Revista Experiencia en Medicina del Hospital Regional Lambayeque最新文献

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Accesibilidad a medicamentos usados para el tratamiento de enfermedades crónicas no transmisibles durante la pandemia por COVID-19, Chiclayo- Perú, 2021 在 COVID-19 大流行期间慢性非传染性疾病治疗药物的可及性,奇克拉约-秘鲁,2021 年
Revista Experiencia en Medicina del Hospital Regional Lambayeque Pub Date : 2024-07-13 DOI: 10.37065/rem.v10i2.760
Maritza Mirella Gómez-Pita, Fabrizzio Elky Morales-Zaldívar, H. Arbildo-Vega
{"title":"Accesibilidad a medicamentos usados para el tratamiento de enfermedades crónicas no transmisibles durante la pandemia por COVID-19, Chiclayo- Perú, 2021","authors":"Maritza Mirella Gómez-Pita, Fabrizzio Elky Morales-Zaldívar, H. Arbildo-Vega","doi":"10.37065/rem.v10i2.760","DOIUrl":"https://doi.org/10.37065/rem.v10i2.760","url":null,"abstract":"Objective: To describe the accessibility of medicines used to treat chronic non-communicable diseases during the COVID-19 pandemic in Chiclayo city. Materials and Methods: The present study was observational, descriptive, cross-sectional and prospective, with a sample of 386 participants, conducted with a questionnaire validated by expert judgment and established reliability through a pilot test. It was structured in two sections, covering sociodemographic, economic and health characteristics of patients with chronic diseases during the COVID-19 pandemic and the four dimensions of accessibility (physical availability, affordability, geographic accessibility and acceptability). Results: 92.5% didn’t had full accessibility to medicines. 45.9%, 53.4%, 83.9% and 23.3% had physical availability, affordability, geographic accessibility and acceptability of medicines, respectively. When accessibility was related to associated factors, it was found that there was a statistically significant relationship (p<0.05) with age, number of people living in thehousehold, monthly income, number of medications and evolution of the disease. Conclusion: The majority of patients treated in health centers and hospitals in Chiclayo did not have full accessibility to their medications during the COVID-19 pandemic, and this was related to the number of people, monthly income, evolution of the disease, age and number of medications.","PeriodicalId":302638,"journal":{"name":"Revista Experiencia en Medicina del Hospital Regional Lambayeque","volume":"64 25","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141651659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Humanización y conocimiento: la caricia más hermosa del cuidado enfermero a pacientes viviendo con VIH 人性化与知识:对艾滋病患者护理最美的爱抚
Revista Experiencia en Medicina del Hospital Regional Lambayeque Pub Date : 2024-07-13 DOI: 10.37065/rem.v10i2.764
Ursula Elisa Elias-Bravo
{"title":"Humanización y conocimiento: la caricia más hermosa del cuidado enfermero a pacientes viviendo con VIH","authors":"Ursula Elisa Elias-Bravo","doi":"10.37065/rem.v10i2.764","DOIUrl":"https://doi.org/10.37065/rem.v10i2.764","url":null,"abstract":"The objective of this opinion article is to raise awareness about humanized care and the importance of knowledge about the diagnosis in order to provide comprehensive care and treatment to patients living with HIV/AIDS. Nowadays, the lack of human connection is a challenge for the nursing professional, so the humanized care provided to patients living with HIV (PLWHA) should not only be practiced in the Sexually Transmitted Infections Strategy ( STI) - HIV/AIDS and Hepatitis B, but in all the services of a hospital where a patient with this reality is treated, a problem that is evident every day when visiting patients living with HIV, admitted to the services. of hospitalization or who go to the hospital to be treated on an outpatient basis, where the nursing professionals who work in these areas often do not demonstrate empathy with the patient, feeling even in this century, stigma and discrimination in their care, and everything is given by a backbone fact: ignorance. Therefore, it is concluded that undergraduate training in the professional nursing career should begin, not only strengthening knowledge about the prevention of sexually transmitted infections, but also the importance of providing comprehensive care to patients. patients living with HIV/AIDS, breaking prejudice, since the holistic and humanistic vision of care must be the foundation in the training of students, being the engine of change to mold the nursing professional by providing dignified, quality care, with knowledge, based on values, promoting a culture of respect for human rights with a gender focus, to eliminate the stigma and discrimination associated with the infection.","PeriodicalId":302638,"journal":{"name":"Revista Experiencia en Medicina del Hospital Regional Lambayeque","volume":"26 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141651014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Características de la contractura muscular cervical de pacientes atendidos en un centro de salud de Chiclayo, Perú 秘鲁奇克拉约一家医疗中心收治的颈肌挛缩症患者的特征。
