ACS Nanoscience Au最新文献_第2页

Copper-Based Nanostructures as Peroxidase Mimics: Elucidating the Roles of Shape, Composition, and Chloride Ion Modulation 铜基纳米结构作为过氧化物酶模拟物：阐明形状、组成和氯离子调制的作用

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-10-13 DOI: 10.1021/acsnanoscienceau.6c00146

Ghazaleh Salmanian, Lihua Zhang, Mourad Benamara, Abigail Bell, Jingyi Chen

{"title":"Copper-Based Nanostructures as Peroxidase Mimics: Elucidating the Roles of Shape, Composition, and Chloride Ion Modulation","authors":"Ghazaleh Salmanian, Lihua Zhang, Mourad Benamara, Abigail Bell, Jingyi Chen","doi":"10.1021/acsnanoscienceau.6c00146","DOIUrl":"https://doi.org/10.1021/acsnanoscienceau.6c00146","url":null,"abstract":"Nanozymes, artificialenzymes that have emerged as promising alternativesto traditional enzymes, offer high stability, versatility, and easeof production. In this study, we investigated the peroxidase-mimickingactivity of Cu-based nanostructures, including nanoparticles (CuNS)and nanowires (CuNW), as well as Cu–Au alloys and intermetallicnanoparticles. The substrate 3,3′,5,5′-tetramethylbenzidine(TMB) was used to monitor the kinetics. Our results showed that CuNWexhibited 2.1-fold higher activity toward TMB oxidation than CuNS,with a kcat value of 10.0 × 10–4 s–1. The addition of NaCl enhancedcatalytic activity, decreasing the activation energy (Ea) from 15.54 to 11.92 kJ/mol for CuNS and from 14.30to 12.83 kJ/mol for CuNW. The mechanism involves a Cu(I)/Cu(II) cycle,where Cu metal coupling and chloride ions facilitate the reaction.The Cu3Au alloy nanoparticles exhibited 1.8-fold highercatalytic activity than their intermetallic counterparts, with a kcat value of 3.68 × 10–4 s–1 due to differences in their Cu stability.Chloride ions had a positive effect on catalytic activity, lowering Ea values from 30.45 to 16.80 kJ/mol for thealloy and from 37.92 to 32.10 kJ/mol for the intermetallic. Our findingsprovide new insights into the development of nonprecious metal-containingcatalysts as efficient nanozymes for various applications.","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"6 5","pages":"1037–1049"},"PeriodicalIF":7.5,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Quantitative Delineation of the Morphological Heterogeneity of Anisotropic Nanostructures via Machine-Learning-Augmented Electron Microscopy 利用机器学习增强电子显微镜定量描述各向异性纳米结构的形态异质性

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-09-04 DOI: 10.1021/acsnanoscienceau.6c00084

Kenry

{"title":"Quantitative Delineation of the Morphological Heterogeneity of Anisotropic Nanostructures via Machine-Learning-Augmented Electron Microscopy","authors":"Kenry","doi":"10.1021/acsnanoscienceau.6c00084","DOIUrl":"https://doi.org/10.1021/acsnanoscienceau.6c00084","url":null,"abstract":"Precise synthesis and engineering of homogeneous anisotropicnanostructuresare essential to realize their shape-dependent physicochemical propertiesfor different applications. However, due to the difficulty in controllingfactors influencing nucleation and growth, many reported anisotropicnanostructures exhibit substantial heterogeneity, particularly intheir size and shape distributions. Current methods for assessingnanostructure heterogeneity, whether ensemble- or single-particle-basedtechniques, are limited in the types of readout information, resolution,and throughput. Although machine-learning-assisted microscopy approacheshave facilitated nanomaterial heterogeneity characterization to acertain extent, strategies that transform microscopy images into quantitativemorphology feature spaces for population-level heterogeneity analysisremain underexplored. Herein, a quantitative approach combining transmissionelectron microscopy (TEM) imaging with machine learning is demonstratedfor delineating the projected morphological heterogeneity of anisotropicnanostructures. Following supervised pixel classification and thresholding,TEM images are converted to probability maps and image masks, fromwhich a series of interpretable projected size- and shape-relatedmorphological descriptors are extracted. Dimensionality reductionand unsupervised clustering are subsequently employed to analyze theacquired morphological feature space and identify putative nanostructuresubpopulations based on morphological similarities or differences.Feature scoring is further performed to identify descriptors associatedwith variations among nanostructure subpopulations while consideringcorrelations among related geometric parameters. This study establishesa machine-learning-augmented framework for quantitative and objectiveanalysis of anisotropic nanostructure heterogeneity and provides afoundation for future integration with synthesis metadata and predictivemodeling approaches.","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"6 5","pages":"933–943"},"PeriodicalIF":7.5,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fundamental Understanding of Photon- and Phonon-Powered Catalysis 光子和声子催化的基本认识

