{"title":"Effects of Metformin, Avocado Seed, and Diabetic Ingredients Infusion to Weight and Fasting Blood Glucose on Sucrose Diet Rats","authors":"D. Jasaputra, T. Wargasetia, Elizabeth Elizabeth","doi":"10.29313/GMHC.V7I1.2917","DOIUrl":"https://doi.org/10.29313/GMHC.V7I1.2917","url":null,"abstract":"Metformin, an oral hypoglycemic drug which has metabolic effects and weight loss after 6–9 months; however, after 18 months, these effects disappear. Oral hypoglycemic drugs with no effect on raising the weight are needed. The objective of the study is comparing the effects of metformin, avocado seed infusion (AS), and diabetic ingredients/DI (green chiretta, Java tea, and bitter grapes) in increasing weight and fasting blood glucose of rats with sucrose diet. The research was conduct at the Pharmacology Laboratory, Faculty of Medicine Universitas Kristen Maranatha in February–August 2017. The results showed that metformin within six weeks reduced weight (75.55%) compared to control (+) with a hypercaloric diet (114.36%). Metformin and hypercaloric diet in rats for 14 weeks showed a 125.66% increase in weight, higher than control (+) (114.36%), although not significant (p>0.05). Weight in rats with hypercaloric and AS diet for 14 weeks was 94.30% and 81.68% in DI was lower than control (+) (114.36%), but not significant (p>0.05). Fasting blood glucose (FBG) of dietary hypercaloric rats and metformin was 123.75 mg/dL, higher than control (+), which was 85.75 mg/dL (p 0.05). In conclusions, metformin increased rats body weight even though not significantly and fasting blood glucose in rats fed a hypercaloric diet for 14 weeks, while avocado seed infusion and diabetec ingredients infusion did not. EFEK METFORMIN, INFUSI BIJI ALPUKAT, DAN INFUSI RAMUAN DIABETES TERHADAP BERAT BADAN DAN GLUKOSA DARAH PUASA PADA TIKUS DIET SUKROSA Metformin, obat hipoglikemik oral berefek metabolik dan menurunkan berat badan (BB) setelah 6–9 bulan, namun setelah 18 bulan efek ini hilang. Diperlukan obat hipoglikemik oral yang tidak berefek meningkatkan BB. Tujuan penelitian ini membandingkan efek metformin, infusi biji alpukat (BA), dan infusi ramuan diabetes/RD (sambiloto, kumis kucing, dan bratawali) dalam meningkatkan BB dan glukosa darah puasa pada tikus diet sukrosa. Penelitian dilaksanakan di Laboratorium Farmakologi, Fakultas Kedokteran Universitas Kristen Maranatha periode Februari–Agustus 2017. Hasil penelitian menunjukkan metformin dalam waktu 6 minggu mengurangi penambahan BB (75,55%) dibanding dengan kontrol (+) diet hiperkalori (114,36%). Pemberian metformin dan diet hiperkalori pada tikus selama 14 minggu menunjukkan kenaikan BB 125,66%, lebih tinggi dibanding dengan kontrol (+) (114,36%), walaupun tidak signifikan (p>0,05). Berat badan pada tikus dengan diet hiperkalori dan infusi BA selama 14 minggu adalah 94,30% dan RD 81,68%, lebih rendah dibanding dengan kontrol (+) (114,36%), namun tidak signifikan (p>0,05). Glukosa darah puasa (GDP) tikus diet hiperkalori dan metformin adalah 123,75 mg/dL, lebih tinggi dibanding dengan kontrol (+) 85,75 mg/dL (p 0,05). Simpulan, metformin meningkatkan berat badan tikus walau tidak signifikan dan meningkatkan glukosa darah puasa pada tikus diet hiperkalori selama 14 minggu, sedangkan infusi biji alpukat dan ramuan ","PeriodicalId":312900,"journal":{"name":"Global Medical & Health Communication (GMHC)","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114758525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Ismiyati, U. Sabarudin, Tuti Wahmurti A. Sapiie, Farid Husin, Susi Susanah, D. Sunjaya
