ACS Nanoscience AuPub Date : 2024-02-29DOI: 10.1021/acsnanoscienceau.3c00057
Emma J. Endres, Jeremy R. Bairan Espano, Alexandra Koziel, Antony R. Peng, Andrey A. Shults and Janet E. Macdonald*,
{"title":"Controlling Phase in Colloidal Synthesis","authors":"Emma J. Endres, Jeremy R. Bairan Espano, Alexandra Koziel, Antony R. Peng, Andrey A. Shults and Janet E. Macdonald*, ","doi":"10.1021/acsnanoscienceau.3c00057","DOIUrl":"10.1021/acsnanoscienceau.3c00057","url":null,"abstract":"<p >A fundamental precept of chemistry is that properties are manifestations of the elements present and their arrangement in space. Controlling the arrangement of atoms in nanocrystals is not well understood in nanocrystal synthesis, especially in the transition metal chalcogenides and pnictides, which have rich phase spaces. This Perspective will cover some of the recent advances and current challenges. The perspective includes introductions to challenges particular to chalcogenide and pnictide chemistry, the often-convoluted roles of bond dissociation energies and mechanisms by which precursors break down, using very organized methods to map the synthetic phase space, a discussion of polytype control, and challenges in characterization, especially for solving novel structures on the nanoscale and time-resolved studies.</p>","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"4 3","pages":"158–175"},"PeriodicalIF":0.0,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsnanoscienceau.3c00057","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140003833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS Nanoscience AuPub Date : 2024-02-21DOI: 10.1021/acsnanoscienceau.4c00004
Raymond E. Schaak*,
{"title":"ACS Nanoscience Au in 2024: Looking Back and Gazing Forward","authors":"Raymond E. Schaak*, ","doi":"10.1021/acsnanoscienceau.4c00004","DOIUrl":"https://doi.org/10.1021/acsnanoscienceau.4c00004","url":null,"abstract":"","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"4 1","pages":"1–2"},"PeriodicalIF":0.0,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsnanoscienceau.4c00004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139914433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS Nanoscience AuPub Date : 2024-02-14DOI: 10.1021/acsnanoscienceau.3c00055
Maxwell G. Tetrick, and , Catherine J. Murphy*,
{"title":"Leveraging Tunable Nanoparticle Surface Functionalization to Alter Cellular Migration","authors":"Maxwell G. Tetrick, and , Catherine J. Murphy*, ","doi":"10.1021/acsnanoscienceau.3c00055","DOIUrl":"10.1021/acsnanoscienceau.3c00055","url":null,"abstract":"<p >Gold nanoparticles (AuNPs) are a promising platform for biomedical applications including therapeutics, imaging, and drug delivery. While much of the literature surrounding the introduction of AuNPs into cellular systems focuses on uptake and cytotoxicity, less is understood about how AuNPs can indirectly affect cells via interactions with the extracellular environment. Previous work has shown that the monocytic cell line THP-1’s ability to undergo chemotaxis in response to a gradient of monocyte chemoattractant protein 1 (MCP-1) was compromised by extracellular polysulfonated AuNPs, presumably by binding to MCP-1 with some preference over other proteins in the media. The hypothesis to be explored in this work is that the degree of sulfonation of the surface would therefore be correlated with the ability of AuNPs to interrupt chemotaxis. Highly sulfonated poly(styrenesulfonate)-coated AuNPs caused strong inhibition of THP-1 chemotaxis; by reducing the degree of sulfonation on the AuNP surface with copolymers [poly(styrenesulfonate-<i>co</i>-maleate) of different compositions], it was found that medium and low sulfonation levels caused weak to no inhibition, respectively. Small, rigid molecular sulfonate surfaces were relatively ineffective at chemotaxis inhibition. Unusually, free poly(styrenesulfonate) caused a dose-dependent reversal of THP-1 cell migration: at low concentrations, free poly(styrenesulfonate) significantly inhibited MCP-1-induced chemotaxis. However, at high concentrations, free poly(styrenesulfonate) acted as a chemorepellent, causing a reversal in the cell migration direction.</p>","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"4 3","pages":"205–215"},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsnanoscienceau.3c00055","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139769384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS Nanoscience AuPub Date : 2024-02-13DOI: 10.1021/acsnanoscienceau.3c00059
Edwin J. Miller, Kameron R. Hansen and Luisa Whittaker-Brooks*,