Revista Experiencia en Medicina del Hospital Regional Lambayeque Pub Date : 2024-06-13 DOI: 10.37065/rem.v10i2.752
Ingrid Jennifer Ochoa-Prada, Betty Lamadrid-Torres
{"title":"Características de la contractura muscular cervical de pacientes atendidos en un centro de salud de Chiclayo, Perú","authors":"Ingrid Jennifer Ochoa-Prada, Betty Lamadrid-Torres","doi":"10.37065/rem.v10i2.752","DOIUrl":"https://doi.org/10.37065/rem.v10i2.752","url":null,"abstract":"Objective. To determine the Sociodemographic and therapeutic characteristics of patients with cervical muscle contracture treated at the Reque Health Center, Chiclayo, 2022. Material and methods. Descriptive and prospective observational study in a population of 98 patients attended. The Sociodemographic data was collected through an interview, the therapeutic data through a collection sheet and the level of pain through the EVA scale. Results. The population was characterized by a mean age of 46.1 years, predominance of females (60.2%), and occupation as housewife (28.6%) and worker/farmer (23.5%). Likewise, 33.7% presented comorbidities, being arterial hypertension (48.5%) and type 2 diabetes mellitus (30.3%), the most frequent. Manual and kinesic techniques (75.0%), twice a week (59.2%) and one month (67.3%); they were the most frequent types, frequency and time of therapy; respectively. The level of very strong pain was the most frequent (66.3%), and was associated with the longest therapy time (p<0.001). Conclusions. Cervical muscle contracture in the study population occurred mainly between 30 and 59 years of age, females, and housewives. Likewise, the manual and kinesic techniques, with a frequency of twice a week for a month; were the most frequent therapeutic characteristics.","PeriodicalId":302638,"journal":{"name":"Revista Experiencia en Medicina del Hospital Regional Lambayeque","volume":"25 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141348528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hipoglicemia neonatal en recién nacidos a término en un hospital del norte de Perú, 2023 秘鲁北部一家医院足月新生儿的新生儿低血糖症,2023 年
Revista Experiencia en Medicina del Hospital Regional Lambayeque Pub Date : 2024-06-13 DOI: 10.37065/rem.v10i2.746
Sheyla Valencia-Roca, L. Becerra-Gutiérrez
{"title":"Hipoglicemia neonatal en recién nacidos a término en un hospital del norte de Perú, 2023","authors":"Sheyla Valencia-Roca, L. Becerra-Gutiérrez","doi":"10.37065/rem.v10i2.746","DOIUrl":"https://doi.org/10.37065/rem.v10i2.746","url":null,"abstract":"Objective. To determine the frequency and characteristics of hypoglycemia in term newborns attended in a hospital in northern Peru from January to September 2023; Material and methods. Descriptive observational design, quantitative approach. The population consisted of 21 neonates. Results. It was found that the most frequent maternal characteristics were: advanced maternal age (43%), 52% of the mothers had gestational diabetes, the most frequent BMI was obesity (43%), 57% of the mothers had delayed breastfeeding and 57% did not have controlled prenatal checkups. Likewise, 71% had a dystocic delivery. The most frequent neonatal characteristics in the study population were81% male, 43% were large for their gestational age, 62% did not present intrauterine delay, 90% did not present neonatal asphyxia and 76% did not present neonatal sepsis. Of the total number of neonates (1151) admitted to the Hospital Regional Docente de Trujillo during January-September 2023, only 21 (2%) developed neonatal hypoglycemia. Conclusion. It is concluded that among the most frequent maternal characteristics were gestational diabetes, advanced age and poorly controlled pregnant women, and a little more than half had dystocic delivery; and among the most frequent neonatal characteristics were male neonates and large for gestational age newborns. In addition, alow frequency of neonatal hypoglycemia was found in newborns born at term in the regional teaching hospital of Trujillo attended from January to September 2023.","PeriodicalId":302638,"journal":{"name":"Revista Experiencia en Medicina del Hospital Regional Lambayeque","volume":"53 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141349059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conocimiento sobre coagulopatía y tromboprofilaxis asociada a COVID-19 en internos de medicina humana de Chiclayo, Perú 秘鲁奇克拉约人类医学实习生对 COVID-19 相关凝血病症和血栓预防的了解。