{"title":"Reproductive Health Problems in Adolescents in Banten Province","authors":"I. Ismiyati, U. Sabarudin, Tuti Wahmurti A. Sapiie, Farid Husin, Susi Susanah, D. Sunjaya","doi":"10.29313/GMHC.V7I1.3060","DOIUrl":"https://doi.org/10.29313/GMHC.V7I1.3060","url":null,"abstract":"Teenagers are the next generation that needs to be the center of attention. Physical and mental development in adolescents occurs rapidly. The process of changing times with free association arises causing debate about their reproductive health. The purpose of this study was to determine the reproductive health problems of adolescents in Banten province. This study used a qualitative design and constructivism paradigm. The research method was using the in-depth interview guideline instrument with 11 informants conducted in Banten province in January−June 2017. Qualitative data analysis using content analysis. The results showed that environmental factors such as family, relationships, health workers, and the availability of prostitution practice were trigger teenagers' problems. The environment did not support them to learn about sexuality makes them seek information from sources that cannot be justified. This practice made adolescents have inappropriate knowledge about adolescent reproductive health. The availability of prostitution practice was a unique highlight for those who can channel their curiosity in fulfilling their sexual desires. In conclusions, adolescent reproductive health problems in Banten province consisted of premarital sex behavior, teenage pregnancy, teenage marriage, youth delivery, sexually transmitted diseases, and abnormal sexual behavior. These problems arise due to factors of knowledge, environment, and family economic status. PERMASALAHAN KESEHATAN REPRODUKSI PADA REMAJA DI PROVINSI BANTEN Remaja merupakan generasi penerus yang perlu menjadi pusat perhatian. Perkembangan fisik dan mental pada remaja terjadi secara pesat. Proses perubahan zaman dengan pergaulan bebas memicu timbulnya permasalahan kesehatan reproduksi pada mereka. Tujuan penelitian ini mengetahui permasalahan kesehatan reproduksi remaja di Provinsi Banten. Penelitian ini menggunakan desain kualitatif dan paradigma konstruktivisme. Metode penelitian menggunakan instrumen wawancara mendalam kepada 11 informan yang dilakukan di Provinsi Banten pada bulan Januari–Juni 2017. Analisis data kualitatif menggunakan analisis konten. Hasil penelitian menunjukkan bahwa faktor lingkungan seperti keluarga, pergaulan, tenaga kesehatan, dan ketersediaan tempat prostitusi memicu permasalahan remaja. Lingkungan yang tidak mendukung mereka untuk belajar tentang seksualitas membuat mereka mencari informasi dari sumber yang tidak dapat dipertanggungjawabkan kebenarannya. Hal tersebut membuat remaja memiliki pengetahuan yang tidak tepat tentang kesehatan reproduksi remaja. Ketersediaan tempat-tempat prostitusi menjadi sorotan khusus bagi mereka yang dapat menyalurkan keingintahuan mereka dalam memenuhi hasrat seksualitas. Simpulan, permasalahan kesehatan reproduksi remaja di Provinsi Banten terdiri atas perilaku seks pranikah, kehamilan remaja, pernikahan remaja, persalinan remaja, penyakit seksual, dan perilaku seks menyimpang. Permasalahan tersebut muncul karena faktor ling","PeriodicalId":312900,"journal":{"name":"Global Medical & Health Communication (GMHC)","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125249083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Susilawati, Farid Husin, F. Wirakusumah, Meita Dhamayanti, Herry Herman, Ruswana Anwar, N. Sekarwana
{"title":"The Use Reproductive Health Game (KEPO Game) on Female Adolescent’s Five Dimensions Satisfaction","authors":"S. Susilawati, Farid Husin, F. Wirakusumah, Meita Dhamayanti, Herry Herman, Ruswana Anwar, N. Sekarwana","doi":"10.29313/GMHC.V7I1.2966","DOIUrl":"https://doi.org/10.29313/GMHC.V7I1.2966","url":null,"abstract":"The adolescent’s reproductive health is the major problem that should take into consideration. To solve this problem, it needs an alternative strategy by using a media, reproductive health/ kesehatan reproduksi (KEPO) game, in Android smartphone. The aim is analyzing the effect of KEPO game on the five dimensions of female adolescent’s satisfaction. The research method was quasi-experiment, and the research design used pre-test post-test with control group design. The sampling technique used simple random sampling. The subject was 64 respondents of female student age of 12−15 years old in public junior high school in Bandung