Therapeutic Advances in Vaccines and Immunotherapy最新文献

筛选
英文 中文
Comparative 60-day effectiveness of bivalent versus monovalent mRNA vaccines in Shelby County: a population-level analysis. 谢尔比县二价与单价 mRNA 疫苗的 60 天效果比较:人群水平分析。
Therapeutic Advances in Vaccines and Immunotherapy Pub Date : 2024-09-19 eCollection Date: 2024-01-01 DOI: 10.1177/25151355241278852
Allison P Plaxco, Jennifer Kmet, Matthew P Smeltzer, Yu Jiang, Michelle Taylor, Vikki G Nolan
{"title":"Comparative 60-day effectiveness of bivalent versus monovalent mRNA vaccines in Shelby County: a population-level analysis.","authors":"Allison P Plaxco, Jennifer Kmet, Matthew P Smeltzer, Yu Jiang, Michelle Taylor, Vikki G Nolan","doi":"10.1177/25151355241278852","DOIUrl":"10.1177/25151355241278852","url":null,"abstract":"<p><strong>Background: </strong>Two monovalent mRNA vaccines, available in December 2020, were demonstrated to have high efficacy against both the original SARS-CoV-2 strain and variants circulating through the summer and into the fall of 2021. In the context of the Omicron/BA.1 variant, which was predominant from late fall 2021 into winter of 2022 in the United States, and subsequent Omicron subvariants that have been predominant thereafter, vaccine effectiveness of the monovalent mRNA vaccine option is attenuated.</p><p><strong>Objectives: </strong>We aim to investigate the relative effectiveness of the bivalent booster compared to the monovalent booster against SARS-CoV-2 infection in the 60 days following administration in Shelby County, TN.</p><p><strong>Design: </strong>This observational population-based cohort study utilizes COVID-19 surveillance data to identify adults who were vaccinated with a monovalent booster dose between August 1, 2022 and August 30, 2022 or a bivalent booster dose between September 1, 2022 and September 30, 2022. Both groups were followed for COVID-19 status for 60 days from their administration date.</p><p><strong>Methods: </strong>We calculated incidence rates with 95% confidence intervals and propensity-adjusted hazard ratios with 95% confidence intervals of COVID-19 diagnosis in the 60 days following administration of the booster dose between the bivalent group and the monovalent group. Stratified analysis was conducted by age group (18-34, 35-64, and 65+ years old).</p><p><strong>Results: </strong>The incidence of reported SARS-CoV-2 infection was substantially higher for those who received the monovalent booster, across age groups. Overall, we observed a 51% lower hazard of infection during the study period among those who received the bivalent booster, compared to the monovalent booster.</p><p><strong>Conclusion: </strong>These results support and extend prior findings that the bivalent booster dose may be more effective in preventing infection against the Omicron sub-variants of SARS-CoV-2.</p>","PeriodicalId":33285,"journal":{"name":"Therapeutic Advances in Vaccines and Immunotherapy","volume":"12 ","pages":"25151355241278852"},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11418355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142308681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vaccination practices and knowledge among adults with hemoglobinopathies in Greece: a nationwide survey. 希腊成年血红蛋白病患者的疫苗接种习惯和知识:一项全国性调查。
Therapeutic Advances in Vaccines and Immunotherapy Pub Date : 2024-09-17 eCollection Date: 2024-01-01 DOI: 10.1177/25151355241278869
Sophia Delicou, Konstantinos Manganas, Aikaterini Xydaki, Loukia Evliati, Ioanna Myrilla, Leonidas Rubatis, Stavroula Kostaridou
{"title":"Vaccination practices and knowledge among adults with hemoglobinopathies in Greece: a nationwide survey.","authors":"Sophia Delicou, Konstantinos Manganas, Aikaterini Xydaki, Loukia Evliati, Ioanna Myrilla, Leonidas Rubatis, Stavroula Kostaridou","doi":"10.1177/25151355241278869","DOIUrl":"10.1177/25151355241278869","url":null,"abstract":"<p><strong>Background: </strong>Hemoglobinopathies, such as sickle cell disease and thalassemia, are genetic disorders that affect hemoglobin structure or production, leading to various health complications, including an increased risk of infections. Vaccinations play a crucial role in managing these conditions by providing essential protection against preventable diseases. Ensuring timely and appropriate immunizations is vital for reducing infection-related morbidity and improving the overall health and quality of life for affected individuals.</p><p><strong>Objectives: </strong>Our objective was to assess vaccination coverage, as well as knowledge, attitudes, and practices toward vaccination in Greek patients with hemoglobinopathies.