Infection Prevention in Practice最新文献

{"title":"Corrigendum to ‘Utilizing an adenosine triphosphate bioluminescence assay as an indicator of instrument and environmental cleanliness in the radiology department – a pilot study’ Infect Prev Pract, Volume 7 (2025) 100449","authors":"Wen-Chang Tseng , Yung-Cheng Wang , Wei-Chi Chen , Kang-Ping Lin","doi":"10.1016/j.infpip.2025.100466","DOIUrl":"10.1016/j.infpip.2025.100466","url":null,"abstract":"","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 2","pages":"Article 100466"},"PeriodicalIF":1.8,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144106225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of nosocomial pneumonia in two intensive care units of a French University Hospital from 2016 to 2022 in the era of COVID-19 pandemic","authors":"Sélilah Amour ,&nbsp;Elisabetta Kuczewski ,&nbsp;Elodie Marion ,&nbsp;Laurent Argaud ,&nbsp;Julien Crozon-Clauzel ,&nbsp;Anne Claire Lukaszewicz ,&nbsp;Philippe Vanhems ,&nbsp;Nagham Khanafer","doi":"10.1016/j.infpip.2025.100463","DOIUrl":"10.1016/j.infpip.2025.100463","url":null,"abstract":"<div><h3>Background</h3><div>Hospital-Acquired Pneumonia (HAP) are common in intensive care units (ICUs). The COVID-19 pandemic led to a global increase in healthcare-associated infections (HAI) among ICU patients. The aim of this study was to evaluate the trends in HAP incidence over a seven-year period of surveillance in two ICUs at a French University Hospital, and to assess the impact of COVID-19 (as well as the associated bacterial ecology).</div></div><div><h3>Methods</h3><div>A prospective surveillance of HAI in ICUs was conducted during the 1^st quarter of each year between 2016 and 2022 (2020: reference year). Socio-demographic, clinical and bacteriological data were collected and the incidence of HAP was calculated. Poisson regressions were done and crude and adjusted incidence rate ratio were calculated.</div></div><div><h3>Results</h3><div>1,797 patients were included, with 61.3% of male and a median age of 67 years. The median duration of intubation was 4 days (7 days in 2021 and 5 days in 2022). The proportion of COVID-19 patients was 45.7% in 2021 and 24.1% in 2022. Compared to 2020, the incidence of HAP increased in both 2021 [cIRR: 2.34 (95%CI: 1.30–4.23) and aIRR: 2.26 (95%CI: 1.25–4.08)] and 2022 [cIRR: 1.79 (95%CI: 0.97–3.32) and aIRR: 1.66 (95%CI: 0.90–3.07)]. The most commonly identified microorganisms were Enterobacteriaceae (42.4%), with a significantly higher incidence of HAP due to Enterobacteriaceae in COVID-19 patients.</div></div><div><h3>Conclusions</h3><div>These results indicate an increase of HAP incidence in 2021 and 2022, mainly caused by <em>Enterobacteriaceae</em> in COVID-19 patients. This trend needs to be confirmed or refuted in the post-pandemic era.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 2","pages":"Article 100463"},"PeriodicalIF":1.8,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144083689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"World Hand Hygiene Day 2025: A perspective from the Infection Prevention in Practice Editors","authors":"Siobhain Kelly ,&nbsp;Gemma Winzor ,&nbsp;Simon Ching Lam","doi":"10.1016/j.infpip.2025.100465","DOIUrl":"10.1016/j.infpip.2025.100465","url":null,"abstract":"","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 2","pages":"Article 100465"},"PeriodicalIF":1.8,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143916621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical risk factors for postoperative infection in adult cardiac surgery with cardiopulmonary bypass: a retrospective study","authors":"Guangxu Mao ,&nbsp;Wensen Chen ,&nbsp;Liyun Wang ,&nbsp;Sheng Zhao ,&nbsp;Feng Zang","doi":"10.1016/j.infpip.2025.100458","DOIUrl":"10.1016/j.infpip.2025.100458","url":null,"abstract":"<div><h3>Background</h3><div>Postoperative infection remains a serious problem for patients undergoing open-heart surgery and is associated with poor prognosis and mortality.</div></div><div><h3>Aim</h3><div>To determine the incidence, characteristics and associated risk factors for nosocomial infections in adult cardiac surgery patients and to develop a nomogram prediction model.</div></div><div><h3>Methods</h3><div>Data were retrospectively collected from patients who underwent cardiac surgery with cardiopulmonary bypass (CPB) at a tertiary hospital in 2023. Patients were divided into an infected group (<em>N</em> = 130) and a non-infected group (<em>N</em> = 192). Multivariate logistic regression analysis was used to analyse the independent risk factors for healthcare-associated infections after cardiac surgery under CPB.