{"title":"Charge Transport and Ion Kinetics in 1D TiS2 Structures are Dependent on the Introduction of Selenium Extrinsic Atoms","authors":"Edwin J. Miller, Kameron R. Hansen and Luisa Whittaker-Brooks*, ","doi":"10.1021/acsnanoscienceau.3c00059","DOIUrl":"10.1021/acsnanoscienceau.3c00059","url":null,"abstract":"<p >Improving charge insertion into intercalation hosts is essential for crucial energy and memory technologies. The layered material TiS<sub>2</sub> provides a promising template for study, but further development of this compound demands improvement to its ion kinetics. Here, we report the incorporation of Se atoms into TiS<sub>2</sub> nanobelts to address barriers related to sluggish ion motion in the material. TiS<sub>1.8</sub>Se<sub>0.2</sub> nanobelts are synthesized through a solid-state method, and structural and electrochemical characterizations reveal that solid solutions based on TiS<sub>1.8</sub>Se<sub>0.2</sub> nanobelts display increased interlayer spacing and electrical conductivity compared to pure TiS<sub>2</sub> nanobelts. Cyclic voltammetry and electrochemical impedance spectroscopy indicate that the capacitive behavior of the TiS<sub>2</sub> electrode is improved upon Se incorporation, particularly at low depths of discharge in the materials. The presence of Se in the structure can be directly related to an increased pseudocapacitive contribution to electrode behavior at a low Li<sup>+</sup> content in the material and thus to improved ion kinetics in the TiS<sub>1.8</sub>Se<sub>0.2</sub> nanobelts.</p>","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"4 2","pages":"146–157"},"PeriodicalIF":0.0,"publicationDate":"2024-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsnanoscienceau.3c00059","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139769383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS Nanoscience AuPub Date : 2024-01-30DOI: 10.1021/acsnanoscienceau.3c00047
Chengye Dong, Li-Syuan Lu, Yu-Chuan Lin* and Joshua A. Robinson*,
{"title":"Air-Stable, Large-Area 2D Metals and Semiconductors","authors":"Chengye Dong, Li-Syuan Lu, Yu-Chuan Lin* and Joshua A. Robinson*, ","doi":"10.1021/acsnanoscienceau.3c00047","DOIUrl":"10.1021/acsnanoscienceau.3c00047","url":null,"abstract":"<p >Two-dimensional (2D) materials are popular for fundamental physics study and technological applications in next-generation electronics, spintronics, and optoelectronic devices due to a wide range of intriguing physical and chemical properties. Recently, the family of 2D metals and 2D semiconductors has been expanding rapidly because they offer properties once unknown to us. One of the challenges to fully access their properties is poor stability in ambient conditions. In the first half of this Review, we briefly summarize common methods of preparing 2D metals and highlight some recent approaches for making air-stable 2D metals. Additionally, we introduce the physicochemical properties of some air-stable 2D metals recently explored. The second half discusses the air stability and oxidation mechanisms of 2D transition metal dichalcogenides and some elemental 2D semiconductors. Their air stability can be enhanced by optimizing growth temperature, substrates, and precursors during 2D material growth to improve material quality, which will be discussed. Other methods, including doping, postgrowth annealing, and encapsulation of insulators that can suppress defects and isolate the encapsulated samples from the ambient environment, will be reviewed.</p>","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"4 2","pages":"115–127"},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsnanoscienceau.3c00047","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139649617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS Nanoscience AuPub Date : 2023-12-23DOI: 10.1021/acsnanoscienceau.3c00041
Darina Francesca Picchi, Catalina Biglione and Patricia Horcajada*,
{"title":"Nanocomposites Based on Magnetic Nanoparticles and Metal–Organic Frameworks for Therapy, Diagnosis, and Theragnostics","authors":"Darina Francesca Picchi, Catalina Biglione and Patricia Horcajada*, ","doi":"10.1021/acsnanoscienceau.3c00041","DOIUrl":"10.1021/acsnanoscienceau.3c00041","url":null,"abstract":"<p >In the last two decades, metal–organic frameworks (MOFs) with highly tunable structure and porosity, have emerged as drug nanocarriers in the biomedical field. In particular, nanoscaled MOFs (nanoMOFs) have been widely investigated because of their potential biocompatibility, high drug loadings, and progressive release. To enhance their properties, MOFs have been combined with magnetic nanoparticles (MNPs) to form magnetic nanocomposites (MNP@MOF) with additional functionalities. Due