JRSM Cardiovascular Disease最新文献

{"title":"Association between high-sensitive cardiac troponin level and coronary artery disease: A systematic review and meta-analysis.","authors":"Alireza Fatemi, Mahdi Zahedi, Yasmin Yazdooei, Maryam Daei, Mohammad Mostafa Ansari, Ahmad Sohrabi, Arash Azizinejad, Mohammad Reza Hssanpour, Marzieh Behrouzifar, Hanieh Babapour","doi":"10.1177/20480040231220094","DOIUrl":"https://doi.org/10.1177/20480040231220094","url":null,"abstract":"<p><strong>Background and objectives: </strong>Previous studies suggest a link between high-sensitive cardiac troponin (hs-cTn) levels and coronary artery disease (CAD). However, the nature of this relationship is disputed. To address this, we conducted a study to gather and assess evidence on the association between hs-cTn and CAD prediction.</p><p><strong>Data sources: </strong>Studies were systematically searched and collected from four databases and different types of gray literature to cover all available evidence. After the screening, the selected articles' quality and risk of bias assessment were evaluated.</p><p><strong>Synthesis method: </strong>Meta-analysis calculated std. mean difference on the extracted data. Furthermore, heterogeneity, sensitivity, subgroups, and publication bias analyses were assessed.</p><p><strong>Results: </strong>Twenty-two studies were included in this systematic review, with a total of 844 cases and 2101 control people. The results of the meta-analysis on nine studies showed a significant and positive association between hs-cTn levels and CAD (pooled std. mean difference = 0.44; 95% confidence interval = 0.14-0.73; <i>p</i> < 0.003), with no publication bias (<i>p</i> = 0.9170). Among subgroups, std. mean differences were notably different only when the data were stratified by region or risk of bias; however, subgroup analysis could not determine the source of heterogeneity.</p><p><strong>Conclusions: </strong>Available prospective studies indicate a strong association of hs-cTn with the risk of CAD and significant improvements in CAD prediction. Further investigations in both molecular and clinical fields with proper methodology and more detailed information are needed to discover more evidence and underlying mechanisms to clear the interactive aspects of hs-cTn level in CAD patients.</p>","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"12 ","pages":"20480040231220094"},"PeriodicalIF":1.6,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10722913/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138810513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular risk factors among Cameroonian adolescents: Comparison between public and private schools and association with physical activity practice-a cross-sectional study.","authors":"Felicite Kamdem,&nbsp;Elysée Claude Bika Léle,&nbsp;Jerson Mekoulou Ndongo,&nbsp;Hamadou Ba,&nbsp;Marie Ange Prisca Obe Meyong,&nbsp;Jaff Fenkeu Kweban,&nbsp;Oumarou Moussa,&nbsp;Glwadys Ngono Atéba,&nbsp;Sidick Mouliom,&nbsp;Lade Viché,&nbsp;Henri Ngoté,&nbsp;Caroline Kenmegne,&nbsp;Marie Solange Ndom Ebongue,&nbsp;Siddikatou Djibrilla,&nbsp;Anastase Dzudié,&nbsp;Alain Ménanga","doi":"10.1177/20480040231210371","DOIUrl":"https://doi.org/10.1177/20480040231210371","url":null,"abstract":"<p><strong>Aim: </strong>Cardiovascular diseases are the leading cause of death worldwide and physical activity (PA) practice is recommended as the most efficient preventive measure to curse their burden in sub-Saharan Africa. Our study aimed to compare cardiovascular risk factors (CVRFs) in adolescents in public and private schools in Cameroon and assess the impact of PA practice.</p><p><strong>Methods: </strong>We conducted a cross-sectional study on students from private and public secondary schools in the city of Douala. Anthropometric parameters, blood glucose, and blood pressure (BP) were collected. PA was assessed using the short form of the International Physical Activity Questionnaire. Multivariate logistic regression was used to assess the influence of PA levels on different CVRFs. The differences were considered significant for <i>p</i> < .05.