ACS Physical Chemistry AuPub Date : 2026-07-22Epub Date: 2026-04-07DOI: 10.1021/acsphyschemau.6c00006
Sebok Lee, Taehyung Jang, Jongwon Im, Yoonsoo Pang
{"title":"Ultrafast Charge Transfer Dynamics of Thioflavin T Probed by Time-Resolved Raman Spectroscopy","authors":"Sebok Lee, Taehyung Jang, Jongwon Im, Yoonsoo Pang","doi":"10.1021/acsphyschemau.6c00006","DOIUrl":"10.1021/acsphyschemau.6c00006","url":null,"abstract":"<p>Thioflavin T (ThT)is a commonly used dye that probes amyloid fibrilsassociated with Alzheimer’s and Parkinson’s diseases.Binding to amyloid fibrils significantly enhances ThT fluorescence,while hindering the formation of the twisted intramolecular chargetransfer (ICT) state in the dimethylaniline group. On the other hand,ThT fluorescence is strongly quenched in aqueous and aliphatic alcoholsolutions with efficient ICT in the excited states. No direct experimentalevidence for the structural changes of ThT with ICT has been reportedyet. In this work, we report the structural changes of ThT duringICT by time-resolved Raman spectroscopic methods, which include thebend of the benzothiazole and the twist of the dimethylaniline group.Both femtosecond stimulated Raman spectroscopy and impulsive stimulatedRaman spectroscopy suggest that the ICT coordinate of ThT can be stronglycoupled with the low-frequency deformation modes. Time-dependent densityfunctional theory calculations and the evaluated vibrational reorganizationenergies between the ground and excited states strongly support ourexperimental results based on time-resolved vibrational spectroscopy.</p>","PeriodicalId":29796,"journal":{"name":"ACS Physical Chemistry Au","volume":"6 4","pages":"678–686"},"PeriodicalIF":4.8,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biomass-Derived Red–Blue Solvatochromic Carbon Quantum Dots for UV-Blocking and Active Packaging Applications","authors":"Tanachporn Lukprang, Pakorn Preechaburana, Supaluck Amloy","doi":"10.1021/acsphyschemau.6c00013","DOIUrl":"10.1021/acsphyschemau.6c00013","url":null,"abstract":"<p>In this research, biomass-derived carbon quantum dots(CQDs) withsolvent-dependent emission colors were synthesized from mangosteenleaves via a solvent-mediated hydrothermal route, in order to elucidatethe relationship between structure and emission and to evaluate theirpotential for multifunctional packaging applications. Systematic morphologicaland structural analyses demonstrated that the solvent polarity governedthe degree of carbonization, particle size, and surface chemistry.Red-emissive CQDs (R-CQDs) were formed in a less polar medium andexhibited larger sp<sup>2</sup> domains enriched with hydroxyl groups,whereas blue-emissive CQDs (B-CQDs) synthesized in a polar solventhad smaller sp<sup>2</sup> domains with higher values for the contentof oxygen- and nitrogen-containing functionalities. These distinctionsresulted in excitation-independent red emission for R-CQDs and excitation-tunableblue-green emission for B-CQDs. R-CQDs showed enhanced antioxidantactivity (IC<sub>50</sub> = 8.84 μg mL<sup>–1</sup>)relative to B-CQDs (IC<sub>50</sub> = 21.03 μg mL<sup>–1</sup>), while antibacterial activity against <em>Escherichia coli</em> and <em>Staphylococcus aureus</em> was observed exclusively for R-CQDs, indicating a structure-dependentantibacterial response. When the CQDs were incorporated into poly(vinylalcohol) (PVA) matrices, the nanocomposite films demonstrated enhancedUV-blocking performance, with R-CQD/PVA film giving stronger attenuationdue to enhanced π–π* transitions and more efficientinterfacial energy transfer. Storage tests also showed that when tomatoeswere packaged with R-CQD/PVA film, ripening was delayed by approximately7–14 days compared to the control films. These findings establishclear correlations between solvent, structure, and function for biomass-derivedCQDs and suggest a sustainable strategy for designing multifunctionalnanocomposite films for UV-protective and active food-packaging applications.</p>","PeriodicalId":29796,"journal":{"name":"ACS Physical Chemistry Au","volume":"6 4","pages":"739–753"},"PeriodicalIF":4.8,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS Physical Chemistry AuPub Date : 2026-07-22Epub Date: 2026-05-13DOI: 10.1021/acsphyschemau.6c00007
