International Journal of Biological Macromolecules最新文献_第3页

Bimetallic CuMn nanozyme-enzyme microsystem for efficient dimethyl phthalate degradation.

IF 7.7 1区化学

International Journal of Biological Macromolecules Pub Date : 2025-01-01 Epub Date: 2024-11-27 DOI: 10.1016/j.ijbiomac.2024.138145

Yifan Zeng, Shiyong Sun, Sen Lin, Rui Lv, Ke Wang, Jianjun Deng

{"title":"Bimetallic CuMn nanozyme-enzyme microsystem for efficient dimethyl phthalate degradation.","authors":"Yifan Zeng, Shiyong Sun, Sen Lin, Rui Lv, Ke Wang, Jianjun Deng","doi":"10.1016/j.ijbiomac.2024.138145","DOIUrl":"10.1016/j.ijbiomac.2024.138145","url":null,"abstract":"Recently, the synthesis of nanozymes-enzyme microsystems with high catalytic stability provides new opportunities for treating diverse pollutants in complex aquatic systems. Herein, a carboxyl-functionalized CuMn bimetallic nanozyme-enzyme microsystem (CMAC@Lipase) was successfully constructed by combining copper‑manganese based aminoclays (CMAC) with lipase. This system exhibited laccase-like catalytic activity facilitated by CuMn electron transfer, while enhancing lipase stability via its carrier function. Under alkaline conditions at pH 10, CMAC@Lipase catalyzed the hydrolysis of p-NPP (280 nm) to produce p-NP (400 nm), and subsequently reduced p-NP to p-AP within 30 min with the assistance of NaBH4. Furthermore, it effectively degraded 72.8 % of dimethyl phthalate (DMP) at 40 mg·L-1 under alkaline conditions within 48 h, maintaining a 53.5 % degradation rate after 10 reuse cycles. This work provided a new strategy for the design of nanozyme-enzyme microsystems and a new research idea for the efficient treatment of contaminants in actual aqueous environments.","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":" ","pages":"138145"},"PeriodicalIF":7.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142754418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of enzymatic modification on the structure, antioxidant activity, and prebiotic activity of ginseng neutral polysaccharide. 酶解对人参中性多糖结构、抗氧化活性和益生活性的影响

IF 7.7 1区化学

International Journal of Biological Macromolecules Pub Date : 2025-01-01 Epub Date: 2024-11-24 DOI: 10.1016/j.ijbiomac.2024.138007

Binbin Dong, Zong Hou, Zhong Zheng, Junpeng Xing, Ningning Zhao, Zhiqiang Liu, Shu Liu

{"title":"Influence of enzymatic modification on the structure, antioxidant activity, and prebiotic activity of ginseng neutral polysaccharide.","authors":"Binbin Dong, Zong Hou, Zhong Zheng, Junpeng Xing, Ningning Zhao, Zhiqiang Liu, Shu Liu","doi":"10.1016/j.ijbiomac.2024.138007","DOIUrl":"10.1016/j.ijbiomac.2024.138007","url":null,"abstract":"The abundant ginseng neutral polysaccharide (GPN) has been neglected due to its lower activity compared to acidic polysaccharide in ginseng. Herein, the composite enzymes were used to modify the GPN and obtained the enzymatic-degradation-GPN (EGPN). The structural changes were further characterized by GPC, FT-IR, Congo red, XRD, zeta potential, TG, cryo-SEM and AFM. The antioxidant activity of GPNs in vitro was investigated by in vitro chemical experiments and oxidative stress-related indicators on PC12 cells damaged by Aβ25-35, and EGPN showed favorable antioxidant activity. In addition, EGPN metabolized by intestinal microbiota also significantly increased the viability of injured PC12 cells. Furthermore, in vitro fermentation model was used to investigate the differences of physicochemical properties of GPNs and their regulatory effects on the microbiota. EGPN enhanced the diversity of the microbiota and increased the concentration of short-chain fatty acids (SCFAs). Importantly, EGPN demonstrated a significant reduction in the presence of detrimental bacteria such as Enterococcus and Allobaculum, while simultaneously promoting the growth of beneficial microorganisms including Lactobacillus, Prevotella, and Ruminococcu. This study highlights the potential use of EGPN prepared by composite enzymatic degradation in antioxidant, neuroprotection and restoration of intestinal homeostasis.","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":" ","pages":"138007"},"PeriodicalIF":7.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142724670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficient lead ion removal from aqueous solutions for wastewater treatment using a novel cross-linked alginate-rice husk ash-graphene oxide-chitosan nanocomposite. 利用新型交联海藻-稻壳灰-氧化石墨烯-壳聚糖纳米复合材料高效去除废水处理水溶液中的铅离子。

