Journal of Clinical Immunology & Microbiology最新文献

{"title":"Cooling the Lower Abdomen for Pain Relief, Boosting the Immune System, Stopping the Hot Fleshes During Menopause and Better Sleep","authors":"Maria Kuman","doi":"10.46889/jcim.2024.5103","DOIUrl":"https://doi.org/10.46889/jcim.2024.5103","url":null,"abstract":"The article is about cooling (with cold water) of the lower abdomen (which is most sensitive to cold) for: relief of abdominal pain, boosting the immune system, handling hot flashes during menopause and better sleep. The article also explains how it works – it is done through the biofield seen as aura, which rules and regulates everything in the body. I found it to be Nonlinear Electromagnetic Field (NEMF), which being nonlinear is not dissipating and can imprint information. The waves of the biofield (aura) scan the new environment and bring the information to the material body telling it how to change to adapt to the new environment. If the environment is drastically new, it handles the evolution to new species. In the process of adaptation, first the biofield (aura) NEMF is changed and if the drastically new environment stays the same for a long time, it evolves into DNA changes and evolution to new species. A proof that the evolution to new species is done through the biofield is the fact that the evolution to new species is done through a quantum jump – there are no intermediate forms.","PeriodicalId":308430,"journal":{"name":"Journal of Clinical Immunology & Microbiology","volume":"111 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140250608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Practices Regarding Helminth Infections: The Study at A District in Ghana","authors":"J. Apenteng","doi":"10.46889/jcim.2024.5102","DOIUrl":"https://doi.org/10.46889/jcim.2024.5102","url":null,"abstract":"Soil Transmitted Helminths Infestations (STHIs) harm both the health and wellbeing of adults and children. Worm infestation can be described as the infection of internal organ tract with any of many species of helminths or parasitic worms such as Ascaris (Round worm), Enterobius (Pin worm), Trichinella spiralis and numerous species of Cestodes (Tape worm). The aim of the study was to obtain the knowledge, perception and practices regarding helminth infections amongst the people of Prampram. This study was a cross-sectional study in which a structured questionnaire was administered by the researchers to obtain socio-demographic data and knowledge regarding the subject matter. The study population involved 400 respondents from Prampram. A random sampling technique was used to select the sample and analysed by SPSS software version 14. Results showed that out of the 400 respondents, 230 males (57.5%) and the rest females, 302 respondents were not married and 290 people (72.5 %) had attained tertiary level of education. There was a higher frequency of the use of worm medication between the ages of 15 and 24 as compared to the other age groups and a greater level of education was associated with a higher level of knowledge of worm- infestation and medication use. Out of the 400 respondents, (362)90.6% had used worm medication before whiles the rest have not. All the respondents had a knowledge of at least one sign or symptom of worm infestation. There was a higher frequency of worm medication use and knowledge of the signs and symptoms of worm infestation between the ages of 15 and 24 years. Majority (36.5%) of the respondents who use worm medication resorted to (Albendazole) in treating worm infestation. There was an observed association between the socio-demographic factors of age and level of education and the knowledge of worm infestation and the practices associated with use of worm medication.","PeriodicalId":308430,"journal":{"name":"Journal of Clinical Immunology & Microbiology","volume":"4 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139591962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Non-Right-Handedness and Multiple Sclerosis (MS)","authors":"Melissa Villafana","doi":"10.46889/jcim.2024.5101","DOIUrl":"https://doi.org/10.46889/jcim.2024.5101","url":null,"abstract":"Background: Only two studies have examined the relationship between handedness and Multiple Sclerosis (MS).\u0000\u0000Objective: To extend previous work examining any relationships between MS and handedness.\u0000\u0000Methods: Using an online survey, self-reported MS individuals with Primary Progressive MS (PPMS) and Relapsing Remitting MS (RRMS) (N = 188) were examined. Handedness was categorized three ways using the Edinburgh Handedness Inventory (1971): Writing Hand, Handedness Direction and Handedness Degree.\u0000\u0000Results: MS Type and Writing Hand was significant such that participants who wrote with their left hand were more likely to be diagnosed with PPMS than participants who wrote with their right hand. MS Type and Handedness Direction was significant such that left-handed women were more likely to be diagnosed with PPMS than right-handed women.