</p><p><strong>Results: </strong>We recruited 771 participants, aged 16 ± 1years, 51.4% female, and 48.6% private school students. Prevalence of CVRFs was 38.4%; 11.5%; 5.6%; 5.4%, and 3% for overweight/obesity, abdominal obesity, smoking, glucose homeostasis abnormalities, and high BP (HBP) respectively. Around 41% of participants had low PA level (LPA). Abdominal obesity and LPA were more common among girls (<i>p</i> < .0001 both) and 1.3% of participants had more than four CVRF. In multivariate analysis, LPA was significantly associated with a higher odd of HBP (<i>OR</i> = 7.69; <i>p</i> < .0001).</p><p><strong>Conclusion: </strong>The prevalence of various CVRF is high among Cameroonian adolescent schoolers. Public policies should focus on prevention programs through physical exercise and the reduction of smoking.</p>","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"12 ","pages":"20480040231210371"},"PeriodicalIF":1.6,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10612454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71414356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Cerebral venous sinus thrombosis following</i> ChAdOx1 nCoV-19 AstraZeneca COVID-19 vaccine.","authors":"Shyam S Sharma,&nbsp;Giosue Gulli,&nbsp;Pankaj Sharma","doi":"10.1177/20480040231169464","DOIUrl":"https://doi.org/10.1177/20480040231169464","url":null,"abstract":"<p><p>A woman in her mid-twenties was admitted with headache, ultimately leading to a diagnosis of cerebral venous sinus thrombosis 10 days after receiving a first dose of the AstraZeneca ChAdOx1 nCoV-19 vaccine (Vaxzevria). We report this case from clinical investigations to outcomes and discuss the issues raised by it regarding the ChAdOx1 nCoV-19 vaccine.</p>","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"12 ","pages":"20480040231169464"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10107960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9384313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of educational intervention in the prevention of cardiovascular diseases in patients with hypertension with application of health belief model: A quasi-experimental study","authors":"Fatemeh Mohammadkhah, Abbas Shamsalinia, Fatemeh Rajabi, Pooyan Afzali Hasirini, Ali Khani Jeihooni","doi":"10.1177/20480040231212278","DOIUrl":"https://doi.org/10.1177/20480040231212278","url":null,"abstract":"Background The best methods for preventing and controlling cardiovascular diseases are preventive behaviours. Aim The purpose of the current study is to ascertain how educational intervention affects cardiovascular disease prevention. Methods The current investigation is a quasi-experimental study conducted in Shiraz, Iran, in the year 2022, focusing on 200 hypertension patients (by sample random sampling) that were divided into two groups: a control group consisting of 100 participants (63 males and 37 females) and an intervention group also consisting of 100 participants (58 males and 42 females). The data collection instrument comprises inquiries pertaining to demographic factors as well as constructs of the health belief model (HBM) and preventive behaviours for cardiovascular diseases. The participants in both groups completed the questionnaire prior to and three months after the intervention. The intervention group underwent a total of six training sessions, each lasting 55 min. Results The results showed that after the intervention, the intervention group showed a significant increase in all cues of the HBM model except for the perceived barriers. Following a period of three months subsequent to the educational intervention, the experimental group also exhibited a notable reduction in blood pressure in comparison to the control group. Conclusion The findings of the study indicate that the utilisation of the HBM demonstrated positive outcomes in facilitating the promotion of cardiovascular disease prevention among patients diagnosed with hypertension. The promotion of health among individuals with high blood pressure can be both beneficial and feasible. Moreover, this particular model can be utilised as a comprehensive framework for the development, execution, and evaluation of advantageous and effective healthcare initiatives.","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"2016 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135507772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the use of blood pressure