International Journal of Biological Macromolecules最新文献

{"title":"Recent advance on the antibacterial activity of polysaccharide-based conjugates","authors":"Shiwei Li ,&nbsp;Ziyan Zhao ,&nbsp;Yingna Wang ,&nbsp;Beibei He ,&nbsp;Keshi Ma ,&nbsp;Yi Zheng ,&nbsp;Mulian Wang ,&nbsp;Zichao Wang ,&nbsp;Lili Li","doi":"10.1016/j.ijbiomac.2025.144760","DOIUrl":"10.1016/j.ijbiomac.2025.144760","url":null,"abstract":"<div><div>Polysaccharide has attracted global attention because of its potential application as an alternative to antibiotics to alleviate antibiotic resistance and drug residue caused by antibiotic abuse, but its relatively low antibacterial activity and narrow antibacterial spectrum cannot meet the needs of daily life and clinical treatment. Apart from chemical, physical, and biological modifications, conjugation with other bioactive compounds via covalent or non-covalent interactions can not only improve the antibacterial activity and reduce the bacterial resistance of polysaccharide-based conjugates, but also expand the antibacterial spectrum and reduce the cytotoxicity of polysaccharide-based conjugates. Then, a systematic and up-to-date overview of the conjugation strategies aimed at enhancing the antibacterial activity of polysaccharides will guide the future development of polysaccharide conjugates with enhanced antibacterial properties. Therefore, in this study, the conjugation of polysaccharides with protein, polyphenol, essential oil, organic acid, polyvinyl, antibiotic, and other bioactive compounds was investigated to improve the antibacterial activity of polysaccharide-based conjugates, thereby demonstrating the potential action mechanism of polysaccharide-based conjugate. Meanwhile, existing problems and future prospects for the development and application of polysaccharide-based conjugates with good antibacterial activities are suggested. This study could provide guidance for adopting conjugation to improve the antibacterial activity and application of polysaccharides.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"316 ","pages":"Article 144760"},"PeriodicalIF":7.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adsorptive removal of methylene blue dye onto sodium alginate/polythiophene composite microbeads: Non-linear isotherm, kinetic, and thermodynamic study","authors":"Miray Eylul Berk,&nbsp;Birol Isik,&nbsp;Volkan Ugraskan,&nbsp;Ozlem Cankurtaran","doi":"10.1016/j.ijbiomac.2025.144757","DOIUrl":"10.1016/j.ijbiomac.2025.144757","url":null,"abstract":"<div><div>Polythiophene (PTh), a class of conductive polymers, has the potential to be an effective adsorbent due to its tunable characteristics, environmental stability, electron-rich structure, and so on. Though its efficiency has been proven in many applications, investigations into using PTh in adsorption studies are currently lacking. For the first time, this study examined the efficiency of sodium alginate (SA) matrix composites filled with PTh for dye removal by adsorption. First, PTh was synthesized using the oxidative chemical polymerization process, and SA composites with PTh in different weight ratios were produced. Methylene blue (MB), one of the most used dyes in the industry, was chosen as a model dye for adsorption studies. Adsorption experiments revealed that the best composite composition is 10 % PTh (SA-PTh-10), with optimal temperature = 298 K, pH = 6, contact time = 90 min, and adsorbent amount = 0.025 g/50 mL. The MB dye adsorption process was carried out using a pseudo-second-order kinetic model with non-linear regression coefficients (<span><math><msup><mi>r</mi><mn>2</mn></msup><mo>=</mo><mn>0.9999</mn></math></span>). The non-linear Langmuir adsorption isotherm model is consistent with MB dye adsorption, indicating monolayer adsorption on the composite. According to the Langmuir adsorption isotherm model calculations, SA-PTh-10 microbeads have a maximum adsorption capacity of 134.32 mg/g. Furthermore, the Sips isotherm model shows that SA-PTh-10 composite microbeads have a high adsorption capacity of 104.37 mg/g. Exothermic and spontaneous adsorption of MB dye was revealed by the negative enthalpy (<span><math><mo>∆</mo><msup><mi>H</mi><mi>o</mi></msup><mo>=</mo><mo>−</mo><mn>20.13</mn></math></span> kJ/mol) and Gibbs free energy (<span><math><mo>∆</mo><msup><mi>G</mi><mi>o</mi></msup><mo>=</mo><mo>−</mo><mn>25.75</mn></math></span> kJ/mol). Reusability study was conducted, and composite microbeads were observed to be effective for up to 7 cycles.