Caspian Journal of Neurological Sciences最新文献_第7页

Covid-19 among Multiple Sclerosis Patients and its Outcomes 多发性硬化症患者的Covid-19及其预后

Caspian Journal of Neurological Sciences Pub Date : 2022-03-06 DOI: 10.32598/cjns.8.2.325.1

Masood Najafi, S. Eskandarieh, N. Rezaeimanesh, Hora Heydari, M. Moosavi, M. Harirchian

{"title":"Covid-19 among Multiple Sclerosis Patients and its Outcomes","authors":"Masood Najafi, S. Eskandarieh, N. Rezaeimanesh, Hora Heydari, M. Moosavi, M. Harirchian","doi":"10.32598/cjns.8.2.325.1","DOIUrl":"https://doi.org/10.32598/cjns.8.2.325.1","url":null,"abstract":"Background: COVID-19 is a highly contagious disease and has resulted in 4533645 deaths until September first, 2021. Since Multiple sclerosis (MS) patients receive Immunosuppressive drugs there is a concern that these drugs will reduce the patient's immune system resistance against COVID19. Objectives: This study was performed to evaluate the epidemiology of COVID19 and it's impact on MS patients in our university hospital in Tehran, Iran. Materials & Methods: A cross-sectional study was conducted based on hospital-based registry data from May 2020 to March 2021. Among more than 500 registered MS patients in Imam Khomeini Hospital in Tehran who referred within the period of time of our study, 84 patients were reported of infection by SARS-COV2. The diagnosis of MS was confirmed by the McDonald criteria and the diagnosis of COVID-19 in MS patients was made by real time-PCR technique and chest computed tomography. Results: Out of 84 MS patients who were infected by SARS-COV2, 55(65.5%) were women and their mean age was 37.48 years. The most commonly used drugs by MS patients were Rituximab 20 (26.3%) and Dimethyl Fumarate 14(18.4%).Totally 9(10.8%) of the patients needed to be hospitalized due to COVID-19 with mean hospitalization duration of 5.88 days. A total of 1 (1.2%) death was reported. Discussion: In comparison to normal population, it seems that COVID-19 is not more serious in MS patients. Most of the MS patients with COVID-19 infection were not hospitalized and continued their medication during the course of the infection.","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"83 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76292724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact Of COVID-19 Pandemic On Neuromyelitis Optica Disorder Patients, After one Year COVID-19大流行对视神经脊髓炎患者一年后的影响

Caspian Journal of Neurological Sciences Pub Date : 2022-03-06 DOI: 10.32598/cjns.8.2.328.1

F. Ashtari, R. Mehdipour

{"title":"The Impact Of COVID-19 Pandemic On Neuromyelitis Optica Disorder Patients, After one Year","authors":"F. Ashtari, R. Mehdipour","doi":"10.32598/cjns.8.2.328.1","DOIUrl":"https://doi.org/10.32598/cjns.8.2.328.1","url":null,"abstract":"Background: Coronavirus 2019 created a pandemic with high mortality recently. People with underlying disease are prone to severe infection. The nature of NMOSD disease and its treatment by immunosuppressant predisposes patients to infection. Objectives: The aim of this study was to evaluate the effect of COVID-19 pandemic on the clinical course of NMOSD and also the characteristics of COVID-19 infection in NMOSD patient. Materials & Methods: This descriptive study was done in Isfahan, Iran from March 2020 to March 2021. We considered relapses during the year of epidemic and the year before, and also the presentation of COVID-19 infection in the patients of NMOSD Clinic of Isfahan Kashani hospital. Results: Study included 120 patients. Their mean age was 36.37±9.69 and mean duration of disease was 8.49±5.35 years. They experienced overall 36 relapses during the year before epidemic (ARR:0.3) and 29 relapses during COVID-19 epidemic (ARR is 0.24). The maintenance therapy of NMOSD was rituximab in 96 cases, azathioprine in 22 and methotrexate in 2 ones. 35 patients infected by COVID-19 (based on RT-PCR test). 6 of them admitted in hospital and two patients received ICU care. There was one death due to respiratory failure. Conclusion: In spite of suppression of the immune system, neither incidence nor the number of the serious complications of COVID-19 infection was high. Therefore, regarding the disabling nature of NMOSD as well as prolonged epidemic period, it may be reasonable to continue the routine treatment of these patients along with training patients to stick to health protection instructions.","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87652751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Time-Trend of Multiple Sclerosis Incidence and Prevalence in Khuzestan Province, Iran 伊朗胡齐斯坦省多发性硬化症发病率和患病率的时间趋势

