Bladder diseases: A histopathological study

Abstract

Background: There is a dearth of publications on the histopathological findings from the bladder specimen in this country. Knowledge of the profile of histological findings from bladder biopsies will help reveal the most common lesions, the demographical distribution as well as the association of clinical symptoms with various conditions and interventions to be made. Methodology: This was a retrospective, histopathological study conducted over a period of 10 years. Demographics of the patient were abstracted, and slides were reviewed to establish the diagnoses on bladder biopsies. Results: There were 180 cases of bladder lesions studied. Males accounted for 86 (47.78%), and females recorded 94 (52.22%) of the cases. The modal age group is 50–59, with 42 cases. The mean age is 54.14 ± 18.62. Inflammatory (nonneoplastic) lesions accounted for 53 (29.44%) and neoplastic lesions accounted for 127 (70.56%), of which benign lesions (squamous papilloma) were 13 (10.24%) whereas malignant cases were 114 (89.76%). Urothelial carcinoma of the bladder was the most common bladder malignancy (57%) and squamous cell carcinoma (35.96%). Lymphoma, rhabdomyosarcoma, carcinoma in situ, and adenocarcinoma were relatively rare. Most of the tumors were high grade. Conclusion: Bladder diseases are more common in females in our center, and most of the neoplastic lesions are high-grade carcinomas.