\u0000\u0000Conclusion: The current study suggests that there in fact, may be a relationship between MS and handedness, particularly in women.","PeriodicalId":308430,"journal":{"name":"Journal of Clinical Immunology & Microbiology","volume":"27 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139523520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scanning Ion Microscopy and Its Application in Microbiology","authors":"Marlene Benchimol","doi":"10.46889/jcim.2023.4309","DOIUrl":"https://doi.org/10.46889/jcim.2023.4309","url":null,"abstract":"Helium ion microscopy, a scanning microscope operating with ions rather than electrons, is one of the best equipment to analyze the surface of cells and the surface of intracellular compartments exposed by different methods. This short review aims to show the advantages of resolution and depth of focus in some microorganisms such as viruses, bacteria, fungi and parasitic protists.","PeriodicalId":308430,"journal":{"name":"Journal of Clinical Immunology & Microbiology","volume":"116 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139135157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Macrophage Responses Against Acellularized Dermal Matrix from Human Versus Porcine Predicts the In-vivo Fibrosis","authors":"A. Leelahavanichkul","doi":"10.46889/jcim.2023.4308","DOIUrl":"https://doi.org/10.46889/jcim.2023.4308","url":null,"abstract":"Background: Due to the possible difference in the manufacturer’s processes, in-vitro and in-vivo tests might be beneficial for the selection of an Acellularized Dermal Matrix (ADM).\u0000\u0000Methods: ADMs from human and porcine were replaced the mouse skins and tested macrophage reactions using RAW264.7 cells.\u0000\u0000Results: In comparison with porcine ADM, human ADM induced higher reaction and fibrosis on mouse histology at 2 wk (but became similar between groups at 14 wk post-operation) and induced higher upregulation of pro-inflammatory genes at 24 h post-macrophage stimulation.\u0000\u0000Conclusion: Macrophage responses were proposed to use for the prediction of in-vivo ADM responses which might be beneficial for the ADM selection.","PeriodicalId":308430,"journal":{"name":"Journal of Clinical Immunology & Microbiology","volume":"42 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138943640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential Benefits and Challenges of mRNA Cancer Vaccines","authors":"","doi":"10.46889/jcim.2023.4307","DOIUrl":"https://doi.org/10.46889/jcim.2023.4307","url":null,"abstract":"Cancer is a complex and multifaceted disease that affects millions of people worldwide. One of the most promising advances in cancer treatment and prevention is the development of mRNA cancer vaccines. These vaccines are designed to harness the power of the immune system to target and eliminate cancer cells, offering a revolutionary approach to cancer therapy. Recently, one mRNA vaccine (mRNA-4157/v940) received FDA approval to be used as an adjuvant with Pembrolizumab therapy in melanoma patients. In addition, several mRNA cancer vaccines are in the development stage as follows.","PeriodicalId":308430,"journal":{"name":"Journal of Clinical Immunology & Microbiology","volume":"113 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138953914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asia Syndrome and Breast Implants, Report of A Case and Review of The Literature","authors":"Vargas Hernández Víctor Manuel","doi":"10.46889/jcim.2023.4306","DOIUrl":"https://doi.org/10.46889/jcim.2023.4306","url":null,"abstract":"Background: Over the past decades, evidence has accumulated that autoimmune symptoms can be triggered by exposure to environmental immunostimulatory factors that act as adjuvants in genetically susceptible individuals, with several unexplained symptoms. Adjuvant-induced autoimmune/autoinflammatory Syndrome (ASIA) was described in 2011 by Shoenfeld and Agmon-Levin and defined the diagnostic criteria. However, the association of this syndrome with silicone breast implants is controversial.\u0000\u0000Objective: To describe a case of ASIA syndrome in a silicone breast implant carrier and review of the literature.\u0000\u0000Clinical Case: JKT 36-year-old woman with luminal infiltrating ductal carcinoma; with negative extension studies, a conservative mastectomy of the skin and areola was performed with immediate reconstruction with an implant with a breast prosthesis and hormone therapy; Her follow-up was torpid with fatigue, pain in the arm, depression and sleep disturbances and affected breast skin, without infection. As she did not respond to conservative management, it was decided to remove the prosthesis, resection of the capsule and skin, due to the suspicion of the syndrome. From ASIA, as there was no involvement or persistence of breast cancer, with immediate improvement.\u0000\u0000Method: Bibliographic review of original articles written in English on cases of ASIA syndromes, associated with silicone breast implants from their description to the present.\u0000\u0000Results: Until 2019, 126 cases of ASIA syndrome due to silicone breast prostheses and implants were reported. Removal of the prosthesis improves symptoms.\u0000\u0000Conclusion: ASIA syndrome is recent, it is still considered an evolving concept, it is necessary to identify risk factors for the development of autoimmune phenomena in individuals who will receive some type of adjuvant to prevent cases of this syndrome.","PeriodicalId":308430,"journal":{"name":"Journal of Clinical Immunology & Microbiology","volume":" 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138960665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding the Diagnosis of Viral Meningo-Encephalitis in India: A Systematic Review","authors":"S. Amalakanti","doi":"10.46889/jcim.2023.4204","DOIUrl":"https://doi.org/10.46889/jcim.2023.4204","url":null,"abstract":"Background and Objectives: Diagnosis of viral meningoencephalitis is very crucial for recognizing the occurrence of epidemics and for instituting appropriate treatment. The diagnostic capability of the country can be ascertained by studying the published reports of viral meningoencephalitis in our country from reputed scientific literature. Hence, we aimed to study the diagnostic methods used for viral meningo encephalitis from Indian studies indexed in PubMed database.