IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology最新文献_第10页

Experimental Assessment of Axillary Lymph Node Microwave Tomography Using Anthropomorphic Phantoms 利用拟人象对腋窝淋巴结微波层析成像的实验评价

IF 3.2

IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology Pub Date : 2023-02-13 DOI: 10.1109/JERM.2023.3241777

Matteo Savazzi;Olympia Karadima;David O. Rodriguez Duarte;Jorge Tobon Vasquez;Francesca Vipiana;Panagiotis Kosmas;Carlos A. Fernandes;João M. Felício;Raquel C. Conceição

{"title":"Experimental Assessment of Axillary Lymph Node Microwave Tomography Using Anthropomorphic Phantoms","authors":"Matteo Savazzi;Olympia Karadima;David O. Rodriguez Duarte;Jorge Tobon Vasquez;Francesca Vipiana;Panagiotis Kosmas;Carlos A. Fernandes;João M. Felício;Raquel C. Conceição","doi":"10.1109/JERM.2023.3241777","DOIUrl":"https://doi.org/10.1109/JERM.2023.3241777","url":null,"abstract":"We assess the application of microwave tomography (MWT) for the detection of axillary lymph nodes (ALNs) in breast cancer patients. We numerically study the effects of limiting angular view in axillary MWT, as probes can only be placed on a limited arc around the axillary region. We also numerically study the possibility of increasing the amount of retrievable information by acquiring data in two consecutive steps, with a single antenna set in two different angular positions. We finally experimentally test axillary MWT on anthropomorphic phantoms with different levels of anatomical fidelity, and different ALN positions. Our MWT system (0.8–2.5 GHz) employs six monopole antennas placed on a single transverse plane, facing the axillary region. The reconstruction algorithm implements the distorted Born iterative method, combined with the two-step iterative shrinkage/thresholding for the inversion (DBIM-TwIST). Our numerical results i) highlight the challenges associated with the limited angular view, and ii) show that performing two-step angular measurements enhances imaging results, suggesting that rotating the antenna set between consecutive measurements is an effective means to increase the retrievable information in ALN MWT. Our experimental results show that our MWT system can detect an ALN in different positions. To the best of our knowledge this is the first paper to assess ALN MWT in a realistic 3-D experimental scenario.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2023-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50382710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Study of Handgrip Force Prediction Scheme Based on Electrical Impedance Myography 基于电阻抗肌电的握力预测方案研究

IF 3.2

IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology Pub Date : 2023-02-10 DOI: 10.1109/JERM.2023.3241769

Pan Xu;Xudong Yang;Wei Ma;Wanting He;Željka Lučev Vasić;Mario Cifrek;Yueming Gao

{"title":"A Study of Handgrip Force Prediction Scheme Based on Electrical Impedance Myography","authors":"Pan Xu;Xudong Yang;Wei Ma;Wanting He;Željka Lučev Vasić;Mario Cifrek;Yueming Gao","doi":"10.1109/JERM.2023.3241769","DOIUrl":"https://doi.org/10.1109/JERM.2023.3241769","url":null,"abstract":"Handgrip force prediction is widely used in the rehabilitation of the arm and prosthetic control. To investigate the effects of different measurement positions and feature parameters on the results of handgrip force prediction, a model based on electrical impedance myography (EIM) and long short-term memory (LSTM) networks was proposed to compare and determine a better scheme for handgrip force prediction. We conducted the signal acquisition experiments of impedance and handgrip force on the anterior forearm muscles and brachioradialis muscle. Afterwards, three evaluation metrics were introduced to compare the prediction results of various models, and the variability between models was analyzed using paired sample t-tests. The results showed that the model of handgrip force prediction based on anterior forearm muscles exhibited better performance in predicting. The evaluation metrics of \u0000<inline-formula><tex-math>$mathbf {R^{2}}$</tex-math></inline-formula>\u0000, explained variance score (EVS) and normalized mean square error (NMSE) for the model fusing the feature parameters resistance (R) and reactance (X) were 0.9023, 0.9173 and 0.0114, respectively. Therefore, the feature parameters fusing R and X are the optimal input for the handgrip force prediction model. The anterior forearm muscles are the preferred position for impedance measurement over the brachioradialis muscle. This paper validated the feasibility of EIM for handgrip force prediction and provided a new reference and implementation scheme for muscle rehabilitation training and prosthetic control.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2023-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50308344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Candida Cell Heterogeneity Measured With a Microwave Flow Cytometer 用微波流式细胞仪测定念珠菌细胞的异质性