IF 7.7 1区化学

International Journal of Biological Macromolecules Pub Date : 2025-01-01 Epub Date: 2024-11-26 DOI: 10.1016/j.ijbiomac.2024.137983

Amal A Nassar, Mahmoud F Mubarak, Ayman K El-Sawaf, Mohamed A Zayed, Mohamed Hemdan

{"title":"Efficient lead ion removal from aqueous solutions for wastewater treatment using a novel cross-linked alginate-rice husk ash-graphene oxide-chitosan nanocomposite.","authors":"Amal A Nassar, Mahmoud F Mubarak, Ayman K El-Sawaf, Mohamed A Zayed, Mohamed Hemdan","doi":"10.1016/j.ijbiomac.2024.137983","DOIUrl":"10.1016/j.ijbiomac.2024.137983","url":null,"abstract":"This research introduces an innovative composite, the cross-linked alginate-rice husk ash-graphene oxide-chitosan nanoparticles (CL-ARCG-CNP), designed for the effective adsorption of lead ions (Pb2+) in water treatment applications. Comprehensive characterization was performed using techniques such as Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), High-Resolution Transmission Electron Microscopy (HR TEM), Selected Area Electron Diffraction (SAED), Atomic Force Microscopy (AFM), Thermogravimetric Analysis (TGA), and Brunauer-Emmett-Teller (BET) analysis. These analyses revealed notable structural and morphological features. The CL-ARCG-CNP composite demonstrated a significant surface area of approximately 148.44 m2/g, achieving an impressive adsorption capacity of 242.5 mg/g and a removal efficiency of 95.2 % after 240 min of contact duration. The adsorption process conformed to the Freundlich isotherm model (R2: 0.998) and the pseudo-second-order kinetic model (R2: 0.9992). Thermodynamic studies confirmed the spontaneity and endothermic nature of the adsorption process. Reusability tests showed that the composite could be reused for up to five cycles with minimal loss in adsorption capacity. These findings indicate that the CL-ARCG-CNP composite is highly effective for the removal of Pb2+ ions from aqueous solutions, making it a promising material for wastewater treatment.","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":" ","pages":"137983"},"PeriodicalIF":7.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142724518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to "Harnessing the targeting potential of hyaluronic acid for augmented anticancer activity and safety of duvelisib-loaded nanoparticles in hematological malignancies" [Int. J. Biol. Macromol. 282 (2024) 136600].

IF 7.7 1区化学

International Journal of Biological Macromolecules Pub Date : 2025-01-01 Epub Date: 2024-12-03 DOI: 10.1016/j.ijbiomac.2024.138183

Srushti Mahajan, Mayur Aalhate, Essha Chatterjee, Hoshiyar Singh, Anamika Sharma, Indrani Maji, Ujala Gupta, Santosh Kumar Guru, Pankaj Kumar Singh

引用次数: 0

Highly efficient biosynthesis of 6'-sialyllactose in a metabolically engineered plasmid-free Escherichia coli using a novel α2,6-sialyltransferase from Nicoletella semolina.

IF 7.7 1区化学

International Journal of Biological Macromolecules Pub Date : 2025-01-01 Epub Date: 2024-11-27 DOI: 10.1016/j.ijbiomac.2024.138151

Yuanlin Liu, Liping Qiao, Lumeng Yu, Qian Lin, Ruiyan Wang, Yingying Zhu, Wanmeng Mu

