International Journal of Biological Macromolecules最新文献

{"title":"Effect of citric acid on the blends of poly butylene succinate and thermoplastic corn starch","authors":"Hrushikesh B. Patil ,&nbsp;Vasanth Kumar ,&nbsp;Dnyaneshwar J. Kumavat ,&nbsp;Divya Mishra ,&nbsp;Adarsh R. Rao","doi":"10.1016/j.ijbiomac.2025.143537","DOIUrl":"10.1016/j.ijbiomac.2025.143537","url":null,"abstract":"<div><div>This research focuses on the development of environmentally friendly and cost-effective materials by blending Poly (Butylene Succinate) (PBS) with thermoplastic corn starch (TPS). The study investigates the impact of incorporating citric acid (CA) and citric acid-modified castor oil polyurethane (PUCA) as compatibilizers in PBS/TPS (70:30) blends. Reactive extrusion is employed to prepare the blends, varying the proportions of CA (1 %, 3 %, and 5 %) and PUCA (10 %, 20 %, and 30 %). Comprehensive analyses of mechanical properties such as tensile strength and elongation at break, thermal behavior including melting and crystallization temperatures, rheological properties, morphological characteristics observed through scanning electron microscopy, and biodegradation effects provide valuable insights into the influence of CA content on the blend performance. These findings contribute to the design of sustainable materials suitable for applications such as food packaging, agricultural films, and single-use products. The investigation also sheds light on the potential of PBS/TPS blends as eco-friendly alternatives in various industries.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"311 ","pages":"Article 143537"},"PeriodicalIF":7.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143904279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydration-responsive keratin fibers with ultra-high shape recovery via reversible protein conformational change and Au enhancement","authors":"Xiaoyun Xu ,&nbsp;Zhuang Wang ,&nbsp;Qi Zhang ,&nbsp;Ke Zhang ,&nbsp;Min Li ,&nbsp;Jieqiong Yang ,&nbsp;Yi Zhao ,&nbsp;Qinfei Ke ,&nbsp;Qingbao Guan ,&nbsp;Jinlian Hu","doi":"10.1016/j.ijbiomac.2025.143620","DOIUrl":"10.1016/j.ijbiomac.2025.143620","url":null,"abstract":"<div><div>Fabricating shape-memory materials from natural macromolecules has gained popularity to facilitate the development of bio-friendly smart materials and devices. However, current biobased shape-memory materials have shortcomings, including insufficient mechanical properties and low shape recovery rate in their real applications. Herein, this work aims to develop hierarchically structured keratin-based fibers with high strength and shape-memory properties in response to hydration. The gold nanoparticle is adopted for enhancement in the keratin system, and a well-aligned anisotropic structure with α-helix to the fiber axis is established in the regenerated keratin fibers by wet spinning. The strong crosslinking effect from Au<img>S bonding endows the keratin fibers with outstanding shape-memory performance, exhibiting a shape fixity of ~92 % and a near-full shape recovery rate of ~96 %. In this system, the transition between α and β conformation under external force and water stimulation is assigned as the fundamental mechanism in response to hydration. In hydration and dehydration, the hydrogen bonds act as ‘switches’ that enable deformation, while the strong Au<img>S bonds are ‘net points’ to maintain the original and temporary shapes. This strategy can promote metal nanomaterial anchoring as a methodology for fabricating shape-memory protein-based fibers with excellent mechanical properties and shape-memory performance.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"311 ","pages":"Article 143620"},"PeriodicalIF":7.