A Narrative Review on Argentine Hemorrhagic Fever: Junin Virus (JUNV)

Abstract

Epidemic cases of Argentine hemorrhagic fever (also known as AHF) have been associated with the Junin virus, also known as JUNV, ever since the 1950s. The JUNV arenavirus is endemic to the countries of the New World. In this study, we will attempt to communicate the current level of knowledge on the morphology, transmission, replication and epidemiology of the Junin virus (JUNV). We examined both PubMed and Google Scholar in order to discover the most recent research on the Junin virus. The virus is indigenous to the humid pampas of Argentina, where it is propagated by the aerosolization of host rodent excrement. In recent years, considerable advances have been made as new technologies have increased understanding of how the Junn virus replicates. We will focus on recent studies that aim to understand the attenuation of viruses by examining their biological mechanisms. We will also provide a brief overview of what is currently known about the pathogenesis of the Junn virus, with an emphasis on treatments, morphology, transmission, replication and epidemiology.