Annals of Tropical Pathology最新文献

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Nephroprotective effect of Citrus sinensis L. on mercury exposed wistar rats 柑桔对汞暴露wistar大鼠的肾保护作用
Annals of Tropical Pathology Pub Date : 2020-07-01 DOI: 10.4103/atp.atp_42_20
Washima Amber, S. Musa, S. Sambo, A. Agbon
{"title":"Nephroprotective effect of Citrus sinensis L. on mercury exposed wistar rats","authors":"Washima Amber, S. Musa, S. Sambo, A. Agbon","doi":"10.4103/atp.atp_42_20","DOIUrl":"https://doi.org/10.4103/atp.atp_42_20","url":null,"abstract":"Context: Exposure to all forms of mercury has toxic effect on several biosystems. Disruption in structural, biochemical, and physiological renal integrity results in nephrotoxicity. Citrus sinensis L (sweet orange) has medicinal benefits for diverse ailments. Aim: This study evaluated the nephroprotective effect of ethanol fruit peel extract of C. sinensis (EPCS) against mercuric chloride (HgCl2)-triggered nephrotoxicity in Wistar rats. Materials and Methods: Twenty-five Wistar rats (150–180 g) were separated into five Groups (I-V, n = 5): Group I received normal saline (1 ml/kg); Group II received HgCl2 (5 mg/kg); Group III received reference drug, silymarin (100 mg/kg) +HgCl2(5 mg/kg); Group IV received EPCS (750 mg/kg) +HgCl2 (5 mg/kg); and Group V received EPCS (1250 mg/kg) +HgCl2 (5 mg/kg). Treatments were for 14 days. Nephroprotective effect was evaluated using the biochemical assay for renal function, histological, and histochemical assessments using H and E and periodic acid Schiff (PAS) stains and quantification of PAS staining intensity using Imagej® NIH, US. Statistical Analysis Used: One-way analysis of variance with Tukey post hoc test. Results: The results revealed remarkable (P < 0.05) alterations in renal functional biomarkers, especially urea, creatinine, and Na + in HgCl2-treated group compared to the controls. However, EPCS treatment ameliorated alterations comparable to the silymarin and control groups. Histological and histochemical examinations revealed severe distortions in renal histoarchitecture such as shrunken glomerulus and Bowman-space dilatation for the rats exposed to HgCl2 compared to controls. However, EPCS treatment ameliorated distortions by the preservation of renal histoarchitecture comparable to the silymarin and control groups. No remarkable difference for PAS staining intensity relative to controls. Conclusion: EPCS possesses potential nephroprotective effect against mercuric chloride-induced toxicity in Wistar rats.","PeriodicalId":307224,"journal":{"name":"Annals of Tropical Pathology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133515758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Evaluation of lipid profile pattern among apparently healthy students of Niger Delta University 尼日尔三角洲大学表面健康学生血脂形态的评价
Annals of Tropical Pathology Pub Date : 2020-07-01 DOI: 10.4103/atp.atp_17_20
B. Kasia, Victoria Nyondia, Promise Oseajeh, P. Prophet
{"title":"Evaluation of lipid profile pattern among apparently healthy students of Niger Delta University","authors":"B. Kasia, Victoria Nyondia, Promise Oseajeh, P. Prophet","doi":"10.4103/atp.atp_17_20","DOIUrl":"https://doi.org/10.4103/atp.atp_17_20","url":null,"abstract":"Background: Dyslipidemia constitutes a high risk of cardiovascular disease. Aim: This study was designed to evaluate the lipid profile pattern of apparently healthy students of Niger Delta University to detect any possible abnormality. Setting and Design: This was a cross-sectional descriptive study. Materials and Methods: A total of 102 apparently healthy students were studied. A convenient sampling technique was employed for willing participants. The studied group constituted 55 males and 47 females aged within 20–40 years. Relevant demographic data were obtained by a one-on-one interview with the participants. A blood specimen was collected for measurements of total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-c), and low-density lipoprotein cholesterol (LDL-c) by standard assay methods. The data obtained were analyzed using SPSS 22.0, and the student t -test was performed at P < 0.05 for comparison of means. Results: The mean plasma TC and LDL-c values for males were significantly lower than females values of 3.865 ± 0.675 mmol/L versus 4.251 ± 0.851 mmol/L and 2.38 ± 0.49 versus 2.64 ± 0.64 with P = 0.012 and 0.023, respectively. Similarly, the mean plasma HDL-c and TGs for males were lower than female values of 1.126 ± 0.190 mmol/L versus 1.194 ± 0.224 mmol/L and 0.77 ± 0.20 versus 0.82 ± 0.27 with P = 0.099 and 0.27, respectively which were not statistically significant. The age group of 24–27 years constituted the highest mean values and the age group of 28–40 years constituted the least mean values for all the studied parameters. These values, however, did not differ statistically. Most of the participants had significantly within low-normal reference range values. Conclusion: These findings revealed within normal lipid profiles for most subjects.","PeriodicalId":307224,"journal":{"name":"Annals of Tropical Pathology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129792592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extranodal sinonasal rosai-dorfman disease in a Nigerian woman: A case report and review of literature 结外鼻窦玫瑰-多夫曼病1例尼日利亚妇女:1例报告及文献复习