Revista Experiencia en Medicina del Hospital Regional Lambayeque Pub Date : 2024-06-13 DOI: 10.37065/rem.v10i2.759
Alondra Gianella Erazo-Asenjo, Ángel Stevens García-Callao, Herry Lloclla-Gonzáles
{"title":"Conocimiento sobre coagulopatía y tromboprofilaxis asociada a COVID-19 en internos de medicina humana de Chiclayo, Perú","authors":"Alondra Gianella Erazo-Asenjo, Ángel Stevens García-Callao, Herry Lloclla-Gonzáles","doi":"10.37065/rem.v10i2.759","DOIUrl":"https://doi.org/10.37065/rem.v10i2.759","url":null,"abstract":"Objective: To describe the knowledge about coagulopathy and thromboprophylaxis associated with COVID-19 in medical interns of Chiclayo, 2021. Materials and methods: Observational, descriptive cross-sectional study. Census Study. A data collection form and a questionnaire validated by experts were used that assesses knowledge about coagulopathy and thromboprophylaxis associated withCOVID-19. It was applied to inmates who met the inclusion criteria. Results: One hundred fifty-five medical interns were surveyed. It was evidenced that the most accurate question about coagulopathy associated with COVID-19 with 80.6% was the following: “SARS-CoV-2 protein that binds to the ACE2 receptor to produce the cytokine storm” also regarding the second section corresponding tothromboprophylaxis the premise ¨Enoxaparin has a high activity on the coagulation factor¨ had 80.6%. Finally, regarding the knowledge of existing technical documents regarding this complication, only 33.5% of inmates were aware of it. Conclusions: It was determined that the majority of medical interns know about this complication and its prophylactic management, however, it was identified that very few interns are aware of the existence of technical documents regarding this complication.","PeriodicalId":302638,"journal":{"name":"Revista Experiencia en Medicina del Hospital Regional Lambayeque","volume":"49 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141349438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Susceptibilidad antifúngica y producción de fosfolipasas en Candida albicans y no albicans ailadas en un hospital de Chiclayo, Perú 秘鲁奇克拉约一家医院中患溃疡的白色念珠菌和非白色念珠菌对抗真菌的敏感性和磷脂酶的产生。
Revista Experiencia en Medicina del Hospital Regional Lambayeque Pub Date : 2024-06-13 DOI: 10.37065/rem.v10i2.745
Nelson Fredy Berrios-Estela, Rosa Jhaqueline Chapoñan-Coronado, Gianina Llontop-Barandiaran, Roberto Ventura-Flores
{"title":"Susceptibilidad antifúngica y producción de fosfolipasas en Candida albicans y no albicans ailadas en un hospital de Chiclayo, Perú","authors":"Nelson Fredy Berrios-Estela, Rosa Jhaqueline Chapoñan-Coronado, Gianina Llontop-Barandiaran, Roberto Ventura-Flores","doi":"10.37065/rem.v10i2.745","DOIUrl":"https://doi.org/10.37065/rem.v10i2.745","url":null,"abstract":"Objective: Determine the antifungal susceptibility and phospholipase production in Candida albicans and non-albicans in clinical samples from a hospital in Chiclayo, Peru. Material and methods: 60 isolates were identified with morphophysiological tests, while phospholipase production was determined using the semiquantitative method on Sabouraud dextrose agar plates supplemented with egg yolk, and susceptibility was performed using the disk diffusion method with fluconazole and voriconazole. Results: 95,5% of C. albicans were sensitive to fluconazole and voriconazole, while C. tropical and C. parapsilosis showed 100% sensitivity to both azoles. 14 strains of C. albicans had the highest production of phospholipase with 23,3% while the lowest was C. tropical with 25%. Conclusions: there was a high sensitivity to fluconazole and voriconazole in the isolates of Candida species. While 100% of C. albicansshowed phospholipase production.","PeriodicalId":302638,"journal":{"name":"Revista Experiencia en Medicina del Hospital Regional Lambayeque","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141349523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factores asociados a la calidad de atención en el servicio de laboratorio clínico de un centro de salud de Jaén, Perú 秘鲁哈恩市一家医疗中心临床实验室服务质量的相关因素。