Caspian Journal of Neurological Sciences Pub Date : 2022-03-06 DOI: 10.32598/cjns.8.2.298.1

M. Dastoorpoor, Narges Khodadadi, Nastaran Majdinasab, M. Soltani, S. Ghanbari

{"title":"The Time-Trend of Multiple Sclerosis Incidence and Prevalence in Khuzestan Province, Iran","authors":"M. Dastoorpoor, Narges Khodadadi, Nastaran Majdinasab, M. Soltani, S. Ghanbari","doi":"10.32598/cjns.8.2.298.1","DOIUrl":"https://doi.org/10.32598/cjns.8.2.298.1","url":null,"abstract":"Background: The prevalence and incidence of Multiple Sclerosis (MS) have increased in Iran. Objectives: This study aimed to observe the temporal trends and provide a predictive model in the prevalence and incidence of MS in Khuzestan Province, Iran. Methods: This cross-sectional study was performed from 2006 to 2019 in Khuzestan Province, Southwestern Iran, on 2676 patients registered in the Khuzestan Multiple Sclerosis Center. The simple exponential smoothing model was used to study the time trends and predict the prevalence and incidence of MS in 2020. Results: The mean(SD) age of the examined patients with MS was 31.40(8.94) years; while the mean(SD) age-incidence of MS was 29.19(9.16) years. The sex ratio (female to male) was measured as 3.05. The patients' prevalence and average annual incidences were 57.77 and 4.35per 100000 individuals from 2006 to 2019, respectively. The trend in the MS incidence has been upward with a very slight slope during the years 2006 to 2019. The slope of the increase from 2006 to 2019 was higher for women than men. Conclusions: The collected results suggested that Khuzestan Province is a high-risk area for MS; the prevalence and incidence of the disease are increasing, especially in women. We prognosticate a slight increase in the incidence of MS in the age group of 20 to 50 years. However, the prevalence of the disease in this age group was similar to 2019.","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"61 5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89802187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Translation and Validation of the Persian Version of Mindful Eating Questionnaire 波斯语正念饮食问卷的翻译与验证

Caspian Journal of Neurological Sciences Pub Date : 2022-03-06 DOI: 10.32598/cjns.8.2.24.7

Sajjad Rezaei, Elham Jahanbin

{"title":"Translation and Validation of the Persian Version of Mindful Eating Questionnaire","authors":"Sajjad Rezaei, Elham Jahanbin","doi":"10.32598/cjns.8.2.24.7","DOIUrl":"https://doi.org/10.32598/cjns.8.2.24.7","url":null,"abstract":"Background: Wrong eating behaviors increase the risk of numerous chronic diseases. This study aims to determine the validity and reliability of the Mindful Eating Questionnaire (MEQ) in the Iranian population. Methods: In a validation study at the University of Guilan City, Iran, in 2019-2020. First, the MEQ was translated based on the forward-backward method. After applying the changes to the Persian version of MEQ (P-MEQ), 50 participants responded to the P-MEQ twice with an interval of 3 weeks. Then, 384 Iranian students selected by the two-stage cluster sampling method completed the P-MEQ to determine its construct validity. Sixty participants simultaneously filled the P-MEQ and the Freiburg Mindfulness Inventory (FMI-SF) to determine concurrent validity. To determine known-group validity, 23 very obese participants and a Body Mass Index (BMI) [W1] of over 35 kg/m2 were compared to individuals with a healthy weight (BMI: 18.5-24.9 kg/m2. Results: The test-retest reliability of the P-MEQ was obtained as 0.59 for the total score, and it ranged from 0.58 to 0.79 for the subscales. The first-order confirmatory factor analysis (CFA) results indicated that after removing four items with weak factor loading, the five-factor P-MEQ model had appropriate goodness of fit (χ2/df=2.516, RMSEA=0.067, AGFI=0.835, IFI=0.924, & CFI=0.916). The second-order CFA revealed that the latent components of awareness, distraction, disinhibition, emotional response, and external cues reflected the concept of higher levels of mindful eating acceptably (χ2/df=2.545, RMSEA=0.067, AGFI=0.825, IFI=0.912, ‌& CFI=0.905). However, there was a poor relationship between the total score of P-MEQ and FMI-SF (r=0.24, P=0.07). Conclusion: Regardless of concurrent validity, the Persian version of MEQ has proper construct validity, test-retest reliability, and internal consistency.","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82544527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of Bridging Integrator 1 Gene Polymorphism with Susceptibility to Alzheimer’s Disease 桥接整合子1基因多态性与阿尔茨海默病易感性的关系