</p><p><strong>Design and methods: </strong>A nationwide survey of hemoglobinopathy patients in Greece using a 37-item questionnaire was conducted anonymously via Google Forms. It covered demographics, previous vaccinations, vaccine-preventable infections, beliefs about vaccines, and antibiotic prophylaxis post-splenectomy. The survey was distributed through Thalassemia and Sickle Cell Units and organizations.</p><p><strong>Results: </strong>Participants were predominantly university-educated married women aged 30-50 years with transfusion-depended thalassemia (<i>n</i> = 149, 60.5%) or sickle cell anemia (<i>n</i> = 52, 21.1%). Reported childhood vaccination rates aligned with Greece's national immunization program. However, adult coverage was suboptimal across all age groups for measles (10%), varicella (27%), zoster (2% for over 50 years old individuals), hepatitis A (13.9% of those with chronic liver disease) and hepatitis B (41%), pneumococcal (81.3%), meningococcal (37%), tetanus (20.3%), and influenza (67.1%) vaccines compared to guidelines. Participants relied predominantly on healthcare providers for vaccine information but perceived limited engagement. Those over age 50 demonstrated lower adult vaccination rates and higher misconceptions compared to younger cohorts.</p><p><strong>Conclusion: </strong>Addressing educational and access gaps could help protect this vulnerable population. Our findings highlight the need for coordinated efforts to optimize adult immunization for those with hemoglobinopathies.</p>","PeriodicalId":33285,"journal":{"name":"Therapeutic Advances in Vaccines and Immunotherapy","volume":"12 ","pages":"25151355241278869"},"PeriodicalIF":0.0,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11418312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142308682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Media literacy: exploring the key to social media influences for wise parental decision-making on vaccines. 媒体素养:探索社交媒体影响的关键,让家长明智地做出疫苗决策。
Therapeutic Advances in Vaccines and Immunotherapy Pub Date : 2024-09-12 eCollection Date: 2024-01-01 DOI: 10.1177/25151355241277780
Dalmacito A Cordero
{"title":"Media literacy: exploring the key to social media influences for wise parental decision-making on vaccines.","authors":"Dalmacito A Cordero","doi":"10.1177/25151355241277780","DOIUrl":"https://doi.org/10.1177/25151355241277780","url":null,"abstract":"","PeriodicalId":33285,"journal":{"name":"Therapeutic Advances in Vaccines and Immunotherapy","volume":"12 ","pages":"25151355241277780"},"PeriodicalIF":0.0,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11402060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142297008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Monoclonal IgY antibodies: advancements and limitations for immunodiagnosis and immunotherapy applications. 单克隆 IgY 抗体:免疫诊断和免疫疗法应用的进步与局限。
Therapeutic Advances in Vaccines and Immunotherapy Pub Date : 2024-07-25 eCollection Date: 2024-01-01 DOI: 10.1177/25151355241264520
Ashraf A Tabll, Yasser E Shahein, Mohamed M Omran, Nahla A Hussein, Asmaa El-Shershaby, Ana Petrovic, Marija Glasnovic, Robert Smolic, Martina Smolic
{"title":"Monoclonal IgY antibodies: advancements and limitations for immunodiagnosis and immunotherapy applications.","authors":"Ashraf A Tabll, Yasser E Shahein, Mohamed M Omran, Nahla A Hussein, Asmaa El-Shershaby, Ana Petrovic, Marija Glasnovic, Robert Smolic, Martina Smolic","doi":"10.1177/25151355241264520","DOIUrl":"10.1177/25151355241264520","url":null,"abstract":"<p><p>Due to their high specificity and scalability, Monoclonal IgY antibodies have emerged as a valuable alternative to traditional polyclonal IgY antibodies. This abstract provides an overview of the production and purification methods of monoclonal IgY antibodies, highlights their advantages over polyclonal IgY antibodies, and discusses their recent applications. Monoclonal recombinant IgY antibodies, in contrast to polyclonal IgY antibodies, offer several benefits. such as derived from a single B-cell clone, monoclonal antibodies exhibit superior specificity, ensuring consistent and reliable results. Furthermore, it explores the suitability of monoclonal IgY antibodies for low- and middle-income countries, considering their cost-effectiveness and accessibility. We also discussed future directions and challenges in using polyclonal IgY and monoclonal IgY antibodies. In conclusion, monoclonal IgY antibodies offer substantial advantages over polyclonal IgY antibodies regarding specificity, scalability, and consistent performance. Their recent applications in diagnostics, therapeutics, and research highlight their versatility.</p>","PeriodicalId":33285,"journal":{"name":"Therapeutic Advances in Vaccines and Immunotherapy","volume":"12 ","pages":"25151355241264520"},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11273732/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141789327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Developing and validating a scale to measure the perceptions of safety, usability and acceptability of microarray patches for vaccination: a study protocol. 开发并验证用于测量疫苗接种微阵列贴片的安全性、可用性和可接受性的量表:研究方案。
