Journal of the American Nutrition Association最新文献

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Association Between Adherence to EAT-Lancet Diet and Risk of Hypertension: An 18-Year National Cohort Study in China. 坚持 EAT-Lancet 饮食与高血压风险之间的关系:中国一项为期 18 年的全国队列研究。
IF 6.8 4区 医学
Journal of the American Nutrition Association Pub Date : 2024-09-05 DOI: 10.1080/27697061.2024.2399826
Lifu Lei, Haixia Qin, Yushi Chen, Yu Sun, Wenwei Yin, Shiwen Tong
{"title":"Association Between Adherence to EAT-Lancet Diet and Risk of Hypertension: An 18-Year National Cohort Study in China.","authors":"Lifu Lei, Haixia Qin, Yushi Chen, Yu Sun, Wenwei Yin, Shiwen Tong","doi":"10.1080/27697061.2024.2399826","DOIUrl":"https://doi.org/10.1080/27697061.2024.2399826","url":null,"abstract":"<p><strong>Objective: </strong>The EAT-Lancet Commission has proposed an EAT-Lancet diet (ELD), also known as a planetary health diet (PHD), which is environmentally sustainable and promotes human health. However, the association between this diet and the risk of hypertension remains unclear. This study aimed to determine whether adherence to ELD was associated with a lower risk of hypertension.</p><p><strong>Methods: </strong>11,402 adults without hypertension at baseline from the China Health and Nutrition Survey were included. The PHD score was used to evaluate ELD adherence, with higher scores reflecting better compliance. Cox proportional hazards regression analysis was utilized to estimate the hazard ratio (HR) with a 95% confidence interval (CI). Additionally, a subgroup analysis was performed to identify the possible effect modifiers, and a mediation analysis was conducted to explore the mediation effects of anthropometric measurements on the association between ELD and hypertension.</p><p><strong>Results: </strong>A total of 3993 participants (35%) developed hypertension during 93,058 person-years of follow-up. In the covariate-adjusted model, hypertension risk was reduced in the highest quartile participants compared to the lowest quartile of the PHD score (adjusted HR: 0.79, 95%CI: 0.71-0.87; <i>P</i>-trend < 0.001), which remained significant after sensitivity analysis. Notably, the association was also observed in isolated systolic hypertension, isolated diastolic hypertension, and systolic-diastolic hypertension. Subgroup analysis revealed that the inverse association between the PHD score and hypertension risk was more pronounced in nonsmokers and high-sodium intake consumers than in smokers and low-sodium consumers (<i>P</i>-interaction < 0.05). Additionally, mediation analysis revealed that 23.3% of the association between the PHD score and hypertension risk was mediated by the waist-to-height ratio.</p><p><strong>Conclusion: </strong>Our findings suggest that a higher adherence to ELD is associated with a lower risk of hypertension. These results emphasize that ELD may serve as a potential strategy to prevent hypertension.</p>","PeriodicalId":29768,"journal":{"name":"Journal of the American Nutrition Association","volume":null,"pages":null},"PeriodicalIF":6.8,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Bidirectional Association between Internet Use, Sleep Quality and Eating Behavior: A Cross-Sectional Study in Northwestern Thrace Region in Türkiye. 互联网使用、睡眠质量和饮食行为之间的双向关联:图尔基耶西北色雷斯地区的一项横断面研究。
IF 6.8 4区 医学
Journal of the American Nutrition Association Pub Date : 2024-09-05 DOI: 10.1080/27697061.2024.2399845
Murat Gürbüz, Hatice Merve Bayram
{"title":"The Bidirectional Association between Internet Use, Sleep Quality and Eating Behavior: A Cross-Sectional Study in Northwestern Thrace Region in Türkiye.","authors":"Murat Gürbüz, Hatice Merve Bayram","doi":"10.1080/27697061.2024.2399845","DOIUrl":"https://doi.org/10.1080/27697061.2024.2399845","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to examine the complex associations between Internet addiction, sleep disturbances, and disordered eating behaviors.</p><p><strong>Methods: </strong>This cross-sectional study included 646 students from 17 high schools in Edirne, Türkiye between December 2023 and May 2024. A face-to-face questionnaire was administered to assess demographic characteristics, Internet addiction (YIAT), sleep quality (PSQI), and eating behavior (TFEQ-R21).