Revista Experiencia en Medicina del Hospital Regional Lambayeque Pub Date : 2024-06-13 DOI: 10.37065/rem.v10i2.757
Eva Yessenia Mendoza-Romero, Luis Alberto Valdiviezo-Cánova
{"title":"Factores asociados a la calidad de atención en el servicio de laboratorio clínico de un centro de salud de Jaén, Perú","authors":"Eva Yessenia Mendoza-Romero, Luis Alberto Valdiviezo-Cánova","doi":"10.37065/rem.v10i2.757","DOIUrl":"https://doi.org/10.37065/rem.v10i2.757","url":null,"abstract":"Objective. Determine the perceived quality of care and sociodemographic characteristics of users of the clinical laboratory service of the Centro de Salud Pucará, Jaén, Peru, 2023. Material and methods. Non-experimental and correlational study in a representative and probabilistic sample of 197 external users. The quality of care was measured with a SERVQUAL scale validated for the clinical laboratory service; while the sociodemographic variables and provision through a structured interview guide. Results. The sample was characterized by a median age of 37 years, predominance of the female sex (60.4%), married marital status (54.8%), level of secondary education (53.8%), Castilian ethnicity (69.0%) and type of continuing user (73.6%). 37.6% (95%CI=30.8 - 44.4) and 28.4% (22.1 - 34.7) perceived good and poor quality of care, respectively. An association was observed between the type of user and poor quality of care (p=0.012), where the new user was twice as likely to perceive poor quality of care compared to the continuing user (p=0.001; RPa=2, 01; 95%CI=1.33 - 3.05). Conclusions. Two to three out of every 10 external users in the study population expressed poor quality of care, which was related to the type of new user.","PeriodicalId":302638,"journal":{"name":"Revista Experiencia en Medicina del Hospital Regional Lambayeque","volume":"37 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141350179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factores asociados a la recaída de tuberculosis pulmonar en internos de un centro penitenciario de Chiclayo, Perú 秘鲁奇克拉约一所监狱囚犯肺结核复发的相关因素。
Revista Experiencia en Medicina del Hospital Regional Lambayeque Pub Date : 2024-04-10 DOI: 10.37065/rem.v10i1.743
César Arturo Ñañez-Vasquez, Arthur Edward Castro-Puelles, Herry Lloclla-Gonzales
{"title":"Factores asociados a la recaída de tuberculosis pulmonar en internos de un centro penitenciario de Chiclayo, Perú","authors":"César Arturo Ñañez-Vasquez, Arthur Edward Castro-Puelles, Herry Lloclla-Gonzales","doi":"10.37065/rem.v10i1.743","DOIUrl":"https://doi.org/10.37065/rem.v10i1.743","url":null,"abstract":"Objetivo. Determinar la asociación de las características sociodemográficas y clínicas con la recaída de tuberculosis pulmonar en internos de un centro penitenciario del norte del Perú, 2016-2020. Métodos. Estudio observacional, de tipo transversal analítico en 898 internos con tuberculosis confirmada. Los datos se recolectaron mediante la documentación de las historias clínicas. Resultados. La población se caracterizó por una mediana de edad de 27,5 años y predominio de sexo masculino (98,7 %), estado de desnutrición (95,7 %), abuso de drogas (96,5 %) y tabaquismo (100,0 %). La frecuencia de recaída de tuberculosis fue 26,4%. La edad entre 30 a 59 años (p= 0,025; RP=1,45; IC95%: 1,15-1,82) y la localización pulmonar de la tuberculosis (p=0,001; RP=2,59; IC95%: 1,50-4,47) estuvieron asociadas la mayor probabilidad de presentar recaídas. Conclusión. Las recaídas de tuberculosis en internos penitenciarios es un problema vigente y está relacionada al sexo masculino, edad adulta, la localización pulmonar y el abuso de drogas y tabaquismo.  ","PeriodicalId":302638,"journal":{"name":"Revista Experiencia en Medicina del Hospital Regional Lambayeque","volume":"2001 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140718736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Guía de procedimiento asistencial de enfermería en el cuidado a pacientes con lesiones de pie diabético de grado I I 级糖尿病足病变患者护理程序指南
Revista Experiencia en Medicina del Hospital Regional Lambayeque Pub Date : 2024-04-08 DOI: 10.37065/rem.v10i1.749
Patricia del Rosario Purizaca-Bazán, Leyla Rossana Gonzáles-Delgado
