ACS Nanoscience Au最新文献

Addition–Fragmentation–Transfer Monitored by Fluorescence Lifetime Imaging Microscopy 荧光寿命成像显微镜监测添加-破碎-转移

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-08-28 DOI: 10.1021/acsnanoscienceau.6c00066

M. K. Jutze, Ellie Haljun, Mao Komura, Nanthicha Thajai, Reika Katsumata

{"title":"Addition–Fragmentation–Transfer Monitored by Fluorescence Lifetime Imaging Microscopy","authors":"M. K. Jutze, Ellie Haljun, Mao Komura, Nanthicha Thajai, Reika Katsumata","doi":"10.1021/acsnanoscienceau.6c00066","DOIUrl":"https://doi.org/10.1021/acsnanoscienceau.6c00066","url":null,"abstract":"Radically activateddynamic covalent bonds can enable reprocessable,thus more sustainable, polymeric materials, but conventional characterizationapproaches limit understanding of atomic-scale rearrangements. Specifically,the addition–fragmentation–transfer (AFT) pathway hasbeen characterized by bulk-scale changes in mechanical properties;attempts to probe the exchange on a atomic scale are limited. Traditionalspectroscopic methods cannot detect AFT because the overall bondingenvironment is unchanged before and after exchange with a very short-livedintermediate. To this end, this study uses fluorescence lifetime imagingmicroscopy (FLIM) to probe local AFT bond exchange via nondestructivecharacterization. Herein, allyl sulfide AFT in acrylate polymer thinfilms is monitored by FLIM over time, leveraging the sensitivity offluorescence lifetime to nearby bond rearrangement through a seriesof control systems. Notably, FLIM reveals a continuing AFT cascadebeyond the typical time scale when mechanical property change saturates.We anticipate applying these findings to other hard-to-access phenomena,as well as a mechanistic understanding of the environmental dependenceof fluorescence lifetime.","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"6 5","pages":"863–868"},"PeriodicalIF":7.5,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spin-Uniform Nanodiamond Quantum Sensors for Reproducible Intracellular Thermometry 用于可重复细胞内温度测量的自旋均匀纳米金刚石量子传感器

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-10-06 DOI: 10.1021/acsnanoscienceau.6c00068

Chihiro Suzuki, Tamami Yanagi, Risa Ujiie, Masanori Fujiwara, Izuru Ohki, Hiroshi Abe, Shinobu Onoda, Takeshi Ohshima, Norikazu Mizuochi, Kiichi Kaminaga, Ryuji Igarashi

{"title":"Spin-Uniform Nanodiamond Quantum Sensors for Reproducible Intracellular Thermometry","authors":"Chihiro Suzuki, Tamami Yanagi, Risa Ujiie, Masanori Fujiwara, Izuru Ohki, Hiroshi Abe, Shinobu Onoda, Takeshi Ohshima, Norikazu Mizuochi, Kiichi Kaminaga, Ryuji Igarashi","doi":"10.1021/acsnanoscienceau.6c00068","DOIUrl":"https://doi.org/10.1021/acsnanoscienceau.6c00068","url":null,"abstract":"Nanodiamond quantumsensors have been regarded as promising probesfor cellular thermometry, but their poor sensor-to-sensor reproducibilityhas hindered practical implementation. In cellular measurements, theresulting temperature-readout offsets can be mistaken for real cell-to-celltemperature differences, limiting quantitative comparison. Here, weshow that spin-uniform nitrogen vacancy (NV)-rich nanodiamonds canbe produced via postenrichment oxidative size reduction, which removesdefective surface layers while improving crystallinity. Compared withnanodiamonds prepared by conventional mechanical milling before NVenrichment, the particle-to-particle spread in the temperature-sensitiveD values was reduced by 3.7-fold. The improved NV homogeneity alsoenhanced spin properties: the optically detected magnetic resonancecontrast─a key signal amplitude for sensitivity─increasedby more than 50%. Together, these improvements reduce cell-to-celldispersion in D-derived single-cell temperature readouts to below0.7 K, enabling reliable temperature comparison across cells. Thisapproach advances nanodiamond absolute thermometry toward organelle-scaleintracellular temperature mapping and practical quantum sensing inbiology and medicine.","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"6 5","pages":"869–877"},"PeriodicalIF":7.5,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Construction of Matrix Metalloproteinase-13-Activatable cRGD-Targeted Ratiometric Fluorescent Nanoprobe for Imaging Microscopic Osteosarcoma Lesions and Pulmonary Metastases 基质金属蛋白酶13活化crgd靶向比例荧光纳米探针在骨肉瘤病变及肺转移中的应用