{"title":"Highly efficient biosynthesis of 6'-sialyllactose in a metabolically engineered plasmid-free Escherichia coli using a novel α2,6-sialyltransferase from Nicoletella semolina.","authors":"Yuanlin Liu, Liping Qiao, Lumeng Yu, Qian Lin, Ruiyan Wang, Yingying Zhu, Wanmeng Mu","doi":"10.1016/j.ijbiomac.2024.138151","DOIUrl":"10.1016/j.ijbiomac.2024.138151","url":null,"abstract":"6'-Sialyllactose (6'-SL), one of the most prevalent sialylated human milk oligosaccharides (HMOs), has recently garnered significant attention due to its promising health effects for infants. In this study, the 6'-SL biosynthetic pathway in EZAK (E. coli BL21(DE3) ΔlacZΔnanAΔnanK) was initially constructed by introducing a plasmid expressing the precursor CMP-Neu5Ac synthesis pathway genes neuBCA. A novel α2,6-sialyltransferase Ev6ST (NCBI Reference Sequence: WP_132500470) was selected by introducing plasmids expressing various α2,6-sialyltransferase-encoding genes and subsequent comparisons of the yields of 6'-SL. Subsequently, by integrating neuBCA and ev6st individually or in combination on the chromosome of EZAK, the high-yielding plasmid-free strain EZAKBEP with an extracellular yield of 5.68 g/L. In the 5 L bioreactor, fed-batch fermentation resulted in an extracellular yield of 15.35 g/L of 6'-SL. This work successfully screened a high-efficiency α2,6-sialyltransferase Ev6ST and constructed a high-yielding strain EZAKBEP under plasmid-free conditions, which is the highest yield of shake flask fermentation to date, and provides some reference significance for subsequent research.","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":" ","pages":"138151"},"PeriodicalIF":7.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142754427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reconstruction of biorefinery lignin into nanoparticles with controlled morphology and structure.

IF 7.7 1区化学

International Journal of Biological Macromolecules Pub Date : 2025-01-01 Epub Date: 2024-11-28 DOI: 10.1016/j.ijbiomac.2024.138161

Sang-Mook You, Jonghwa Kim, Suin Bae, Hyeon Soo Jang, Chan-Duck Jung, Hyolin Seong, Younghoon Kim, Hyun Gil Cha, June-Ho Choi, Hoyong Kim

{"title":"Reconstruction of biorefinery lignin into nanoparticles with controlled morphology and structure.","authors":"Sang-Mook You, Jonghwa Kim, Suin Bae, Hyeon Soo Jang, Chan-Duck Jung, Hyolin Seong, Younghoon Kim, Hyun Gil Cha, June-Ho Choi, Hoyong Kim","doi":"10.1016/j.ijbiomac.2024.138161","DOIUrl":"10.1016/j.ijbiomac.2024.138161","url":null,"abstract":"Lignin nanoparticles (LNPs) exhibit application potential in fields such as ultraviolet (UV) shielding, antioxidant materials, and water purification owing to their versatile chemical structure. However effective, nontoxic solvent-based strategies to synthesize LNPs with diverse morphologies have not been reported. This study presents a continuous biorefinery method to produce monodisperse LNPs with diverse morphologies from isopropanol-solubilized lignin (IPA-lignin). IPA-lignin, which is rich in hydroxyl and carboxyl groups, was extracted from sweet sorghum bagasse via disc refining. The recovered IPA was reused with IPA-lignin to generate LNPs with hollow to dense structures at various temperatures. Morphology control was achieved by modulating the interaction between IPA and distilled water (DIW), an antisolvent. The interplay between IPA and DIW, coupled with the self-assembly kinetics of the lignin molecules, affected the encapsulated DIW content of the final materials, resulting in particles with different densities. The resulting LNPs exhibited varied surface chemistries, leading to diverse UV protection (maximum absorbance wavelength = 361 nm), antioxidant (half-maximal inhibitory concentration = 0.48 mg/mL), and selective cationic dye adsorption (over 90 %) properties. The correlation between the properties of the LNPs and their applications was then assessed to offer valuable insights into their functional optimization.","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":" ","pages":"138161"},"PeriodicalIF":7.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142754442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling the role of mechanical process intensifications and chemical additives in boosting lipase-catalyzed hydrolysis of vegetable oil for fatty acid production: A comprehensive review.