Johannes Fiedler
{"title":"Environment-Induced Renormalization of Molecular Polarizabilities","authors":"Johannes Fiedler","doi":"10.1021/acsphyschemau.6c00007","DOIUrl":"10.1021/acsphyschemau.6c00007","url":null,"abstract":"<p>The electromagneticenvironment modifies atomic properties throughself-energy corrections arising from vacuum-field fluctuations shapedby material boundaries. While such effects are commonly discussedin terms of energy level shifts and decay rates, their influence onatomic response functions has received much less attention. Here,we investigate how environment-induced self-energy corrections renormalizethe dynamic polarizability of an atom. Using macroscopic quantum electrodynamics,we analyze a hydrogen atom at the center of a spherical vacuum cavityembedded in a dielectric medium. The cavity-induced Lamb shifts ofthe atomic levels propagate into the frequency-dependent polarizabilitythrough the sum-over-states representation. We find that cavity confinementshifts absorptive resonances, modifies their amplitudes, and can generateadditional geometry-induced spectral features within the finite rangeof cavity radii. The polarizability along the imaginary-frequencyaxis remains well-behaved, consistent with a passive electromagneticenvironment. These results demonstrate that structured electromagneticenvironments can qualitatively reshape atomic response functions andprovide a route toward geometry-aware descriptions of molecular polarizabilitiesin complex media.</p>","PeriodicalId":29796,"journal":{"name":"ACS Physical Chemistry Au","volume":"6 4","pages":"687–698"},"PeriodicalIF":4.8,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS Physical Chemistry AuPub Date : 2026-07-22Epub Date: 2026-06-04DOI: 10.1021/acsphyschemau.6c00050
Carl G. Henning Hansen, Simone Orioli, Kresten Lindorff-Larsen
{"title":"A Bayesian Approach to Interpret Time-Resolved Experiments Using Molecular Simulations","authors":"Carl G. Henning Hansen, Simone Orioli, Kresten Lindorff-Larsen","doi":"10.1021/acsphyschemau.6c00050","DOIUrl":"10.1021/acsphyschemau.6c00050","url":null,"abstract":"<p>Time-resolved experimentscan provide unique insightsinto dynamicprocesses such as protein folding, ligand binding, and many othermolecular processes. These experiments are, however, difficult tointerpret at the molecular level because they generally report onsignals that are averaged over multiple configurational states andbecause they often report on processes that are well beyond what canbe studied using most simulation methods. Here, we describe an approachto use molecular simulations to model and interpret time-resolvedexperiments. The method, which we term trBME (time-resolved Bayesian/maximumentropy), is based on combining a model for the dynamics of the systemwith three-dimensional structural models of the protein that can becompared to the experiments. We illustrate the utility of the modelusing synthetic time-resolved small-angle X-ray scattering data andshow how it can be used to extract detailed information from the experimentalmeasurements about the process of protein unfolding.</p>","PeriodicalId":29796,"journal":{"name":"ACS Physical Chemistry Au","volume":"6 4","pages":"878–886"},"PeriodicalIF":4.8,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS Physical Chemistry AuPub Date : 2026-07-22Epub Date: 2026-05-14DOI: 10.1021/acsphyschemau.6c00017
Agnieszka Siomra, Dominika Wawrzynczyk, Marcin Nyk