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-09-01 DOI: 10.1021/acsnanoscienceau.6c00108

Jiakun Wang, Lu Wang

引用次数: 0

Challenges and Advances in Elucidating the Electronic Circular Dichroism of Crystalline Materials through First-Principles Calculations 利用第一性原理计算阐明晶体材料电子圆二色性的挑战与进展

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-10-09 DOI: 10.1021/acsnanoscienceau.6c00116

Wenkai Zhao, Xinyu Sun, Sehrish Gull, Jiabin Chen, Bing Sun, Yu-Wu Zhong, Hao-Li Zhang, Haibo Ma, Guankui Long

{"title":"Challenges and Advances in Elucidating the Electronic Circular Dichroism of Crystalline Materials through First-Principles Calculations","authors":"Wenkai Zhao, Xinyu Sun, Sehrish Gull, Jiabin Chen, Bing Sun, Yu-Wu Zhong, Hao-Li Zhang, Haibo Ma, Guankui Long","doi":"10.1021/acsnanoscienceau.6c00116","DOIUrl":"https://doi.org/10.1021/acsnanoscienceau.6c00116","url":null,"abstract":"The electronic circulardichroism (ECD) of crystalline materialsis governed by physical effects that are absent in isolated-moleculetheory. Bloch-state delocalization makes position-operator matrixelements ill-defined and requires Berry-connection formulations ofthe periodic optical-activity response, while excitonic effects redistributeoscillator strength across the band gap. This Perspective criticallysurveys the hierarchy of first-principles methods that have been establishedto address these challenges. Molecular-cluster time-dependent densityfunctional theory (TDDFT) provides chemical intuition and mechanisticinsight but cannot represent the complete periodic response and canunderestimate long-range crystal field effects. Periodic independent-particlecalculations incorporate the crystalline environment and band-geometricresponse, whereas self-consistent coupled-perturbed approaches additionallyinclude crystal-orbital relaxation. Adaptive Brillouin-zone samplingcan accelerate convergence for localized one-particle contributions,although nonuniform meshes complicate momentum conservation in thecorrelated treatments. GW-BSE provides a rigorous framework for excitonicoptical activity, whereas maximally localized Wannier function interpolationefficiently converges the DFT-level periodic quantities used to analyzethe band-geometric response. A generally validated workflow that combinesthe BSE-level excitonic response with all geometric and interpolationingredients has not yet been established. Finally, we discuss openchallenges including fully relativistic treatments of chiral rare-earthhalide perovskites and single-crystal anisotropy measurements.","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"6 5","pages":"700–711"},"PeriodicalIF":7.5,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transient Electroluminescence Delay and Capacitive Charging of the Hole Transport Layer in Quantum Dot Light-Emitting Diodes 量子点发光二极管空穴传输层的瞬态电致发光延迟与容性充电

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-08-29 DOI: 10.1021/acsnanoscienceau.6c00100

Conan Huang, Nuri Oh, Moonsub Shim

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Thermal-Induced Morphological Evolution of Highly Ordered Gold Nanoarrays for Ultrasensitive Digital Biodetection 用于超灵敏数字生物检测的高有序金纳米阵列的热诱导形态演化

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-09-25 DOI: 10.1021/acsnanoscienceau.6c00110