IF 7.7 1区化学

International Journal of Biological Macromolecules Pub Date : 2025-01-01 Epub Date: 2024-11-28 DOI: 10.1016/j.ijbiomac.2024.138144

Wei Zhe Ng, Eng-Seng Chan, Wail Gourich, Siti Hanifah Adiiba, Min Ying Liow, Chien Wei Ooi, Beng Ti Tey, Cher Pin Song

{"title":"Unveiling the role of mechanical process intensifications and chemical additives in boosting lipase-catalyzed hydrolysis of vegetable oil for fatty acid production: A comprehensive review.","authors":"Wei Zhe Ng, Eng-Seng Chan, Wail Gourich, Siti Hanifah Adiiba, Min Ying Liow, Chien Wei Ooi, Beng Ti Tey, Cher Pin Song","doi":"10.1016/j.ijbiomac.2024.138144","DOIUrl":"10.1016/j.ijbiomac.2024.138144","url":null,"abstract":"The enzymatic production of fatty acids from vegetable oils is becoming a preferred method due to its mild conditions, simplicity, and scalability. This review analyzes studies on enzymatic hydrolysis, exploring various feedstocks, lipases, reaction conditions, and conversion yields. However, a key limitation is the longer reaction time compared to conventional methods. This limitation is primarily due to the immiscibility of triacylglycerols (TAGs) with water at low temperatures and pressures, as well as the lower activity of enzymes compared to chemical catalysts. To overcome these issues, chemical additives are identified as the most effective process intensification strategy. They are easy to implement, cause less damage to lipases, and are more efficient than mechanical methods. The impact of various chemical additives was thoroughly examined for potential improvements in the enzymatic hydrolysis of vegetable oils. A synergistic combination of chemical additives comprising ionic liquids (ILs) and polyols, along with ultrasound, as well as the consideration of immobilization techniques were explored. Overall, this review highlights the potential of chemical additives and their synergistic feasibility in enhancing the enzymatic performance of lipase-catalyzed hydrolysis reactions.","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":" ","pages":"138144"},"PeriodicalIF":7.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142754353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrochemical quantification based on the interactions of nucleoside analog cladribine with dsDNA via experimental and in-silico studies.

IF 7.7 1区化学

International Journal of Biological Macromolecules Pub Date : 2025-01-01 Epub Date: 2024-11-28 DOI: 10.1016/j.ijbiomac.2024.138083

Pelin Şenel, Abdullah Al Faysal, Soykan Agar, Mine Yurtsever, Ayşegül Gölcü

{"title":"Electrochemical quantification based on the interactions of nucleoside analog cladribine with dsDNA via experimental and in-silico studies.","authors":"Pelin Şenel, Abdullah Al Faysal, Soykan Agar, Mine Yurtsever, Ayşegül Gölcü","doi":"10.1016/j.ijbiomac.2024.138083","DOIUrl":"10.1016/j.ijbiomac.2024.138083","url":null,"abstract":"Cladribine is a deoxyadenosine analog prodrug originally developed to treat hairy-cell leukemia and other lymphoproliferative diseases. However, it is now primarily used in the treatment of relapsing types of multiple sclerosis (MS). Understanding how medications interact with dsDNA is crucial for developing more effective and efficient medications. This study aims to examine the binding behavior of cladribine with dsDNA via various analytical methods, such as heat denaturation, UV spectroscopy, fluorescence spectroscopy, electrochemistry, and viscosity tests. The binding constant (Kb) of cladribine with dsDNA has been estimated to be 2.41 × 104 ± 0.20 at 298 K using the Benesi-Hildebrand plot. Molecular docking simulations were employed to explore the dsDNA-cladribine interactions quantitatively at the molecular level. Molecular Dynamic simulations were performed to follow the stability of drug-bound DNA for 50 ns. The simulations revealed that cladribine binds to dsDNA via the minor groove region of DNA by forming hydrogen bonds mainly with Guanine's DNA bases. The post-MD analyses enabled us to follow the stability of DNA and cladribine complex. Additionally, two methods based on the electrochemical approach were developed in this study for low-level cladribine assessment using differential pulse voltammetry (DPV). The first method relies on cladribine oxidation in pH 2 phosphate buffer, while the second method uses deoxyguanosine oxidation signals resulting from cladribine and dsDNA binding in pH 4.80 acetate buffer. The analytical efficacy of the two methods was verified using cladribine concentrations ranging from 2 to 25 μM, with a limit of detection (LOD) of 0.30 and 0.92 μM, respectively. Furthermore, the study conducted percent recovery tests by employing pharmaceutical injection using both established methodologies.","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":" ","pages":"138083"},"PeriodicalIF":7.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142754425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastro retentive floating drug delivery system of levofloxacin based on Aloe vera hydrogel: In vitro and in vivo assays.