IF 3.2

IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology Pub Date : 2023-02-02 DOI: 10.1109/JERM.2023.3239557

Neelima Dahal;Carl Ehrett;Jeffrey A. Osterberg;Ralu Divan;Pingshan Wang

{"title":"Candida Cell Heterogeneity Measured With a Microwave Flow Cytometer","authors":"Neelima Dahal;Carl Ehrett;Jeffrey A. Osterberg;Ralu Divan;Pingshan Wang","doi":"10.1109/JERM.2023.3239557","DOIUrl":"https://doi.org/10.1109/JERM.2023.3239557","url":null,"abstract":"Heterogeneity is an important property of a cell population. It is an intrinsic driving force behind biological evolution and a main challenge for effective disease treatment, such as precision solid cancer therapy. Various “omics” methods, mass spectroscopy-based techniques, and flow cytometry have been developed for cell heterogeneity characterization. But current methods are either low throughput or invasive. In this work, we develop a simple microwave flow cytometer to measure single \u0000<italic>C. tropicalis\u0000 and \u0000<italic>C. albicans\u0000, which are two of the most important \u0000<italic>Candida\u0000 yeasts that cause candidemia disease. The obtained scatter plots of cell permittivity for both the species show a colinear relationship for cells of different volumes, which indicates a largely conserved cell molecular composition profile despite heterogeneous cell sizes. We also apply microwave flow cytometer to measure antifungal drug effect on \u0000<italic>C. tropicalis\u0000 and \u0000<italic>C. albicans\u0000 cell population and observe that drugs induce significant heterogeneity increase. The results show that microwave flow cytometry is a promising new method for high throughput and noninvasive characterization of cell heterogeneity. More work is needed, including the determination of biological significance of the observed microwave heterogeneity.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2023-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50238038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lab-On-Chip UHF-Dielectrophoretic Cytometer for Colorectal Cancer Stem Cells Sorting Lab-On-Chip超高频介电式大肠癌干细胞分选仪

IF 3.2

IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology Pub Date : 2023-01-19 DOI: 10.1109/JERM.2023.3234463

Elisa Lambert;Elodie Barthout;Thomas Provent;Remi Manczak;Sofiane Saada;Barbara Bessette;Muriel Mathonnet;Fabrice Lalloué;Claire Dalmay;Arnaud Pothier

{"title":"Lab-On-Chip UHF-Dielectrophoretic Cytometer for Colorectal Cancer Stem Cells Sorting","authors":"Elisa Lambert;Elodie Barthout;Thomas Provent;Remi Manczak;Sofiane Saada;Barbara Bessette;Muriel Mathonnet;Fabrice Lalloué;Claire Dalmay;Arnaud Pothier","doi":"10.1109/JERM.2023.3234463","DOIUrl":"https://doi.org/10.1109/JERM.2023.3234463","url":null,"abstract":"In this article, we introduce a method to exploit ultra-high dielectrophoresis (UHF-DEP) with a microfluidic radio frequency device able to sort biological cells by deflecting the trajectory of the targeted population in a continuous flow. This study highlights the capability of a high frequency lab-on-chip implemented UHF-DEP cytometer to isolate cancer stem cells (CSCs). Actually, CSCs sorting by an efficient, fast and low-cost method remains an issue. Above 20 MHz, the intracellular dielectric properties of cells determine the dielectrophoretic behavior of cells and is then very sensitive to the cell cytoplasm content. The proposed cell sorting principle exploits the combination of the fluidic drag and the repulsive dielectrophoretic forces in order to isolate CSCs hidden within differentiated cancer cells. We previously demonstrated the UHF-DEP behavior of cells, as a new type of electromagnetic biomarkers to discriminate cancer stem cells among a tumor population from colorectal cancer cell line.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2023-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50238037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Millimeter-Wave Pulsed Heating in Vitro: Effect of Pulse Duration 毫米波脉冲体外加热：脉冲持续时间的影响

IF 3.2

IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology Pub Date : 2023-01-06 DOI: 10.1109/JERM.2022.3229738