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"316 ","pages":"Article 144757"},"PeriodicalIF":7.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The interaction of the biocompatible scaffold containing nanochitosan-chitosan-polycaprolactone with telomerase activator and rock inhibitor in propagation and functional properties of corneal endothelial cells","authors":"Tahereh Tayebi ,&nbsp;Mohammadreza Kasravi ,&nbsp;Ali Naderi ,&nbsp;Bahram Jambar Nooshin ,&nbsp;Hassan Niknejad","doi":"10.1016/j.ijbiomac.2025.144744","DOIUrl":"10.1016/j.ijbiomac.2025.144744","url":null,"abstract":"<div><h3>Background</h3><div>Corneal endothelial disfunction, which is results from the injury or loss of corneal endothelial cells (CECs), is the major cause of corneal opacity and visual impairment. Corneal transplantation is the only therapeutic choice for endothelium deficiency, but global donor shortage has posed a serious challenge worldwide. Alternative treatments, especially regenerative medicine strategies including cell therapy and tissue engineering, can overcome this limitation. Hence, the aim of this study is the construction of transplantable grafts carrying functional CECs.</div></div><div><h3>Methods</h3><div>We fabricated and characterized scaffold containing chitosan nanoparticles, chitosan and polycaprolactone. HCECs were isolated from corneal endothelium and cultured on the fabricated scaffold. Cell proliferation was induced using the telomerase activator and ROCK inhibitor. Functional characteristics of the HCECs and cell-scaffold interactions were evaluated via evaluation of gene expression, flow cytometry, electron microscopy and MTT assay.</div></div><div><h3>Results</h3><div>The results showed that fabricated scaffold had a suitable transparency and grate biocompatibility. &gt;98 % of the isolated cells had the CD166⁺/CD98⁺ phenotype. Telomerase activator and ROCK inhibitor increased the proliferation of HCECs by 1.5 and 2.3 times, respectively, and the simultaneous use synergistically increased the cell proliferation by 4.3 times. Culture of HCECs on scaffolds significantly increased their proliferation. Cell count, SEM images and H&amp;E results showed proper cell-surface interaction with the formation of a cell monolayer on the scaffold. Flow cytometry results showed that &gt;97 % of the cells cultured on scaffold maintained their CD166⁺/CD44⁻ phenotype.</div></div><div><h3>Conclusions</h3><div>According to the results, the designed scaffold and telomerase activator and ROCK inhibitor had the synergistic effects on cultured HCECs behaviors such as cell adhesion, proliferation and phenotypic maintenance, which is powerful evidence for application of this scaffold as a suitable carrier for HCECs transplantation.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"316 ","pages":"Article 144744"},"PeriodicalIF":7.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integration of transcriptome analysis and protein verification reveals that melatonin facilitates postharvest storage quality of pitaya fruit via HpRING1-HpSOD2 ubiquitination module mediated reactive oxygen species scavenging","authors":"Jiaxiang Liu ,&nbsp;Weiping Mo ,&nbsp;Kun Xiao ,&nbsp;Tingting Yan ,&nbsp;Liu Shao ,&nbsp;Shuqin Chen ,&nbsp;Tianyu Li ,&nbsp;Xinjie Yao ,&nbsp;Xiaolong Zhou ,&nbsp;Yongqing He ,&nbsp;Yutong Ju ,&nbsp;Jiaqi Yan ,&nbsp;Lin Wang","doi":"10.1016/j.ijbiomac.2025.144764","DOIUrl":"10.1016/j.ijbiomac.2025.144764","url":null,"abstract":"","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"316 ","pages":"Article 144764"},"PeriodicalIF":7.