Therapeutic Advances in Vaccines and Immunotherapy Pub Date : 2024-06-24 eCollection Date: 2024-01-01 DOI: 10.1177/25151355241263560
Matthew N Berger, Cristyn Davies, Erin Mathieu, Ramon Z Shaban, Shopna Bag, S Rachel Skinner
{"title":"Developing and validating a scale to measure the perceptions of safety, usability and acceptability of microarray patches for vaccination: a study protocol.","authors":"Matthew N Berger, Cristyn Davies, Erin Mathieu, Ramon Z Shaban, Shopna Bag, S Rachel Skinner","doi":"10.1177/25151355241263560","DOIUrl":"10.1177/25151355241263560","url":null,"abstract":"<p><strong>Background: </strong>Vaccination is a fundamental tenet of public and population health. Several barriers to vaccine uptake exist, exacerbated post-COVID-19, including misconceptions about vaccine efficacy and safety, vaccine hesitancy, vaccine inequity, costs, religious beliefs, and insufficient education and guidance for healthcare professionals. Vaccine uptake may be aided using microarray patches (MAPs) due to reduced pain, no hypodermic needle, enhanced thermostability, and potential for self and lay administration.</p><p><strong>Objectives: </strong>This protocol outlines the development of a scale that aims to accurately measure the perceived safety, usability, and acceptability of MAPs for vaccination among laypeople, MAP recipients, clinicians, and parents or guardians of children.</p><p><strong>Methods and analysis: </strong>This study will follow three phases of scale development and validation, including (1) item development, (2) scale development, and (3) scale evaluation. Inductive (interviews) and deductive methods (literature searches) will be used to develop scale items, which experts from target populations will assess through an online survey. Cognitive interviews will be conducted to observe their processes of answering the draft survey. Thematic analysis will be conducted to analyse qualitative data. Lastly, four surveys will be administered online to our target populations over two time points to determine their repeatability. Exploratory and confirmatory factor analyses, Cronbach's alpha, and construct validity will be performed.</p><p><strong>Ethics: </strong>This study was approved by Metro South Health (HREC/2021/QMS/81653) and Western Sydney Local Health District (2023/ETH00705) Human Research Ethics Committees.</p><p><strong>Discussion: </strong>The scale will support a standardised approach to assessing the social and behavioural aspects of MAP vaccines, enabling comparison of outcomes across studies. Once validated, this scale will assist vaccination programmes in developing effective strategies for integrating MAPs and overcoming barriers to vaccination. This includes improving vaccine equity and accessibility, especially in lower- and middle-income countries and rural or remote locations.</p>","PeriodicalId":33285,"journal":{"name":"Therapeutic Advances in Vaccines and Immunotherapy","volume":"12 ","pages":"25151355241263560"},"PeriodicalIF":0.0,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11265248/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141752996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Routine immunization for children in the Philippines: challenges and interventions. 菲律宾儿童常规免疫接种:挑战与干预措施。
Therapeutic Advances in Vaccines and Immunotherapy Pub Date : 2024-06-24 eCollection Date: 2024-01-01 DOI: 10.1177/25151355241264528
Dalmacito A Cordero
{"title":"Routine immunization for children in the Philippines: challenges and interventions.","authors":"Dalmacito A Cordero","doi":"10.1177/25151355241264528","DOIUrl":"https://doi.org/10.1177/25151355241264528","url":null,"abstract":"","PeriodicalId":33285,"journal":{"name":"Therapeutic Advances in Vaccines and Immunotherapy","volume":"12 ","pages":"25151355241264528"},"PeriodicalIF":0.0,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11265232/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141752997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring social media influences on vaccine decision-making in parents: a netnography. 探究社交媒体对家长疫苗决策的影响:一项网络研究。
Therapeutic Advances in Vaccines and Immunotherapy Pub Date : 2024-05-08 eCollection Date: 2024-01-01 DOI: 10.1177/25151355241249607
Susan E Smith, Nina Sivertsen, Lauren Lines, Anita De Bellis
