Xinyu Li;Jingyuan Zhang;Zixuan Cai;Xiong Wei Wu;Qiaocong Peng;Qian Ma;Jian Wei You;Tie Jun Cui
{"title":"Dynamic Electromagnetic Model to Detect Human Vital Signs Based on Time-Domain Finite Integration Theorem","authors":"Xinyu Li;Jingyuan Zhang;Zixuan Cai;Xiong Wei Wu;Qiaocong Peng;Qian Ma;Jian Wei You;Tie Jun Cui","doi":"10.1109/JERM.2024.3507005","DOIUrl":"https://doi.org/10.1109/JERM.2024.3507005","url":null,"abstract":"Contactless human vital-sign sensing using electromagnetic (EM) waves has made significant progress over the past few years and been practically applicable to a variety of fields such as smart home and healthcare. However, the further development of this technology is hindered by factors such as large volumes of data, long observation periods, and data variability. To deal with this challenge, a dynamic human EM model composed of customized time-varying EM materials is proposed to simulate the periodic characteristics of human cardiopulmonary motions and obtain physiological signals caused by the movements. The EM problem is subsequently addressed by employing the Time-Domain Finite Integration Technique (TDFIT), so that the EM scattering properties associated with human cardiopulmonary movements can be accurately analyzed. To validate the effectiveness of the proposed human EM model, we process the simulated human physiological signals for respiration and heartbeat rate estimation, with the error less than 4% and 8%, respectively. Furthermore, measured experiments are conducted to collected actual human vital-sign signals for comparison. Good agreement between the measured and simulated results demonstrates that the proposed human EM model is capable of accurately simulating the periodic cardiopulmonary motions and thus providing simulated physiological measurements for preliminary validation of vital sign sensing algorithms.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":"9 2","pages":"240-250"},"PeriodicalIF":3.0,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144117265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"IEEE Journal of Electromagnetics, RF, and Microwaves in Medicine and Biology About this Journal","authors":"","doi":"10.1109/JERM.2024.3496595","DOIUrl":"https://doi.org/10.1109/JERM.2024.3496595","url":null,"abstract":"","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":"8 4","pages":"C3-C3"},"PeriodicalIF":3.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10765925","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142691809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology Publication Information","authors":"","doi":"10.1109/JERM.2024.3496599","DOIUrl":"https://doi.org/10.1109/JERM.2024.3496599","url":null,"abstract":"","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":"8 4","pages":"C2-C2"},"PeriodicalIF":3.0,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10765930","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142691816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Integrated Boundary-Overlap-Size Metric for Local Assessment of Deep Learning Methods in Medical Microwave Imaging","authors":"Fei Xue;Lei Guo;Alina Bialkowski;Amin M. Abbosh","doi":"10.1109/JERM.2024.3485250","DOIUrl":"https://doi.org/10.1109/JERM.2024.3485250","url":null,"abstract":"Deep learning has been a game-changer in enhancing the speed and accuracy of medical microwave imaging in detecting abnormal lesions. Nonetheless, the challenge lies in establishing a universal objective metric to assess the reliability of these methods. Current evaluation practices often rely on a single geometric metric, which presents inherent constraints. Consequently, the evaluations of results generated by deep learning methods may not always reflect clinicians’ insights and judgments. To overcome this, a local assessment metric incorporating the following three geometric dimensions is proposed: the overlap between the detected anomaly and the actual lesion, the proximity of their boundaries, and the proportionality of the lesion sizes determined by the algorithm versus the actual lesion. This approach to evaluation ensures that the resulting metric's score is in line with professional medical diagnostics. The presented results on head imaging using five deep learning algorithms confirm the significant advantages of the proposed metric, validating its effectiveness in providing objective evaluation of various algorithms in medical electromagnetic imaging. This objective metric is poised to guide future algorithm development to ensure a reliable assessment of their capability in abnormality detection and diagnosis.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":"9 2","pages":"229-239"},"PeriodicalIF":3.0,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144117170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahnaf Tahmid;Tanzim Rahman;S. M. Ali Emam;Syeda Maliha Reza;Md Ismail Hosen;Reefat Inum;Ahsan Habib