{"title":"Nonlinear Optical Properties of Molybdenum Disulfide Nanocrystals for Luminescence-Based Sensor Applications","authors":"Agnieszka Siomra, Dominika Wawrzynczyk, Marcin Nyk","doi":"10.1021/acsphyschemau.6c00017","DOIUrl":"10.1021/acsphyschemau.6c00017","url":null,"abstract":"<p>In this work, the nonlinear optical (NLO) propertiesof ca. 4.6nm molybdenum disulfide nanocrystals (MoS<sub>2</sub> NCs) were examined.The spectrally resolved NLO response of the synthesized NCs was investigatedacross excitation wavelengths ranging from ∼600 to 1000 nm.The maximum σ<sub>2</sub> value of 4.0 × 10<sup>–47</sup> cm<sup>4</sup>·s·photon<sup>–1</sup> per NC wasobtained at an excitation wavelength of 720 nm, indicating efficienttwo-photon absorption and strong NLO activity within the near-infraredregion. Furthermore, the sensing capabilities of the water-dispersedMoS<sub>2</sub> NCs toward ferric ion and temperature variations wereexamined in the two-photon excitation regime. The results revealedthat ion sensing remains comparably efficient under both one- andtwo-photon excitation, whereas temperature sensing in the two-photonregime demonstrates consistent and reliable performance. The findingsprovide insights into the NLO characteristics of colloidal MoS<sub>2</sub> NCs and highlight their potential as multifunctional nanomaterialsfor future advanced optical sensing technologies.</p>","PeriodicalId":29796,"journal":{"name":"ACS Physical Chemistry Au","volume":"6 4","pages":"754–762"},"PeriodicalIF":4.8,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS Physical Chemistry AuPub Date : 2026-07-22Epub Date: 2026-06-09DOI: 10.1021/acsphyschemau.6c00029
Anna Werkovits, Simon B. Hollweger, Oliver T. Hofmann
{"title":"Emergent Rate Laws for Collective Lying–Standing Transitions","authors":"Anna Werkovits, Simon B. Hollweger, Oliver T. Hofmann","doi":"10.1021/acsphyschemau.6c00029","DOIUrl":"10.1021/acsphyschemau.6c00029","url":null,"abstract":"<p>Lying–standingtransitions in the first molecular monolayerat organic–inorganic interfaces strongly influence interfacedipoles, energy-level alignment, and growth modes, yet their collectivekinetics remain difficult to predict. Here, we establish a quantitativeadsorbate-to-kinetics relationship for such transitions using first-principles-basedkinetic Monte Carlo simulations combined with a mean-field-type coarse-grainingstrategy. Focusing on the prototypical system tetracyanoethylene onCu(111), we show that the collective transition rate cannot be inferredfrom any single elementary step but instead emerges from a small setof coupled microscopic processes, including reorientation, adsorption,and diffusion. A local two-step reorientation mechanism captures thediffusion-limited regime, while diffusion of lying molecules acceleratesthe transition in diffusion-enhanced regimes by sterically suppressingback-reorientation via vacancy–molecule decoupling. This effectis captured by a regime-dependent geometric factor that quantitativelyaccounts for deviations between single-molecule and collective rateconstants. By systematically varying molecular size and footprintratio, we demonstrate that geometry provides a powerful intrinsiccontrol parameter. While the collective rate scales approximatelyproportionally with molecular area, increasing the footprint ratiobetween lying and standing configurations leads to order-of-magnitudeaccelerations due to enhanced vacancy creation and diffusion-assistedstabilization. Based on these results, we derive an explicit analyticalexpression for the collective reorientation rate constant that linkstemperature- and pressure-dependent microscopic rate constants togeometric parameters. The resulting formulation quantitatively reproducesthe simulation results across kinetic regimes and provides transferabledesign principles for engineering lying–standing transitiontime scales at organic–inorganic interfaces.</p>","PeriodicalId":29796,"journal":{"name":"ACS Physical Chemistry Au","volume":"6 4","pages":"815–826"},"PeriodicalIF":4.8,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS Physical Chemistry AuPub Date : 2026-07-22Epub Date: 2026-05-29DOI: 10.1021/acsphyschemau.6c00035
João V. P. Valverde, Welisson de P. Silva, Daniel L. Silva, Nícolas O. Decarli, Mieczysław Łapkowski, Leonardo De Boni, Cleber R. Mendonça
