Evaluation of lipid profile pattern among apparently healthy students of Niger Delta University

B. Kasia, Victoria Nyondia, Promise Oseajeh, P. Prophet
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Abstract

Background: Dyslipidemia constitutes a high risk of cardiovascular disease. Aim: This study was designed to evaluate the lipid profile pattern of apparently healthy students of Niger Delta University to detect any possible abnormality. Setting and Design: This was a cross-sectional descriptive study. Materials and Methods: A total of 102 apparently healthy students were studied. A convenient sampling technique was employed for willing participants. The studied group constituted 55 males and 47 females aged within 20–40 years. Relevant demographic data were obtained by a one-on-one interview with the participants. A blood specimen was collected for measurements of total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-c), and low-density lipoprotein cholesterol (LDL-c) by standard assay methods. The data obtained were analyzed using SPSS 22.0, and the student t -test was performed at P < 0.05 for comparison of means. Results: The mean plasma TC and LDL-c values for males were significantly lower than females values of 3.865 ± 0.675 mmol/L versus 4.251 ± 0.851 mmol/L and 2.38 ± 0.49 versus 2.64 ± 0.64 with P = 0.012 and 0.023, respectively. Similarly, the mean plasma HDL-c and TGs for males were lower than female values of 1.126 ± 0.190 mmol/L versus 1.194 ± 0.224 mmol/L and 0.77 ± 0.20 versus 0.82 ± 0.27 with P = 0.099 and 0.27, respectively which were not statistically significant. The age group of 24–27 years constituted the highest mean values and the age group of 28–40 years constituted the least mean values for all the studied parameters. These values, however, did not differ statistically. Most of the participants had significantly within low-normal reference range values. Conclusion: These findings revealed within normal lipid profiles for most subjects.
尼日尔三角洲大学表面健康学生血脂形态的评价
背景:血脂异常是心血管疾病的高危因素。目的:本研究旨在评估表面健康的尼日尔三角洲大学学生的血脂特征,以发现任何可能的异常。环境与设计:这是一项横断面描述性研究。材料与方法:对102名表面健康的大学生进行研究。对有意愿的参与者采用了方便的抽样技术。研究对象为男性55人,女性47人,年龄在20-40岁之间。通过与参与者的一对一访谈获得相关人口统计数据。采集血样,用标准测定方法测定总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-c)和低密度脂蛋白胆固醇(LDL-c)。所得资料采用SPSS 22.0进行分析,均数比较采用P < 0.05的学生t检验。结果:男性血浆TC和LDL-c均值分别为3.865±0.675 mmol/L和4.251±0.851 mmol/L,显著低于女性,P值分别为2.38±0.49和2.64±0.64,P值分别为0.012和0.023。男性血浆HDL-c和TGs的平均值分别为1.126±0.190 mmol/L和1.194±0.224 mmol/L,分别为0.77±0.20和0.82±0.27,P = 0.099和0.27,差异无统计学意义。24 ~ 27岁年龄组的平均值最高,28 ~ 40岁年龄组的平均值最低。然而,这些值在统计上没有差异。大多数参与者明显处于低正常参考范围内。结论:这些发现在大多数受试者的正常血脂范围内。
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