{"title":"Low-Cost and Easy-to-Fabricate Microwave Sensor for Sensitive Glucose Monitoring: A Step Towards Continuous Glucose Monitoring","authors":"Ahnaf Tahmid;Tanzim Rahman;S. M. Ali Emam;Syeda Maliha Reza;Md Ismail Hosen;Reefat Inum;Ahsan Habib","doi":"10.1109/JERM.2024.3477596","DOIUrl":"https://doi.org/10.1109/JERM.2024.3477596","url":null,"abstract":"Basal-bolus insulin therapy is associated with frequent injections, dosing errors, and hypoglycemia risks. Integrating continuous glucose monitoring (CGM) with insulin pumps offers several advantages. However, current CGM systems lack accuracy and have high costs. To overcome these challenges, a CGM system requires sensor with enhanced sensitivity and low cost. In this study, we develop a planar microwave resonator-based sensor for sensitive glucose detection in human serum and whole blood. We track the variation in the transmission coefficient (<inline-formula><tex-math>$s_{21}$</tex-math></inline-formula>) to deduce changes in glucose concentration. Utilizing combinations of complementary split ring resonators (CSRRs) and complementary electric-LC (CELC) structures, the sensor achieves remarkable sensitivity, notably 37.3 mdB/(mg/dL) for glucose in human serum and 1.557 mdB/(mg/dL) for glucose in whole blood. We also evaluate other performance metrics, linearity (<inline-formula><tex-math>$R^{2} = 0.985$</tex-math></inline-formula> for serum and <inline-formula><tex-math>$R^{2} = 0.963$</tex-math></inline-formula> for whole blood), and limit of detection (LOD) of 477.75 μg/dL for serum and 53.84 mg/dL for whole blood. While we initially use an FR-4 rigid substrate in our proof-of-concept demonstration, we also investigate the feasibility of employing a flexible polyimide substrate. Our flexible glucose sensor shows an order of magnitude better performance than our rigid sensor.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":"9 2","pages":"221-228"},"PeriodicalIF":3.0,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144117266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alejandra Garrido-Atienza;Marta Guardiola;Luz Maria Neira;Jordi Romeu;Andreas Fhager
{"title":"Movement Tracking and False Positive Reduction Method for Microwave Colonoscopy Systems","authors":"Alejandra Garrido-Atienza;Marta Guardiola;Luz Maria Neira;Jordi Romeu;Andreas Fhager","doi":"10.1109/JERM.2024.3476964","DOIUrl":"https://doi.org/10.1109/JERM.2024.3476964","url":null,"abstract":"This paper presents a novel computational method for addressing the challenge of uncontrolled antenna movement in microwave imaging systems for colonoscopy. The proposed method tracks the movement of the antenna array by analyzing phase shifts in S-parameters across multiple channels. By exploiting the symmetry of the probe and correlating phase changes with displacement, this technique reduces false positives due to probe movements artifacts in real-time. Simulated and experimental results in a colon phantom model show that this method can correct displacements of up to 6 mm, reducing the artifacts in reconstructed images notably.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":"9 2","pages":"214-220"},"PeriodicalIF":3.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144117269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Robert M. Jones;Randall W. Reynolds;Alison K. Thurston;Robyn A. Barbato
{"title":"Fungal Tissue as a Medium for Electrical Signal Transmission: A Baseline Assessment With Melanized Fungus Curvularia Lunata","authors":"Robert M. Jones;Randall W. Reynolds;Alison K. Thurston;Robyn A. Barbato","doi":"10.1109/JERM.2024.3476444","DOIUrl":"https://doi.org/10.1109/JERM.2024.3476444","url":null,"abstract":"Fungal tissues are an underexplored medium for data and electrical signal transmission. Fungal tissues are a biodegradable material that can be cultivated in mass quantities; potentially making them sustainable materials for biological sensors or as a communication medium. Because the interactions of fungal tissues with communications signals are not thoroughly explored, a baseline assessment of the signal transmission capabilities of mat forming filamentous fungus, <italic>Curvularia lunata</i> (<italic>C. lunata</i>) was performed. In this paper, the band-pass characteristics of <italic>C. lunata</i> were assessed through a frequency sweep from 1 Hz–5 MHz. The potential data transmission rates through a raw bit error rate analysis using a pseudorandom bit sequence between 1–1,000 kbps were evaluated. The passband for the tissue was between 1–500 kHz, characterizing it as a low-pass filter. Bit streams below 10 kbps had an error rate of <10%>500 kbps. The results suggest that this fungal tissue could serve as a low-speed data transmission medium specifically for low-pass signals related to general human health such as ECG, EEG, EMG signals as well as temperature and glucose monitoring. While more research is necessary to understand the morphological and species-specific impacts on signal propagation between different fungi, tissues from the fungus <italic>C. lunata</i> and those with similar properties could potentially serve as a component in low-frequency biosensors and signal transmission.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":"9 2","pages":"206-213"},"PeriodicalIF":3.