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144185296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A pectic polysaccharide from wax gourd peel improves ethanol-induced gastric ulcer injury in mice via the PI3K/AKT signaling pathway","authors":"Bi Luo ,&nbsp;Mangui Cai ,&nbsp;Hongyang Huang ,&nbsp;Yiheng Zhang ,&nbsp;Peng Chen ,&nbsp;Ruifeng Ji ,&nbsp;Feng Wang ,&nbsp;Peiran Liao ,&nbsp;Minghua Xian","doi":"10.1016/j.ijbiomac.2025.144755","DOIUrl":"10.1016/j.ijbiomac.2025.144755","url":null,"abstract":"<div><div>The pectic polysaccharide WGPP-1a (46.8 kDa) has been obtained from wax gourd peel (WGP) which is a popular soup ingredient and Chinese herbal medicines in China. Monosaccharide composition, methylation analysis, FT-IR and NMR demonstrate that WGPP-1a is composed of rhamnogalacturonan I (RG-I) and homogalacturonan (HG) domains with mass ratios of 4:1. The RG-I domains contain a highly branched structure that is substituted primarily with β-D-1,4-galactan, α-L-1,5-arabinan and β-D-1,4-glucan. In ethanol-induced gastric ulcer mice, WGPP-1a reduced ulcer area, restored mucosal glycoproteins. In vitro, WGPP-1a enhanced GES-1 cell viability and reduced apoptosis. Untargeted LC-MS metabolomics of murine gastric tissues revealed 322 differential metabolites (163 upregulated, 159 downregulated) between Model and control groups, with WGPP-1a treatment restoring 120 metabolites (53 upregulated, 67 downregulated). PCA and OPLS-DA demonstrated WGPP-1a's reversal of ethanol-induced perturbations. KEGG pathway enrichment identified eight core pathways modulated by WGPP-1a, including PI3K/AKT signaling, Linoleic acid metabolism, and mTOR/FoxO pathways. Notably, Mechanistically, WGPP-1a activated the PI3K/AKT pathway, elevating Bcl-2/Bax ratios and suppressing the expression levels of pro-apoptotic proteins Bax and Caspase3. These results suggest that WGPP-1a may be an effective agent for protecting against alcoholic gastric ulcers and provides a new perspective for the resource utilization of WGP.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"316 ","pages":"Article 144755"},"PeriodicalIF":7.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparation of polyethylene grafted cellulose for the removal of diethyl phthalate from wastewater","authors":"Sarah Alharthi ,&nbsp;Syeda Rida Shah ,&nbsp;Nimra Kanwal ,&nbsp;Aqsa Tasleem ,&nbsp;Tahira Bibi ,&nbsp;Eman Y. Santali ,&nbsp;Ashraf Ali","doi":"10.1016/j.ijbiomac.2025.144717","DOIUrl":"10.1016/j.ijbiomac.2025.144717","url":null,"abstract":"<div><div>A novel polyethylene glycol (PEG)-functionalized cellulose adsorbent (PEG-Cell) derived from sawdust was developed for the efficient removal of diethyl phthalate (DEP) from wastewater. The synthesis involved sequential acid (0.1 M HCl) and alkaline (0.1 M NaOH) hydrolysis of sawdust, followed by sodium chlorate bleaching and PEG grafting to introduce hydrophilic glycol groups onto the cellulose matrix. The PEG-Cell adsorbent demonstrated exceptional DEP removal performance at optimized conditions: initial DEP concentration (100 mg/L), adsorbent dose (0.6 g/L), contact time (60 min), and pH (7) achieving 97.5% removal efficiency and a remarkable adsorption capacity of 512.46 mg/g. Equilibrium studies revealed that the adsorption process followed the Langmuir isotherm model, suggesting monolayer coverage and strong chemical interactions between DEP molecules and PEG-Cell’s functionalized surface. Kinetic study indicated that the adsorption adhered to the pseudo-second-order model, confirming chemisorption as the dominant mechanism. Thermodynamic investigations further supported the process’s feasibility, with negative ΔG° values (−8.3 kJ/mol) indicating spontaneity, while positive ΔH° (45.3 kJ/mol) and ΔS° (0.18 kJ/mol·K) values suggested an endothermic and entropy-driven process. The adsorbent exhibited excellent reusability, maintaining high efficiency (&gt;90%) over multiple regeneration cycles with minimal capacity loss. These findings highlight PEG-Cell as a cost-effective, sustainable, and highly efficient adsorbent for removing DEP and other phthalates from contaminated water sources, offering significant potential for scalable wastewater treatment applications.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"316 ","pages":"Article 144717"},"PeriodicalIF":7.