</p><p><strong>Results: </strong>In total, 644 students completed the study. The prevalence of Internet addiction among adolescents was 16.3%, with a similar prevalence among male and female adolescents. The prevalence of poor sleep quality among adolescents was 6.4%, and this trend was more pronounced in male adolescents, with an incidence of 13.0%. A weak positive correlation was observed between Internet addiction and disordered eating behavior. Additionally, a moderate positive correlation was observed between poor sleep quality and disordered eating behavior. Gender, maternal education level, Internet addiction, and poor sleep quality were significant predictors of eating disorders in adolescents.</p><p><strong>Conclusion: </strong>The findings of our study are of significant value in providing insights into the development of programs designed to prevent undesired eating behaviors.</p>","PeriodicalId":29768,"journal":{"name":"Journal of the American Nutrition Association","volume":null,"pages":null},"PeriodicalIF":6.8,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Relationship Between Central Obesity and Osteoarthritis in US Adults: The Mediating Role of Biological Aging Acceleration. 美国成年人中心性肥胖与骨关节炎之间的关系:生物老化加速的中介作用
IF 6.8 4区 医学
Journal of the American Nutrition Association Pub Date : 2024-09-04 DOI: 10.1080/27697061.2024.2389398
Qiang He, Jie Mei, Chengxin Xie, Zhen Wang, Xin Sun, Mengmeng Xu
{"title":"The Relationship Between Central Obesity and Osteoarthritis in US Adults: The Mediating Role of Biological Aging Acceleration.","authors":"Qiang He, Jie Mei, Chengxin Xie, Zhen Wang, Xin Sun, Mengmeng Xu","doi":"10.1080/27697061.2024.2389398","DOIUrl":"https://doi.org/10.1080/27697061.2024.2389398","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to investigate the association between central obesity and the risk of osteoarthritis, and the mediating role of biological age and biological aging advance in this relationship.</p><p><strong>Methods: </strong>The study is based on data from the National Health and Nutrition Examination Survey (NHANES) for the years 2005-2018. Thirteen commonly used clinical traits were used to calculate the Klemera-Doubal method age (KDM-Age) and phenotypic age (Pheno-Age) as two measures of biological aging. Additionally, KDM-Age advance and Pheno-Age advance were calculated as two measures of biological aging advance. Weighted multivariable logistic regression was used to analyze the association between central obesity and the risk of osteoarthritis (OA). Mediation analysis was then applied to elucidate the role of biological aging and biological aging advance in this relationship.</p><p><strong>Results: </strong>A total of 31,162 subjects aged ≥20 years were included in this study, of which 3,964 subjects reported having OA (14%). Compared to the Non-OA group, the OA group showed significantly higher proportions of central obesity, KDM-Age, KDM-Age advance, PhenoAge, and PhenoAge advance. Compared to the Non-central obesity group, the central obesity group had higher KDM-Age, KDM-Age advance, PhenoAge, PhenoAge advance, and a higher risk of OA (<i>p</i> < 0.05). Additionally, higher KDM-Age, KDM-Age advance, PhenoAge, and PhenoAge advance were positively correlated with the risk of OA (<i>p</i> < 0.05). Mediation analysis revealed that part of the association between central obesity and the risk of OA was mediated by KDM-Age, KDM-Age advance, PhenoAge, and PhenoAge advance (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>Central obesity increases the risk of OA, with part of this association being mediated by biological aging and biological aging advance.</p>","PeriodicalId":29768,"journal":{"name":"Journal of the American Nutrition Association","volume":null,"pages":null},"PeriodicalIF":6.8,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142126862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Additive Interaction Between Insulin Resistance, Chronic Low-Grade Inflammation and Vitamin D Deficiency on the Risk of Type 2 Diabetes Mellitus: A Cohort Study. 胰岛素抵抗、慢性低度炎症和维生素 D 缺乏对 2 型糖尿病风险的叠加作用:一项队列研究