telemonitoring versus standard medical care in the achievement of short-term therapeutic goals in blood pressure in patients with uncontrolled hypertension: An open-label clinical trial.","authors":"M G Ramos-Zavala,&nbsp;F Grover-Páez,&nbsp;E G Cardona-Muñoz,&nbsp;D Cardona-Müller,&nbsp;A G Alanis-Sánchez,&nbsp;S Pascoe-González,&nbsp;D Roman-Rojas,&nbsp;C G Ramos-Becerra,&nbsp;H Alvarez-López,&nbsp;A Chávez-Mendoza,&nbsp;G J De la Peña-Topete,&nbsp;J M Enciso-Muñóz,&nbsp;A Estrada-Suárez,&nbsp;H Galvan-Oseguera,&nbsp;A Guerra-López,&nbsp;P Gutiérrez-Fajardo,&nbsp;K Lupercio-Mora,&nbsp;S N Nikos-Christo,&nbsp;S Palomo-Piñón,&nbsp;E Ruíz-Gastelum,&nbsp;R G Velasco-Sánchez","doi":"10.1177/20480040231178585","DOIUrl":"https://doi.org/10.1177/20480040231178585","url":null,"abstract":"<p><strong>Background: </strong>In Mexico less than half of the treated hypertensive patients reach blood pressure (BP) targets. Most hypertensive individuals rely on the standard medical care (SMC) to achieve the BP control goals; however, the efficacy of BP telemonitoring (BPT) to achieve BP targets has been poorly studied.</p><p><strong>Aim: </strong>To compare the efficacy of BPT versus SMC to achieve BP goals in patients with uncontrolled hypertension.</p><p><strong>Methods: </strong>A two-arm, open-label clinical trial was conducted in patients ≥18 years with uncontrolled hypertension. The participants were randomized to 2 arms (BPT vs SMC) and followed for 12 weeks. For the statistical analysis, the chi-squared test and covariance were used.</p><p><strong>Results: </strong>One hundred and seventy-eight participants were included, BPT (n = 94) and SMC (n = 84), after 12 weeks of follow up, we observed a baseline-adjusted reduction in systolic BP with both BPT (-13.5 [1.3] mmHg) and the SMC (-5.9 [1.4] mmHg; p < 0.001) but a greater decrease with BPT (p < 0.001). Likewise, we found a baseline-adjusted reduction of diastolic BP with BPT (-6.9 [0.9] mmHg) and SMC (-2.7 [0.9] mmHg) (p = 0.007) with a more significant percentage change from baseline with BPT (-6.8% [1.0] vs 2.5% [1.1]; p = 0.007). In the BPT arm, a larger proportion of patients achieved the BP target versus SMC (30.5% vs 12.8%; p = 0.005).</p><p><strong>Conclusion: </strong>BPT showed a greater proportion of patients achieving office BP control goals (<140/90 mmHg), compared to standard medical care.</p>","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"12 ","pages":"20480040231178585"},"PeriodicalIF":1.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e5/4e/10.1177_20480040231178585.PMC10280509.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9710729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Velocity encoded mitral valve inflow cine: A novel and more reproducible method to determine cardiac rest periods during coronary magnetic resonance angiography","authors":"R. Markus, A. Tandon, Munes Fares, J. Dillenbeck, G. Greil, M. Batsis, Joshua S. Greer, A. Potersnak, Song Zhang, T. Hussain, S. Avula","doi":"10.1177/20480040221087556","DOIUrl":"https://doi.org/10.1177/20480040221087556","url":null,"abstract":"A high temporal resolution, 4-chamber (4CH) cine is the standard method for determining cardiac rest periods during whole heart coronary magnetic resonance angiography (CMRA). We evaluated the image quality and reproducibility between the 4CH cine method and a novel approach using a velocity encoded mitral valve inflow cine (MVI). The goal of this study was to compare the quality of CMRAs utilizing MVI versus 4CH methods. Sharpness and vessel length for the LCA and RCA using each method were determined using Soap Bubble and two blinded observers independently assessed coronary image quality. Offline analysis on a separate, retrospective cohort (n = 25) was used to compare MVI and 4CH reproducibility. In the prospectively evaluated cohort there was no difference in overall vessel sharpness (4CH vs MVI mean ± SD) (31.0 ± 5.5% vs 30.5 ± 5.7%, p = .63), LCA vessel sharpness (30.0 ± 5.4% vs 31.1 ± 8.2%, p = .44), LCA length (4.7 ± 1.4 cm vs 4.6 ± 1.6 cm, p = .66), RCA vessel sharpness (32.1 ± 6.9% vs 31.1 ± 7.7%, p = .55), RCA length (5.51 ± 2.6 cm vs 5.95 ± 2.4 cm, p = .38), or image quality rating (2.66 vs 2.62, p = .80) between methods. In the retrospective cohort, the MVI method