Annals of Tropical Pathology Pub Date : 2020-07-01 DOI: 10.4103/atp.atp_37_20
A. Ajiya, E. Kolo, I. Shuaibu
{"title":"Extranodal sinonasal rosai-dorfman disease in a Nigerian woman: A case report and review of literature","authors":"A. Ajiya, E. Kolo, I. Shuaibu","doi":"10.4103/atp.atp_37_20","DOIUrl":"https://doi.org/10.4103/atp.atp_37_20","url":null,"abstract":"Rosai Dorfman disease (RDD) also referred to as sinus histiocytosis with massive lymphadenopathy is a rare non-neoplastic lymphoproliferative disease with unknown etiology and pathogenesis first described by Rosai and Dorfman in 1969. It is characterized by histiocytic proliferation of lymphatic sinuses, which primarily involves the lymph nodes, but has an extranodal tendency. Frequently encountered extranodal sites in the head-and-neck region is paranasal sinuses and nasal cavity, orbit, parotid gland, and middle ear. We present a case of RDD occurring in the nasal cavity of a 28-year-old female from Nigeria. RDD should be considered a differential diagnosis in any patient with benign sinonasal mass especially arising from the nasal septum with massive cervical lymphadenopathy.","PeriodicalId":307224,"journal":{"name":"Annals of Tropical Pathology","volume":"109 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123141582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bladder diseases: A histopathological study 膀胱疾病:组织病理学研究
Annals of Tropical Pathology Pub Date : 2020-07-01 DOI: 10.4103/atp.atp_33_20
B. Duduyemi, W. Ayibor, R. Azorliade, F. Safo, E. Owusu
{"title":"Bladder diseases: A histopathological study","authors":"B. Duduyemi, W. Ayibor, R. Azorliade, F. Safo, E. Owusu","doi":"10.4103/atp.atp_33_20","DOIUrl":"https://doi.org/10.4103/atp.atp_33_20","url":null,"abstract":"Background: There is a dearth of publications on the histopathological findings from the bladder specimen in this country. Knowledge of the profile of histological findings from bladder biopsies will help reveal the most common lesions, the demographical distribution as well as the association of clinical symptoms with various conditions and interventions to be made. Methodology: This was a retrospective, histopathological study conducted over a period of 10 years. Demographics of the patient were abstracted, and slides were reviewed to establish the diagnoses on bladder biopsies. Results: There were 180 cases of bladder lesions studied. Males accounted for 86 (47.78%), and females recorded 94 (52.22%) of the cases. The modal age group is 50–59, with 42 cases. The mean age is 54.14 ± 18.62. Inflammatory (nonneoplastic) lesions accounted for 53 (29.44%) and neoplastic lesions accounted for 127 (70.56%), of which benign lesions (squamous papilloma) were 13 (10.24%) whereas malignant cases were 114 (89.76%). Urothelial carcinoma of the bladder was the most common bladder malignancy (57%) and squamous cell carcinoma (35.96%). Lymphoma, rhabdomyosarcoma, carcinoma in situ, and adenocarcinoma were relatively rare. Most of the tumors were high grade. Conclusion: Bladder diseases are more common in females in our center, and most of the neoplastic lesions are high-grade carcinomas.","PeriodicalId":307224,"journal":{"name":"Annals of Tropical Pathology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121209263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Seroprevalence and factors associated with risk of human brucellosis among febrile patients attending health-care facilities in Bauchi, North-Eastern Nigeria 尼日利亚东北部包奇卫生保健机构发热患者的人间布鲁氏菌病血清阳性率和与风险相关的因素
Annals of Tropical Pathology Pub Date : 2020-07-01 DOI: 10.4103/atp.atp_39_20
H. Halilu, F. Giwa, Saad A Ahmed, M. Sufiyan, A. Mohammed