city. The respondents divided into two groups, the first one treated by KEPO game is 32 students of Public Junior High School 50 Bandung, while the control group was 32 students of Public Junior High School 8 Bandung, get counseling from Ujungberung Indah Public Health Center; the entire research conducted in April−May 2017. Research result shows the percentage differential of satisfaction average score improvement on both groups. The treatment group produces percentage of content 14.6%, display 23.6%, accuracy 11.4%, easiness 12.4%, and correctness 17%. In the other hand, control group produces content 5%, display 3%, accuracy 4.3%, easiness 2.8%, and correctness 4.7% with a p value for each indicator was p 0,05 kelompok kontrol. Secara keseluruhan, diketahui bahwa kepuasan remaja dari kelima aspek kepuasan dalam menggunakan gim KEPO memiliki perbedaan yang bermakna p<0,05 dengan persentase puas 84%. Simpulan, terdapat pengaruh penggunaan gim KEPO terhadap lima dimensi kepuasan remaja perempuan.","PeriodicalId":312900,"journal":{"name":"Global Medical & Health Communication (GMHC)","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122172240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fecal Calprotectin in Preterm Infants Sepsis with and without Necrotizing Enterocolitis Symptoms","authors":"Y. Suryani, D. Prasetyo, D. Hilmanto","doi":"10.29313/GMHC.V6I3.3337","DOIUrl":"https://doi.org/10.29313/GMHC.V6I3.3337","url":null,"abstract":"Necrotizing enterocolitis (NEC) is one of the severe gastrointestinal disorder that predominantly affects preterm infants with high morbidity and mortality. The initial clinical manifestations of NEC are non-specific and indistinguishable from sepsis which making delay in diagnosis. Delayed diagnosis might require surgery and even cause death. Calprotectin is a calcium-binding protein, abundantly present in cytosol fraction of neutrophils, also found in feces, and has been found to increase significantly in gastrointestinal inflammation. This study purpose to compare fecal calprotectin in sepsis preterm infants with symptoms of NEC to sepsis preterm infants without symptoms of NEC. The study was a comparative cross-sectional analytic study performed at the Neonatology ward of Dr. Hasan Sadikin General Hospital Bandung, from October 2013 to January 2014 on 40 sepsis preterm infants aged <28 days. Fecal calprotectin was analyzed using enzyme-linked immunoassay (ELISA) kit. Mann-Whitney U test was used to compare the difference of fecal calprotectin concentration in both groups. There were 20 sepsis preterm infants with symptoms of NEC compared to 20 sepsis infants without abdominal symptoms. The concentration of fecal calprotectin was significantly higher in preterm sepsis infants with symptoms of NEC (790.67 μg/g) than preterm sepsis infants without symptoms of NEC (247.93 μg/g, p=0.019). The increasing of fecal calprotectin might provide relevant clinical information to pediatricians for early warning signs of NEC in preterm sepsis infants. In conclusion, fecal calprotectin in preterm sepsis infants with symptoms of NEC is higher compared to those without abdominal symptoms. CALPROTECTIN FESES PADA BAYI KURANG BULAN SEPSIS DENGAN DAN TANPA GEJALA ENTEROKOLITIS NEKROTIKANSEnterokolitis nekrotikans (EKN) merupakan salah satu gangguan gastrointestinal yang serius terutama pada bayi kurang bulan dengan angka kesakitan dan kematian yang tinggi. Gejala klinis awal EKN yang tidak spesifik dan sulit dibedakan dengan sepsis menyebabkan keterlambatan diagnosis. Keterlambatan diagnosis dapat menyebabkan diperlukan tindakan pembedahan bahkan kematian. Calprotectin merupakan protein yang berikatan dengan kalsium banyak terdapat dalam sitosol neutrofil, dapat ditemukan dalam feses, dan diketahui meningkat signifikan pada keadaan inflamasi gastrointestinal. Penelitian ini bertujuan membandingkan kadar calprotectin feses pada bayi kurang bulan (BKB) sepsis dengan BKB sepsis tanpa gejala EKN. Penelitian ini merupakan penelitian observasional analitik dengan rancangan kasus