupational therapy students. Self-esteem was significantly associated with examination performance in anatomy 1 (p=0.02, β=0.40). RSES-J social work (p=0.07, β=0.31) and anatomy 2 (p=0.08, β=0.30), STAI-JYZ (p=0.09, β=0.38), and STAI-JYZ rehabilitation medicine (p=0.06, β=0.44), and BDI-II (p=0.08, β=-0.43) showed no significant effects but exhibited a trend toward an association.</p><p><strong>Conclusions: </strong>Understanding the role of psychological aspects and self-esteem is important for constructing systems to support first-year university students. Furthermore, the development of psychological aspects and self-esteem is essential for improving the academic performance of occupational therapy students, and it is crucial to establish educational programs and support systems.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"11 2","pages":"91-97"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between eveningness and depressive symptoms in daytime workers: A cross-sectional analysis of the Aichi Workers' Cohort Study.","authors":"Kazuhito Ishihara, Tsuyoshi Kitajima, Atsuhiko Ota, Hiroshi Yatsuya, Nakao Iwata","doi":"10.20407/fmj.2024-021","DOIUrl":"https://doi.org/10.20407/fmj.2024-021","url":null,"abstract":"<p><strong>Objectives: </strong>Eveningness (evening preference in chronotype) has been reported to be associated with a number of psychiatric problems. We examined a cross-sectional association between eveningness and depressive symptoms in daytime workers.</p><p><strong>Methods: </strong>The subjects were 4410 civil servants (71.7% male, aged 18-69 years [mean, 43.5 years]) with no history of depressive disorder who did not perform shift work, and for whom there were no missing data. The association between eveningness, determined using the reduced Morningness-Eveningness Questionnaire, and depressive symptoms, determined using the shorter form of the Central Epidemiological Studies Depression scale, was assessed with logistic regression analysis adjusted for potential confounding factors (gender, income, living alone, breakfast intake, coffee consumption, drinking habits, exercise, smoking, working hours, sleep duration, and difficulty falling asleep).</p><p><strong>Results: </strong>Of the subjects, 529 (12.0%) had eveningness, and 1408 (31.9%) reported depressive symptoms. Depressive symptoms were reported more frequently by those with eveningness than by those with other chronotypes (57.3% vs 28.5%). The association between eveningness and depression (gender- and age-adjusted odds ratio, 3.27; 95% confidence interval, 2.71-3.95) was significant after adjustment for the other confounding factors (odds ratio, 2.40; 95% confidence interval, 1.96-2.95).</p><p><strong>Conclusions: </strong>Our results suggest that eveningness is associated with depressive symptoms among day workers and that this association is independent of potential confounding factors. Further longitudinal studies are needed to examine the causal relationship.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"11 2","pages":"64-69"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040487/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144062480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical utility of right atrial strain to estimate pulmonary hypertension in comparison with right ventricular free wall longitudinal strain.","authors":"Shinji Jinno, Akira Yamada, Maho Kawashima, Hideo Izawa","doi":"10.20407/fmj.2024-022","DOIUrl":"https://doi.org/10.20407/fmj.2024-022","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to measure right atrial (RA) strain in the reservoir, conduit, and contraction phases and examine its clinical utility in detecting pulmonary hypertension (PH).</p><p><strong>Methods: </strong>One hundred and thirteen patients hospitalized in the intensive or coronary care units of our institution who underwent echocardiography and measurements of RA/right ventricular (RV) strain were retrospectively examined. RA strain was measured in the reservoir, conduit, and contraction phases of one cardiac cycle. PH was defined as peak tricuspid regurgitation velocity >2.8 m/s. Patients were grouped according to PH status (PH, no PH) and statistically compared. Logistic regression and receiver operating characteristic analyses were also performed.</p><p><strong>Results: </strong>Mean age was 71.1±15.4 years and 72 were men (63.7%). The PH and no PH groups comprised 40 and 73 patients, respectively. Among the RA strain parameters, RA strain in the conduit phase was significantly lower in the PH group (-8.1±4.2% vs. -17.4±7.7%; p<0.001). In the receiver operating characteristic analysis for PH, RA strain in the conduit phase had the highest area under the curve among the RA/RV strain parameters (area under the curve, 0.88; sensitivity, 92.5%; specificity, 71.2%; p<0.001).