{"title":"Seroprevalence and factors associated with risk of human brucellosis among febrile patients attending health-care facilities in Bauchi, North-Eastern Nigeria","authors":"H. Halilu, F. Giwa, Saad A Ahmed, M. Sufiyan, A. Mohammed","doi":"10.4103/atp.atp_39_20","DOIUrl":"https://doi.org/10.4103/atp.atp_39_20","url":null,"abstract":"Background: Brucellosis is a neglected underdiagnosed zoonotic disease of worldwide distribution with varying symptoms similar to those occurring in other febrile illnesses. A recent screening survey conducted among butchers in Bauchi state reported a high prevalence of human brucellosis; however, its burden among patients with other febrile illnesses is unknown. We determine the seroprevalence and factors associated with risk of brucellosis among febrile patients attending health-care facilities (HCFs) in Bauchi metropolis, North-Eastern Nigeria. Methodology: We conducted a hospital-based descriptive cross-sectional study of 382 participants using a multistage sampling technique. Brucella antibodies were detected using Rose Bengal plate test, and a questionnaire was used to identify risk factors associated with human brucellosis. Data analyses were conducted using Epi Info version 7.0. Bivariate and multivariate analyses were conducted at P = 0.05. Results: Fifty-seven (14.9%) of the 382 febrile patients tested had Brucella antibodies. Males: female ratio was 1.1:1, and the mean age was 29.9 (standard deviation ± 12.03). Age, sex, occupational status, keeping animals, having ever milked an animal, handling animals during birth, and consuming unpasteurized milk or meat were found to be significantly associated with brucellosis on bivariate analysis. Conclusions: Up to 14.9% of the febrile patients attending HCFs in Bauchi metropolis had Brucella antibodies. Age, occupational status, consuming unpasteurized milk or meat, handling animals during birth, and lack of awareness on zoonosis remained independent predictors for brucellosis. Therefore, conducting routine serological screening tests for Brucella antibodies in all febrile patients presenting to HCFs will assist in its diagnosis and proper management.","PeriodicalId":307224,"journal":{"name":"Annals of Tropical Pathology","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127680531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Aqueous beetroot juice extract improves renal function and some biochemical parameters in carbon tetrachloride-induced toxicity in sprague dawley rats 甜菜根汁提取物可改善四氯化碳毒性大鼠的肾功能和一些生化指标
Annals of Tropical Pathology Pub Date : 2020-07-01 DOI: 10.4103/atp.atp_38_20
F. Olumese, H. Oboh
{"title":"Aqueous beetroot juice extract improves renal function and some biochemical parameters in carbon tetrachloride-induced toxicity in sprague dawley rats","authors":"F. Olumese, H. Oboh","doi":"10.4103/atp.atp_38_20","DOIUrl":"https://doi.org/10.4103/atp.atp_38_20","url":null,"abstract":"Background: The ability of plant extracts to improve toxicity in the kidney is gaining attention. This may be due to the untoward effects and high cost of orthodox drugs used for the management of kidney disease, therefore, the use of aqueous beetroot juice as a potential ameliorative agent was evaluated. Materials and Methods: Group 1 received 2 ml/kg distilled water (normal control); Group II received 2 ml/kg olive oil; Group III received 2 ml/kg carbon tetrachloride (CCl4) in olive oil 48 hourly (negative control); Group IV received 2 ml/kg CCl4 in olive oil and 250 mg/kg of beetroot/day; Group V received 2 ml/kg CCl4 in olive oil and 500 mg/kg of beetroot/day; and Group VI received 2 ml/kg CCl4 in olive oil and 100 mg/kg silymarin/day (positive control) for 14 days. Animals were euthanized, and blood was collected for the evaluation of electrolytes, urea, and creatinine, whereas the kidney tissue was assessed for histopathological changes. Results: There was a significant (P < 0.05) decrease in the level of K + in the group of rats administered 250 mg and 500 mg/kg of aqueous beetroot extract, when compared to negative control. The levels of Na + were reduced in the treated groups when compared to normal control. There were no significant changes in Cl − levels in all the group of animals. The urea levels decreased in the groups treated with extract or silymarin, and a similar trend of creatinine was observed in the groups administered beetroot extract. However, creatinine concentration was significantly (P < 0.05) increased in the group of rats administered only silymarin when compared to other groups. Histopathological evaluation revealed that the tubular necrosis observed in the kidney was ameliorated after beetroot juice administration. Conclusion: Beetroot juice showed nephroprotective effects against CCl4-induced renal toxicity.","PeriodicalId":307224,"journal":{"name":"Annals of Tropical Pathology","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126389888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sinonasal tuberculosis mimicking malignancy – Case report and review of literature 模拟恶性鼻结核病例报告及文献复习
Annals of Tropical Pathology Pub Date : 2020-01-01 DOI: 10.4103/atp.atp_27_19