kontrol yang dilakukan di ruang rawat Neonatologi RSUP Dr. Hasan Sadikin Bandung dari Oktober 2013 sampai Januari 2014 terhadap 40 BKB sepsis berusia <28 hari. Kadar calprotectin feses dianalisis menggunakan kit enzim-linked immunoassay (ELISA). Analisis data menggunakan Mann-Whitney U test untuk membandingkan kadar calprotectin feses antara kedua kelompok. Terdapat 20 BKB sepsis dengan gejala ","PeriodicalId":312900,"journal":{"name":"Global Medical & Health Communication (GMHC)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132112373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Two Serial Hematocrit Level Just After Admission to Predict Dengue Hemorrhagic Fever Severity","authors":"Fauziyyah Ramadhani, M. Ghozali, Leni Lismayanti","doi":"10.29313/GMHC.V6I3.3079","DOIUrl":"https://doi.org/10.29313/GMHC.V6I3.3079","url":null,"abstract":"Dengue hemorrhagic fever (DHF) is still the leading cause of hospitalization and death among children in Indonesia because of plasma leakage leading to shock syndromes. This study aimed to associate the hematocrit difference (first and second) from serial hematocrit (Hct) examination just after admission with DHF severity. A analytical cross-sectional study was involving medical records of pediatric patients with DHF admitted at the pediatric ward and the Pediatric Intensive Care Unit (PICU) of Dr. Hasan Sadikin General Hospital, Bandung in January–December 2015. The subjects excluded if other conditions also cause plasma leakage. The difference in first and second Hct (∆Hct) from serial Hct examination just after admission and DHF grade of severity (DHF I–IV) confirmed by a positive result in serologic tests (anti-dengue IgM/IgG), or detection of dengue virus antigen (NS1Ag test) obtained. Spearman association analysis test used for analysis. A total of 16 subjects with DHF I, 21 subjects with DHF II, 31 subjects with DHF III and two subjects with DHF IV included in this study. There was no significant correlation between positive ∆Hct value (hemoconcentration) and DHF severity (r=0.247, p=0.394, CI=95%). In conclusion, the difference in first and second Hct from serial Hct examination just after admission has no significant association with the disease severity. DUA NILAI HEMATOKRIT SERIAL SESAAT SETELAH ADMISI SEBAGAI PREDIKTOR KEPARAHAN DEMAM BERDARAH DENGUEDemam berdarah dengue (DBD) merupakan penyebab utama hospitalisasi dan kematian anak di Indonesia disebabkan oleh kebocoran plasma yang berujung pada syok. Tujuan penelitian ini mengetahui hubungan perbedaan hematokrit pertama dan kedua pada pemeriksaan hematokrit serial sesaat setelah admisi dengan keparahan DBD. Penelitian merupakan analytical cross-sectional study menggunakan data sekunder berupa rekam medis pasien anak yang dirawat di ruang perawatan anak dan Pediatric Intensive Care Unit (PICU) RSUP Dr. Hasan Sadikin Bandung pada Januari–Desember 2015. Subjek penelitian dieksklusi apabila pada rekam medis terdapat diagnosis lain yang menyebabkan kebocoran plasma. Variabel penelitian ini adalah perbedaan hematokrit pertama dan kedua (∆Hct) pada pemeriksaan hematokrit serial serta diagnosis DBD (DBD I–IV) yang dikonfirmasi oleh hasil positif pada pemeriksaan serologis (IgM/IgG antidengue) atau deteksi antigen virus (NS1Ag). Terdapat 16 subjek DBD I, 21 subjek DBD II, 31 subjek DBD III, dan 2 subjek DBD IV. Dengan menggunakan Uji Analisis Spearman, tidak terdapat korelasi yang signifikan antara nilai positif ∆Hct (hemokonsentrasi) dan tingkat keparahan DBD (r=0,247; p=0,394; CI=95%). Simpulan, perbedaan hematokrit pertama dan kedua pada pemeriksaan hematokrit serial tidak berhubungan dengan keparahan DBD.","PeriodicalId":312900,"journal":{"name":"Global Medical & Health Communication (GMHC)","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130085508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical and Hematological Parameters as the Predictors of Shock in Dengue Infection","authors":"Utami Mulyaningrum, Khairunisa Wardani","doi":"10.29313/GMHC.V6I3.3034","DOIUrl":"https://doi.org/10.29313/GMHC.V6I3.3034","url":null,"abstract":"Dengue