{"title":"Multiphoton Absorption in Branched Quadrupolar Diquinoxalines for Two-Photon Polymerization Design","authors":"João V. P. Valverde, Welisson de P. Silva, Daniel L. Silva, Nícolas O. Decarli, Mieczysław Łapkowski, Leonardo De Boni, Cleber R. Mendonça","doi":"10.1021/acsphyschemau.6c00035","DOIUrl":"10.1021/acsphyschemau.6c00035","url":null,"abstract":"<p>We investigated the photophysical properties of threebrancheddiquinoxaline (<strong>DQ</strong>) derivatives and their potential applicationas photoinitiators (PIs) for two-photon polymerization (2PP). Thesecompounds exhibit a quasi-centrosymmetric quadrupolar configuration,functionalized with different electron-donating (ED) moieties. Weperformed detailed linear spectroscopic characterization, as wellas the determination of two- and three-photon absorption cross sections(σ<sub>2<em>PA</em></sub> and σ<sub>3<em>PA</em></sub>), using the spectrally resolved multiphoton-excited fluorescencetechnique. We complemented the study by performing quantum chemicalcalculations at the (TD-)DFT level to obtain relevant informationabout the electronic structure of the compounds and to model theirspectroscopic data. The results showed that the compounds exhibitbroad one-photon absorption in the UV–vis region and fluorescenceemission at <em>ca</em>. 543 nm. Due to their quadrupolarnature, all molecules exhibit significant intramolecular charge transfer.Despite their essentially quadrupolar nature, we observed a symmetry-breakingeffect in the relaxed excited state, conferring a dipolar characterto the molecules. We observed significant σ<sub>2<em>PA</em></sub>, exhibiting the values up to 230 GM, which was attributedto the enhanced structural planarity, facilitating electron delocalizationacross all ED branches and resulting in a more efficient additiveeffect on 2PA response. Additionally, we noted a σ<sub>3<em>PA</em></sub> of approximately 0.02 × 10<sup>−78</sup> cm<sup>6</sup> s<sup>2</sup> photon<sup>–2</sup> at 1100nm. Finally, we confirmed the ability of the <strong>DQ</strong> derivativesto act as two-photon PIs, as demonstrated by the fabrication of 3Dmicrostructures with inherent emissive properties.</p>","PeriodicalId":29796,"journal":{"name":"ACS Physical Chemistry Au","volume":"6 4","pages":"803–814"},"PeriodicalIF":4.8,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS Physical Chemistry AuPub Date : 2026-07-22Epub Date: 2026-05-20DOI: 10.1021/acsphyschemau.6c00038
Rohit Goswami
{"title":"A Tutorial Review of Bayesian Optimization with Gaussian Processes to Accelerate Stationary Point Searches","authors":"Rohit Goswami","doi":"10.1021/acsphyschemau.6c00038","DOIUrl":"10.1021/acsphyschemau.6c00038","url":null,"abstract":"<p>Building local surrogatesto accelerate stationary pointsearcheson potential energy surfaces span decades of effort. Done correctly,surrogates can reduce the number of expensive electronic structureevaluations by factors of several, and in favorable regimes by roughlyan order of magnitude, while preserving the accuracy of the underlyingtheory; the gain depends on oracle cost, search distance, and theavailability of analytical forces. We present a unified Bayesian optimizationview of minimization, single-point saddle searches, and double-endedpath searches: all three share one six-step surrogate loop and differonly in the inner optimization target and the acquisition criterion.The framework uses Gaussian process regression with derivative observations,inverse-distance kernels, and active learning, and we develop optionalextensions for production use, including farthest-point sampling withthe Earth Mover’s Distance, MAP regularization, an adaptivetrust radius, and random Fourier features for scaling. An accompanyingpedagogical Rust code demonstrates that all three applications usethe same Bayesian optimization loop, bridging the gap between theoreticalformulation and practical execution.