Leyi Sun, Xiangfu Hu, Shasha Li, Yixuan Yao, Fuqiang Yan, Zhenda Lu

{"title":"Thermal-Induced Morphological Evolution of Highly Ordered Gold Nanoarrays for Ultrasensitive Digital Biodetection","authors":"Leyi Sun, Xiangfu Hu, Shasha Li, Yixuan Yao, Fuqiang Yan, Zhenda Lu","doi":"10.1021/acsnanoscienceau.6c00110","DOIUrl":"https://doi.org/10.1021/acsnanoscienceau.6c00110","url":null,"abstract":"Digital biodetectionhas revolutionized clinical research and diagnosticsby utilizing single-molecule counting to overcome the limitationsof traditional analog signals. While plasmon-enhanced fluorescence(PEF) offers a rapid, enzyme-free method for signal amplification,the inconsistent distribution of chemically synthesized nanoparticleson sensing interfaces remains a major barrier to detection robustness.In this study, we address this challenge by developing highly orderedgold nanoparticle arrays using nanoimprint lithography and physicalvapor deposition. We systematically investigated the effect of thermalannealing temperature on the morphological and optical evolution ofthese arrays. Our findings demonstrate that high-temperature thermalannealing restructures as-deposited Au nanodisks into compact, quasi-sphericalnanoparticles while driving grain growth and enhanced crystallinecoherence. This structural refinement blue-shifts the localized surfaceplasmon resonance (LSPR) by approximately 100 nm, significantly optimizingspectral coupling with Cy5 fluorophores. Arrays annealed at 750 °Cyield strong dark-field scattering, excellent spectral overlap withthe Cy5 emission band, and superior particle–substrate adhesion,together generating the maximum fluorescence enhancement factor. Consequently,the optimized nanoarrays achieve a one-order-of-magnitude boost indetection sensitivity, enabling an attomolar-level limit of detection(LOD) for model DNA targets in buffer. Furthermore, the platform reliablydetects temporally resolved single-molecule photobleaching eventseven in complex biological matrices such as 1 pM target in fetal bovineserum (FBS). Overall, this work presents a robust and scalable fabricationstrategy for high-performance plasmonic arrays tailored for digitalbioanalysis.","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"6 5","pages":"1000–1008"},"PeriodicalIF":7.5,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Opportunities toward Scalable Domain-Wall-Based Spintronic Devices 面向可扩展的基于畴壁的自旋电子器件的机遇

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-09-09 DOI: 10.1021/acsnanoscienceau.6c00113

Jae-Chun Jeon, Lukas Fischer, Yung-Cheng Li, Renata Lei, Stuart S. P. Parkin

{"title":"Opportunities toward Scalable Domain-Wall-Based Spintronic Devices","authors":"Jae-Chun Jeon, Lukas Fischer, Yung-Cheng Li, Renata Lei, Stuart S. P. Parkin","doi":"10.1021/acsnanoscienceau.6c00113","DOIUrl":"https://doi.org/10.1021/acsnanoscienceau.6c00113","url":null,"abstract":"Since its initial proposal in 2004, racetrack memory,which utilizescurrent-induced motion of domain walls within a magnetic nanowire,has evolved from a conceptual spintronic device into a mature researchplatform supported by major advances in materials engineering, nanotechnology,domain-wall physics, and spin-torque mechanisms. Yet, practical racetrackmemory or logic remains challenging. The field has entered a new statein which the dominant challenges are no longer associated with drivingdomain walls or understanding the fundamental mechanisms behind them,but with achieving reliable device operation and fabrication of practicalnanoscale devices. Key bottlenecks include the electrical readoutof nanoscopic racetrack devices, the integration of magnetic tunneljunctions, the control of stochastic domain-wall behavior, positioningaccuracy, and scalability toward three-dimensional (3D) architectures.We briefly summarize the current status of the field and discuss howthese challenges redefine research priorities while creating opportunitiesfor advances in electrical readout, 3D device integration, and noveldomain-wall-based computing architectures. By highlighting emergingdirections in device engineering and advanced characterization, weoutline pathways toward translating laboratory-scale demonstrationsinto scalable, manufacturable spintronic memory and logic technologies.","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"6 5","pages":"685–699"},"PeriodicalIF":7.5,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Domain-Encoded Chirality in Carbon Nanomaterials from Structural Origins and Chiroptical Responses to Biological Effects 结构来源的碳纳米材料的域编码手性和对生物效应的热响应

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-09-22 DOI: 10.1021/acsnanoscienceau.6c00133