infection is one of the main health issues in the world and Asia has the highest incidence of dengue infection with most children aged 5–15 years affected. As World Health Organization (WHO) guidelines recommend, the identification of warning signs at defervescence can detect patients who are at risk of progression to shock. This study aimed to determine the clinical and hematological parameters as the predictors of shock in dengue infection. This retrospective study collected medical records of pediatric patients suffering from dengue infection admitted to dr. Soediran Mangun Sumarso Regional Hospital in Wonogiri, Central Java in January–November 2016. Data was collected in December 2016. The studied predictor factors consisted of clinical and hematological parameters that represented the warning signs of dengue infection. Statistical analysis was performed using the logistic regression test. Of the 110 eligible subjects, 33 (30%) of them suffered from dengue shock syndrome. The multivariate analysis showed that gastrointestinal bleeding (OR=32.62), pleural effusion (OR=31.45), hematocrit >45% (OR=8.67), and thrombocytopenia ≤50,000/µL (OR=13) increased the risk of dengue shock syndrome. Clinical parameters as gastrointestinal bleeding and pleural effusion as well as laboratory parameters of hematocrit and thrombocytopenia became the predictors of shock in dengue infection. PARAMETER KLINIS DAN HEMATOLOGIS SEBAGAI PREDIKTOR KEJADIAN SYOK PADA INFEKSI DENGUE Infeksi dengue merupakan salah satu masalah kesehatan utama di dunia. Asiamerupakan kawasan dengan insidensi infeksi dengue tertinggi dengan penderita terbanyak anak berusia 5–15 tahun. World Health Organization (WHO) menyatakan bahwa tanda bahaya dengue pada fase kritis dapat mendeteksi kejadian syok pada pasien. Tujuan penelitian ini adalah menentukan parameter klinis dan hematologis yang menjadi prediktor syok pada infeksi dengue. Penelitian ini merupakan penelitian retrospektif dengan mengumpulkan data rekam medis pasien anak yang menderita infeksi dengue dan dirawat di RSUD dr. Soediran Mangun Sumarso Wonogiri Jawa Tengah pada Januari–November 2016. Pengambilan data dilakukan pada bulan Desember 2016. Faktor prediktor yang diteliti adalah parameter klinis dan hematologis yang merupakan tanda bahaya infeksi dengue. Analisis statistik dilakukan menggunakan uji regresi logistik. Dari 110 subjek penelitian yang memenuhi kriteria, 33 (30%) di antaranya menderita sindrom syok dengue. Analisis multivariat menunjukkan perdarahan saluran cerna (OR=32,62), efusi pleura (OR=31,45), hematokrit >45% (OR=8,67), dan jumlah trombosit ≤50.000/µL (OR=13) meningkatkan risiko sindrom syok dengue. Parameter klinis berupa perdarahan saluran cerna dan efusi pleura serta parameter laboratoris berupa hematokrit dan jumlah trombositopenia merupakan prediktor kejadian syok pada infeksi dengue.","PeriodicalId":312900,"journal":{"name":"Global Medical & Health Communication (GMHC)","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121960580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Peer Counseling Model in Adolescents Reproductive Health for Senior High School Students","authors":"Indah Nurfazriah, D. Sunjaya, Susi Susanah","doi":"10.29313/GMHC.V6I3.3108","DOIUrl":"https://doi.org/10.29313/GMHC.V6I3.3108","url":null,"abstract":"Premarital sexual behavior in adolescents is at risk of sexual intercourse. One of the teenagers' factors in premarital sexual intercourse is a lack of knowledge about adolescent reproductive health. One method that can be given to increase knowledge about reproductive health is peer counseling. Peer counseling service improvement can be supported by the availability of modules or teaching materials to be used as a guide for peer counselors. The purpose of this study was to analyze the substance of the peer counseling module, analyze the perspective of the prospective module user on the development of peer counseling modules, and develop a model of the peer counseling module. The