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-09-16 DOI: 10.1021/acsnanoscienceau.6c00092

Yunkai Bao, Shasha Li, Yanqi Wang, Zhenxin Wang, Xiurong Yang

{"title":"Construction of Matrix Metalloproteinase-13-Activatable cRGD-Targeted Ratiometric Fluorescent Nanoprobe for Imaging Microscopic Osteosarcoma Lesions and Pulmonary Metastases","authors":"Yunkai Bao, Shasha Li, Yanqi Wang, Zhenxin Wang, Xiurong Yang","doi":"10.1021/acsnanoscienceau.6c00092","DOIUrl":"https://doi.org/10.1021/acsnanoscienceau.6c00092","url":null,"abstract":"As an important matrix metalloproteinase (MMP) familymember, MMP-13is involved in collagen degradation, extracellular matrix remodeling,and tumor invasion and metastasis, which represents a promising moleculartarget for activity-based detection of osteosarcoma (OS)-associatedlesions. Based on this feature, an MMP-13-activatable, cyclic Arg-Gly-Asp(cRGD)-targeted ratiometric fluorescent nanoprobe, UCNP@PDA@Cy5-pep-cRGD,has been constructed through immobilization of Cy5 modified MMP-13peptide substrate with cRGD motif (Cy5-pep-cRGD) on the polydopaminecoated upconversion nanoparticle (UCNP@PDA). In this nanoprobe, UCNPis employed as a stable upconversion luminescence (UCL) reference,polydopamine (PDA) is used as a low-background fluorescence-quenchingplatform, Cy5 is modified on an MMP-13-cleavable peptide substrateas the responsive signal, and cRGD is further modified on the nanoprobesurface to enhance its tumor-targeted accumulation. The nanoprobehas been systematically characterized, and evaluated for MMP-13 responsiveness,selectivity, ratiometric detection performance, and biological stability.Cellular experiments demonstrate that UCNP@PDA@Cy5-pep-cRGD has strongtargeted accumulation and enzyme-responsive imaging capability towardtumor cells. In vivo and ex vivo imaging experiments further confirm its ability to visualize MMP-13-responsiveactivation in microscopic OS lesions and pulmonary metastases. Thisstrategy enables in situ visualization of MMP-13-mediated nanoprobeactivation for the identification of microscopic OS lesions and pulmonarymetastases.","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"6 5","pages":"976–987"},"PeriodicalIF":7.5,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Colloidal Synthesis of Monodisperse High-Entropy Rare-Earth Oxide Nanoplatelets 单分散高熵稀土氧化物纳米片的胶体合成

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-09-04 DOI: 10.1021/acsnanoscienceau.6c00114

Hanxin Fu, Lingchao Wang, Nachuan Li, Yi Zhou, Siyu Wang, Lianpeng Song, Yakun Yuan, Yifan Sun