</div></div><div><h3>Results</h3><div>Of the 1584 patients, 130 (8.21%) developed postoperative infections (infection group). Lower respiratory tract was the most common site of infection (<em>N</em> = 74, 56.9%), while Gram-negative bacteria were the predominant isolates overall (<em>N</em> = 81, 62.3%). Among the Gram-negative bacteria, <em>Acinetobacter baumannii</em> was the most frequently identified, whereas <em>Staphylococcus aureus</em> was the leading strain among Gram-positive bacteria. Multivariate logistic regression analysis of the 322 patients included in the study revealed that CPB duration, American Society of Anaesthesiologists score, procalcitonin concentration on the first postoperative day, monocyte:lymphocyte ratio, preinfection mechanical ventilation duration, and preinfection central venous catheterization duration were the six independent predictors of postoperative infection. The area under the receiver operating characteristic curve was 0.824 (0.778–0.870), and the model showed good predictive performance.</div></div><div><h3>Conclusion</h3><div>A nomogram has been developed to predict postoperative infection via commonly available data. This tool could assist clinicians in optimising the perioperative care of patients undergoing cardiac surgery with CPB, but further external validation is needed.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 2","pages":"Article 100458"},"PeriodicalIF":1.8,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143874603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new classification of personal protective equipment in healthcare settings: Enhancing infection control and prevention","authors":"Hui Jin ,&nbsp;Qun Lu ,&nbsp;Kaiwen Ni ,&nbsp;Xiaoping Ni","doi":"10.1016/j.infpip.2025.100460","DOIUrl":"10.1016/j.infpip.2025.100460","url":null,"abstract":"","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 2","pages":"Article 100460"},"PeriodicalIF":1.8,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143830093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MRSA: the enduring foe","authors":"Siobhain Kelly ,&nbsp;Gemma Winzor ,&nbsp;Simon Ching Lam","doi":"10.1016/j.infpip.2025.100459","DOIUrl":"10.1016/j.infpip.2025.100459","url":null,"abstract":"","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 2","pages":"Article 100459"},"PeriodicalIF":1.8,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144146825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of heparin–vancomycin–amikacin combination lock in preventing catheter-related infections in haemodialysis patients: a double-blind randomized clinical trial","authors":"A.A. Arabzadeh ,&nbsp;M. Iranikia ,&nbsp;F. Pourfarzi ,&nbsp;B. Shahrami ,&nbsp;S. M Kebar","doi":"10.1016/j.infpip.2025.100457","DOIUrl":"10.1016/j.infpip.2025.100457","url":null,"abstract":"<div><h3>Background</h3><div>Haemodialysis patients with tunnelled central venous catheters (CVCs) are at high risk for catheter-related infections (CRIs), which can lead to serious complications, prolonged hospitalizations, and increased healthcare costs. The use of antibiotic lock solutions may help prevent these infections. This study evaluates the efficacy of a heparin–vancomycin–amikacin combination lock solution in preventing CRIs compared with heparin alone in haemodialysis patients.</div></div><div><h3>Methods</h3><div>This single-centre, double-blind randomized clinical trial involved 60 haemodialysis patients with tunnelled CVCs. Patients were randomly assigned to receive either a heparin 5000 units/mL lock (Group A) or a combination of heparin 5000 units/mL, vancomycin 500 mg/mL, and amikacin 500 mg/mL lock (Group B). The primary outcome was the incidence of CRIs, diagnosed using CDC criteria, over a 6-month follow-up period.</div></div><div><h3>Findings</h3><div>Group B demonstrated a significantly lower incidence of CRIs compared to Group A (<em>P</em>=0.001). Additionally, the mean number of CRI episodes per patient and the CRI rate per 1000 catheter days were significantly lower in Group B (<em>P</em>=0.028 and 0.042, respectively). The rate of catheter removal due to infection was also significantly reduced in Group B (<em>P</em>=0.029). No significant differences in infection timing were observed, although Group B showed later infection onset. No adverse drug reactions were reported.</div></div><div><h3>Conclusions</h3><div>The heparin–vancomycin–amikacin combination lock solution was more effective in preventing CRIs than heparin alone in haemodialysis patients. Further studies with larger sample sizes and longer follow-up are needed to confirm its long-term benefits and assess potential risks, including antibiotic resistance.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 2","pages":"Article 100457"},"PeriodicalIF":1.8,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of relative humidity distribution and its impact on disinfection using a combination of robotic fogger and hydrogen peroxide","authors":"Prasanna Kumar Sistla,&nbsp;P. Kanaka Raju","doi":"10.1016/j.infpip.2025.100452","DOIUrl":"10.1016/j.infpip.2025.100452","url":null,"abstract":"<div><h3>Background</h3><div>Relative humidity is a key factor in the disinfection process.