</p><p><strong>Conclusions: </strong>RA strain is an echocardiographic parameter that can detect PH and should be considered when RV strain parameters are not measurable.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"11 2","pages":"86-90"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Growth of rehabilitation students in first and second years: A text mining approach.","authors":"Yin Xu, Hirofumi Ota, Soichiro Koyama, Shigeo Tanabe, Kazuya Takeda, Shota Suzumura, Hiroaki Sakurai, Yoshikiyo Kanada","doi":"10.20407/fmj.2024-024","DOIUrl":"https://doi.org/10.20407/fmj.2024-024","url":null,"abstract":"<p><strong>Objectives: </strong>This research used text mining to determine the impact of curricular experiences in each year of study on the formation of professional identity among students aspiring to become physical therapists (PTs) and occupational therapists (OTs).</p><p><strong>Methods: </strong>This study included 210 students (126 PT and 84 OT) enrolled at a single rehabilitation university in Japan in 2020 and 2021. These participants completed an open-ended questionnaire on personal growth 6, 12, 18 and 24 months after enrollment. Text mining was used to extract frequently occurring nouns from descriptive text data at these four time points. A hierarchical cluster analysis was then performed to generate clusters. The number of students mentioning at least one noun in each cluster was counted, and the proportion of students in each cluster was compared across the four time periods using Cochran's Q test.</p><p><strong>Results: </strong>The 16 nouns that appeared more than 30 times in 1073 sentences were classified into four clusters: \"action plan for passing the credit certification examination\", \"communication skill\", \"medical knowledge\" and \"school life with clinical practice in mind\". The proportion of students belonging to the four clusters varied across periods. \"Action plan for passing the credit certification examination\" and \"communication skill\" differed significantly across periods (p<0.0001 and p=0.0008, respectively).</p><p><strong>Conclusions: </strong>The results reveal how students have grown in their curriculum. Their growth was transformative.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"11 2","pages":"98-104"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12040481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144043903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fujita Medical JournalPub Date : 2025-02-01Epub Date: 2024-10-31DOI: 10.20407/fmj.2023-019
Zaliha Omar, Yohei Otaka, Eiichi Saitoh
{"title":"Design and implementation of a community-based rehabilitation curriculum for training multidisciplinary rehabilitation teams to serve people aging with disabilities.","authors":"Zaliha Omar, Yohei Otaka, Eiichi Saitoh","doi":"10.20407/fmj.2023-019","DOIUrl":"10.20407/fmj.2023-019","url":null,"abstract":"<p><strong>Objectives: </strong>We aimed to design and implement a community-based rehabilitation (CBR) curriculum to promote community engagement by multidisciplinary teams.</p><p><strong>Methods: </strong>Participants in this prospective interventional study at a rehabilitation institution for people aging with disabilities included learners, the chief executive officer of the institution, program auditors, and community members. A customized CBR curriculum was developed using systems thinking design. Thirty-five learners were trained through 36 instructional contact hours and 60 hours of guided self-directed learning. Learners completed pre-training self-reported questionnaires regarding knowledge and experience of CBR. During training, learners were evaluated continuously through observation, assignments, self-reported feedback questionnaires, and CBR projects. The chief executive officer was interviewed during the study. The program auditors were interviewed and wrote reports on the curriculum and observations regarding the CBR projects. Learners reported on community participation in these projects.</p><p><strong>Results: </strong>Thirty-three of 35 learners completed the program, 31 (94%) of whom had no prior knowledge of CBR. Learners implemented nine community engagement CBR projects, in which 1,293 community members participated. The auditors commended the curriculum content and its positive impact on learners and the community. The chief executive officer implemented inclusive community engagement at work. A CBR curriculum was dynamically developed for multidisciplinary rehabilitation team training to promote community engagement.