Rosa Orlacchio;Yann Le Page;Yves Le Dréan;Maxim Zhadobov

{"title":"Millimeter-Wave Pulsed Heating in Vitro: Effect of Pulse Duration","authors":"Rosa Orlacchio;Yann Le Page;Yves Le Dréan;Maxim Zhadobov","doi":"10.1109/JERM.2022.3229738","DOIUrl":"https://doi.org/10.1109/JERM.2022.3229738","url":null,"abstract":"The aim of this work is to compare the response of A375 melanoma cells following 90 min of exposure to trains of 1.5 or 6 s millimeter-waves (MMW)-induced thermal pulses with the same temperature dynamics. Phosphorylation of heat shock protein 27 (HSP27) and activation of cleaved Caspase-3 were used as markers of cellular stress and apoptosis, respectively. Immunofluorescence was used to observe and precisely quantify the cellular response as a function of the spatial distribution within the exposed area. Results show that cellular response was stronger when cells were exposed to a train of 1.5 s compared to 6 s heat pulses despite the same average temperature dynamics. Cellular apoptosis induced by 1.5 s pulses was about 50% greater compared to the one induced by 6 s pulses in the area of maximal thermal stress. Similarly, HSP27 phosphorylation was approximately 20% stronger than the one induced by 6 s pulses, and mainly focused within a small area of a few mm\u00002\u0000. Cellular response to MMW induced by pulsed heating does not only depend on the peak, average, and minimum temperature. It is a function of combination of the pulse parameters, including duration, peak power, and period. MMW-induced heat pulses can be efficiently used to induce cellular stress and apoptosis in melanoma cells as a promising innovative tool for the treatment of superficial skin cancer. Adaptative therapies might be envisaged by tuning the pulse shape as a function of the desired effect.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2023-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50382709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wirelessly Powered 3-D Printed Headstage Based Neural Stimulation System for Optogenetic Neuromodulation Application 用于光遗传学神经调控应用的基于无线驱动的3D打印头戴式神经刺激系统

IF 3.2

IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology Pub Date : 2023-01-03 DOI: 10.1109/JERM.2022.3225972

Dipon K. Biswas;Nabanita Saha;Ifana Mahbub

{"title":"Wirelessly Powered 3-D Printed Headstage Based Neural Stimulation System for Optogenetic Neuromodulation Application","authors":"Dipon K. Biswas;Nabanita Saha;Ifana Mahbub","doi":"10.1109/JERM.2022.3225972","DOIUrl":"https://doi.org/10.1109/JERM.2022.3225972","url":null,"abstract":"This work presents a miniaturized wireless power transfer (WPT) system integrated with a neuromodulation headstage for duty-cycled optical stimulation of freely moving rodents. The proposed WPT system is built using the commercially available off-the-shelf components (COTS) for the optogenetic neuromodulation system consisting of a bridge rectifier, a DC-DC converter, an oscillator circuit, an LED driver, and a μLED. The total power consumption of the stimulation system is 14 mW which is provided using the WPT method. The WPT system includes a novel transmitter (TX) coil implemented on a printed circuit board (PCB), and a solenoid receiver (RX) coil wrapped around a customized 3-D printed headstage. The proposed TX coil is designed in such a way that the magnetic field all across the TX coil is sufficient to provide the required power to the optical stimulation system that is worn as a headstage by the freely moving rat. The headstage device's dimension is 18.75 mm × 21.95 mm, weighing 4.75 g. The ratio of the weight of the headstage and rat is 4.75:300. The proposed system is able to achieve a maximum overall efficiency of ∼63% at 5 cm separation between the TX and RX coils, where the maximum power transfer efficiency (PTE) of the WPT system is ∼88% and the power conversion efficiency (PCE) of the rectifier is 71.6%. The proposed system with reconfigurable stimulation frequency is suitable for exciting different brain areas for long-term health monitoring.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2023-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50410437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stroke Diagnosis Using Microwave Techniques: Review of Systems and Algorithms 利用微波技术进行中风诊断：系统和算法综述

IF 3.2

IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology Pub Date : 2022-12-20 DOI: 10.1109/JERM.2022.3227724

Lei Guo;Abdulrahman S. M. Alqadami;Amin Abbosh

引用次数: 4

Area-Averaged Transmitted and Absorbed Power Density on a Realistic Ear Model 真实耳朵模型上的面积平均发射和吸收功率密度

IF 3.2

IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology Pub Date : 2022-12-20 DOI: 10.1109/JERM.2022.3225380

