Sinonasal tuberculosis mimicking malignancy – Case report and review of literature

S. Muhammad, A. Sule, G. Wey
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Abstract

Primary sinonasal tuberculosis (TB) is a rare form of TB even in developing countries where TB is prevalent, as it usually results from primary foci elsewhere in the body. It often poses a diagnostic dilemma. There are a few reported cases of primary sinonasal TB in literature. The aim of this study is to report another case of primary sinonasal TB. A 27-year-old female presented with 5 months history of nasal blockade and epistaxis. There was no history of cough, night sweat, malaise, anorexia, weight loss, or fever. Examination revealed a mass in the left nasal cavity extending up to the nasopharynx with contact bleeding. Computerized tomography scan showed a hyperdense lesion, suspected to be a tumor, involving the nasal septum and filling the entire left maxillary sinus with bony destruction of the anterolateral, posterior and medial walls. Chest X-ray, retroviral screening, and other biochemical results were essentially normal. The lesion was excised through lateral rhinotomy, and histology revealed sinonasal TB. Primary sinonasal TB is seldomly seen, meticulous and high index of suspicion in the context of clinical, radiological, and pathological characteristics remain paramount and critical in making an otherwise challenging diagnosis.
模拟恶性鼻结核病例报告及文献复习
即使在结核病流行的发展中国家,原发性鼻窦炎也是一种罕见的结核病,因为它通常是由身体其他部位的原发性灶引起的。这通常会使诊断陷入困境。文献中报道了一些原发性鼻窦结核病例。本研究的目的是报告另一例原发性鼻窦结核。27岁女性,有5个月的鼻阻塞和鼻出血史。无咳嗽、盗汗、不适、厌食、体重减轻、发热史。检查发现左鼻腔肿块延伸至鼻咽部并接触性出血。计算机断层扫描显示一高密度病变,怀疑为肿瘤,累及鼻中隔,充满整个左上颌窦,前外侧、后壁和内侧壁骨质破坏。胸部x光、逆转录病毒筛查和其他生化结果基本正常。通过侧鼻切开术切除病变,组织学显示为鼻窦结核。原发性鼻窦结核是罕见的,在临床、放射学和病理特征的背景下,细致和高度怀疑的指数仍然是至关重要的,在做出其他具有挑战性的诊断时至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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