{"title":"Guía de procedimiento asistencial de enfermería en el cuidado a pacientes con lesiones de pie diabético de grado I","authors":"Patricia del Rosario Purizaca-Bazán, Leyla Rossana Gonzáles-Delgado","doi":"10.37065/rem.v10i1.749","DOIUrl":"https://doi.org/10.37065/rem.v10i1.749","url":null,"abstract":"El déficit de criterios unificados en la practica  de los cuidados de enfermería, puede conllevar a incurrir errores durante los procedimientos. Por esta razón, la presente guía de procedimiento asistencial de enfermería (GPAE) tiene como objetivo, estandarizar los cuidados de enfermería sobre el tratamiento de lesiones de pie diabético de grado I y disminuir las complicaciones como la amputación. Tipo de estudio  descriptivo, de revisión de literatura; el proceso de recolección de la información se realizó mediante una búsqueda exhaustiva en revistas de alto impacto y otros medios confiables como Scopus, ProQuest, EBSCO, Scielo, repositorios y Google Académico. Esta revisión aborda las indicaciones, contraindicaciones, materiales y equipos necesarios, etapas del procedimiento de atención, las complicaciones y recomendaciones. Se concluye que la GPAE, permite minimizar errores y normalizar los cuidados enfermeros a pacientes con lesiones de pie diabetico de grado I, generando impacto en la salud de la población. Finalmente se enfatiza seguir desarrollando GPAE  para generar expectativas en los cuidados enfermeros y en la salud del país.","PeriodicalId":302638,"journal":{"name":"Revista Experiencia en Medicina del Hospital Regional Lambayeque","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140732280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibioticoterapia empírica asociada a mortalidad en pacientes con sepsis por SARS-CoV-2 经验性抗生素治疗与 SARS-CoV-2 败血症患者的死亡率有关
Revista Experiencia en Medicina del Hospital Regional Lambayeque Pub Date : 2024-04-05 DOI: 10.37065/rem.v10i1.739
Luis Angel Coaguila-Cusicanqui, J. I. J. Mejia-Parra, Jorge Guillermo Morales-Ramos, Ariana Lizeth Montenegro-Sialer, Yuriko Lizbeth Cavero-Reyes, F. Aguilar-Gamboa, M. M. Coico-Vega
{"title":"Antibioticoterapia empírica asociada a mortalidad en pacientes con sepsis por SARS-CoV-2","authors":"Luis Angel Coaguila-Cusicanqui, J. I. J. Mejia-Parra, Jorge Guillermo Morales-Ramos, Ariana Lizeth Montenegro-Sialer, Yuriko Lizbeth Cavero-Reyes, F. Aguilar-Gamboa, M. M. Coico-Vega","doi":"10.37065/rem.v10i1.739","DOIUrl":"https://doi.org/10.37065/rem.v10i1.739","url":null,"abstract":"Introducción: La sepsis por SARS-CoV-2 ha incrementado el uso de la antibioticoterapia empírica con el fin de reducir la mortalidad, aunque no existe suficiente evidencia de esto. Objetivo: Determinar si el uso de antibioticoterapia empírica se asocia con mortalidad a los 28 días en pacientes con sepsis por SARS-CoV-2 en el Servicio de Emergencias y Áreas Críticas del Hospital Regional de Lambayeque, Perú. Material y Métodos: El estudio de cohorte prospectivo de 102 pacientes con diagnóstico de sepsis por SARS-CoV-2, donde 52 recibieron antibioticoterapia empírica y 50 no recibieron antibioticoterapia empírica, de febrero a septiembre del 2021. Resultados: Se encontraron diferencias significativas con valores elevados de procalcitonina (p=0,03) y leucocitos (p=0,025), valores bajos de albúmina (p =0,01), y puntuaciones elevadas en la escala SOFA (p=0,022) en pacientes que recibieron antibioticoterapia empírica. El análisis de supervivencia de Kaplan Meier determinó que la antibioticoterapia empírica por sí sola no es una variable significativa para la mortalidad (p=0,89); sin embargo, el análisis de regresión multivariable de COX obtuvo que el uso de antibioticoterapia empírica (HR 1,9 IC 95% 1,02-3,91), PafiO2 (0,99 IC 95% 0,98-1,00), días libres de ventilación mecánica (HR 0,89 IC 95% 0,84-0,94) y la edad (HR 1,03 IC 95% 1,003-1,051) son predictores de mortalidad. Conclusiones: Los resultados de este estudio muestran discrepancias y no permiten concluir de manera definitiva si existen diferencias estadísticamente significativas en la mortalidad entre el grupo que recibió antibioticoterapia y el grupo que no la recibió. Se requieren investigaciones adicionales para obtener conclusiones más sólidas en relación con este aspecto. Sin embargo, las coinfecciones bacterianas fueron poco frecuentes, en pacientes que recibieron antibióticos. Además, la asociación encontrada entre el uso de antimicrobianos y la disminución de los niveles de albúmina, incremento de leucocitos y puntuaciones SOFA requieren un mayor estudio para comprender mejor sus implicaciones clínicas.","PeriodicalId":302638,"journal":{"name":"Revista Experiencia en Medicina del Hospital Regional Lambayeque","volume":"21 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140739139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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