</p><p><strong>Conclusions: </strong>The custom-designed CBR curriculum enabled multidisciplinary teams to practice community engagement at work. Equipped with CBR knowledge and skills, teams engaged with multiple sectors of the community to enhance patients' rehabilitation potential and increase public awareness through the implemented projects.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"11 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11782937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Implementation of support meetings for patients undergoing outpatient chemotherapy by a multidisciplinary cancer team.","authors":"Miho Jinno, Misako Dai, Kaori Ito, Yosuke Ando, Seira Toyosato-Nishibe, Maki Akiyoshi, Sachie Noda, Hidezo Matsuda, Naho Tsujii, Miho Zennami, Masami Yamamura, Yoko Katagata, Akemi Ito, Aki Takai, Shigeki Yamada, Kenji Kawada, Junko Sugama, Keiko Mano","doi":"10.20407/fmj.2024-005","DOIUrl":"10.20407/fmj.2024-005","url":null,"abstract":"<p><strong>Background: </strong>Outpatient chemotherapy is a standard treatment for cancer. In nursing care for outpatients, it is important to enhance patients' self-efficacy. Vicarious experiences that can be gained through interactions with other patients with cancer can be useful for achieving this. While inpatients can gain vicarious experiences through their hospital stay, outpatients typically have fewer opportunities to do so.</p><p><strong>Aims: </strong>This report aimed to examine the results of implementation of support meetings for patients receiving outpatient chemotherapy.</p><p><strong>Methods: </strong>Starting in April 2019, support meetings were held once a month for outpatients on Thursdays from 14:00 to 16:00 in a hospital conference room. Medical professionals designed the programme of support meetings to allow patients to interact with each other and engage in vicarious experiences. At each meeting, satisfaction regarding the support meeting content was evaluated by self-administered questionnaire. Moreover, the nurse asked all participants to talk about their interactions, and recorded and extracted narratives about vicarious experiences.</p><p><strong>Findings: </strong>The 32 participants had a median age (interquartile range) of 63.5 years (55-70 years). There were 26 females (81.2%). The median satisfaction scores ranged from 2.9 to 4 for the content of each meeting. Patients talked about the value of learning from the experiences of other patients and the easing of loneliness.</p><p><strong>Conclusion: </strong>The results suggested that support meetings can provide vicarious experiences for patients receiving outpatient chemotherapy.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"11 1","pages":"44-47"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11782945/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case of kidney graft injury during cesarean section in a pancreas and kidney transplantation recipient.","authors":"Noriko Aida, Eiji Nishio, Takao Sekiya, Naohiro Aida, Taihei Ito, Takashi Kenmochi, Haruki Nishizawa","doi":"10.20407/fmj.2024-008","DOIUrl":"10.20407/fmj.2024-008","url":null,"abstract":"<p><p>Although organ transplantation is becoming general practice, little is known about the safety of delivery. This is the first known case that describes injury to the kidney by the uterine fundal pressure maneuver during cesarean section in a pancreas and kidney transplant recipient. A 40-year-old pregnant woman (gravida 0, para 0) was referred to our clinic. She had undergone living donor kidney transplantation 11 years earlier and brain-dead donor pancreas transplantation 1 year earlier owing to type 1 diabetes. Cesarean section was indicated when the patient's blood pressure was 150/100 mmHg at 37 weeks. We pushed the uterine fundus during delivery of the infant, with our usual caution. Serum creatinine levels were 1.6-2.6 mg/dl postoperatively. As this elevation was considered to be due to kidney graft dysfunction, we performed computed tomography, which revealed a hematoma around the kidney graft. Fifteen days after the cesarean section, surgical removal of the hematoma was performed by the transplant surgery team. Following hematoma removal, the serum creatinine level decreased to <1.4 mg/dl. We present a case of kidney graft injury during cesarean section in a pancreas and kidney transplant recipient.</p>","PeriodicalId":33657,"journal":{"name":"Fujita Medical Journal","volume":"11 1","pages":"52-53"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11782938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}