Ante Lojić Kapetanović;Giulia Sacco;Dragan Poljak;Maxim Zhadobov

{"title":"Area-Averaged Transmitted and Absorbed Power Density on a Realistic Ear Model","authors":"Ante Lojić Kapetanović;Giulia Sacco;Dragan Poljak;Maxim Zhadobov","doi":"10.1109/JERM.2022.3225380","DOIUrl":"https://doi.org/10.1109/JERM.2022.3225380","url":null,"abstract":"At millimeter waves (MMW), the current state of research in computational dosimetry is mainly relying on flat-surface tissue-equivalent models to simplify the exposure assessment by disregarding geometrical irregularities characteristic of conformal surfaces on realistic models. However, this can lead to errors in estimation of dosimetric quantities on non-planar body parts with local curvature radii comparable to the wavelength of the incident field. In this study, we address this problem by developing an averaging technique for the assessment of the absorbed power density (\u0000<inline-formula><tex-math>$S_{text{ab}}$</tex-math></inline-formula>\u0000) on the anatomically-accurate electromagnetic (EM) model of the human ear. The dosimetric analysis is performed for the plane-wave exposure at 26 and 60 GHz, and the accuracy of the proposed method is verified by using two commercial EM software. Furthermore, we compare the two definitions of \u0000<inline-formula><tex-math>$S_{text{ab}}$</tex-math></inline-formula>\u0000 provided in the international guidelines and standards for limiting exposure to EM fields above 6 GHz. Results show marginal relative differences between the obtained values from the two different definitions (within about 6 %) in all considered scenarios. On the other hand, in comparison to flat models, the spatial maximum \u0000<inline-formula><tex-math>$S_{text{ab}}$</tex-math></inline-formula>\u0000 on the ear is up to about 20 % larger regardless of definition. These findings demonstrate a promising potential of the proposed method for the assessment of \u0000<inline-formula><tex-math>$S_{text{ab}}$</tex-math></inline-formula>\u0000 on surfaces of anatomical models at frequencies upcoming for the 5th generation (5G) wireless networks and beyond","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50410307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Microwave Heating for the Conservation of Cultural Heritage Assets: A Review of Main Approaches and Challenges 微波加热保护文化遗产资产：主要途径和挑战综述

IF 3.2

IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology Pub Date : 2022-12-14 DOI: 10.1109/JERM.2022.3225710

Stefania Romeo;Olga Zeni

{"title":"Microwave Heating for the Conservation of Cultural Heritage Assets: A Review of Main Approaches and Challenges","authors":"Stefania Romeo;Olga Zeni","doi":"10.1109/JERM.2022.3225710","DOIUrl":"https://doi.org/10.1109/JERM.2022.3225710","url":null,"abstract":"<italic>Objectives:\u0000 The cultural heritage (CH) represents the proof of human achievements from the past in terms of historical and technological progress. One of the main issues regarding CH preservation is the bio-deterioration phenomenon which arises from biological colonization of artistic materials with consequent aesthetic, chemical and structural damage. The most common disinfestation methods are based on mechanical, chemical, biological or physical treatments. Among the physical methods, microwave heating has high potentialities, but its application is not a standard. Here we reviewed relevant literature on the use of microwave heating for the disinfestation of artworks from biodeteriogens. \u0000<italic>Method:\u0000 We performed a systematic literature search, identified twenty relevant publications, and extracted relevant information. \u0000<italic>Results:\u0000 Microwave heating resulted effective for total disinfestation of various infesting agents on several materials, rapid, safe for operators and the environment. However, we highlighted the lack of a systematic approach to the planning of artworks treatment with microwave heating and developed operative guidelines that include dielectric characterization of materials, prediction and control of electric field distribution in the artwork, identification of lethal doses for infesting agents. \u0000<italic>Impact:\u0000 The proposed approach might contribute to boost the use of this promising, non-invasive, and safe technology for artworks conservation.","PeriodicalId":29955,"journal":{"name":"IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology","volume":null,"pages":null},"PeriodicalIF":3.2,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50238035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

2022 Index IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology Vol. 6 2022年索引IEEE医学与生物学电磁学、RF和微波杂志第6卷

IF 3.2

IEEE Journal of Electromagnetics RF and Microwaves in Medicine and Biology Pub Date : 2022-12-13 DOI: 10.1109/JERM.2022.3227877

引用次数: 0