{"title":"Colloidal Synthesis of Monodisperse High-Entropy Rare-Earth Oxide Nanoplatelets","authors":"Hanxin Fu, Lingchao Wang, Nachuan Li, Yi Zhou, Siyu Wang, Lianpeng Song, Yakun Yuan, Yifan Sun","doi":"10.1021/acsnanoscienceau.6c00114","DOIUrl":"https://doi.org/10.1021/acsnanoscienceau.6c00114","url":null,"abstract":"High-entropy rare-earth oxides (HE-REOs) offer a broadcompositionalspace for tuning defect chemistry, lattice distortion, and local atomicenvironments, yet their controlled synthesis as monodisperse and structurallywell-defined nanostructures remains challenging. Here, we report acolloidal approach for the synthesis of solution-dispersible, single-crystallineHE-REO nanoplatelets. The ultrathin two-dimensional nanoplateletsadopt a trigonal REO lattice that supports homogeneous multicationincorporation across ternary to denary HE-REO compositions, and asimultaneous multication nucleation and growth pathway is demonstrated.Atomic-resolution imaging, combined with binary-type intensity classification,enables assessment of local chemical ordering, and increasing configurationalentropy drives the system from a nearly random local structure towarda heteroelement-dominated short-range ordered state. High-entropydesign further facilitates the incorporation of chemically dissimilarnonrare-earth cations, expanding the accessible miscibility windowof REO nanostructures. Our work establishes colloidal synthesis asboth a versatile route to monodisperse high-entropy oxide nanostructuresand a model platform for probing and understanding entropy-governedbehavior and functionality in high-entropy materials.","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"6 5","pages":"1009–1020"},"PeriodicalIF":7.5,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Motion Anisotropy of Individual, Unconfined Rod-Like-Shaped Salmonella Typhimurium Bacteria 个体、无约束棒状鼠伤寒沙门菌的运动各向异性

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-09-06 DOI: 10.1021/acsnanoscienceau.6c00080

Kevin Diestelhorst, Fereshteh Ghazisaeedi, Anton Klimek, Sebastian Braetz, Karsten Tedin, Roland R. Netz, Marcus Fulde, Stephan Block

{"title":"Motion Anisotropy of Individual, Unconfined Rod-Like-Shaped Salmonella Typhimurium Bacteria","authors":"Kevin Diestelhorst, Fereshteh Ghazisaeedi, Anton Klimek, Sebastian Braetz, Karsten Tedin, Roland R. Netz, Marcus Fulde, Stephan Block","doi":"10.1021/acsnanoscienceau.6c00080","DOIUrl":"https://doi.org/10.1021/acsnanoscienceau.6c00080","url":null,"abstract":"With the continuous advancement of microscopic imagingtechniques,the motion of micro- and nanosized particles can be followed withincreasing spatial and temporal accuracy. Analyzing the tracks ofsingle particles enables one to address a broad range of scientificquestions, e.g., the dynamics of active and passive (thermally driven)motion or the transport of particles in complex environments. Whileanisotropic motion, which is exhibited by the vast majority of biologicallyrelevant particles (e.g., bacteria and viruses), has been amply studiedin theoretical works, only little experimental data with single-particleresolution have been reported so far. In this study, fluorescencemicroscopy is used to follow the unconstrained motion of green-fluorescentprotein (GFP)-labeled Salmonella enterica serovar Typhimurium (S. Typhimurium) in bulk. Bydecomposing the motion of individual bacteria into contributions paralleland perpendicular to the bacterial long axis, we introduce new scoresthat quantify the degree of motile activity and alignment with highthroughput. We find that S. Typhimurium possessesa surprisingly broad spectrum of opening angles that range from fullalignment of the bacterial long axis with the direction of translationalmotion to no alignment at all. Applied to mutants, in which motility-relatedproteins (the flagellins FljB and FliC) have been deleted, we findthat wild-type (WT) and FliC-expressing S. Typhimuriumexhibit very similar motility but differ significantly in the fractionof actively moving bacteria.","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"6 5","pages":"913–922"},"PeriodicalIF":7.5,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atomic-Scale Anisotropy Competition Drives Spin Reorientation in Intercalated 2D Ferromagnets 原子尺度的各向异性竞争驱动嵌入二维铁磁体的自旋取向

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-07-07 DOI: 10.1021/acsnanoscienceau.6c00043