S. Muhammad, A. Sule, G. Wey
{"title":"Sinonasal tuberculosis mimicking malignancy – Case report and review of literature","authors":"S. Muhammad, A. Sule, G. Wey","doi":"10.4103/atp.atp_27_19","DOIUrl":"https://doi.org/10.4103/atp.atp_27_19","url":null,"abstract":"Primary sinonasal tuberculosis (TB) is a rare form of TB even in developing countries where TB is prevalent, as it usually results from primary foci elsewhere in the body. It often poses a diagnostic dilemma. There are a few reported cases of primary sinonasal TB in literature. The aim of this study is to report another case of primary sinonasal TB. A 27-year-old female presented with 5 months history of nasal blockade and epistaxis. There was no history of cough, night sweat, malaise, anorexia, weight loss, or fever. Examination revealed a mass in the left nasal cavity extending up to the nasopharynx with contact bleeding. Computerized tomography scan showed a hyperdense lesion, suspected to be a tumor, involving the nasal septum and filling the entire left maxillary sinus with bony destruction of the anterolateral, posterior and medial walls. Chest X-ray, retroviral screening, and other biochemical results were essentially normal. The lesion was excised through lateral rhinotomy, and histology revealed sinonasal TB. Primary sinonasal TB is seldomly seen, meticulous and high index of suspicion in the context of clinical, radiological, and pathological characteristics remain paramount and critical in making an otherwise challenging diagnosis.","PeriodicalId":307224,"journal":{"name":"Annals of Tropical Pathology","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126857129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurocysticercosis in a 14-year-old Nigerian: A case report and review of the literature 尼日利亚14岁神经囊虫病1例报告及文献复习
Annals of Tropical Pathology Pub Date : 2020-01-01 DOI: 10.4103/atp.atp_12_20
S. Soyemi, C. Akinbo, Mgbehoma Ai, F. Emiogun, O. Adegboyega, J. Obafunwa
{"title":"Neurocysticercosis in a 14-year-old Nigerian: A case report and review of the literature","authors":"S. Soyemi, C. Akinbo, Mgbehoma Ai, F. Emiogun, O. Adegboyega, J. Obafunwa","doi":"10.4103/atp.atp_12_20","DOIUrl":"https://doi.org/10.4103/atp.atp_12_20","url":null,"abstract":"Neurocysticercosis (NCC), an infection of the brain by the larval form of Taenia solium tapeworm, has been described as the most common cause of acquired adult seizure and epilepsy in regions of the world where the worm infestation is endemic. It is acquired following ingestion of raw or partially cooked pork-containing cysts of T. solium. We report the case of a 14-year-old male patient, who presented with recurrent tonic–clonic partial seizures of 3 months duration, seizures, and progressive weakness of the left limb, while being fully conscious. He had a left facioparesis of the upper motor neuron type with plastic left hemiparesis. An impression of a right frontal cortical lesion was made. The laboratory investigations as well as the chest radiograph were reported as being essentially unremarkable. The magnetic resonance image of the brain revealed a circumscribed right parietal lesion which was circumscribed. A provisional diagnosis of intracranial tumor was then made. Surgery involved an en bloc resection of a cystic right parietal mass. The gelatinous fluid contained within was submitted for cytological examination. The latter revealed the presence of a cysticercus comprising the scolex, spiral canal, and the bladder wall. A diagnosis of NCC was made, and the patient was thereafter commenced on antihelminthics. The patient made an appreciable recovery thereafter. This report is to emphasize the continued existence of this disease, the need to improve diagnostic suspicion, and skill. This report further supports the proposal to declare NCC an international reportable disease.","PeriodicalId":307224,"journal":{"name":"Annals of Tropical Pathology","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129476002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Clinicopathological characteristics of benign prostatic hyperplasia and prostate cancer in a University Teaching Hospital in Nigeria 尼日利亚某大学教学医院良性前列腺增生和前列腺癌的临床病理特点
Annals of Tropical Pathology Pub Date : 2020-01-01 DOI: 10.4103/atp.atp_18_20
M. Tolani, A. Khalifa, A. Afolayan