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10720524","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144117314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advanced Microdosimetric and Neurofunctionalized Multiphysics on Stem Cells Models Under Microsecond Pulse Stimulation","authors":"Sara Fontana;Laura Caramazza;Micol Colella;Noemi Dolciotti;Alessandra Paffi;Victoria Moreno Manzano;Claudia Consales;Francesca Apollonio;Micaela Liberti","doi":"10.1109/JERM.2024.3468024","DOIUrl":"https://doi.org/10.1109/JERM.2024.3468024","url":null,"abstract":"<bold>Objectives:</b> in recent biomedical applications for regenerative and tissue engineering, the use of electric and magnetic fields is increasingly exploited. Among the wide application range, an innovative treatment for Spinal Cord Injury (SCI) is urgent. The European project RISEUP proposes a novel device development, that will provide highly intense microsecond pulsed electric fields (μsPEFs) to stimulate stem cells differentiation towards neuronal phenotypes, through an electroporation-driven process, and regenerate the lesioned tissue. Within RISEUP the use of advanced computational models is crucial to predict the cellular functional response through microdosimetry studies. <bold>Technology or Method:</b> a multiphysic neuro-functionalized computational model has been built, using a realistic induced Neuronal Stem Cell (iNSC) model (a iNSC digital twin), to predict the effect of μsPEFs stimulation on both neuronal response and pore formation dynamics. <bold>Results:</b> considering a 100-μsPEF and an intensity of 30 kV/m, the pore density can reach up to 10<sup>14</sup> m<sup>−2</sup> over the plasma membrane, with a consequent hyperpolarization and a phase shift of the neuronal firing. Whereas, where the pore density remains at its default value 10<sup>9</sup> m<sup>−2</sup>, the neuronal response is slightly affected in spikes frequency and shape, but still maintaining its firing functions. <bold>Conclusions</b>: this study provides an innovative multiphysics implementation on a realist 2D iNSC model, that has demonstrated the 100-μsPEF influence on the neurodynamic response. <bold>Clinical or Biological Impact:</b> the results obtained give powerful insights for further <italic>in vitro</i> and <italic>in vivo</i> experiments, that will validate the use of the device proposed within RISEUP for SCI regeneration.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":"9 2","pages":"173-182"},"PeriodicalIF":3.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144117316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Size-Adaptive Occipital 18-Channel Receive-Only RF Coil for 3T MRI","authors":"William Mathieu;Milica Popović;Reza Farivar","doi":"10.1109/JERM.2024.3465354","DOIUrl":"https://doi.org/10.1109/JERM.2024.3465354","url":null,"abstract":"The performance of a conformal occipital receive-only radio-frequency (RF) array is demonstrated at 3T. The ultimate aim of this larger coil is to improve whole-brain magnetic resonance imaging (MRI) regardless of a person's head size and shape. The occipital array contains 18-channels built on a 3D-printed 3-mm thick thermoplastic polyurethane (TPU) plate, which acts as a flexible substrate. To show the performance improvements of our design a comparative study was performed where three differently shaped phantoms were used when imaging by our occipital array then by a standard rigid 64-channel head product coil (posterior 40-channel section only). Signal-to-noise-ratio (SNR) and noise correlation performance were evaluated. Compared to the product coil, the flexible occipital array improved mean SNR by 2.8×. Noise correlation was comparable to the product coil. These results lead us to conclude that our design represents a viable approach to improve SNR for differently shaped heads and supports the feasibility of a larger 128-channel size-adaptable whole-head array currently in development.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":"9 2","pages":"166-172"},"PeriodicalIF":3.0,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144117318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Unit Cell Density on Grid and Stripe Metasurfaces for MRI Receive Enhancement","authors":"Robert Kowal;Lucas Knull;Ivan Vogt;Max Joris Hubmann;Daniel Düx;Bennet Hensen;Frank Wacker;Oliver Speck;Holger Maune","doi":"10.1109/JERM.2024.3458078","DOIUrl":"https://doi.org/10.1109/JERM.2024.3458078","url":null,"abstract":"Metasurfaces enable magnetic resonance imaging (MRI) without cables inside the bore by locally improving the sensitivity of scanner-integrated receive coils. This study systematically evaluates a novel grid design to provide signal enhancement for patient imaging. The potential of the proposed metasurface grid design was analyzed regarding its unit cell density and compared with stripe type metasurfaces. The effects were examined in-depth by numerical simulation, workbench measurements, and MRI experiments at 3 Tesla. Differences in the signal-to-noise ratio (SNR) using either the integrated body or spine coils were evaluated, as well as the influence of the metasurface orientation. The grid design provided a favorable eigenmode usable for MR imaging, where it has shown significantly less dependence on orientation, compared to stripe metasurfaces. With the densest grid, more than 26% higher SNR than its most spaced design was achieved. Combining the metasurface for imaging with the spine coil proved to be superior to the body coil. Applying the metasurface for knee imaging, the SNR was locally enhanced by more than 10-fold compared to the scan with only the spine coil. The high-density grid metasurfaces provided benefits compared to the multitude of designs evaluated. This work provides a comprehensive foundation for future developments of metasurfaces for MRI, whose advantages may be exploited e.g. in the domain of interventional radiology.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":"9 2","pages":"198-205"},"PeriodicalIF":3.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10685136","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144117319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}