K. Leung, R. Baldewsing, F. Mastik, J. Schaar, A. Gisolf, A. V. D. van der Steen
{"title":"Motion compensation for intravascular ultrasound palpography for in vivo vulnerable plaque detection","authors":"K. Leung, R. Baldewsing, F. Mastik, J. Schaar, A. Gisolf, A. V. D. van der Steen","doi":"10.1109/ULTSYM.2005.1602843","DOIUrl":"https://doi.org/10.1109/ULTSYM.2005.1602843","url":null,"abstract":"Intravascular ultrasound (IVUS) palpography assesses the mechanical properties of coronary arteries in vivo by radial strain measurements. This is accomplished by cross- correlating RF signals acquired at different systemic pressures. However, catheter motion due to cardiac activity causes misalignment of these signals, so that less strain estimates are obtained. Four motion compensation methods have been studied for correcting in-plane catheter rotation and translation. The best method, local block matching, achieved an increase of 15% in the number of strain estimates. Application of motion compensation methods improves IVUS palpography, resulting in better vulnerable plaque detection.","PeriodicalId":302030,"journal":{"name":"IEEE Ultrasonics Symposium, 2005.","volume":"354 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125637901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A novel back scattering ultrasound transducer for non-destructive material evaluation and defect inspection","authors":"C. Chung, Y. Lee, S. Kuo, Chu-Lin Chiu","doi":"10.1109/ULTSYM.2005.1602824","DOIUrl":"https://doi.org/10.1109/ULTSYM.2005.1602824","url":null,"abstract":"This research proposes a new type of focusing ultrasound transducer called Analytical Back Scattering Arrayed Ultrasound Transducer (ABSAUT). Different to the conventional focusing ultrasound transducer, an additional PVDF film with patterned electrodes is attached to the concave spherical surface for collecting back scattered ultrasound. It is designed for detecting and characterizing internal defects of a sample in an analytic and quantitative way via multiple back scattering ultrasound signals collection. Standard testing including pulse echo, transducer defocusing testing and sound field scanning are carried out and all the information is recorded for performance verification. Furthermore, a powerful angular spectrum algorithm is involved in the study for time-domain waveform prediction measured by the PVDF sensing elements. In this work, we have proved that ABSAUT can collect the reflected or back scattering sound wave information from the sample under testing. And the time-domain waveform predicted by angular spectrum algorithm also shows good agreement with the data measured by PVDF sensing elements. Finally, future improvements and applications of the ABSAUT will be addressed.","PeriodicalId":302030,"journal":{"name":"IEEE Ultrasonics Symposium, 2005.","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122770838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. van Neer, F. N. van de Vosse, N. de Jong, A. V. D. van der Steen, E. Vlaanderen, A. Bouakaz, J. de Hart
{"title":"In-vitro development of a novel method to noninvasively establish BScc valve integrity","authors":"P. van Neer, F. N. van de Vosse, N. de Jong, A. V. D. van der Steen, E. Vlaanderen, A. Bouakaz, J. de Hart","doi":"10.1109/ULTSYM.2005.1603044","DOIUrl":"https://doi.org/10.1109/ULTSYM.2005.1603044","url":null,"abstract":"Purpose: the Bjork-Shiley convexo concave (BScc) mechanical heart valve has an increased occurrence of unexpected mechanical failure of the outlet strut of the valve compared to equivalent valve types, with a high incidence of mortality, when it occurs. Until now no noninvasive method to determine BScc valve integrity with adequate performance has been developed. The purpose of this study is the development of a novel method to establish BScc valve integrity in-vitro. Method: the proposed method analyses the movement of both legs of the BScc valves outlet strut during the cardiac cycle. It is based on the assumption that a broken leg will have increased movement compared to either the intact leg or the flange. BScc heart valves were mounted in the mitral position in an in-vitro pulse duplicator system, which is a plexiglass model of the left ventricle that can mimic the hydrodynamics in the ventricle and concomitant forces of heart valves. A focused single element ultrasound transducer (10 MHz) is excited using a sinusoidal wave to direct ultrasound, on a particular leg of the outlet strut. Correlation based time delay estimation is then used to estimate the difference in time of flight of the echoes during the cardiac cycle. These differences are subsequently converted to produce the movement of the outlet strut during the cardiac cycle. Results: the movement of two valves has been studied, one intact valve and a valve with a single leg fracture with both ends grating against each other (SLF). No significant difference in movement could be detected between both legs of the intact BScc valve (amplitude of movement 9.2 µm ± 0.1 µm). However, the amplitude of movement of the broken leg of the SLF valves outlet strut was 12 µm ± 1.6 µm versus 8.6 µm ± 0.1 µm for the intact leg. Conclusions: the detection of a difference in movement between the broken and the intact leg (or flange) is the most difficult in the case of an SLF BScc valve, as broken leg movement is damped the most in this case. Therefore, a larger difference in movement between both legs of the outlet strut (or the broken leg and the flange) is expected for valves with a nongrating type of fracture. The proposed method has shown to be feasible in vitro and has potential for the in vivo detection of BScc valve outlet strut fracture.","PeriodicalId":302030,"journal":{"name":"IEEE Ultrasonics Symposium, 2005.","volume":"110 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128992581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. van Stralen, M. Voormolen, G. van Burken, B. Krenning, R. V. van Geuns, E. Angelié, R. J. van der Geest, C. Lancée, N. de Jong, A. V. D. van der Steen, J. Reiber, J. Bosch