design of this study was the concurrent mixed method was divided into two stages, namely in-depth interviews with the experts and interviews and surveying with module users. The data was collected from the senior high school students in Cimahi and Bandung, West Java from March to July 2017. The result of this study showed that the substances developed in this module were the adolescents’ reproductive health, adolescents’ preparation in family planning, and adolescents’ ethics. Based on results of the analysis using the Rasch model, in the module user’s perspective, there is a need for the development of peer counseling modules. Evaluation of the module’s model from participants showed that they mostly agreed with the module’s model and the substances that were developed. MODEL MODUL KONSELING SEBAYA DALAM KESEHATAN REPRODUKSI REMAJA PADA SISWA SEKOLAH MENENGAH ATAS Perilaku seksual pranikah pada remaja berisiko melakukan hubungan seksual. Salah satu faktor remaja melakukan hubungan seksual pranikah adalah pengetahuan tentang kesehatan reproduksi remaja yang kurang. Salah satu metode yang dapat diberikan untuk meningkatkan pengetahuan tentang kesehatan reproduksi adalah konseling sebaya. Peningkatan pelayanan konseling sebaya dapat ditunjang oleh ketersediaan modul atau bahan ajar sebagai panduan bagi konselor sebaya. Tujuan penelitian ini adalah menganalisis substansi modul konseling sebaya, menganalisis perspektif pengguna modul tentang pengembangan modul konseling sebaya, dan mengembangkan model modul konseling sebaya. Desain penelitian yang digunakan concurrent mixed methods yang dibagi menjadi dua tahap, yaitu wawancara mendalam dengan para pakar serta wawancara dan survei dengan pengguna modul. Data dikumpulkan dari siswa SMA di Cimahi dan Bandung, Jawa Barat mulai Maret hingga Juli 2017. Hasil penelitian menunjukkan bahwa substansi yang perlu dikembangkan dalam modul konseling sebaya adalah kesehatan reproduksi remaja, persiapan remaja dalam perencanaan keluarga, dan etika remaja. Berdasar atas hasil analisis menggunakan model Rasch, perspektif dari para pengguna modul adalah perlu pengembangan modul konseling sebaya. Evaluasi model modul dari partisipan menunjukkan bahwa kebanyakan mereka setuju dengan model modul dan substansi modul yang dikembangkan.","PeriodicalId":312900,"journal":{"name":"Global Medical & Health Communication (GMHC)","volume":"98 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128393243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antibiotics Used for Upper Respiratory Tract Infection: a Case Study at a Primary Health Center Bogor Indonesia","authors":"Wiwid Ambarwati, V. Setiawaty, A. Wibowo","doi":"10.29313/GMHC.V6I3.3618","DOIUrl":"https://doi.org/10.29313/GMHC.V6I3.3618","url":null,"abstract":"Acute upper respiratory tract infection (URTI) is one of the health problem in a community with high prevalence and healthcare cost. At the primary health center (PHC), URTI is one of the most common diseases with a prevalence 45.64% in Bogor city on 2015, while Basic Health Research 2013 data showed the prevalence of URTI in Indonesia by 25%. This study analyzes the antibiotic prescription for URTI patients, factors influencing the rationale of antibiotic prescriptions, and the rational use of medicine (RUM) program management at Primary Health Centers at Bogor city. The research was analytic descriptive cross-sectional study by collecting data from medical records of patients diagnosed with non-pneumonia URTI, observation for outpatient health care, and interview with all responsible persons. The data were collected on 16 April–20 May 2018 from primary health centers at Bogor city. The samples were 359 oral antibiotic prescriptions of three physicians and antibiotics were prescribed for 122 (34%) cases from 359 cases of which 102 were evaluated for rationality according to local guidelines issued by the Ministry of Health Republic of Indonesia. The URTI diagnosis is classified into few categories with the prevalence of nasopharyngitis (62.9%), pharyngitis (30.6%), tonsillitis (5.3%), and sinusitis and acute otitis media (0.6%). Most antibiotics used were amoxicillin and cefadroxil. This study revealed that antibiotics prescribed 88% inaccuracy of antibiotics duration, 12% incompatibility with the guidance of antibiotic, 3% incompatibility with guidance and imprecise duration, and 1% inaccuracy of dose. Some factors that influencing rationality of antibiotics prescription was lack of physician's adherence to the clinical guideline, pharmacist role was not optimal, and lack of monitoring evaluating. PENGGUNAAN ANTIBIOTIK UNTUK INFEKSI SALURAN PERNAPASAN ATAS: STUDI KASUS DI PUSAT KESEHATAN PRIMER BOGOR INDONESIA Infeksi saluran pernapasan atas (ISPA) akut adalah salah satu masalah kesehatan dengan prevalensi dan biaya perawatan kesehatan yang tinggi. Di pusat kesehatan masyarakat (puskesmas), ISPA adalah salah satu penyakit yang paling umum dengan prevalensi 45,64% di Kota Bogor pada tahun 2015, sementara data Riset Kesehatan Dasar 2013 menunjukkan prevalensi ISPA di Indonesia sebesar 25%. Penelitian ini menganalisis resep antibiotik untuk pasien ISPA, faktor yang memengaruhi dasar pemberian antibiotik, dan penggunaan manajemen program pengobatan rasional di puskesmas di Kota Bogor. Penelitian ini adalah penelitian deskriptif analitik cross-sectional dengan mengumpulkan data rekam medis pasien yang didiagnosis nonpneumonia ISPA, observasi perawatan kesehatan rawat jalan, dan wawancara. Data dikumpulkan pada 16 April–20 May 2018 dari puskesmas di Kota Bogor. Sampel adalah 359 resep antibiotik oral dari tiga dokter dan antibiotik diresepkan untuk 122 (34%) kasus dari 359 kasus yang 102 di antaranya dievaluasi untuk rasionalitas sesuai dengan pedoma","PeriodicalId":312900,"journal":{"name":"Global Medical & Health Communication (GMHC)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129057446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tryando Bhatara, A. Achadiyani, U. Gamayani, Herry Herman
{"title":"Perinatal Al-Quran Sound to Novel Object Recognition Memory and Hippocampal Cell Count","authors":"Tryando Bhatara, A. Achadiyani, U. Gamayani, Herry Herman","doi":"10.29313/GMHC.V6I3.3748","DOIUrl":"https://doi.org/10.29313/GMHC.V6I3.3748","url":null,"abstract":"Al-Quran sound as auditory stimulation may influence the development of systems related to memory. This study aimed to investigate the effect of Al-Quran acoustic stimulation to novel object recognition (NOR) memory and amount of hippocampal formation cells at postnatal day (PND) 21 Wistar rats. This study was conducted in September 2016 to January 2017. Adult Wistar rats divided into intervention and control groups were bred at Faculty of Medicine Universitas Islam Bandung. Rat pups in the intervention group were exposed to Quranic sound from postcoital day 0 to the PND 20. Rats of PND 20 was involved in the NOR test by documenting the value of the duration of exploration of the familiar and novel object. The rats’ brains were extracted and processed at Faculty of Medicine Universitas Padjadjaran for cell counting of hippocampal formation stained with hematoxylin-eosin. The results displayed a higher value of D1 (exploration time difference) and a total number of hippocampal formation cells in the Al-Quran groups. These results can be related to the role of the Quranic voice in suggesting higher learning aspects, activating neurogenesis or cell survival transcription factors. However, there was no difference in discrimination index (DI) value between groups which could be indicating inadequate habituation period, interval, testing age, or stress factors. Numerous limitations from this field of research suggest that the biological role of sound stimulation is still in its early stages of development. In conclusion, exposure to perinatal Al-Quran sound may serve as stimulation which enhances learning, memory, neurogenesis or cell survival of hippocampal formation. SUARA AL-QURAN PERINATAL PADA MEMORI NOVEL OBJECT RECOGNITION DAN JUMLAH SEL HIPOKAMPUSSuara Al-Quran sebagai stimulasi pendengaran