to the magnetic properties of the MNPs, their presence in the nanosystems enables potential combinatorial magnetic targeted therapy and diagnosis. In this Review, we analyze the four main synthetic strategies currently employed for the fabrication of MNP@MOF nanocomposites, namely, mixing, <i>in situ</i> formation of MNPs in presynthesized MOF, <i>in situ</i> formation of MOFs in the presence of MNPs, and layer-by-layer methods. Additionally, we discuss the current progress in bioapplications, focusing on drug delivery systems (DDSs), magnetic resonance imaging (MRI), magnetic hyperthermia (MHT), and theragnostic systems. Overall, we provide a comprehensive overview of the recent advances in the development and bioapplications of MNP@MOF nanocomposites, highlighting their potential for future biomedical applications with a critical analysis of the challenges and limitations of these nanocomposites in terms of their synthesis, characterization, biocompatibility, and applicability.</p>","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"4 2","pages":"85–114"},"PeriodicalIF":0.0,"publicationDate":"2023-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsnanoscienceau.3c00041","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139030374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS Nanoscience AuPub Date : 2023-12-22DOI: 10.1021/acsnanoscienceau.3c00062
Amogh Kinikar, Xiao-Ye Wang, Marco Di Giovannantonio, José I. Urgel, Pengcai Liu, Kristjan Eimre, Carlo A. Pignedoli*, Samuel Stolz, Max Bommert, Shantanu Mishra, Qiang Sun, Roland Widmer, Zijie Qiu, Akimitsu Narita, Klaus Müllen*, Pascal Ruffieux and Roman Fasel*,
{"title":"Sterically Selective [3 + 3] Cycloaromatization in the On-Surface Synthesis of Nanographenes","authors":"Amogh Kinikar, Xiao-Ye Wang, Marco Di Giovannantonio, José I. Urgel, Pengcai Liu, Kristjan Eimre, Carlo A. Pignedoli*, Samuel Stolz, Max Bommert, Shantanu Mishra, Qiang Sun, Roland Widmer, Zijie Qiu, Akimitsu Narita, Klaus Müllen*, Pascal Ruffieux and Roman Fasel*, ","doi":"10.1021/acsnanoscienceau.3c00062","DOIUrl":"10.1021/acsnanoscienceau.3c00062","url":null,"abstract":"<p >Surface-catalyzed reactions have been used to synthesize carbon nanomaterials with atomically predefined structures. The recent discovery of a gold surface-catalyzed [3 + 3] cycloaromatization of isopropyl substituted arenes has enabled the on-surface synthesis of arylene-phenylene copolymers, where the surface activates the isopropyl substituents to form phenylene rings by intermolecular coupling. However, the resulting polymers suffered from undesired cross-linking when more than two molecules reacted at a single site. Here we show that such cross-links can be prevented through steric protection by attaching the isopropyl groups to larger arene cores. Upon thermal activation of isopropyl-substituted 8,9-dioxa-8a-borabenzo[<i>fg</i>]tetracene on Au(111), cycloaromatization is observed to occur exclusively between the two molecules. The cycloaromatization intermediate formed by the covalent linking of two molecules is prevented from reacting with further molecules by the wide benzotetracene core, resulting in highly selective one-to-one coupling. Our findings extend the versatility of the [3 + 3] cycloaromatization of isopropyl substituents and point toward steric protection as a powerful concept for suppressing competing reaction pathways in on-surface synthesis.</p>","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"4 2","pages":"128–135"},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsnanoscienceau.3c00062","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138946698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS Nanoscience AuPub Date : 2023-12-01DOI: 10.1021/acsnanoscienceau.3c00051
Benjamin Harrington, Ziyang Ye, Laura Signor and Andrea D. Pickel*,
{"title":"Luminescence Thermometry Beyond the Biological Realm","authors":"Benjamin Harrington, Ziyang Ye, Laura Signor and Andrea D. Pickel*, ","doi":"10.1021/acsnanoscienceau.3c00051","DOIUrl":"10.1021/acsnanoscienceau.3c00051","url":null,"abstract":"<p >As the field of luminescence thermometry has matured, practical applications of luminescence thermometry techniques have grown in both frequency and scope. Due to the biocompatibility of most luminescent thermometers, many of these applications fall within the realm of biology. However, luminescence thermometry is increasingly employed beyond the biological realm, with expanding applications in areas such as thermal characterization of microelectronics, catalysis, and plasmonics. Here, we review the motivations, methodologies, and advances linked to nonbiological applications of luminescence thermometry. We begin with a brief overview of luminescence thermometry probes and techniques, focusing on those most commonly used for nonbiological applications. We then address measurement capabilities that are particularly relevant for these applications and provide a detailed survey of results across various application categories. Throughout the review, we highlight measurement challenges and requirements that are distinct from those of biological applications. Finally, we discuss emerging areas and future directions that present opportunities for continued research.