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Porous bioactive chitosan-based catalyst via UV-grafting ice-templated and self-reduction approaches for effective hydrogenation reduction of azo dye","authors":"Abdul Haleem ,&nbsp;Xianshuang Zhu ,&nbsp;Dost Muhammad Khan ,&nbsp;Buriro Ghous Bakhsh ,&nbsp;Kaixuan Huang ,&nbsp;Hao Li ,&nbsp;Hua Zhong","doi":"10.1016/j.ijbiomac.2025.144543","DOIUrl":"10.1016/j.ijbiomac.2025.144543","url":null,"abstract":"<div><div>Bio-based porous materials have attracted significant attention over recent decades as environmentally sustainable alternatives to synthetic counterparts. This study synthesized a three-dimensional porous biocatalyst through UV-assisted cryopolymerization to graft acrylamide onto chitosan chains, followed by in situ integration of silver nanoparticles via a self-reduction mechanism. The composite exhibited enhanced antibacterial efficacy against <em>Escherichia coli</em> (<em>E. coli</em>), attributable to the synergistic effects of chitosan and silver nanoparticles. A rapid swelling ratio (20 s) corroborated the macroporous architecture of the material. The biocatalyst demonstrated exceptional catalytic performance in the hydrogenation reduction of Congo red azo dye under both deionized and tap water conditions when paired with a reducing agent. Notably, formulations with lower chitosan content achieved superior reduction kinetics, yielding apparent rate constants of 0.160 min⁻¹ and 0.117 min⁻¹ in deionized water and tap water, respectively. Key structural advantages such as tunable porosity, hydrophilicity, biodegradability, and an economical fabrication protocol collectively contributed to its enhanced catalytic efficiency. Critical operational parameters such as biocatalyst dosage and temperature were systematically evaluated to assess scalability potential. Thermodynamic analysis via the Arrhenius equation revealed an activation energy (Eₐ) of 35.45 kJ.mol⁻¹ for Congo red hydrogenation. Complementary Eyring equation calculations provided enthalpy (ΔH = −33.67 kJ.mol⁻¹) and entropy (ΔS = −159.15 J.mol⁻¹.K⁻¹), consistent with an associative reaction mechanism. The biocatalyst maintained robust reusability over four consecutive cycles with negligible change in hydrogenation reduction performance. Collectively, this work establishes a green, high-performance biocatalytic platform with superior environmental compatibility compared to conventional synthetic catalysts, underscoring its potential for sustainable wastewater treatment applications.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"316 ","pages":"Article 144543"},"PeriodicalIF":7.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High internal phase emulsions stabilized with whey protein microgels: Characterization, physical stability, and liquid smoke encapsulation efficiency","authors":"Siqi Zhao,&nbsp;Mengtong Li,&nbsp;Xinyao Xu,&nbsp;Qian Chen,&nbsp;Haotian Liu,&nbsp;Hongbo Sun","doi":"10.1016/j.ijbiomac.2025.144605","DOIUrl":"10.1016/j.ijbiomac.2025.144605","url":null,"abstract":"<div><div>A whey protein microgel (WPM) was formed by heating whey protein isolate (WPI) at 90 °C for 30 min and the characteristics of the former were then analyzed. The findings showed that the WPM droplet size and surface net charge were significantly larger than those of the WPI. Fluorescence spectroscopy and Fourier transform infrared (FTIR) spectra revealed that the WPI unfolded in response to heating. The WPM suspension was adjusted to concentrations of 1 %, 2 %, 3 %, 4 %, and 5 % (w/v) and used to stabilize high internal phase emulsions (HIPEs) embedding liquid smoke. The droplet sizes of the HIPE decreased and its rheological behavior and physical stability increased with increasing WPM concentration. Gas chromatography-mass spectrometry (GC–MS) disclosed that the rate of retention of the volatile flavor compounds in the liquid smoke increased with WPM concentration. Overall, the HIPEs fabricated herein could potentially be used for the encapsulation and sustained release of active flavoring in the food industry.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"316 ","pages":"Article 144605"},"PeriodicalIF":7.