IF 7.7 1区化学

International Journal of Biological Macromolecules Pub Date : 2025-01-01 Epub Date: 2024-11-28 DOI: 10.1016/j.ijbiomac.2024.138156

Fouzia Feroze, Muhammad Sher, Muhammad A Hussain, Azhar Abbas, Muhammad T Haseeb, Arooj Fatima, Muhammad Naeem-Ul-Hassan, Hatem M A Amin

{"title":"Gastro retentive floating drug delivery system of levofloxacin based on Aloe vera hydrogel: In vitro and in vivo assays.","authors":"Fouzia Feroze, Muhammad Sher, Muhammad A Hussain, Azhar Abbas, Muhammad T Haseeb, Arooj Fatima, Muhammad Naeem-Ul-Hassan, Hatem M A Amin","doi":"10.1016/j.ijbiomac.2024.138156","DOIUrl":"10.1016/j.ijbiomac.2024.138156","url":null,"abstract":"Gastro retentive drug delivery systems (GRDDS) have gained immense popularity as they reduce dosing frequency, improve bioavailability, and enhance patient compliance. Herein, a plant-based, controlled swelling, and pH-sensitive GRDDS based on Aloe vera hydrogel and cellulose was developed for the sustained release of levofloxacin (LEVO). The properties of five various floating tablet formulations including dynamic swelling, pH-responsiveness, hardness, friability, drug release, and buoyant time were evaluated. The optimized formulation (FF) was characterized using FTIR and SEM, and the surface morphology exhibited a porous texture with microchannels that facilitated tablet swelling and prolonged release of LEVO. The formulation FF remained buoyant (> 12 h) in the simulated gastric fluid with a buoyancy time of 303 s. A pH-dependent swelling behavior of the formulation FF was revealed with the highest swelling (7.1 g/g) in water, followed by buffers of pH 6.8 (5.4 g/g), 4.5 (3.8 g/g), and 1.2 (2 g/g). The controlled release of LEVO was demonstrated for >12 h following the Hixson-Crowell model and non-Fickian diffusion. Pharmacokinetic parameters of LEVO were determined using in vivo studies. The non-toxic nature of the formulation under study was demonstrated. The results render this approach promising in reducing the dosing frequency, suggesting its potential for clinical applications.","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":" ","pages":"138156"},"PeriodicalIF":7.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142754426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of 2-octenyl-1-succinic anhydride (OSA) concentration on the functional, rheological, structural and flow properties of starch from Indian Teff (Eragrostis tef).

IF 7.7 1区化学

International Journal of Biological Macromolecules Pub Date : 2025-01-01 Epub Date: 2024-11-28 DOI: 10.1016/j.ijbiomac.2024.138055

Aditi Sharma, Navdeep Jindal, Sukhcharn Singh

{"title":"Influence of 2-octenyl-1-succinic anhydride (OSA) concentration on the functional, rheological, structural and flow properties of starch from Indian Teff (Eragrostis tef).","authors":"Aditi Sharma, Navdeep Jindal, Sukhcharn Singh","doi":"10.1016/j.ijbiomac.2024.138055","DOIUrl":"10.1016/j.ijbiomac.2024.138055","url":null,"abstract":"Teff (Eragrostis tef) starch was esterified using 2-octenyl-1-succinic anhydride (OSA) (1 to 3 %), resulting in degrees of substitution (DS) 0.007-0.020. The functional, flowability, pasting, rheological, thermal, and structural properties of the modified starches were investigated. The amorphous regions of the starch granules were more reactive to the modification than the crystalline regions, potentially affecting the strength of the amorphous regions while leaving the crystalline structure intact. The primary factor influencing the pasting and thermal properties of the OSA-modified starches was the amylose content, which decreased significantly upon esterification. OSA modification increased the water solubility and swelling power of the starch. Rheological tests indicated that with increasing DS, the pasting temperature reduced from 77.59 °C to 76.81 °C, while the pasting viscosity increased. Thermograms showed lower onset, peak, end temperatures, and enthalpy of gelatinization in OSA-modified starches compared to their native counterparts. No significant changes were observed in the X-ray diffractograms, verifying the absence of reaction in the crystalline region. The results of FTIR and NMR confirmed the successful reaction between OSA and starch by formation of new peaks. These findings demonstrate that OSA-modified starches possess distinct properties that can meet various requirements in the development of new products.","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":" ","pages":"138055"},"PeriodicalIF":7.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142754433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0