{"title":"mRNA 癌症疫苗的潜在优势与挑战","authors":"","doi":"10.46889/jcim.2023.4307","DOIUrl":null,"url":null,"abstract":"Cancer is a complex and multifaceted disease that affects millions of people worldwide. One of the most promising advances in cancer treatment and prevention is the development of mRNA cancer vaccines. These vaccines are designed to harness the power of the immune system to target and eliminate cancer cells, offering a revolutionary approach to cancer therapy. Recently, one mRNA vaccine (mRNA-4157/v940) received FDA approval to be used as an adjuvant with Pembrolizumab therapy in melanoma patients. In addition, several mRNA cancer vaccines are in the development stage as follows.","PeriodicalId":308430,"journal":{"name":"Journal of Clinical Immunology & Microbiology","volume":"113 2","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Potential Benefits and Challenges of mRNA Cancer Vaccines\",\"authors\":\"\",\"doi\":\"10.46889/jcim.2023.4307\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Cancer is a complex and multifaceted disease that affects millions of people worldwide. One of the most promising advances in cancer treatment and prevention is the development of mRNA cancer vaccines. These vaccines are designed to harness the power of the immune system to target and eliminate cancer cells, offering a revolutionary approach to cancer therapy. Recently, one mRNA vaccine (mRNA-4157/v940) received FDA approval to be used as an adjuvant with Pembrolizumab therapy in melanoma patients. In addition, several mRNA cancer vaccines are in the development stage as follows.\",\"PeriodicalId\":308430,\"journal\":{\"name\":\"Journal of Clinical Immunology & Microbiology\",\"volume\":\"113 2\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-12-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Clinical Immunology & Microbiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.46889/jcim.2023.4307\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Immunology & Microbiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46889/jcim.2023.4307","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
癌症是一种复杂的多发性疾病，影响着全球数百万人。mRNA 癌症疫苗的开发是癌症治疗和预防领域最有希望的进展之一。这些疫苗旨在利用免疫系统的力量来靶向消除癌细胞，为癌症治疗提供了一种革命性的方法。最近，一种 mRNA 疫苗（mRNA-4157/v940）获得了 FDA 批准，可作为 Pembrolizumab 治疗黑色素瘤患者的辅助药物。此外，还有以下几种 mRNA 癌症疫苗正处于开发阶段。
Potential Benefits and Challenges of mRNA Cancer Vaccines
Cancer is a complex and multifaceted disease that affects millions of people worldwide. One of the most promising advances in cancer treatment and prevention is the development of mRNA cancer vaccines. These vaccines are designed to harness the power of the immune system to target and eliminate cancer cells, offering a revolutionary approach to cancer therapy. Recently, one mRNA vaccine (mRNA-4157/v940) received FDA approval to be used as an adjuvant with Pembrolizumab therapy in melanoma patients. In addition, several mRNA cancer vaccines are in the development stage as follows.
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