{"title":"Exploring social media influences on vaccine decision-making in parents: a netnography.","authors":"Susan E Smith, Nina Sivertsen, Lauren Lines, Anita De Bellis","doi":"10.1177/25151355241249607","DOIUrl":"10.1177/25151355241249607","url":null,"abstract":"<p><strong>Background: </strong>Immunization is one of the most significant health initiatives of recent times. Despite this, vaccine hesitancy is increasing and was listed as one of the top 10 threats to global health by the World Health Organization in 2019. A major factor associated with vaccine hesitancy is thought to be the viral spread of misinformation by a small but active anti-vaccination movement.</p><p><strong>Objectives: </strong>The purpose of this study was to explore the influences of social media on vaccine decision-making in parents.</p><p><strong>Design: </strong>This study is part of a larger body of research that explored vaccine decision-making in parents. Other methods included were an online survey and semi-structured interviews. This study investigated the influence of cyberculture on parents in an online environment.</p><p><strong>Method: </strong>This study employed netnography, a form of qualitative inquiry with its roots in ethnography as methodology and a purpose-designed Facebook page as the means of exploring a purpose-designed online community with a particular focus on the culture, belief systems and influences present. Both manual and computer-assisted thematic analyses were used to analyse the data obtained.</p><p><strong>Results: </strong>Three key themes were identified in this study. These included vaccine safety concerns, the emotional debate and COVID-19-specific issues. The results indicated the presence of strong anti-vaccination sentiment combined with an 'infodemic' of conspiracy theories, misinformation and vitriol with the potential to negatively impact parents seeking immunization information.</p><p><strong>Conclusion: </strong>Given the popularity and accessibility of social media and the ready access to misinformation present online, it is evident that parental vaccine decision-making may be impacted adversely. Therefore, it is important that healthcare professionals are aware of this and provide adequate and timely education prior to parents seeking information on social media.</p>","PeriodicalId":33285,"journal":{"name":"Therapeutic Advances in Vaccines and Immunotherapy","volume":"12 ","pages":"25151355241249607"},"PeriodicalIF":0.0,"publicationDate":"2024-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11080448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140899801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adjuvants in COVID-19 vaccines: innocent bystanders or culpable abettors for stirring up COVID-heart syndrome. COVID-19 疫苗中的佐剂:挑起 COVID 心脏综合症的无辜旁观者还是罪魁祸首?
Therapeutic Advances in Vaccines and Immunotherapy Pub Date : 2024-02-04 eCollection Date: 2024-01-01 DOI: 10.1177/25151355241228439
Sri Harsha Kanuri, Prapthi Jayesh Sirrkay
{"title":"Adjuvants in COVID-19 vaccines: innocent bystanders or culpable abettors for stirring up COVID-heart syndrome.","authors":"Sri Harsha Kanuri, Prapthi Jayesh Sirrkay","doi":"10.1177/25151355241228439","DOIUrl":"10.1177/25151355241228439","url":null,"abstract":"<p><p>COVID-19 infection is a multi-system clinical disorder that was associated with increased morbidity and mortality. Even though antiviral therapies such as Remdesvir offered modest efficacy in reducing the mortality and morbidity, they were not efficacious in reducing the risk of future infections. So, FDA approved COVID-19 vaccines which are widely administered in the general population worldwide. These COVID-19 vaccines offered a safety net against future infections and re-infections. Most of these vaccines contain inactivated virus or spike protein mRNA that are primarily responsible for inducing innate and adaptive immunity. These vaccines were also formulated to contain supplementary adjuvants that are beneficial in boosting the immune response. During the pandemic, clinicians all over the world witnessed an uprise in the incidence and prevalence of cardiovascular diseases (COVID-Heart Syndrome) in patients with and without cardiovascular risk factors. Clinical researchers were not certain about the underlying reason for the upsurge of cardiovascular disorders with some blaming them on COVID-19 infections while others blaming them on COVID-19 vaccines. Based on the literature review, we hypothesize that adjuvants included in the COVID-19 vaccines are the real culprits for causation of cardiovascular disorders. Operation of various pathological signaling events under the influence of these adjuvants including autoimmunity, bystander effect, direct toxicity, anti-phospholipid syndrome (APS), anaphylaxis, hypersensitivity, genetic susceptibility, epitope spreading, and anti-idiotypic antibodies were partially responsible for stirring up the onset of cardiovascular disorders. With these mechanisms in place, a minor contribution from COVID-19 virus itself cannot be ruled out. With that being said, we strongly advocate for careful selection of vaccine adjuvants included in COVID-19 vaccines so that future adverse cardiac disorders can be averted.