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Starch films with triethanolamine and chalcone derivative for improved durability and antimicrobial properties in poultry packaging","authors":"S.P. Ramya Ranjan Nayak ,&nbsp;Pratik Pohokar ,&nbsp;L.S. Dhivya ,&nbsp;Aveeda Herold ,&nbsp;V. Chitra ,&nbsp;Mansour K. Gatasheh ,&nbsp;Selvaraj Arokiyaraj ,&nbsp;Kathiravan Muthu Kumaradoss ,&nbsp;Jesu Arockiaraj","doi":"10.1016/j.ijbiomac.2025.144627","DOIUrl":"10.1016/j.ijbiomac.2025.144627","url":null,"abstract":"<div><div>This study focuses on the use of Triethanolamine (TEA) as a plasticizer to improve the mechanical and physical properties of starch films, while also incorporating the chalcone derivative, DKO1 ((2E)-1-(5-methylfuran-2-yl)-3-(4-nitrophenyl) prop-2-en-1-one) to provide antimicrobial activity. The addition of TEA at 4 % significantly improved the films' mechanical strength (&gt;5 MPa), microstructure, and moisture barrier (&lt;20 g⁻¹ h⁻¹) properties by promoting cross-linking, resulting in a flexible and long-lasting packaging material. The addition of DKO1 at 80 μM concentration increased antimicrobial activity against food pathogens <em>Salmonella typhi</em> and <em>Listeria monocytogenes</em>. The films also demonstrated increased hydrophobicity (53.6γ_s) and biodegradability in soil (&gt;60 %), providing an environmentally friendly end-of-life option. DKO1-loaded films effectively reduced spoilage microorganisms and prevented meat spoilage (&lt;8 CFU/g), as evidenced by biochemical and proximate analyses of poultry meat. Biogenic amine quantification revealed a reduction in cadaverine (&lt;15 mg/kg) and putrescine (&lt;90 mg/kg) production in meat stored with DKO1 films, indicating improved preservation. Furthermore, these active films maintained the meat's sensory qualities, which corresponded to consumer preferences (&gt;5 points). This edible and bioactive film offers a sustainable alternative to plastic packaging, with a lower carbon footprint than petroleum-based materials.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"316 ","pages":"Article 144627"},"PeriodicalIF":7.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From sugarcane bagasse pulp into electroactive materials: Carboxymethyl cellulose/reduced graphene oxide/nickel oxide composites as high-performance supercapacitor components","authors":"Mohamed A. Abdelfadeel ,&nbsp;Sherief A. Al Kiey ,&nbsp;Peter Hesemann ,&nbsp;Ahmad Mehdi ,&nbsp;Samir Kamel ,&nbsp;Ahmed K. El-Ziaty ,&nbsp;Naglaa Salem El-Sayed","doi":"10.1016/j.ijbiomac.2025.144703","DOIUrl":"10.1016/j.ijbiomac.2025.144703","url":null,"abstract":"<div><div>We report bio-sourced electrically conductive materials derived from sugarcane bagasse cellulose. First, the cellulose was chemically transformed into carboxymethyl cellulose (CMC). Acrylamide (AM) and 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS) were <em>co</em>-polymerized with CMC, and the resulting material was cross-linked with <em>N,N`</em>-methylenebisacrylamide (MBA) to improve its mechanical properties. To further enhance the electrical performance, the materials were modified with reduced graphene oxide (rGO), nickel oxide (NiO) nanoparticles and rGO@NiO composites. The nanocomposites were then used as electrodes for solid-state supercapacitors. To evaluate the electrochemical properties of these materials, cyclic voltammetry (CV), galvanostatic charge-discharge (GCD), and electrochemical impedance spectroscopy (EIS) were performed. These results demonstrate enhanced electrochemical performance of the composite material modified with both rGO and NiO NPs. CV profiles exhibited well-defined redox peaks indicative of reversible faradaic processes, confirming high pseudocapacitance contributions. The optimized sample X_GNi2.5 exhibited a high specific capacitance of 497.8 F g⁻¹ at 0.5 A g⁻¹, outstanding cycling stability with 91 % capacitance retention after 5000 cycles, and a maximum energy density of 44.2 Wh kg⁻¹ at a power density of 226.2 W kg⁻¹. EIS revealed low charge transfer resistance and efficient ion transport. These results underscore the potential of CMC/rGO/NiO composites as sustainable, high-performance electrode materials for next-generation supercapacitors.</div></div>","PeriodicalId":333,"journal":{"name":"International Journal of Biological Macromolecules","volume":"316 ","pages":"Article 144703"},"PeriodicalIF":7.7,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}