</div></div><div><h3>Aim</h3><div>To examine the distribution of relative humidity, and the time required to reach its mean value in the target area when using a robotic fogger with 7.4% hydrogen peroxide.</div></div><div><h3>Methods</h3><div>The study evaluated the device in both stationary and mobile operation modes. In each mode, relative humidity sensors, along with chemical, biological, and enzyme indicators, were employed to assess the disinfection's effectiveness and consistency.</div></div><div><h3>Results</h3><div>The device dispersed disinfectant at a rate of 30 mL/min over 45 min in both modes. A shorter time to reach the mean relative humidity is desirable for effective disinfection. It was observed that the mobile mode reached the mean relative humidity 50% faster, maintained this level for an additional 30 min, and achieved an 11% higher relative humidity compared to the stationary mode.</div></div><div><h3>Conclusion</h3><div>These advancements could assist pharmaceutical manufacturing and healthcare facilities in minimizing downtime during periodic disinfection.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 2","pages":"Article 100452"},"PeriodicalIF":1.8,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143686274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of a patient empowerment hand hygiene programme: a single-centre study in Japan","authors":"Yusuke Watanabe ,&nbsp;Asami Okugawa ,&nbsp;Hiroshi Soeda ,&nbsp;Tomohide Shimodaira ,&nbsp;Satoko Sato ,&nbsp;Hiroaki Fujita ,&nbsp;Takehito Kobayashi ,&nbsp;Itaru Nakamura ,&nbsp;Hidehiro Watanabe","doi":"10.1016/j.infpip.2025.100456","DOIUrl":"10.1016/j.infpip.2025.100456","url":null,"abstract":"<div><div>The effectiveness of patient participation in hand hygiene (HH) programmes in Japan is unclear. This study examines the effect of a patient empowerment HH programme at a Japanese hospital. Two periods were analysed: January 2020 to November 2020 as the baseline, and December 2020 to April 2021 as the intervention period. The intervention involved inpatients observing the HH practices of healthcare workers. The average number of HH events per patient-day increased from 23.4 at baseline to 37.3 during the intervention. HH events were positively correlated with the number of patient observations. Patient empowerment programmes may therefore help to improve HH.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 2","pages":"Article 100456"},"PeriodicalIF":1.8,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143643588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers to hand hygiene practice among healthcare workers in health centres of Kirkos and Akaki Kality sub-cities, Addis Ababa, Ethiopia: a qualitative study","authors":"Asmamaw Deguale Worku ,&nbsp;Abayneh Melaku","doi":"10.1016/j.infpip.2025.100450","DOIUrl":"10.1016/j.infpip.2025.100450","url":null,"abstract":"<div><h3>Background</h3><div>Hand hygiene is an easy step to reduce healthcare-acquired infections, and improve patient safety. Major progress in facility accessibility was made during the coronavirus disease 2019 (COVID-19) pandemic, and this led to greater adherence to hand hygiene practices. However, handwashing practices have now returned to the pre-COVID-19 era. Most of the studies that have investigated hand hygiene adherence are quantitative. As such, this study aimed to explore barriers to hand hygiene practice in the health centres of Kirkos and Akaki Kality sub-cities in Addis Ababa, Ethiopia.</div></div><div><h3>Methods</h3><div>Twenty-four healthcare professionals employed at the aforementioned health centres were interviewed using the key informant interview method. Data were analysed using a qualitative content analysis technique.</div></div><div><h3>Results</h3><div>Based on the findings, there were three main categories of barriers to hand hygiene practice: barriers related to individuals (including three sub-categories: lack of knowledge and skill, improper attitude, and poor attention and negligence of healthcare workers); leadership barriers (including two sub-categories: lack of dedicated staff and low attention of leaders); and institutional barriers (including three sub-categories: inappropriate infrastructure and lack of resources, shortage of water, and high work load and staff turnover).</div></div><div><h3>Conclusion</h3><div>There were several reasons why hand hygiene guidance was not followed. Hand hygiene barriers can be minimized by displaying colour-coded notice boards, making washing facilities easily accessible, monitoring the availability of soap, offering training, and providing accurate evidence about the need to enhance hand hygiene.</div></div>","PeriodicalId":33492,"journal":{"name":"Infection Prevention in Practice","volume":"7 2","pages":"Article 100450"},"PeriodicalIF":1.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143628104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}