IF 6.8 4区 医学
Journal of the American Nutrition Association Pub Date : 2024-09-01 Epub Date: 2024-05-13 DOI: 10.1080/27697061.2024.2352401
Salam Bennouar, Abdelghani Bachir Cherif, Yazid Aoudia, Samia Abdi
{"title":"Additive Interaction Between Insulin Resistance, Chronic Low-Grade Inflammation and Vitamin D Deficiency on the Risk of Type 2 Diabetes Mellitus: A Cohort Study.","authors":"Salam Bennouar, Abdelghani Bachir Cherif, Yazid Aoudia, Samia Abdi","doi":"10.1080/27697061.2024.2352401","DOIUrl":"10.1080/27697061.2024.2352401","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to explore, on an additive scale, the combined effect of the association between insulin resistance (IR), chronic low-grade inflammation (CLGI) and vitamin D deficiency (VDD) on the risk of type 2 Diabetes Mellitus (T2DM).</p><p><strong>Methods: </strong>This is a cohort study, including 1484 non-diabetic subjects, followed for a period of four years. 25 hydroxy-vitamin D (25OHD), hypersensitive C-reactive protein (HsCRP) and triglyceride-glucose index were assessed. Based on VDD and CLGI, the population was subdivided into 4 exposure groups. Analysis was performed both in the case of IR and without IR. Cox proportional regression and additive interaction were applied to explore cumulative effects of exposure.</p><p><strong>Results: </strong>At follow-up, 162 newly diagnosed cases of T2DM were identified. TYG index (RR = 4.0[2.8-5.6]), HsCRP (RR = 1.6 [1.4-1.7]) and 25OHD (RR = 0.96 [0.39-0.98]) were all significantly associated with the risk of T2DM (<i>p</i> < 0.01). The highest excess risk was recorded in patients cumulating simultaneously IR, CLGI and VDD (RR= 8.4[3.6-19.8], <i>p</i> < 0.0001). The additive interaction was significant, the excess risk linked to the interaction RERI = 10.5[1.43-19.7], the proportion attributable to the combined effect: AP = 0.61[0.37-0.85], and the interaction was synergistic: synergy index: 2.8[1.42-5.69].</p><p><strong>Conclusion: </strong>Baseline levels of TYG index, 25OHD and HsCRP are strongly predictive of future T2DM, and their joint effects are additive and synergistic. Interventional studies are therefore warranted in order to evaluate whether vitamin D supplementation, combined with appropriate anti-inflammatory therapies, is effective as a preventive strategy to reduce the risk of T2DM.</p>","PeriodicalId":29768,"journal":{"name":"Journal of the American Nutrition Association","volume":null,"pages":null},"PeriodicalIF":6.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140917286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Insulin Sensitivity of Adipocytes is Improved by Pomegranate Mesocarp Through Reduced Oxidative Stress and Inflammation. 石榴中果皮通过减少氧化应激和炎症改善脂肪细胞对胰岛素的敏感性
IF 6.8 4区 医学
Journal of the American Nutrition Association Pub Date : 2024-09-01 Epub Date: 2024-05-22 DOI: 10.1080/27697061.2024.2353295
Piteesha Ramlagan, Philippe Rondeau, Emmanuel Bourdon, Theeshan Bahorun, Vidushi S Neergheen
{"title":"Insulin Sensitivity of Adipocytes is Improved by Pomegranate Mesocarp Through Reduced Oxidative Stress and Inflammation.","authors":"Piteesha Ramlagan, Philippe Rondeau, Emmanuel Bourdon, Theeshan Bahorun, Vidushi S Neergheen","doi":"10.1080/27697061.2024.2353295","DOIUrl":"10.1080/27697061.2024.2353295","url":null,"abstract":"<p><strong>Objective: </strong>Inflammatory phenomena and increase in oxidative stress in cell physiopathology progression render therapeutic strategies based on nutritional antioxidants necessary. It was thus aimed at assessing the effectiveness of the pomegranate mesocarp extract (PME) on differentiation of preadipocytes to adipocytes in the presence/absence of hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>), a model mimicking insulin resistance.</p><p><strong>Method: </strong>The effect of PME on lipid accumulation, protein expression of antioxidant, inflammatory and adipogenic biomarkers, reactive oxygen species production, activity of antioxidant enzymes and secretion of IL-6 has been evaluated during the differentiation of preadipocytes to adipocytes, in the presence or absence of H<sub>2</sub>O<sub>2</sub>.