diperkirakan dapat memengaruhi perkembangan sistem tubuh terkait memori. Penelitian ini bertujuan mengamati pengaruh stimulasi suara Al-Quran terhadap memori novel object recognition (NOR) dan jumlah sel formasi hipokampus pada tikus Wistar 21 hari setelah lahir (postnatal day/PND). Penelitian ini dilaksanakan pada September 2016 sampai Januari 2017. Tikus Wistar dewasa yang dibagi dalam kelompok perlakuan dan kontrol dibiakkan di Fakultas Kedokteran Universitas Islam Bandung. Anak tikus Wistar dipaparkan dengan suara Al-Quran sejak hari postcoital 0 sampai anak tikus lahir dan berumur 20 hari setelah lahir (PND 20). Tikus PND 20 dilibatkan dalam tes NOR dengan dokumentasi nilai durasi eksplorasi objek lama dan baru. Otak tikus diproses di Fakultas Kedokteran Universitas Padjadjaran untuk penghitungan jumlah sel formasi hipokampus dengan pewarnaan hematoxylin-eosin. Hasil penelitian ini menunjukkan nilai D1 (perbedaan durasi eksplorasi objek lama–baru) dan jumlah sel formasi hipokampus lebih tinggi pada kelompok perlakuan dengan Al-Quran. Hasil tersebut dapat terkait dengan peran suara Al-Quran dalam aktivasi faktor pertumbuhan atau transkripsi. Namun, tidak","PeriodicalId":312900,"journal":{"name":"Global Medical & Health Communication (GMHC)","volume":"68 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128164683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge, Attitude, and Behavior of Indonesian Breastmilk Donors via the Internet","authors":"Iva Septyani, Sri Umijati","doi":"10.29313/GMHC.V6I3.2724","DOIUrl":"https://doi.org/10.29313/GMHC.V6I3.2724","url":null,"abstract":"Breastmilk donors are increasingly widespread and can be done by mothers easily and rapidly through the internet. This study aims to analyze the correlation of knowledge and attitudes of breastmilk donors to the behavior of breastmilk donors via the internet in Indonesia. The study used a cross-sectional analytic design and using a total sampling technique by sending research instruments in the form of the Google form was conducted in January–April 2017. The study respondents were breastmilk donors who posted information on their breastmilk to be shared through Facebook Human Milk 4 Human Babies Indonesia in Jakarta, Depok, Indramayu, Bandung, and others were totaling 41 respondents. Statistical analysis using the Spearman test with confidence level was α=0.05. The study results showed that the correlation to knowledge and behavior of breastmilk donors had p value=0.080, while the correlation on attitude and behavior of breastmilk donors had p value=0.715. In conclusion, there was no correlation between the attitude of breastmilk donors and the practice of breastmilk sharing via the internet. PENGETAHUAN, SIKAP, DAN PERILAKU PENDONOR ASI VIA INTERNET DI INDONESIA Donor air susu ibu (ASI) semakin marak dan dapat dilakukan para ibu dengan mudah dan pesat melalui internet. Penelitian ini bertujuan mengetahui hubungan pengetahuan dan sikap pendonor ASI dengan perilaku donor ASI via internet di Indonesia. Penelitian ini merupakan penelitian desain analitik cross-sectional dan menggunakan teknik total sampling dengan mengirimkan instrumen penelitian dalam bentuk Google form yang dilakukan pada bulan Januari–April 2017. Responden penelitian adalah pendonor ASI yang mem- posting informasi ASI-nya untuk dibagikan melalui Facebook Human Milk 4 Human Babies Indonesia di Jakarta, Depok, Indramayu, Bandung, dan lain-lain yang berjumlah 41 responden. Analisis statistik menggunakan Uji Spearman dengan tingkat kepercayaan α=0,05. Hasil penelitian menunjukkan bahwa hubungan pengetahuan dengan perilaku pendonor ASI memiliki nilai p=0,080, sedangkan hubungan sikap dengan perilaku pendonor ASI memiliki nilai p=0,715. Simpulan, tidak terdapat hubungan pengetahuan dan sikap pendonor ASI dengan perilaku pendonor ASI via internet di Indonesia.","PeriodicalId":312900,"journal":{"name":"Global Medical & Health Communication (GMHC)","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133391818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}