{"title":"A novel dynamic programming based semi-automatic endocardial border detection method for 4D cardiac ultrasound","authors":"M. van Stralen, M. Voormolen, G. van Burken, B. Krenning, R. V. van Geuns, E. Angelié, R. J. van der Geest, C. Lancée, N. de Jong, A. V. D. van der Steen, J. Reiber, J. Bosch","doi":"10.1109/ULTSYM.2005.1603072","DOIUrl":"https://doi.org/10.1109/ULTSYM.2005.1603072","url":null,"abstract":"We propose a semi-automatic endocardial border detection method for left ventricular volume estimation in 3D time series of cardiac ultrasound data. We evaluated on data acquired with the Fast Rotating Ultrasound (FRU) transducer: a linear phased array transducer rotated at high speed around its image axis, generating high quality 2D images of the heart. From four manually drawn contours a 3D + time shape and edge pattern model is derived from which contour shape and edge patterns are estimated for each image using the models. Pattern matching and dynamic programming is applied to detect the contours automatically. The method allows easy corrections in the detected 2D contours, to iteratively achieve more accurate models and improved detections. An evaluation of this method on FRU data against MRI was done for full cycle LV volumes on 10 patients. Good correlations were found against MRI volumes (r=0.94, y=0.73x + 30.3, difference of 9.6 +/- 17.4 ml (Av +/- SD)) and a low interobserver variability for US (r=0.94, y=1.11x - 16.8, difference of 1.4 +/- 14.2 ml). On average only 2.8 corrections per patient were needed (in a total of 160 images). Although the method shows good correlations with MRI without corrections, applying these corrections can make considerable improvements. Keywords-component; 3-dimensional ultrasound; left ventricle;","PeriodicalId":302030,"journal":{"name":"IEEE Ultrasonics Symposium, 2005.","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126924552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Yoshinori, T. Yanagitani, M. Matsukawa, Y. Watanabe
{"title":"Higher-order shear mode FBAR using polarization-inverted layers of (1120) textured zno films","authors":"M. Yoshinori, T. Yanagitani, M. Matsukawa, Y. Watanabe","doi":"10.1109/ULTSYM.2005.1603224","DOIUrl":"https://doi.org/10.1109/ULTSYM.2005.1603224","url":null,"abstract":"Second-order shear mode FBAR using (1120) textured ZnO film was fabricated. This FBAR contained two ZnO layers with opposite polarizations. Crystallites growth directions of the ZnO layers were clarified by X-ray pole figure analysis. Characteristics of this FBAR were experimentally and theoretically investigated. Keywords-component; Shear mode; Higher order mode FBAR; (1120) textured Zinc Oxide; Polarization-inverted piezoelectric layers","PeriodicalId":302030,"journal":{"name":"IEEE Ultrasonics Symposium, 2005.","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128805439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High precision tuning fork sensor for liquid property measurements","authors":"L. Matsiev, J. Bennett, O. Kolosov","doi":"10.1109/ULTSYM.2005.1603140","DOIUrl":"https://doi.org/10.1109/ULTSYM.2005.1603140","url":null,"abstract":"Application of piezoelectric flexural mechanical resonators such as tuning forks to accurate measurements of liquid physical properties is discussed. It was shown earlier that liquid properties such as viscosity, density and dielectric constant can be obtained by measuring the resonator AC impedance within certain frequency range and fitting it to the resonator equivalent circuit model (1). Error sources for the liquid property measurements and their influence on the measured value are investigated. It is shown experimentally that the reproducibility of the viscosity and density measurements using this technique can meet and often exceed the one delivered by the well established analytical instrumentation. It is also demonstrated here that better performance is resulting from the use of the whole impedance curve over a frequency range, which produces better statistics and natural averaging of the noise.","PeriodicalId":302030,"journal":{"name":"IEEE Ultrasonics Symposium, 2005.","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123743745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Chin, A. van Wamel, M. Emmer, N. de Jong, C. Hall, A. Klibanov