</p><p><strong>Results: </strong>H<sub>2</sub>O<sub>2</sub> reduced the expression of the regulator of insulin sensitivity PPARγ and suppressed adipocyte differentiation. PME counteracted the effect of H<sub>2</sub>O<sub>2</sub>. The latter induced a higher level of fat accumulation by promoting the expressions of the adipogenic markers PPARγ, C/EBPα, FABP4 and CD36 as compared to the control and the H<sub>2</sub>O<sub>2</sub>-treated differentiating cells. During the progression of adipogenesis, highest increase (<i>p</i> < 0.05) in IL-6 secretion, by 3.16 and 3.85 folds, was observed on day 2 of differentiation in control and H<sub>2</sub>O<sub>2</sub>-treated cells, respectively, compared to day 0. PME significantly decreased (<i>p</i> < 0.01) the secretion of the cytokine in addition to suppressing the expression of NFκB. PME also prevented the reduction of superoxide dismutase, catalase and glutathione peroxidase activities that occurred during adipogenesis, by at most 33%, 119% and 42%, respectively.</p><p><strong>Conclusion: </strong>These findings indicate that PME efficiently improves insulin sensitivity and can significantly counteract oxidative stress and inflammation.</p>","PeriodicalId":29768,"journal":{"name":"Journal of the American Nutrition Association","volume":null,"pages":null},"PeriodicalIF":6.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141076973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mild Dehydration Triggered by Exercise Reduces Cognitive Performance in Children, But Does Not Affect Their Motor Skills. 运动引发的轻度脱水会降低儿童的认知能力,但不会影响他们的运动技能。
IF 6.8 4区 医学
Journal of the American Nutrition Association Pub Date : 2024-09-01 Epub Date: 2024-06-05 DOI: 10.1080/27697061.2024.2362709
Sinem Yüksel, Mustafa Akıl
{"title":"Mild Dehydration Triggered by Exercise Reduces Cognitive Performance in Children, But Does Not Affect Their Motor Skills.","authors":"Sinem Yüksel, Mustafa Akıl","doi":"10.1080/27697061.2024.2362709","DOIUrl":"10.1080/27697061.2024.2362709","url":null,"abstract":"<p><strong>Objective: </strong>Children face the risk of dehydration in varying amounts during the day due to reasons such as physical activity, sweating, eating salty foods and drinking carbonated beverages. It is assumed that dehydration can lead to impaired motor skills and cognitive performance since it affects brain function. However, inconsistencies in study results, test times and problems caused by heat stress make new research mandatory. In our research, we examined the effects of exercise-induced mild dehydration on motor skills and cognitive performance in active/sedentary boys who do/do not do regular physical activities in their daily lives.</p><p><strong>Methods: </strong>The study included 112 boys who do regular physical activity (<i>n</i>:57; 12.40 ± 0.49<sub>age</sub>) and sedentary (<b>n</b>:55; 12.49 ± 0.50<sub>age</sub>). The children were given a 12-h hydration program. Mild dehydration was created by giving exercises after hydration measurements. In case of hydration and mild dehydration, Bruininks-Oseretsky Motor Proficiency and d2 attention test were applied to the children. For comparison, Repeated Measures ANOVA and Bonferroni post-hoc test was performed at the second level.</p><p><strong>Results: </strong>According to the hydration and mild dehydration comparison results, there was no difference in total score of Fine Motor Skill Sensitivity, Fine Motor Skill Integration, Hand Dexterity and Bidirectional Coordination, Balance, Running Speed and Agility, Hand-Arm Coordination, Strength, and BOT-2 in children. There was a decrease in both groups in terms of Focused Attention, Processing Speed, Accuracy, Concentration Performance and Attention Span.</p><p><strong>Conclusion: </strong>As a result, mild dehydration is associated with daily physical activity in children (physical education classes, etc.) or it can easily occur due to food/beverage preferences. It may affect children's performance of school curriculum and extracurricular activities. It shows that maintaining optimal hydration is important.</p>","PeriodicalId":29768,"journal":{"name":"Journal of the American Nutrition Association","volume":null,"pages":null},"PeriodicalIF":6.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perturbed Lipid Metabolism Transduction Pathways in SARS-CoV-2 Infection and Their Possible Treating Nutraceuticals. SARS-CoV-2感染中紊乱的脂质代谢传导途径及其可能的治疗保健品