</p>","PeriodicalId":33285,"journal":{"name":"Therapeutic Advances in Vaccines and Immunotherapy","volume":"12 ","pages":"25151355241228439"},"PeriodicalIF":0.0,"publicationDate":"2024-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10846003/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139698505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lessons learned from a cluster of immunization errors in newborns. 从一组新生儿免疫接种错误中汲取教训。
Therapeutic Advances in Vaccines and Immunotherapy Pub Date : 2024-01-02 eCollection Date: 2024-01-01 DOI: 10.1177/25151355231221009
Loubna Alj, Amina Tebaa, Ismail Talibi, Sofia Moubarik, Mohammed Benazzouz, Rachida Soulaymani Bencheikh
{"title":"Lessons learned from a cluster of immunization errors in newborns.","authors":"Loubna Alj, Amina Tebaa, Ismail Talibi, Sofia Moubarik, Mohammed Benazzouz, Rachida Soulaymani Bencheikh","doi":"10.1177/25151355231221009","DOIUrl":"10.1177/25151355231221009","url":null,"abstract":"<p><strong>Background: </strong>Vaccines are safe and effective, but adverse reactions can occur. Immunization errors (IEs) are one of the types of adverse events following immunization. The Moroccan Pharmacovigilance Centre (MPC) received a cluster of IEs from a maternity university hospital (MUH) regarding six newborns who were inadvertently administered rocuronium instead of hepatitis B (HepB) vaccine. The newborns experienced respiratory distress and one had a fatal outcome.</p><p><strong>Objectives: </strong>The study aimed to describe the investigation findings, the underlying causes, and contributing factors of the IEs cluster, and proposed risk minimization actions.</p><p><strong>Design: </strong>We carried out a descriptive analysis of the cluster of IEs related to the HepB vaccine reported to the MPC.</p><p><strong>Methods: </strong>An investigation was conducted by the Ministry of Health according to the World Health Organization guidance. The root cause analysis was performed to identify underlying causes and contributing factors that lead to IE occurrence.</p><p><strong>Results: </strong>The cluster analysis showed that the main contributing factors were the look-alike rocuronium and HepB vaccine packaging, the first-time running HepB vaccination for newborns in the MUH, the lack of a full-time pharmacist, and the unsafe storage of rocuronium and vaccines. The administration of Sugammadex to the newborns followed by their transfer to the neonatal care unit resulted in the recovery of five of the six newborns. Proposed recommendations included (1) raising awareness of healthcare professionals to the risk related to look-alike medications, (2) training nurses to ensure vaccination to implement procedures related to immunization practices, (3) nomination of a full-time pharmacist, (4) reassessment of the safety of drug storage and dispensing at the hospital pharmacy, particularly for high-alert medications.</p><p><strong>Conclusion: </strong>Reporting IEs, particularly serious ones, allows us to identify causes and contributing factors that led to their occurrence. Lessons learned from errors are key to take risk minimization actions to improve vaccine safety worldwide.</p>","PeriodicalId":33285,"journal":{"name":"Therapeutic Advances in Vaccines and Immunotherapy","volume":"12 ","pages":"25151355231221009"},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10762870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139098829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Addressing disparities in funding for robust cancer research. 解决癌症研究资金不足的问题。
Therapeutic Advances in Vaccines and Immunotherapy Pub Date : 2023-12-15 eCollection Date: 2023-01-01 DOI: 10.1177/25151355231219083
Dalmacito A Cordero
{"title":"Addressing disparities in funding for robust cancer research.","authors":"Dalmacito A Cordero","doi":"10.1177/25151355231219083","DOIUrl":"https://doi.org/10.1177/25151355231219083","url":null,"abstract":"","PeriodicalId":33285,"journal":{"name":"Therapeutic Advances in Vaccines and Immunotherapy","volume":"11 ","pages":"25151355231219083"},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10725116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138810615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信