{"title":"Clinicopathological characteristics of benign prostatic hyperplasia and prostate cancer in a University Teaching Hospital in Nigeria","authors":"M. Tolani, A. Khalifa, A. Afolayan","doi":"10.4103/atp.atp_18_20","DOIUrl":"https://doi.org/10.4103/atp.atp_18_20","url":null,"abstract":"Introduction: Benign prostatic hyperplasia and prostate cancer are common pathologies of the prostate which could lead to morbidity and quality of life problems in urological patients. The study aimed to determine and compare the demographic, clinical, and pathologic characteristics of patients histologically diagnosed with these pathologies in our center. Methods: This was a prospective study carried out in 105 consecutive patients with the histological diagnosis of benign prostatic hyperplasia or prostate cancer over a period of 1 year. Information on demographic details, clinical presentation, prostate volume, prostate-specific antigen level, and histopathologic data was obtained. Data were analyzed using the Statistical Package for the Social Sciences with P < 0.05 considered statistically significant. Results: Benign prostatic hyperplasia and prostate cancer were diagnosed in 71.4% and 28.6% of the patients, respectively. Patients with prostate cancer had a significantly higher prostate-specific antigen (P = 0.001) and prostate volume (P = 0.005) than those with benign prostatic hyperplasia. Difficulty in urination was the most common presenting symptom in both pathologies (90% vs. 92%, P = 0.713), whereas the occurrence of erectile dysfunction was significantly higher in patients with prostate cancer (50% vs. 24%, P = 0.010). The mean Gleason's score in the patients was 7, and the majority of the prostate cancer patients (96.7%) had advanced disease. There was associated histologic prostatitis in 10.7% of patients with nodular hyperplasia. Conclusion: Benign prostatic hyperplasia is more commonly diagnosed than prostate cancer in our center. Except for erectile dysfunction, the burden of other complications is similar in these patients. There is the need for community advocacy to encourage early presentation in those with lower literacy level, especially patients with prostate cancer, in order to reduce the morbidities associated with the disease.","PeriodicalId":307224,"journal":{"name":"Annals of Tropical Pathology","volume":"129 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126200612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Hemorrhagic infarction of hyperreactio luteinalis in spontaneously conceived singleton pregnancy: An uncommon cause of late third-trimester ovarian accident 自发性单胎妊娠中黄体高反应性出血性梗死:妊娠晚期卵巢意外的罕见原因
Annals of Tropical Pathology Pub Date : 2020-01-01 DOI: 10.4103/atp.atp_37_19
B. Kabir, A. Liman, S. Abdullahi, Stephen Ajani, M. Abubakar, Z. Adamu
{"title":"Hemorrhagic infarction of hyperreactio luteinalis in spontaneously conceived singleton pregnancy: An uncommon cause of late third-trimester ovarian accident","authors":"B. Kabir, A. Liman, S. Abdullahi, Stephen Ajani, M. Abubakar, Z. Adamu","doi":"10.4103/atp.atp_37_19","DOIUrl":"https://doi.org/10.4103/atp.atp_37_19","url":null,"abstract":"Ovarian masses complicate about 1%–2% of all pregnancies while posing diagnostic and therapeutic challenges. Most are benign tumors but occasionally, functional cysts, such as theca lutein cysts, may be encountered in pregnancy. These are bilateral ovarian masses associated with high levels of β-human chorionic gonadotropin, thus seen mostly in the settings of trophoblastic diseases, multiple gestations, or following treatment for subfertility. It has also been reported in spontaneous singleton pregnancies. Clinical presentation is variable, ranging from asymptomatic conditions discovered incidentally to acute gynecological emergencies due to ovarian accidents. We report the case of a 29-year-old gravida 2, para 1 + 0, with estimated gestational age of 39 weeks plus 1 day, who had a previous emergency lower segment cesarean section (ELSCS) 3 years ago and presented with 1-h history of sudden-onset, sharp, right-sided, abdominal pain of increasing intensity. There were no history of trauma and no evidence of labor. On examination, she was a young gravid woman, at term, in severe painful distress. Baseline investigations were done, and she had ELSCS and exploratory laparotomy with a right salpingo-oophorectomy for twisted and hemorrhagic right adnexa discovered. Pathologic evaluation of the right ovary revealed an enlarged, dark brown, lobulated ovarian mass comprising multiple cortical cysts separated by a thin wall and containing dark brown fluid, with gray brown and hemorrhagic solid areas. A histologic diagnosis of hemorrhagic infarction on the background of multiple theca lutein cysts in pregnancy was made. She had a good postoperative recovery.","PeriodicalId":307224,"journal":{"name":"Annals of Tropical Pathology","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114537518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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