had 5.4% lower inter-observer variability (95% CI 3.7,7.2%, p < .0001) and 3.9% lower intra-observer variability (95% CI 2.4,5.4%, p < .0001) than the 4CH method. MVI is a technically feasible and more reproducible method to determine cardiac rest periods compared to 4CH while preserving vessel sharpness, vessel length & image quality.","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46656710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary-pulmonary artery fistula with lung hypoplasia and a bicuspid aortic valve: A case report","authors":"B. George, Michael R Sood","doi":"10.1177/20480040221082905","DOIUrl":"https://doi.org/10.1177/20480040221082905","url":null,"abstract":"Background With an incidence of less than 1%, a Coronary Artery to Pulmonary Artery fistula (CAPF) is a rare coronary anomaly that causes heart failure. It causes a left to right cardiac shunt. While guidelines favor surgical correction in symptomatic patients, we present a challenging case with multiple cardio-thoracic pathologies. Case Presentation We present a 38-year-old obese male with persistent atrial fibrillation (AF). He presented to our hospital in decompensated heart failure and AF with rapid ventricular response. He was found to have a CAPF, a bicuspid aortic valve and left lung hypoplasia in the presence of severely reduced left ventricular systolic dysfunction. The patient subsequently underwent various cardiac testing demonstrating advanced anatomical and physiologic involvement of his CAPF, including suggested coronary steal. Despite some indications for percutaneous or surgical referral, we optimized his AF and congestive heart failure in lieu of formulating a treatment strategy for his CAPF and other abnormalities. Conclusion This report illustrates a case of a young adult who presented in decompensated heart failure with newly diagnosed left ventricular systolic function and rapid AF, who had a triad of congenital defects including a CAPF, a bicuspid aortic valve and left lung hypoplasia. To the best of our knowledge, this triad of defects is unreported. This case highlights the clinical approach in the evaluation of a cardiac shunt and it's management strategies in the presence of multiple cardio-thoracic comorbidities.","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"11 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42018703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monitoring haemodynamic changes in rodent models to better inform safety pharmacology: Novel insights from <b><i>in vivo</i> studies and waveform analysis</b>.","authors":"Marieke Van Daele,&nbsp;Samantha L Cooper,&nbsp;Patrizia Pannucci,&nbsp;Edward S Wragg,&nbsp;Julie March,&nbsp;Iwan de Jong,&nbsp;Jeanette Woolard","doi":"10.1177/20480040221092893","DOIUrl":"https://doi.org/10.1177/20480040221092893","url":null,"abstract":"<p><p>Animal models are essential for assessing cardiovascular responses to novel therapeutics. Cardiovascular safety liabilities represent a leading cause of drug attrition and better preclinical measurements are essential to predict drug-related toxicities. Presently, radiotelemetric approaches recording blood pressure are routinely used in preclinical <i>in vivo</i> haemodynamic assessments, providing valuable information on therapy-associated cardiovascular effects. Nonetheless, this technique is chiefly limited to the monitoring of blood pressure and heart rate alone. Alongside these measurements, Doppler flowmetry can provide additional information on the vasculature by simultaneously measuring changes in blood flow in multiple different regional vascular beds. However, due to the time-consuming and expensive nature of this approach, it is not widely used in the industry. Currently, analysis of waveform data obtained from telemetry and Doppler flowmetry typically examines averages or peak values of waveforms. Subtle changes in the morphology and variability of physiological waveforms have previously been shown to be early markers of toxicity and pathology. Therefore, a detailed analysis of pressure and flowmetry waveforms could enhance the understanding of toxicological mechanisms and the ability to translate these preclinical observations to clinical outcomes. In this review, we give an overview of the different approaches to monitor the effects of drugs on cardiovascular parameters (particularly regional blood flow, heart rate and blood pressure) and suggest that further development of waveform analysis could enhance our understanding of safety pharmacology, providing valuable information without increasing the number of <i>in vivo</i> studies needed.