</p>","PeriodicalId":29796,"journal":{"name":"ACS Physical Chemistry Au","volume":"6 4","pages":"633–664"},"PeriodicalIF":4.8,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lipid Architecture in the Zika Virus","authors":"Camila Assis Tavares, Martín Soñora, Sergio Pantano, Leandro Martínez","doi":"10.1021/acsphyschemau.5c00113","DOIUrl":"10.1021/acsphyschemau.5c00113","url":null,"abstract":"<p>Far from being passive barriers, viral membranes activelyinfluencethe mechanical properties and biological activity of viruses. Theirlipid–protein composition forms a responsive interface thatimpacts how viruses assemble, remain stable, and interact with theirsurroundings. While the behavior of lipids and proteins in cellularmembranes is well-described, their specific contributions within viralsystems remain underexplored, largely due to nanoscale complexityand experimental limitations involved. Here, coarse-grained moleculardynamics simulations of Zika virus were analyzed to characterize lipidorganization inside the virus. Lipid selectivity is strongly influencedby helix residue composition and depth of insertion into the membrane.The amphipathic EH-3 helix, for instance, preferentially coordinateswith POPC but also establishes localized contacts with POPS throughLys and Ser residues, reflecting a balance between hydrophobic andelectrostatic interactions. In contrast, the transmembrane ET-2 helix,dominated by hydrophobic residues, displays reduced lipid selectivity,with only peripheral serines showing a modest preference for POPS.Across the viral envelope, POPE contributes less to residue-specificcoordination, while POPS participates in polar interactions that modulatethe environment near positively charged residues. By shedding lighton how lipids contribute to the architecture of the viral envelopeand membrane, this work offers insights that deepen the understandingof viral particle integrity, guiding target membrane-dependent processesin antiviral design.</p>","PeriodicalId":29796,"journal":{"name":"ACS Physical Chemistry Au","volume":"6 4","pages":"665–677"},"PeriodicalIF":4.8,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ACS Physical Chemistry AuPub Date : 2026-07-22Epub Date: 2026-05-14DOI: 10.1021/acsphyschemau.6c00010
Luis M. G. Abegão, Leonardo R de Almeida, Juliana G. M. Lima, Luciana M. Ramos, Hamilton B. Napolitano, João V. Valverde, Cleber R. Mendonça, Leonardo De Boni, Leandro H. Z. Cocca
{"title":"Coumarin-Based Hybrids: From Linear Photophysical Properties to Multiphoton Excitation Behavior","authors":"Luis M. G. Abegão, Leonardo R de Almeida, Juliana G. M. Lima, Luciana M. Ramos, Hamilton B. Napolitano, João V. Valverde, Cleber R. Mendonça, Leonardo De Boni, Leandro H. Z. Cocca","doi":"10.1021/acsphyschemau.6c00010","DOIUrl":"10.1021/acsphyschemau.6c00010","url":null,"abstract":"<p>Coumarin-based derivatives are recognized as tunablephotonic buildingblocks due to their strong light–matter interaction and relevancefor both linear and nonlinear optical applications. This work presentsan investigation of the linear optical properties and multiphotonexcitation response of four derivatives coupled with benzothiazoleand benzimidazole moieties. The compounds 7-diethylamino-coumarin-benzothiazole,6-bromo-coumarin-benzothiazole, and 7-diethylamino-coumarin-benzimidazoleexhibit nearly identical absorption maxima (∼423–428nm) and emission peaks (∼485 nm), while displaying pronounceddifferences in molar absorptivity and ground to first excited-statetransition dipole moment (μ<sub>01</sub>). The 7-diethylamino-substitutedderivatives show enhanced molar absorptivity (∼5.3 × 10<sup>4</sup> L mol<sup>–1</sup> cm<sup>–1</sup>) and largertransition dipole moment (μ<sub>01</sub> ∼ 8.1 D) comparedto the bromo-substituted (μ<sub>01</sub> ∼ 5.5 D). Incontrast, 7-hydroxyl-coumarin-methyl-benzimidazole exhibits a distinctspectral signature characterized by a larger Stokes shift and lowermolar absorptivity, with an intermediate μ<sub>01</sub> ∼7.0 D reflecting a different electronic balance within the conjugatedframework. Multiphoton excitation experiments using femtosecond laserpulses demonstrate efficient two-photon (800 nm) and three-photon(1200 nm) excited fluorescence for all derivatives. Remarkably, thehydroxylated derivative combines an exceptionally high fluorescencequantum yield (∼48%) with a measurable excited-state lifetime(∼3 ns), identifying it as the most promising candidate forbright photoluminescent probing under one-, two-, and three-photonexcitation.</p>","PeriodicalId":29796,"journal":{"name":"ACS Physical Chemistry Au","volume":"6 4","pages":"726–738"},"PeriodicalIF":4.8,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}