Yichen Liu, Wei Zhang, Yao Huo, Yichun Wang

{"title":"Domain-Encoded Chirality in Carbon Nanomaterials from Structural Origins and Chiroptical Responses to Biological Effects","authors":"Yichen Liu, Wei Zhang, Yao Huo, Yichun Wang","doi":"10.1021/acsnanoscienceau.6c00133","DOIUrl":"https://doi.org/10.1021/acsnanoscienceau.6c00133","url":null,"abstract":"Chirality offers a powerful but underdeveloped designprinciplefor regulating the optical, molecular, and biological behavior ofcarbon nanomaterials. Unlike small molecules, whose handedness istypically defined by discrete stereocenters, carbon nanomaterialscan encode chirality across multiple structural domains, includingthe carbon framework, chemically accessible surfaces and interfaces,and supramolecular assemblies. These domain-encoded chiralities differin how they are generated, how they produce chiroptical and electronicresponses, and how they are presented at nano–bio interfaces.In this Review, we organize chiral carbon nanomaterials, includingcarbon dots, graphene quantum dots, graphene oxide derivatives, carbonnanotubes, fullerenes, graphene nanoribbons, and hybrid assemblies,into framework-encoded, surface/interface-derived, and supramolecularchirality. We examine how each category produces circular dichroism,circularly polarized luminescence, fluorescence, and electronic responses,and how these properties influence biointerface interactions and biologicalor bioanalytical functions. Representative studies span molecularrecognition, sensing and imaging, membrane and extracellular-matrixtransport, drug delivery, and selected therapeutic effects, includingphototherapy, antimicrobial activity, and protein-homeostasis regulation.We further identify major barriers to predictive design, includinglimited structural control, incomplete assignment of chiroptical origins,insufficient separation of chirality effects from nonchiral physicochemicalvariables, and limited validation in realistic biological environments.By connecting structural origin, optical expression, and biointerfaceeffect, this Review provides a framework for mechanistically interpretingand designing chiral carbon nanomaterials for biological and bioanalyticalapplications.","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"6 5","pages":"770–794"},"PeriodicalIF":7.5,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In Situ Growth of Copper Phenylacetylide Nanobelts on Copper Foil for Enhanced Electroreduction of CO2 to Multi-Carbon Products 在铜箔上原位生长苯乙基铜纳米带以促进CO2电还原成多碳产物

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-07-17 DOI: 10.1021/acsnanoscienceau.6c00082

Shijin Yang, Qi Fang, Jing Tang, Jianping Ge

{"title":"In Situ Growth of Copper Phenylacetylide Nanobelts on Copper Foil for Enhanced Electroreduction of CO2 to Multi-Carbon Products","authors":"Shijin Yang, Qi Fang, Jing Tang, Jianping Ge","doi":"10.1021/acsnanoscienceau.6c00082","DOIUrl":"https://doi.org/10.1021/acsnanoscienceau.6c00082","url":null,"abstract":"Copper-based metal–organic composites are promisingcatalystsfor electrochemical CO2 reduction reaction (eCO2RR). However, it is difficult to prepare stable Cu+ activesites in a controllable way and maintain them in the catalytic reduction.In this work, a (CuPA-Ag)/Cu electrode was prepared by the ion sputteringof Ag NPs on the copper foil, followed by the in situ growth of AgNP-grafted CuPA NBs on its surface. The electrode possessed a largeamount of Cu+ active sites due to the strong σ-donationand π-backdonation interactions between the phenylacetyleneligand and Cu+, which significantly improved the catalyticperformances. Using the optimized electrode and reaction conditions,the eCO2RR achieved Faraday efficiencies of 44.5% for C2H4 and 56.5% for C2+ products in theH cell. With periodic supplementation of the CO2 source,the eCO2RR maintained an FEC2H4 above 40% for 11 h. Its superior catalytic performance originatedfrom the densely stacked nanobelt structures with a large electrochemicalsurface area and enhanced electron transfer, the synergistic effectbetween Ag and Cu+ to promote the CO2 absorptionand C–C coupling, and the hydrophobicity of CuPA to inhibitthe hydrogen evolution reaction.","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"6 5","pages":"923–932"},"PeriodicalIF":7.5,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanotechnology to Engineer the Surface of Immune Cells 纳米技术改造免疫细胞表面

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-08-18 DOI: 10.1021/acsnanoscienceau.6c00056

Zhenjiang Zhang, Michael R. King

引用次数: 0