</p>","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"11 ","pages":"20480040221092893"},"PeriodicalIF":1.6,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5f/b1/10.1177_20480040221092893.PMC9133998.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10600686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measurement of the cardiac time intervals of the fetal ECG utilising a computerised algorithm: A retrospective observational study.","authors":"S C Chivers,&nbsp;T Vasavan,&nbsp;M Nandi,&nbsp;B R Hayes-Gill,&nbsp;I A Jayawardane,&nbsp;J M Simpson,&nbsp;C Williamson,&nbsp;W P Fifer,&nbsp;M Lucchini","doi":"10.1177/20480040221096209","DOIUrl":"https://doi.org/10.1177/20480040221096209","url":null,"abstract":"<p><strong>Objective: </strong>Establish whether the reliable measurement of cardiac time intervals of the fetal ECG can be automated and to address whether this approach could be used to investigate large datasets.</p><p><strong>Design: </strong>Retrospective observational study.</p><p><strong>Setting: </strong>Teaching hospitals in London UK, Nottingham UK and New York USA.</p><p><strong>Participants: </strong>Singleton pregnancies with no known fetal abnormality.</p><p><strong>Methods: </strong>Archived fetal ECG's performed using the MonicaAN24 monitor. A single ECG (PQRST) complex was generated from 5000 signal-averaged beats and electrical cardiac time intervals measured in an automated way and manually.</p><p><strong>Main outcome measure: </strong>Validation of a newly developed algorithm to measure the cardiac time intervals of the fetal ECG.</p><p><strong>Results: </strong>188/236 (79.7%) subjects with fECGs of suitable signal:noise ratio were included for analysis comparing manual with automated measurement. PR interval was measured in 173/188 (92%), QRS complex in 170/188 (90%) and QT interval in 123/188 (65.4%). PR interval was 107.6 (12.07) ms [mean(SD)] manual vs 109.11 (14.7) ms algorithm. QRS duration was 54.72(6.35) ms manual vs 58.34(5.73) ms algorithm. QT-interval was 268.93 (21.59) ms manual vs 261.63 (36.16) ms algorithm. QTc was 407.5(32.71) ms manual vs 396.4 (54.78) ms algorithm. The QRS-duration increased with gestational age in both manual and algorithm measurements.</p><p><strong>Conclusion: </strong>Accurate measurement of fetal ECG cardiac time intervals can be automated with potential application to interpretation of larger datasets.</p>","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"11 ","pages":"20480040221096209"},"PeriodicalIF":1.6,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/51/3e/10.1177_20480040221096209.PMC9102181.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10253873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The burden of malnutrition & frailty in patients with coronary artery disease: An under-recognized problem","authors":"Samiullah Arshad, Samina S. Khan, Adham Karim, Vedant A. Gupta","doi":"10.1177/20480040221102741","DOIUrl":"https://doi.org/10.1177/20480040221102741","url":null,"abstract":"Elderly patients with coronary artery disease have a high prevalence of frailty and malnutrition. Frailty syndrome is associated with poor outcomes in patients with myocardial infarction. There is a known overlap between frailty and malnutrition, yet these are two different entities. Fried Frailty Phenotype, Frail Scale, timed up and go test, and gait speed are rapid screening tests that may identify patients with frailty in everyday clinical setting. Short Form MNA is a sensitive tool to screen for malnutrition. Despite the availability of several tools for screening for both these conditions, the screening rates remain low. We aim to create awareness about the impacts of frailty and malnutrition, provide a brief overview of tools available and highlight the importance of screening in this high-risk population.","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44363422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}