</p>","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"4 1","pages":"30–61"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsnanoscienceau.3c00051","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138537596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS Nanoscience AuPub Date : 2023-11-22DOI: 10.1021/acsnanoscienceau.3c00031
Cyrus Koroni*, Kiev Dixon, Pete Barnes, Dewen Hou, Luke Landsberg, Zihongbo Wang, Galib Grbic’, Sarah Pooley, Sam Frisone, Tristan Olsen, Allison Muenzer, Dustin Nguyen, Blayze Bernal and Hui Xiong*,
{"title":"Morphology and Crystallinity Effects of Nanochanneled Niobium Oxide Electrodes for Na-Ion Batteries","authors":"Cyrus Koroni*, Kiev Dixon, Pete Barnes, Dewen Hou, Luke Landsberg, Zihongbo Wang, Galib Grbic’, Sarah Pooley, Sam Frisone, Tristan Olsen, Allison Muenzer, Dustin Nguyen, Blayze Bernal and Hui Xiong*, ","doi":"10.1021/acsnanoscienceau.3c00031","DOIUrl":"10.1021/acsnanoscienceau.3c00031","url":null,"abstract":"<p >Niobium pentoxide (Nb<sub>2</sub>O<sub>5</sub>) is a promising negative electrode for sodium ion batteries (SIBs). By engineering the morphology and crystallinity of nanochanneled niobium oxides (NCNOs), the kinetic behavior and charge storage mechanism of Nb<sub>2</sub>O<sub>5</sub> electrodes were investigated. Amorphous and crystalline NCNO samples were made by modulating anodization conditions (20–40 V and 140–180 °C) to synthesize nanostructures of varying pore sizes and wall thicknesses with identical chemical composition. The electrochemical energy storage properties of the NCNOs were studied, with the amorphous samples showing better overall rate performance than the crystalline samples. The enhanced rate performance of the amorphous samples is attributed to the higher capacitive contributions and Na-ion diffusivity analyzed from cyclic voltammetry (CV) and the galvanostatic intermittent titration technique (GITT). It was found that the amorphous samples with smaller wall thicknesses facilitated improved kinetics. Among samples with similar pore size and wall thickness, the difference in their power performance stems from the crystallinity effect, which plays a more significant role in the resulting kinetics of the materials for Na-ion batteries.</p>","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"4 1","pages":"76–84"},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsnanoscienceau.3c00031","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138537632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS Nanoscience AuPub Date : 2023-11-19DOI: 10.1021/acsnanoscienceau.3c00045
Matthew Peters, Declan McIntosh, Alexandra Branzan Albu, Cuifeng Ying and Reuven Gordon*,
{"title":"Label-Free Tracking of Proteins through Plasmon-Enhanced Interference","authors":"Matthew Peters, Declan McIntosh, Alexandra Branzan Albu, Cuifeng Ying and Reuven Gordon*, ","doi":"10.1021/acsnanoscienceau.3c00045","DOIUrl":"10.1021/acsnanoscienceau.3c00045","url":null,"abstract":"<p >Single unmodified biomolecules in solution can be observed and characterized by interferometric imaging approaches; however, Rayleigh scattering limits this to larger proteins (typically >30 kDa). We observe real-time image tracking of unmodified proteins down to 14 kDa using interference imaging enhanced by surface plasmons launched at an aperture in a metal film. The larger proteins show slower diffusion, quantified by tracking. When the diffusing protein is finally trapped by the nanoaperture, we perform complementary power spectral density and noise amplitude analysis, which gives information about the protein. This approach allows for rapid protein characterization with minimal sample preparation and opens the door to characterizing protein interactions in real time.</p>","PeriodicalId":29799,"journal":{"name":"ACS Nanoscience Au","volume":"4 1","pages":"69–75"},"PeriodicalIF":0.0,"publicationDate":"2023-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/acsnanoscienceau.3c00045","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138537597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}