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143890928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CsABF8 mediates drought-induced ABA signaling in the regulation of raffinose biosynthesis in Camellia sinensis leaves","authors":"Dongqiao Zheng ,&nbsp;Maoyin Fu ,&nbsp;Chenyi Sun ,&nbsp;Qiqi Yang ,&nbsp;Xinmeng Zhang ,&nbsp;Jing Lu ,&nbsp;Manman Chang ,&nbsp;Linlin Liu ,&nbsp;Xiaochun Wan ,&nbsp;Qi Chen","doi":"10.1016/j.ijbiomac.2025.143521","DOIUrl":"10.1016/j.ijbiomac.2025.143521","url":null,"abstract":"<div><div>Drought has become an important environmental stress limiting the growth and development of <em>Camellia sinensis</em> due to its moisture-loving and temperature-tolerant nature. ABA-response element binding factor (ABFs) is a key transcriptional regulator in the ABA signaling pathway that regulates plant responses to hormones and adversity. However, their roles and regulatory mechanisms in tea tree remain unknown. To investigate the drought response in <em>Camellia sinensis</em>, drought-sensitive (Fuyun No.6, FY) and drought-tolerant (Taicha No.12, TC) tea cultivars were treated with exogenous PEG and ABA and subjected to non-targeted metabolomics by Ultra Performance Liquid Chromatography-Electrospray Ionization-Triple Quadrupole tandem Mass Spectrometry (UPLC/ESI-Q TRAP-MS/MS). The bioactive carbohydrates galactinol and raffinose were identified as potential drought regulators. Analysis of transcriptomics data identified potential drought tolerant target genes, namely <em>CsGolS1/2</em>, encoding galactinol synthases, <em>CsRaf6</em>, a raffinose synthase, and <em>CsABF8</em>, a transcriptional regulator in the ABA-response element binding factor family. The tea CsSnRK2.8-CsABF8-CsGolS1/CsGolS2/CsRaf6 regulatory module induced in response to drought stress was constructed using multiple molecular validation tools. This preliminary analysis of the molecular mechanism by which CsABF8, a regulator on the ABA signaling pathway, mediates the differences in drought tolerance in different tea cultivars provides a theoretical basis for the selection and breeding of drought-resistant varieties.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"311 ","pages":"Article 143521"},"PeriodicalIF":7.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143890930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progress in galactomannan-based materials for biomedical application","authors":"Joice M. Scheibel ,&nbsp;Nataly M. Siqueira ,&nbsp;Laiane S. da Silva ,&nbsp;Manoela A.M. Mace ,&nbsp;Rosane M.D. Soares","doi":"10.1016/j.ijbiomac.2025.143614","DOIUrl":"10.1016/j.ijbiomac.2025.143614","url":null,"abstract":"<div><div>Galactomannan-based biomaterials display a unique behavior in aqueous media due to their mechanical, rheological and solubility properties, which are increasingly attracting their applicability into the biomedical area. The physical-chemical features of galactomannans extracted from different botanical sources provide diverse applicability for the developed systems, which can deliver active substances and be applied in wound healing and bone replacement. Galactomannans have an essential biological role and can be easily chemically modified due to their reactive chemical structure. Besides, their biocompatibility and capacity to be applied in the form of film, hydrogel, micro, nanoparticles, and printed material, could revolutionize personalized medicine. Scientists are investigating ways to functionalize galactomannans with bioactive molecules to enhance their biological performance. This is the first review of galactomannans that combines their chemical modifications with biological activities, presenting various biomaterial possibilities with a focus on biomedical applications. The rising demand for renewable-source materials in the medical field underscores their importance, driving ongoing research to explore their full capabilities. As studies progress, the scope of clinical applications for galactomannan-based materials is expected to broaden. To maximize the bioactive potential of galactomannan-based materials, emphasis should be placed on clinical translation to facilitate its effective incorporation into biomedical applications.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"311 ","pages":"Article 143614"},"PeriodicalIF":7.