Environment & Health最新文献

{"title":"","authors":"Rui Sha, Yangsheng Chen*, Tong Xu, Guanglei Yang, Li Xu, Heidi Qunhui Xie* and Bin Zhao, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 4","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":0.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/envhealth.4c00189","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144374466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Eldon Carlos Q. Gomes, Vívian N. Gonçalves, Marliete C. da Costa, Gustavo José C. d. Freitas, Daniel A. Santos, Susana Johann, Jefferson Bruno S. Oliveira, Tatiane A. d. Paixão, Peter Convey and Luiz H. Rosa*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 4","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":0.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/envhealth.4c00213","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144344714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Qing Yang, Xiaole Zhao, Kejia Wu, Qingqing Yu, Qiao Wang, Jingguang Li, Yongning Wu and Xin Liu*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 4","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":0.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/envhealth.4c00120","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144374462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 4","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":0.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/ehv003i004_1925569","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144374458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Jiahui Ma, Mengzhen Wang, Ye Sun, Yunhao Zheng, Senchao Lai, Yingyi Zhang, Yan Wu, Chao Jiang and Fangxia Shen*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 4","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":0.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/envhealth.4c00216","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144374463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Kai Tao, Bin Zeng, Linghui Deng, Wei Zhang, Xianghong Zhou, Yuming Jin, Zilong Zhang, Weichao Huang, Xiaoli Zou, Yu Zhan, Ping Lu, Shi Qiu, Lu Yang* and Qiang Wei*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 4","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":0.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/envhealth.4c00143","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144374460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse Effects of Pesticides on the Ovary: Evidence from Epidemiological and Toxicological Studies","authors":"Linping Wang,&nbsp;Xiaochen Ma and Jing Liu*,&nbsp;","doi":"10.1021/envhealth.4c0024310.1021/envhealth.4c00243","DOIUrl":"https://doi.org/10.1021/envhealth.4c00243https://doi.org/10.1021/envhealth.4c00243","url":null,"abstract":"<p >Pesticides are widely used in agriculture, public health, and residences to control pests and insects. The safety of exposure to pesticides has raised concerns due to their presence in the environment and their potential effects on human health. The ovary is the major female reproductive organ and is considered a potential target organ for pesticide toxicity. This comprehensive Review examines the adverse effects of pesticide exposure on the ovary based on evidence from human biomonitoring, epidemiological studies, and toxicological studies. Epidemiological studies have shown that pesticide exposures are associated with early/delayed menarche, menstrual cycle disorders, early menopause, long time to pregnancy, polycystic ovary syndrome, primary ovarian insufficiency, infertility, and implantation failure in women. Both <i>in vivo</i> and <i>in vitro</i> studies have shown that exposure to pesticides disrupts the estrous cycle, reduces the follicle pool, alters hormone levels, and impairs oocyte maturation. Mechanisms of action of pesticides on ovarian function include effects on steroid receptors, hormone synthesis, oxidative stress, inflammation, epigenetic modifications, and signaling pathways. Gaps in knowledge and further research needs include prospective cohort studies with adequate sample sizes to elucidate the effects of different classes of pesticides (especially emerging insecticides, herbicides and fungicides) and mixture exposures on ovarian health, the development of effective toxicological models that can approximate or simulate realistic human exposure scenarios, and the translation of toxicological findings into measurable indicators that can be used in human health risk assessment. In summary, this Review aims to improve the understanding of the risk to women’s reproductive health from exposures to pesticides and to provide insights into strategies for preventing and managing reproductive health risks.</p>","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 6","pages":"575–595 575–595"},"PeriodicalIF":0.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/envhealth.4c00243","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144320721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse Effects of Pesticides on the Ovary: Evidence from Epidemiological and Toxicological Studies.","authors":"Linping Wang, Xiaochen Ma, Jing Liu","doi":"10.1021/envhealth.4c00243","DOIUrl":"10.1021/envhealth.4c00243","url":null,"abstract":"<p><p>Pesticides are widely used in agriculture, public health, and residences to control pests and insects. The safety of exposure to pesticides has raised concerns due to their presence in the environment and their potential effects on human health. The ovary is the major female reproductive organ and is considered a potential target organ for pesticide toxicity. This comprehensive Review examines the adverse effects of pesticide exposure on the ovary based on evidence from human biomonitoring, epidemiological studies, and toxicological studies. Epidemiological studies have shown that pesticide exposures are associated with early/delayed menarche, menstrual cycle disorders, early menopause, long time to pregnancy, polycystic ovary syndrome, primary ovarian insufficiency, infertility, and implantation failure in women. Both <i>in vivo</i> and <i>in vitro</i> studies have shown that exposure to pesticides disrupts the estrous cycle, reduces the follicle pool, alters hormone levels, and impairs oocyte maturation. Mechanisms of action of pesticides on ovarian function include effects on steroid receptors, hormone synthesis, oxidative stress, inflammation, epigenetic modifications, and signaling pathways. Gaps in knowledge and further research needs include prospective cohort studies with adequate sample sizes to elucidate the effects of different classes of pesticides (especially emerging insecticides, herbicides and fungicides) and mixture exposures on ovarian health, the development of effective toxicological models that can approximate or simulate realistic human exposure scenarios, and the translation of toxicological findings into measurable indicators that can be used in human health risk assessment. In summary, this Review aims to improve the understanding of the risk to women's reproductive health from exposures to pesticides and to provide insights into strategies for preventing and managing reproductive health risks.</p>","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 6","pages":"575-595"},"PeriodicalIF":0.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12186281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 3","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":0.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/ehv003i003_1914321","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144438434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Sujuan Zhao,&nbsp;Yumeng Sun,&nbsp;Jiayao Duan,&nbsp;Tianxu Zhang,&nbsp;Yuchun Xiao,&nbsp;Yumin Zhu,&nbsp;Yibo Jia,&nbsp;Wenjue Zhong and Lingyan Zhu*,&nbsp;","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 3","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":0.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/envhealth.4c00158","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144438439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}