IF 6.8 4区 医学
Journal of the American Nutrition Association Pub Date : 2024-09-01 Epub Date: 2024-05-28 DOI: 10.1080/27697061.2024.2359084
Amrita Shukla, Ankita Singh, Smriti Tripathi
{"title":"Perturbed Lipid Metabolism Transduction Pathways in SARS-CoV-2 Infection and Their Possible Treating Nutraceuticals.","authors":"Amrita Shukla, Ankita Singh, Smriti Tripathi","doi":"10.1080/27697061.2024.2359084","DOIUrl":"10.1080/27697061.2024.2359084","url":null,"abstract":"<p><p>The coronavirus disease 2019 (COVID-19) epidemic has evolved into an international public health concern. Its causing agent was <i>SARS-CoV-2</i> (severe acute respiratory syndrome coronavirus 2), a lipid bilayer encapsulated virus. Lipids have relevance in the host's viral cycle; additionally; viruses have been speculated to manipulate <i>lipid signaling</i> and production to influence the lipidome of host cells. SARS-CoV-2 engages the host lipid pathways for replication, like fatty acid synthesis activation <i>via</i> upregulation of AKT and SREBP pathway and inhibiting lipid catabolism by AMPK and PPAR deactivation. Consequently, lipoprotein levels are altered in most cases, i.e., raised LDL, TG, VLDL levels and reduced HDL levels like a hyperlipidemic state. Apo lipoproteins, a subsiding structural part of lipoproteins, may also impact viral spike protein binding to host cell receptors. In a few studies conducted on COVID-19 patients, maintaining Apo lipoprotein levels has also shown antiviral activity against SARS-CoV-2 infection. It was speculated that several potent hypolipidemic drugs, such as statins, hydroxychloroquine, and metformin, could be used as add-on treatment in COVID-19 management. Nutraceuticals like Garlic, Fenugreek, and vinegar have the potency to lower the lipid capability acting <i>via</i> these pathways. A link between COVID-19 and post-COVID alteration in lipoprotein levels has not yet been fully understood. In this review, we try to look over the possible modifications in lipid metabolism due to SARS-CoV-2 viral exposure, besides the prospect of focusing on the potential of lipid metabolic processes to interrupt the viral cycle.</p>","PeriodicalId":29768,"journal":{"name":"Journal of the American Nutrition Association","volume":null,"pages":null},"PeriodicalIF":6.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141158255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lipid Profile and Atherogenic Risk Assessment in Nigerian Breast Cancer Patients - A Cross-Sectional Study. 尼日利亚乳腺癌患者的血脂概况和致动脉粥样硬化风险评估--一项横断面研究。
IF 6.8 4区 医学
Journal of the American Nutrition Association Pub Date : 2024-09-01 Epub Date: 2024-05-28 DOI: 10.1080/27697061.2024.2353289
Ogochukwu O Izuegbuna, Hannah O Olawumi, Olayide S Agodirin, Samuel A Olatoke
{"title":"Lipid Profile and Atherogenic Risk Assessment in Nigerian Breast Cancer Patients - A Cross-Sectional Study.","authors":"Ogochukwu O Izuegbuna, Hannah O Olawumi, Olayide S Agodirin, Samuel A Olatoke","doi":"10.1080/27697061.2024.2353289","DOIUrl":"10.1080/27697061.2024.2353289","url":null,"abstract":"<p><strong>Background: </strong>The lipid profile and atherogenic risk indices in Nigerian breast cancer patients are largely unknown. This study evaluated the lipid profile and atherogenic risk indices of breast cancer patients in Nigeria.</p><p><strong>Methods: </strong>This study involved 45 primarily diagnosed breast cancer patients and 50 normal control subjects. Total cholesterol, triglyceride, and High-density lipoprotein cholesterol (HDL-C) were measured. Low-density lipoprotein cholesterol (LDL-C) was calculated according to Friedewald formula. Atherogenic index of plasma (AIP), Atherogenic coefficient (AC), TC/HDL-C (Castelli I) and LDL-C/HDL-C (Castelli II) risk indices were all calculated. The Framingham risk assessment was calculated and categorized.