Yu-Sheng Tseng, Wan-Sheng Tang, Bao-Huei Huang, Yu-Hui Tang

{"title":"Atomic-Scale Anisotropy Competition Drives Spin Reorientation in Intercalated 2D Ferromagnets","authors":"Yu-Sheng Tseng, Wan-Sheng Tang, Bao-Huei Huang, Yu-Hui Tang","doi":"10.1021/acsnanoscienceau.6c00043","DOIUrl":"https://doi.org/10.1021/acsnanoscienceau.6c00043","url":null,"abstract":"Precise control overmagnetic anisotropy (MA) in two-dimensional(2D) van der Waals ferromagnets is essential for advancing next-generationspintronics; however, the atomic-scale mechanisms dictating intercalation-inducedMA modulation remain largely unresolved. In this study, we elucidatethe microscopic origins of the complex magnetic phase diagram in Cr-intercalatedCrTe2 by integrating layer-resolved density functionaltheory-based spin–orbit torque (DFT-SOT) calculations withmicromagnetic simulations. We uncover a concealed source of perpendicularmagnetic anisotropy (PMA) localized within the intercalation layer,which directly competes with the robust surface-driven in-plane magneticanisotropy (IMA). Macroscopically, this atomic-scale competition drivesa thickness-dependent spin reorientation transition, wherein the volumetricaccumulation of bulk-like PMA ultimately dominates over interfacialeffects. Our findings propose a plausible microscopic framework forunderstanding the stoichiometry-dependent anisotropy in chromium chalcogenides,offering a promising theoretical perspective for exploring magneticphases in 2D spintronic architectures.","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"6 5","pages":"850–856"},"PeriodicalIF":7.5,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Interstitial Nonmetal Doping of Palladium-Based Catalysts for Alkyne Semihydrogenation 炔半加氢钯基催化剂的间隙掺杂研究

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-09-08 DOI: 10.1021/acsnanoscienceau.6c00134

Ruiyun Guo, Yuan Ren, Qixiao Han, Yanjin Wei, Jinyuan Zhang, Can Tang, Yibin Liu, Xiaobo Duan, Anyu Feng, Mingshang Jin

{"title":"Interstitial Nonmetal Doping of Palladium-Based Catalysts for Alkyne Semihydrogenation","authors":"Ruiyun Guo, Yuan Ren, Qixiao Han, Yanjin Wei, Jinyuan Zhang, Can Tang, Yibin Liu, Xiaobo Duan, Anyu Feng, Mingshang Jin","doi":"10.1021/acsnanoscienceau.6c00134","DOIUrl":"https://doi.org/10.1021/acsnanoscienceau.6c00134","url":null,"abstract":"Selective hydrogenation of alkynes over Pd-based catalystsis acore industrial process for purifying crude alkenes from steam crackingand synthesizing high-value-added fine alkene chemicals. Despite extensiveresearch efforts, achieving simultaneous improvement in alkene selectivityand catalytic activity remains a long-standing challenge, as traditionalPd site modulation strategies are inherently limited by the scalingrelationships between alkyne and alkene adsorption energies. In recentyears, interstitial nonmetal (e.g., B, C, N, P, S)doping has emerged as a promising modulation strategy to simultaneouslyboost alkyne conversion and alkene selectivity in Pd catalysis. Thesynergistic electronic and geometric effects induced by interstitialnonmetal atoms modulate the adsorption affinity of reactants and products,enabling Pd to preferentially adsorb alkynes, while simultaneouslyisolating active Pd ensembles or suppressing subsurface hydrogen formation,thereby enhancing the overall catalytic performance. In this review,we provide the first systematic overview of recent advances in interstitialnonmetal-doped Pd catalysts for selective alkyne hydrogenation, withan elaboration of their intrinsic modulation mechanisms. We beginby clarifying the fundamental mechanisms of Pd-catalyzed alkyne semihydrogenation,the limitations of traditional modification strategies, and the uniquemerits of interstitial nonmetal doping. Then, we highlight the catalyticperformance and underlying modulation mechanisms of different interstitialnonmetal dopants for improving the selectivity of Pd catalysts inboth thermocatalytic and electrocatalytic alkyne semihydrogenation.Finally, we outline the existing challenges and future perspectivesfor the development of high-performance interstitial nonmetal-dopedPd-based catalysts toward alkyne semihydrogenation.","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"6 5","pages":"795–820"},"PeriodicalIF":7.5,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-Index-Faceted Cu Nanoparticles in Ag–Cu Tandem Catalysts for Selective CO2 Electroreduction 高指数面铜纳米颗粒在Ag-Cu串联催化剂中的选择性CO2电还原

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-09-07 DOI: 10.1021/acsnanoscienceau.6c00129