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143891000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainable polyhydroxybutyrate (PHB) production from biowastes by Halomonas sp. WZQ-1 under non-sterile conditions","authors":"Ziqian Wang,&nbsp;Chunyu Du,&nbsp;Ruyu Yan,&nbsp;Shuying Li,&nbsp;Guanyu Zheng,&nbsp;Dahu Ding","doi":"10.1016/j.ijbiomac.2025.143643","DOIUrl":"10.1016/j.ijbiomac.2025.143643","url":null,"abstract":"<div><div>Polyhydroxyalkanoates (PHA) are promising candidates for replacing petroleum-derived plastics; however, their high production costs limit their commercialisation. In this study, we successfully isolated an efficient PHA-producing strain from a salt lake, which was subsequently identified as <em>Halomonas</em> sp. WZQ-1. Notably, <em>Halomonas</em> sp. WZQ-1 could serve as a promising cell-factory platform for polyhydroxybutyrate (PHB) production, achieving a comparatively high PHB productivity (7.64 ± 0.4 g L⁻¹) under moderate salt stress (60 g L⁻¹ NaCl). We further realised semi-continuous PHB production in a bench-scale fermenter at a steady state by irregularly replenishing the organic substrate. The maximum PHB concentration reached 12.13 g L⁻¹. Finally, we realised the non-sterile conversion of typical biowastes (e.g. pomelo and cantaloupe residues) to PHB using <em>Halomonas</em> sp. WZQ-1. Encouragingly, 4.36 g L⁻¹ PHB was directly obtained from the hydrolysate of pomelo residues with a characteristic melting temperature of 174.0 °C. Life cycle assessment was employed to systematically evaluate the environmental sustainability and potential challenges of biowaste-driven PHB biorefineries. Overall, our findings could serve as a pivotal step toward the commercialisation of PHB and provide a valuable reference for PHB biorefineries.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"311 ","pages":"Article 143643"},"PeriodicalIF":7.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143895326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NAE1 protein: a prognostic, immunomodulatory, and therapeutic biomarker associated with neddylation in hepatocellular carcinoma","authors":"Yong Pan,&nbsp;Jinyao Dai,&nbsp;Yi Liu,&nbsp;Yujing Wang,&nbsp;Qiudan Zhang,&nbsp;Yan Lou,&nbsp;Yunqing Qiu","doi":"10.1016/j.ijbiomac.2025.143539","DOIUrl":"10.1016/j.ijbiomac.2025.143539","url":null,"abstract":"<div><div>Current predictive biomarkers for clinical outcomes and treatment in hepatocellular carcinoma (HCC) are not reliable enough. Neddylation, a novel post-translational modification, plays a crucial role in the immunomodulation, metabolism, and pathogenesis of HCC. However, whether it can function as a powerful predictive biomarker for HCC remains unknown. In current research, we first identified NAE1 as the most significant neddylation-related gene affecting the prognosis of HCC patients mainly through weighted gene co-expression network (WGCNA) and machine learning. Subsequently, we determined NAE1 expression as an independent risk factor for HCC using univariate and multivariate Cox regression and constructed a nomogram integrating NAE1 expression with clinical characteristics to predict survival probabilities in HCC patients. Bulk and single-cell RNA sequencing analyses revealed that NAE1 expression was primarily positively connected with immune cell infiltration in HCC, as assessed by the six latest immune algorithms. In addition, drug sensitivity and molecular docking collectively revealed the influence of NAE1 expression on the IC50 values of the four agents and the binding interactions between NAE1 protein and these drugs. Furthermore, we found that NAE1 depletion suppressed proliferation, migration, and invasion of HCC cells in vitro experiments. In conclusion, NAE1 protein holds considerable potential as a valuable biomarker for predicting clinical outcomes, immune landscapes, and drug sensitivity in HCC, as well as a promising therapeutic target.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"310 ","pages":"Article 143539"},"PeriodicalIF":7.