Caspian Journal of Neurological Sciences Pub Date : 2022-03-06 DOI: 10.32598/cjns.8.2.213.3

A. Saberi, Zohair Niroomand, A. Ghayeghran, F. Ajamian, Ashkan Karimi, Samaneh Ghorbani Shirkouhi, S. Andalib

{"title":"Association of Bridging Integrator 1 Gene Polymorphism with Susceptibility to Alzheimer’s Disease","authors":"A. Saberi, Zohair Niroomand, A. Ghayeghran, F. Ajamian, Ashkan Karimi, Samaneh Ghorbani Shirkouhi, S. Andalib","doi":"10.32598/cjns.8.2.213.3","DOIUrl":"https://doi.org/10.32598/cjns.8.2.213.3","url":null,"abstract":"Background: Alzheimer's disease (AD) is the most common type of dementia. The role of genetic factors in the development of AD has not been demonstrated yet. Objectives In this study, our aim was to investigate the association between one of the BIN1 gene’s single-nucleotide polymorphism (SNP( (rs744373) and late-onset Alzheimer's disease (LOAD) in an Iranian population in the Guilan province. Materials & Methods: In this case-control study, 110 patients with LOAD, and 110 unrelated healthy controls were recruited. Polymerase chain reaction-restriction length polymorphism (PCR-RFLP) was performed for genotyping BIN1 gene’s SNP (rs744373). Electrophoresis was there after carried out using agarose gel and DNA safe stain and the gels were visualized under an ultraviolet (UV) trans-illuminator. The allelic and genotypic frequencies were determined. Results: The frequency of allele T (Wild-type allele) in the control and the LOAD groups was 70.9% (n = 159) and 58.6% (n = 129), respectively (p = 0.007). The frequency of allele C in the LOAD group (41.4%) (n = 91) was significantly higher than that of the control group (29.1%) (n=64) (p=0.007). Frequency of homozygous genotype (CC) of BIN was significantly higher in the LOAD group than in the control group (p = 0.043). Conclusion: rs744373 SNP of BIN1 gene is significantly associated with the risk of developing AD in the studied population.","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88647884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychological Distress in Patients with Multiple Sclerosis and Epilepsy During the COVID-19 Pandemic: Systematic Review Study COVID-19大流行期间多发性硬化症和癫痫患者的心理困扰:系统评价研究

Caspian Journal of Neurological Sciences Pub Date : 2022-03-06 DOI: 10.32598/cjns.8.2.283.2

F. Bagheri Sheykhangafshe, Mina Fathi-Ashtiani, A. Fathi-Ashtiani

{"title":"Psychological Distress in Patients with Multiple Sclerosis and Epilepsy During the COVID-19 Pandemic: Systematic Review Study","authors":"F. Bagheri Sheykhangafshe, Mina Fathi-Ashtiani, A. Fathi-Ashtiani","doi":"10.32598/cjns.8.2.283.2","DOIUrl":"https://doi.org/10.32598/cjns.8.2.283.2","url":null,"abstract":"Background: COVID-19 as a pandemic can cause a set of feelings of anxiety, fear and tension in society. In fact, the negative impact of pandemic is not limited to physical health problems and can have serious consequences such as anxiety, depression and stress in people, especially those with neurological diseases. Objectives: The present study was conducted to investigate depression, anxiety and stress in patients with multiple sclerosis and epilepsy during the COVID-19 pandemic. Materials & Methods: In this study, the keywords Depression, Anxiety, Stress, Multiple Sclerosis, Epilepsy and COVID-19 in the title and abstract of articles published in 2020 (May) and 2021 (July) in reputable international scientific databases Searched for Google Scholar, PubMed, Scopus, EMBASE and PsycINFO. The PRISMA checklist was used to review and control the quality of articles. Results: In the search, 394 English articles were retrieved and finally 27 final articles were selected for comprehensive review and data extraction. The results showed that patients with multiple sclerosis and epilepsy experienced depression, anxiety, stress, fear, poor sleep quality, mental fatigue and poor quality of life during the COVID-19 pandemic. Quarantine has limited patients' access to medication and treatment, resulting in increased seizures and disease severity. Conclusion: The COVID-19 pandemic reduced the mental health of patients with multiple sclerosis and epilepsy. Given that the psychological consequences of the outbreak of COVID-19 are possible to be associated with patients with multiple sclerosis and epilepsy for years, it is necessary to adopt psychological interventions to reduce psychological distress in these patients","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78321680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Morphine Consumption During Lactation Impairs Short-Term Neuronal Plasticity in Rat Offspring CA1 Neurons 哺乳期吗啡摄入损害大鼠后代CA1神经元的短期可塑性