\u0000\u0000Methods: The data was gathered from human studies of actual cases of viral meningitis, encephalitis or meningoencephalitis in India up to 8th August 2016 [earliest study found was from the year 1988] indexed in PubMed database.\u0000\u0000Results: A total of 186 articles were included from 1548 studies screened. Clinical diagnosis over arched all the methods of diagnosis of viral meningoencephalitis in all the studies. Only 23.1% studies reported definitive confirmation of the infectious agent by PCR. Only 34.3% studies reported any microbiological tests for viral etiology. SGPGI, NIV AND NIMHANS were the three major centers reporting molecular diagnosis. Over three decades PCR has superseded antibody testing for viral meningoencephalitis diagnosis.\u0000\u0000Interpretation and Conclusion: Our analysis shows that the diagnosis of viral meningo encephalitis in India is mainly based on clinical diagnosis. Definitive diagnosis by molecular diagnostic methods can be achieved with the establishment of a greater number of molecular viral diagnostic and research labs.","PeriodicalId":308430,"journal":{"name":"Journal of Clinical Immunology & Microbiology","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128247110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Narrative Review on Argentine Hemorrhagic Fever: Junin Virus (JUNV)","authors":"Sadia Afrin","doi":"10.46889/jcim.2023.4202","DOIUrl":"https://doi.org/10.46889/jcim.2023.4202","url":null,"abstract":"Epidemic cases of Argentine hemorrhagic fever (also known as AHF) have been associated with the Junin virus, also known as JUNV, ever since the 1950s. The JUNV arenavirus is endemic to the countries of the New World. In this study, we will attempt to communicate the current level of knowledge on the morphology, transmission, replication and epidemiology of the Junin virus (JUNV). We examined both PubMed and Google Scholar in order to discover the most recent research on the Junin virus. The virus is indigenous to the humid pampas of Argentina, where it is propagated by the aerosolization of host rodent excrement. In recent years, considerable advances have been made as new technologies have increased understanding of how the Junn virus replicates. We will focus on recent studies that aim to understand the attenuation of viruses by examining their biological mechanisms. We will also provide a brief overview of what is currently known about the pathogenesis of the Junn virus, with an emphasis on treatments, morphology, transmission, replication and epidemiology.","PeriodicalId":308430,"journal":{"name":"Journal of Clinical Immunology & Microbiology","volume":"17 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131840666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Antibiotic Resistance in Pediatric Patients Suffering from Cancer","authors":"A. Akhtar","doi":"10.46889/jcim.2023.4203","DOIUrl":"https://doi.org/10.46889/jcim.2023.4203","url":null,"abstract":"Introduction: The discovery of antibiotics has revolutionized the field of healthcare since many lethal infections which were previously impossible to treat are now have become much curable. However, a high reliance of the clinicians on antibiotics have led to their irrational use which has given rise to a serious problem in the form of Antimicrobial Resistance (AMR) a phenomenon where the microbes develop the capacity to neutralize the antimicrobial capacity of the antibiotics. In cancer patient AMR is not so frequent as compared to other patients who suffer from infectious diseases but still if cancer patients during their chemotherapy encounter the issue of AMR their cancer treatment becomes highly challenging.\u0000\u0000Objective: To evaluate the prevalence of AMR in the cancer affected pediatric patients being treated with antibiotics.\u0000\u0000Materials and Methods: In this cross-sectional study 300 pediatric patients who received prescriptions with at least one antibiotic suffering from cancer and were treated with at least one antibiotic were included. The data was collected with the consent of their guardians from the cancer ward of The Children’s hospital and The Institute of Child Health, Lahore, Pakistan by utilizing non-probability sampling technique (convenient sampling) for the period of 6-months.\u0000\u0000Results: The study findings depicted that the children aged between 4 to 7 years got affected by various cancers and lymphoblastic leukemia (47%) was the most frequently occurring cancer. Urine, blood and mucosal swabs were used for sampling but majority of the samples were the blood (29%) samples that were used to detect the occurrence of AMR. It was observed that the study population was more susceptible to gram-negative bacteria than gram-positive bacteria. The incidence of AMR was higher in gram-negative bacteria than that of gram-positive bacteria. Among the collected samples the bacteria showed sensitivity for ciprofloxacin (23%), amikacin (21%), piperacillin (24%) and ceftazidime (23%). Considering the resistance patterns among the tested antibiotics that were prescribed to the cancer patients various penicillin antibiotics and ceftazidime showed a higher incidence of the AMR.\u0000\u0000Conclusion: The AMR is a serious problem that is encountered during the treatment of infections in the pediatric patients affected by cancer thus, the appropriate selection of antibiotics by the clinicians is a matter of serious concern so as to prevent AMR and to obtain maximum therapeutic outcomes of the chemotherapy.","PeriodicalId":308430,"journal":{"name":"Journal of Clinical Immunology & Microbiology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123829188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}