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143879148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cellulose-based aerogels for efficient dye sorption and oil-water separation in textile wastewater treatment","authors":"Jie Chen,&nbsp;Jialing Chen,&nbsp;Laijiu Zheng,&nbsp;Huanda Zheng","doi":"10.1016/j.ijbiomac.2025.143612","DOIUrl":"10.1016/j.ijbiomac.2025.143612","url":null,"abstract":"<div><div>The increasing environmental pollution resulting from wastewater generated by the textile industry, which is often contaminated with non-biodegradable dyes and oils, underscores the urgent need for innovative treatment solutions. In this work, we introduce a novel bacterial cellulose (BC)-based aerogel, enhanced with sodium carboxymethyl cellulose (CMC) and polydimethylsiloxane (PDMS), designed for effective dye sorption and oil-water separation. The CMC/BC and PDMS/CMC/BC aerogels, fabricated through a straightforward mixing and freeze-drying process, exhibiting a high porosity of 96 %, a low density of 0.097 g/cm³, and remarkable mechanical strength with a compressive stress of 0.70 MPa at 80 % strain. The CMC/BC aerogel exhibited an exceptional dye sorption capacity of 484 mg/g, achieving a maximum removal rate of 96.80 % within 12 h. This performance aligns closely with the pseudo-second-order kinetic model and the Langmuir isothermal model, suggesting that the sorption process is controlled by chemisorption and occurs as a monolayer. Additionally, the PDMS/CMC/BC-11 aerogel exhibited remarkable oil sorption efficiency, attaining 186.03 g/g for petroleum ether, and effectively separated oil from water within 5 s. These findings highlight the potential of the composite aerogels for applications in environmental remediation and industrial processes.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"310 ","pages":"Article 143612"},"PeriodicalIF":7.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143881786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green fabrication of highly flame-retardant, anti-ultraviolet radiation and superhydrophobic cellulose-based fabric by constructing dualtielement-containing NH2-MIL-53(Al)@Triethoxyoctylsilane nano coatings","authors":"Jiang Chang ,&nbsp;Ying Qin ,&nbsp;Weimin Guo,&nbsp;Jingyuan Zhang,&nbsp;Kuo Zhang,&nbsp;Jianhua Zheng,&nbsp;Lijian Sun,&nbsp;Qiu Fu","doi":"10.1016/j.ijbiomac.2025.143560","DOIUrl":"10.1016/j.ijbiomac.2025.143560","url":null,"abstract":"<div><div>The facile and eco-friendly fabrication of a fabric with remarkable flame retardancy, anti-ultraviolet (UV), and superhydrophobic properties is of significant interest for multitask requirements. In this regard, herein, a nonfluorine, facile, and green method is reported for in situ synthesis of metal-organic frame (NH₂-MIL-53(Al)) on hemp fabric (HF) for the preparation of multifunctional textiles. A homogeneous and compact coating of NH₂-MIL-53(Al) crystals was deposited on HF, followed by modification with triethoxyoctylsilane (TEOS) to manufacture superhydrophobic NH₂-MIL-53(Al)@hemp fabric (SM(Al)HF-9), significantly enhancing its water stability. The SM(Al)HF-9 exhibited superior superhydrophobicity properties, with a water contact angle (WCA) up to 156°. Furthermore, the surface of SM(Al)HF-9 cannot be adhered by dye solution and powder, indicating its good self-cleaning and anti-fouling abilities. The SM(Al)HF-9, characterized by a porous structure, effectively separates tetrachloromethane and n-hexane from water mixtures with a separation efficiency exceeding 97 %. The SM(Al)HF-9 has excellent UV-blocking properties, and the UV protection factor is as high as 105.44. Encouragingly, the SM(Al)HF-9 exhibited outstanding flame retardancy, as demonstrated by its self-extinguishing capability and a substantially improved limiting oxygen index (LOI) of 32.4 %. In comparison to raw HF, the peak heat release rate (PHRR) and total heat rate (THR) of the modified HF are reduced by 76.15 % and 54.32 %, respectively. Meanwhile, the NH₂-MIL-53(Al) has a significant advantage over other MOFs (e.g., ZIF-67, Ce-MOF, Ag-MOF, Fe-MOF and MIL-53(Al)) in improving the flame retardancy of HF. The highly efficient flame-retardant, anti-UV, and superhydrophobic fabric is promising in home and public decoration, and fire protection fields.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"310 ","pages":"Article 143560"},"PeriodicalIF":7.