Caspian Journal of Neurological Sciences Pub Date : 2022-03-06 DOI: 10.32598/cjns.8.2.321.1

Fatemeh Aghighi, M. Shabani, S. Talaei

{"title":"Morphine Consumption During Lactation Impairs Short-Term Neuronal Plasticity in Rat Offspring CA1 Neurons","authors":"Fatemeh Aghighi, M. Shabani, S. Talaei","doi":"10.32598/cjns.8.2.321.1","DOIUrl":"https://doi.org/10.32598/cjns.8.2.321.1","url":null,"abstract":"Background: Facing environmental factors during early postnatal life, directly or indirectly via mother-infant relationships, profoundly affects the structure and function of the mammals’ Central Nervous System (CNS). Objectives: This study aimed to evaluate the effect of morphine consumption during the lactation period on short-term synaptic plasticity of the hippocampal Cornu Ammonis 1 (CA1) neurons in rat offspring. Methods: In addition to a group of control mother rats (CO), three groups subcutaneously received 5 (M5), 10 (M10), or 20 (M20) mg/kg morphine every 12 hours during the lactation period. At 45 days old, following the stimulation of the Schaffers’ collaterals, basic field Excitatory Post-Synaptic Potentials (fEPSPs) were recorded in their offspring's hippocampal CA1 neuronal circuits. After the construction input/output curve, paired-pulse stimulations with the inter-stimulus intervals of 20, 80, and 200 ms were applied to determine the short-term synaptic plasticity, and the paired-pulse ratio was evaluated. Results: The baseline synaptic responses of the rats CA1 neurons whose mothers received 10 and 20 mg/kg morphine twice daily during the lactation period decreased compared to the CO animals (P<0.01 & P<0.001, respectively). Furthermore, compared to the controls, the Paired-Pulse Ratio (PPR) of the CA1 neural circuits of M10 and M20 rats at 20 and 80 ms Inter-Stimulus Intervals (ISI) decreased (P<0.01). Conclusions: Morphine exposure during the lactation period has a detrimental impact on the primary synaptic activity and short-term synaptic plasticity of the hippocampal CA1 neuronal circuits of rats’ offspring.","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90520824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Effects of Photobiomodulation on Shoulder Pain, Muscle Thickness, and Function in Subjects With Adhesive Capsulitis 光生物调节对粘连性囊炎患者肩痛、肌肉厚度和功能的影响

Caspian Journal of Neurological Sciences Pub Date : 2022-03-06 DOI: 10.32598/cjns.8.2.100.3

K. Ezzati, Amir-Masoud Salari, Saemeh Khani, A. Aris

{"title":"The Effects of Photobiomodulation on Shoulder Pain, Muscle Thickness, and Function in Subjects With Adhesive Capsulitis","authors":"K. Ezzati, Amir-Masoud Salari, Saemeh Khani, A. Aris","doi":"10.32598/cjns.8.2.100.3","DOIUrl":"https://doi.org/10.32598/cjns.8.2.100.3","url":null,"abstract":"Background: Adhesive capsulitis or frozen shoulder is among the most prevalent causes of pain and disability in individuals. We aimed to evaluate the effect of Photobiomodulation (PBM) on pain, range of motion, and thickness and function of supraspinatus muscle in patients with adhesive capsulitis. Materials & Methods: Overall, 52 subjects (n=26/group) with adhesive capsulitis referring to Poorsina Hospital, physiotherapy ward, Rasht City, Iran, in 2019 participated in this study. They were randomly assigned to 2 groups of control or routine physical therapy and PBM group. The variables were pain (VAS), range of motion (goniometer), the supraspinatus muscle thickness in rest and contraction, and muscle function (ultrasonography). The outcomes were examined before, after 5 and 10 sessions, and at a 1-month follow-up. Results: There were no significant differences between the two groups regarding the demographic characteristics and studied variables. The interaction of group and time (2×4) was significant for pain (P=0.02). Finally, the Bonferroni post hoc test data indicated the pain reduction in the PBM group was higher than the control group at the follow-up (P=0.03). The mixed two-factor analysis of variance indicated that the interaction of the group and time of shoulder abduction (P=0.6), shoulder external rotation (0.46), supraspinatus muscle thickness, rest (0.31), supraspinatus muscle thickness, contraction (0.11), and rest-contraction (0.66) were not significant. Conclusions: The PBM revealed greater analgesic effects than routine physical therapy in the short term and one-month follow-up. However, the effects on a range of motion and muscle thickness and function were insignificant.","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73942803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Guillain-Barré Syndrome During the COVID-19 Pandemic and Pre-pandemic Periods COVID-19大流行期间和大流行前期间的格林-巴勒综合征