{"title":"Mechanisms of ultrasonically-mediated drug delivery: high-speed camera observations of microbubbles with attached microbeads","authors":"C. Chin, A. van Wamel, M. Emmer, N. de Jong, C. Hall, A. Klibanov","doi":"10.1109/ULTSYM.2005.1602779","DOIUrl":"https://doi.org/10.1109/ULTSYM.2005.1602779","url":null,"abstract":"Ultrasonically-triggered drug delivery may be ac- complished through the attachment of drug-enriched liposomes to microbubble contrast agent. Understanding of the dynamics and mechanisms of drug release is needed to ensure robust and reproducible delivery of pharmaceutical payloads. Fluorescent microbeads were attached to stabilized perfluorobutane mi- crobubbles with avidin-biotin bonding. The resulting bubble-bead complex is a model for a drug-loaded ultrasound contrast agent. In a preliminary experiment using fluorescent microscopy, the destruction of microbubbles and release of beads were observed during exposure to diagnostic ultrasound. Detailed observations were made using the Brandaris-128 camera operated at 13 million frames per second (Mfps) speed. The bead-bubble complexes were exposed to 2.0 MHz, 10-cycle ultrasonic pulses at up to 0.65 MPa peak negative amplitude. Release and displacement of fluorescent microbeads from their original position was observed during insonation. Detached beads track the fluid flow induced by the bubble compression and expansion, at velocities greater than 10 m/sec. The translational and oscillatory movement of detached beads diminishes as the distance between the bubble and the bead increases. The results did not establish the capability of ultrasound to propel microbeads to a distance greater than a few cell layers. In short, this study exposed the process of the ultrasound-mediated release and subsequent movement of shell- associated microbeads with high temporal resolution.","PeriodicalId":302030,"journal":{"name":"IEEE Ultrasonics Symposium, 2005.","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126892841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Rønnekleiv, J. Brungot, D. Wang, R. Bernstein, V. Jahr, K. Kjølerbakken, L. Hoff, S. Holm
{"title":"Design of micromachined resonators for fish identification","authors":"A. Rønnekleiv, J. Brungot, D. Wang, R. Bernstein, V. Jahr, K. Kjølerbakken, L. Hoff, S. Holm","doi":"10.1109/ULTSYM.2005.1602934","DOIUrl":"https://doi.org/10.1109/ULTSYM.2005.1602934","url":null,"abstract":"The ID tag presented here was designed to give a tag of small size that could be produced at a low prize, and that could be read remotely in live fish, even in seawater. The last condition precludes use of electromagnetic waves for interrogation of the tags, and acoustic interrogation is then a clear alternative. The solution presented is a passive tag with a set of acoustic resonances that may be detected acoustically. The tag operates in the 200 to 400 kHz range. The identity of the tag is given by a unique combination of resonances in this frequency range. For the tags presented here there are five resonances per tag. If five or more resonances are chosen from a predetermined set of say 17 resonance frequencies, a total number of at least 3000 to 4000 different tags are available. This is adequate for classification of fish at the batch level in fish farms, or of local wild fish tribes. The resonators on a tag consists of a thin, nominally 500 nm thick silicon nitride membrane suspended over separate evacuated cavities, made by bulk silicon micromachining. The resonators were designed to have Q-factors in the range 27 to 35 with viscous losses in the water neglected. The resonators have been measured in water and in dead or live anesthetized fish from distances up to 30 cm. Sharp resonances in fair accordance with the tag design were achieved. Some alterations of the tag response with change of the angular orientation of the tag relative to the ultrasound beam are seen. This is also theoretically expected.","PeriodicalId":302030,"journal":{"name":"IEEE Ultrasonics Symposium, 2005.","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124403431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Lafond, T. Jackson, G. Baum, X. Zhang, P. Ridgway, R. Russo
{"title":"Laser Ultrasonics at 20 m/s in the production environment and on a budget: from dream to reality","authors":"E. Lafond, T. Jackson, G. Baum, X. Zhang, P. Ridgway, R. Russo","doi":"10.1109/ULTSYM.2005.1603020","DOIUrl":"https://doi.org/10.1109/ULTSYM.2005.1603020","url":null,"abstract":"A laser-based ultrasonic system for non-contact and non-destructive measurement of the elastic properties of paper was demonstrated on a paper manufacturing machine during commercial operation with paper moving around 20 m/s. We believe this to be the highest sample traveling speed reported to date for a commercial application of laser ultrasonics. Ultrasonic waves were generated in the paper with a pulsed Nd:YAG laser at 1064 nm wavelength and detected with a Mach-Zehnder interferometer coupled with a scanning mirror/timing system to compensate for paper motion. Measurements of the flexural rigidity (FR) and out-of-plane shear rigidity (SR) of the paper web were done automatically by fitting the frequency dependence of the phase velocity of Ao mode Lamb waves to a model wave propagation equation. Variation in FR and SR across the width of the paper sheet (cross-direction profiles), effects of changes in paper manufacturing process variables on measured FR and SR, comparisons with traditional mechanical stiffness tests are presented. The sensor head is fully optical and thus measures the web properties without any contact. This laser-ultrasonics system combines a very reasonable cost with a relatively small footprint and low power consumption due to the low power output of the lasers that are used. Finally, laboratory data indicate that this technology is directly transferable to measurements on sheet metals and possibly other opaque web materials","PeriodicalId":302030,"journal":{"name":"IEEE Ultrasonics Symposium, 2005.","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125228358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}