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143881793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation, characterization and analysis of anthocyanin arbutin co-amorphous complexes and evaluation of the inhibition of tyrosinase","authors":"Ke-han Qiu ,&nbsp;Yu-jie Wang ,&nbsp;Kai-li Cheng ,&nbsp;Le-qi Jiang ,&nbsp;Xuan Li ,&nbsp;Jiu-liang Zhang","doi":"10.1016/j.ijbiomac.2025.143600","DOIUrl":"10.1016/j.ijbiomac.2025.143600","url":null,"abstract":"<div><div>Natural phenolic compounds, such as anthocyanins and arbutin, have demonstrated significant potential as tyrosinase (TYR) inhibitors. However, the application of anthocyanins in biological systems is hindered by their instability under alkaline conditions, elevated temperatures, and light exposure. In contrast, arbutin exhibits superior stability while also functioning as a TYR inhibitor. To overcome these limitations, this study developed an Anthocyanin-α-Arbutin Co-amorphous (AAC) system aimed at enhancing both the stability of anthocyanins and their TYR inhibitory properties. Kinetic studies revealed that anthocyanins, arbutin, and AAC act as reversible mixed-type TYR inhibitors, with competitive inhibition as the predominant mechanism. Each compound exhibited distinct inhibition sites. Fluorescence analysis demonstrated that anthocyanins induce a fluorescence burst in TYR, likely attributed to Tyr residues, whereas α-arbutin and AAC enhance the fluorescence intensity of TYR. Moreover, α-arbutin and AAC were found to decrease the microenvironmental hydrophobicity surrounding tyrosine (Tyr) residues while increasing it around tryptophan (Trp) residues, suggesting potential conformational changes in tyrosinase. Molecular docking analysis indicated that hydrogen bonding and π-π stacking interactions occurred between anthocyanins and arbutin in the AAC system. Specifically, anthocyanins primarily interacted with TYR through π-π and π-alkyl interactions, while α-arbutin predominantly bound to TYR via hydrogen bonding. Consistent with the interaction study, α-arbutin was found to associate with tyrosinase mainly through hydrogen bonding and van der Waals forces. These findings provide novel insights into the interactions between anthocyanins and α-arbutin in the context of food science and lay a foundation for the development of innovative TYR inhibitors.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"311 ","pages":"Article 143600"},"PeriodicalIF":7.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143885883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly sensitive and multifunctional Fe3+ enhanced PVA/gelatin multi-network hydrogels with wide temperature range environmental stability for wearable sensors","authors":"Ying Wang ,&nbsp;Yuchen Zhang ,&nbsp;Hui Lv ,&nbsp;Xiang Fang ,&nbsp;Bencai Lin ,&nbsp;Guanggui Cheng ,&nbsp;Ningyi Yuan ,&nbsp;Jianning Ding","doi":"10.1016/j.ijbiomac.2025.143606","DOIUrl":"10.1016/j.ijbiomac.2025.143606","url":null,"abstract":"<div><div>Hydrogels are one of the ideal materials for preparing new flexible sensor devices. In this work, based on the freeze-thaw cycle and Hoffmeister effect to improve the mechanical properties, a low-temperature resistant multifunctional conductive hydrogel with excellent mechanical properties, high transparency, high adhesion, high conductivity, high sensitivity, excellent sensing ability and self-healing ability was prepared by diffusing Fe³⁺ and ethylene glycol (EG) in the hydrogel network via immersion method. Moreover, wearable sensors assembled from it could accurately monitor the movement of various parts of the human body, and it could accurately identify tiny strain and pressure sensing. In addition, the hydrogel had long-term stability (after 7 days at room temperature, it still maintained 88.03 % of its original weight), strong adhesion (after repeated adhesion for 3 times, the adhesion to 6 materials was more than 72 % of the original value), excellent frost resistance (not freeze under −50 °C), and good self-repairing ability (the cut hydrogel would be self-repaired after 5 min and could be stretched to more than 2 times the original length). The hydrogel's multifunctionality and high sensitivity to small strains will make it show a high application prospect in the field of precision sensing.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"311 ","pages":"Article 143606"},"PeriodicalIF":7.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143890852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}