Caspian Journal of Neurological Sciences Pub Date : 2022-01-01 DOI: 10.32598/cjns.8.28.213.2

Alyeh Besharati, A. Saberi, Samaneh Ghorbani Shirkouhi, A. Ashraf, H. Hatamian, Habib Eslami Kenarsari, S. Andalib

{"title":"Guillain-Barré Syndrome During the COVID-19 Pandemic and Pre-pandemic Periods","authors":"Alyeh Besharati, A. Saberi, Samaneh Ghorbani Shirkouhi, A. Ashraf, H. Hatamian, Habib Eslami Kenarsari, S. Andalib","doi":"10.32598/cjns.8.28.213.2","DOIUrl":"https://doi.org/10.32598/cjns.8.28.213.2","url":null,"abstract":"Background: Guillain-Barré Syndrome (GBS) is an autoimmune disease that may occur after infections. As Coronavirus Disease 2019 (COVID-19) may bring about GBS, it is important to assess the effect of the COVID-19 pandemic on this disease Objectives: This study aimed to compare the distribution and characteristics of GBS during and before the COVID-19 pandemic in an academic referral hospital in the north of Iran. Materials & Methods: This retrospective study assessed GBS distribution and characteristics during the COVID-19 pandemic period (from March 2020 to the end of February 2021) and before the pandemic (from March 2019 to the end of February 2020) on 5340 patients referred to the Neurology Ward of Poursina Hospital of Guilan Province, in Iran. Results: There was no significant difference between GBS distribution during (0.03%) and before (0.04%) the COVID-19 pandemic (P=0.413). There were also no differences between the two periods regarding the gender (P=0.659) and age (P=0.417) of the patients. The most common subtype of GBS during the COVID-19 pandemic was Acute Motor and Sensory Axonal Neuropathy (AMSAN) (71.4%). In both periods, the most common type of treatment was intravenous administration of immune globulin. There was no significant difference between the two periods (P=0.838) regarding the patients’ treatment response. Conclusion: The distribution of GBS, its subtypes, type of treatment, and response to treatment were not different between the two study periods.","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79877085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Suicidal Ideations in Patients With Obsessive-Compulsive Disorder 强迫症患者的自杀意念

Caspian Journal of Neurological Sciences Pub Date : 2022-01-01 DOI: 10.32598/cjns.8.28.287.1

M. Khalkhali, R. Zare, H. Farrahi, Peyvand Shambayati

{"title":"Suicidal Ideations in Patients With Obsessive-Compulsive Disorder","authors":"M. Khalkhali, R. Zare, H. Farrahi, Peyvand Shambayati","doi":"10.32598/cjns.8.28.287.1","DOIUrl":"https://doi.org/10.32598/cjns.8.28.287.1","url":null,"abstract":"Background: There are many controversies about the frequency and burden of suicidality in patients with Obsessive-Compulsive Disorder (OCD). Objectives: This study was done to determine the prevalence and risk factors of current suicidal ideations in patients with OCD. Materials & Methods: In this cross-sectional study, 258 outpatients with OCD (Yale-Brawn Obsessive Compulsive Scale, Y-BOCS ≥16) referring to two psychiatry clinics in Guilan, Iran, from March 2018 to September 2019 were evaluated. Suicidality score of the Brief Psychiatric Rating Scale (BPRS) ≥4 was considered for current suicidal ideation at the first visit. Beck Scale for Suicidal Ideation (BSSI) was used to evaluate the intensity of suicidal ideations a week before evaluation. Simple linear and binary logistic regression analyses were used to analyze data by SPSS v. 20. Results: Current suicidal ideation was found in 22.1% of patients. The previous history of suicide attempt (BPRS, P<0.0001 and BSSI, P<0.0001), a history of OCD in first-degree relatives (BPRS: P=0.004 and BSSI: P=0.010), a history of suicide attempts in first-degree relatives (BPRS: P=0.013 and BSSI: P<0.0001), comorbid diagnosis of depressive or body dysmorphic disorder (BPRS, P<0.0001 and BSSI, P<0.0001), and higher Y-BOCS score (BPRS: P=0.043 and BSSI: P<0.0001) were associated with a higher risk of having suicidal ideation. Conclusion: Suicidal thoughts are high in Iranian patients with OCD at their first visit to psychiatry clinics. The previous suicide history, positive history of OCD and suicide attempts in their first-degree relatives, the severity of OCD, and some comorbid psychological disorders are associated with a higher risk of suicidal ideation among OCD patients.","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90480885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0