Guangtao Wang, Simin Li, Chao Yu, Yang Zhou, Wenlei Zhu, Bo Shen

{"title":"High-Index-Faceted Cu Nanoparticles in Ag–Cu Tandem Catalysts for Selective CO2 Electroreduction","authors":"Guangtao Wang, Simin Li, Chao Yu, Yang Zhou, Wenlei Zhu, Bo Shen","doi":"10.1021/acsnanoscienceau.6c00129","DOIUrl":"https://doi.org/10.1021/acsnanoscienceau.6c00129","url":null,"abstract":"Facet engineeringof Cu-based nanocatalysts is a promisingstrategyfor regulating the selectivity of CO2 and CO electroreductionbecause surface atomic arrangements strongly influence intermediateadsorption and reaction pathways. Compared with low-index facets,high-index facets contain abundant steps, kinks, and low-coordinatedatoms, providing diverse active ensembles that can facilitate CO adsorptionand subsequent C–C coupling. However, the catalytic roles ofhigh-index-faceted Cu nanocatalysts remain largely unexplored. Herein,tetrahexahedral (THH) and hexoctahedral (HOH) high-index-faceted Cunanoparticles were integrated with a porous Ag foam to construct Cu/Agtandem catalysts for CO2 electroreduction. The C2+ selectivity follows the order HOH Cu/Ag > THH Cu/Ag> non-facet-controlled Cu/Ag, with HOH Cu/Ag achieving the highestethylene Faradaic efficiency of 60.37%. In situ spectroscopic measurementsusing HOH Cu/Ag as a representative high-index-faceted catalyst indicatethe formation of abundant adsorbed CO and possible CO-derived couplingintermediates within the potential range associated with pronouncedethylene production. Stability measurements further show that themorphology and catalytic selectivity are largely retained under moderateoperating conditions, whereas more negative potentials induce surfaceroughening and gradual performance decay. This work provides a platformfor investigating morphology-dependent selectivity in high-index-facetedCu catalysts during CO2 electroreduction.","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"6 5","pages":"1029–1036"},"PeriodicalIF":7.5,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydrophilicity as Compensation of Hydrogen-Bond Defects at Graphene Oxide Interfaces 亲水性对氧化石墨烯界面氢键缺陷的补偿

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-07-20 DOI: 10.1021/acsnanoscienceau.6c00063

Patrick R. B. Côrtes, Nicolás A. Loubet, Mateus H. Köhler, José Rafael Bordin, Gustavo A. Appignanesi

{"title":"Hydrophilicity as Compensation of Hydrogen-Bond Defects at Graphene Oxide Interfaces","authors":"Patrick R. B. Côrtes, Nicolás A. Loubet, Mateus H. Köhler, José Rafael Bordin, Gustavo A. Appignanesi","doi":"10.1021/acsnanoscienceau.6c00063","DOIUrl":"https://doi.org/10.1021/acsnanoscienceau.6c00063","url":null,"abstract":"Hydrophilicity iswell-defined macroscopically, yet itsmolecularorigin remains elusive. Here, molecular dynamics simulations combinedwith the V4S structural index are used to resolve hydrophilicityat the molecular-site level and quantify the spatial extent of hydrationperturbations induced by oxygen functional groups at graphene oxideinterfaces. We show that epoxy and hydroxyl groups induce distincthydration regimes: hydroxyl groups form strong hydrogen bonds andstabilize the interfacial network over larger spatial ranges, whereasepoxy groups promote weaker, distorted interactions that disrupt localconnectivity. This contrast demonstrates that chemically similar functionalitiescan generate qualitatively different interfacial responses, highlightingthe central role of nanoscale heterogeneity. Within this framework,hydrophobicity emerges as the inability of a surface to compensatefor hydrogen-bond defects in its hydration layer, providing a microscopicbasis for wettability and guiding the design of carbon-based nanomaterials.","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"6 5","pages":"885–894"},"PeriodicalIF":7.5,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149233297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

QMini: A Portable Device for Infectious Disease Testing QMini：便携式传染病检测设备

IF 7.5

ACS Nanoscience Au Pub Date : 2026-10-21 Epub Date: 2026-10-05 DOI: 10.1021/acsnanoscienceau.6c00109

Nafisa Mahbub, Matthew Osborne, Hongmin Chen, Ayokunle Lekuti, Warren C. W. Chan

引用次数: 0