</p><p><strong>Results: </strong>The study group had significantly higher triglycerides (TG), and atherogenic indices than the control group (<i>p</i> < 0.001), while HDL-Cholesterol (HDL-C) was significantly lower in the study group (<i>p</i> < 0.001). Total cholesterol and LDL-Cholesterol (LDL-C) had a significant positive correlation with age (<i>r</i> = 0.283, <i>p</i> < 0.018; <i>r</i> = 0.272, <i>p</i> < 0.023); TG was significantly positively correlated with systolic and diastolic blood pressure (<i>r</i> = 0.320. <i>p</i> < 0.007; <i>r</i> = 0.334, <i>p</i> < 0.005); HDL-C had a significant negative correlation with BMI, systolic and diastolic blood pressure (<i>r</i> = -0.252, <i>p</i> < 0.035; <i>r</i> = -0.29, <i>p</i> < 0.015; <i>r</i> = -0.329, <i>p</i> < 0.005). The lipid ratios (TC/HDL-C, LDL-C/HDL-C) were significantly positively correlated with body mass index (BMI), systolic and diastolic blood pressure. The Framingham Risk Score showed that only 2 subjects in the study group (4.4%) were at a high risk of having a cardiovascular event.</p><p><strong>Conclusion: </strong>Breast cancer patients have a higher prevalence of dyslipidaemia, and cardiovascular risk than the normal population.</p>","PeriodicalId":29768,"journal":{"name":"Journal of the American Nutrition Association","volume":null,"pages":null},"PeriodicalIF":6.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141158194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dietary Flavonoid and Subclass Intakes are not Associated with Markers of Bone Health in U.S. Adults Age 50+ Years. 美国 50 岁以上成年人的膳食类黄酮和亚类摄入量与骨骼健康指标无关。
IF 6.8 4区 医学
Journal of the American Nutrition Association Pub Date : 2024-09-01 Epub Date: 2024-06-03 DOI: 10.1080/27697061.2024.2358532
Xichen Wang, Yang Lu, Taylor C Wallace
{"title":"Dietary Flavonoid and Subclass Intakes are not Associated with Markers of Bone Health in U.S. Adults Age 50+ Years.","authors":"Xichen Wang, Yang Lu, Taylor C Wallace","doi":"10.1080/27697061.2024.2358532","DOIUrl":"10.1080/27697061.2024.2358532","url":null,"abstract":"<p><strong>Background: </strong>Dietary flavonoid intakes have been associated with improved markers of bone health in Chinese and Scottish cohorts, but little data exist in middle aged to older adults in the United States.</p><p><strong>Objectives: </strong>The objective of our research was to assess if dietary flavonoid intakes are associated with bone mineral density (BMD), bone mineral content (BMC), and bone area of the lumbar spine and femoral neck in a nationally representative population of middle aged to older U.S. adults. We further sought to investigate if relationships of the main flavonoid subgroups (i.e., anthocyanins, flavan-3-ols, flavanones, flavones, flavonols, and isoflavones) exist, as a secondary objective.</p><p><strong>Methods: </strong>Cross-sectional data from individuals aged 50+ years enrolled in the 2017-2018 National Health and Nutrition Examination Survey (NHANES) were used in our analyses (<i>N</i> = 2590). Weighted multivariate logistic regression models were used to investigate the relationship between quartiles of flavonoid intake and BMD, BMC, and bone area of the lumbar spine and femoral neck of participants.</p><p><strong>Results: </strong>Mean age of participants was 63.4 ± 0.52 years and 64.1 ± 0.52 years for men and women, respectively. Average total flavonoid intake was 217 ± 19.4 mg/day and 306 ± 26.9 mg/day for men and women, respectively. Total flavonoid intakes were not significantly associated with BMD, BMC, or bone area of the femoral neck or lumbar spine in male or female participants. Flavonoid subclass intakes were also not consistently associated with improved markers of bone health.</p><p><strong>Conclusion: </strong>Although several limitations exist, this cross-sectional analysis of U.S. adults aged 50+ years provides contradictory evidence to the hypothesis that higher flavonoid and flavonoid subclass intakes beneficially impacts markers of bone health. Large prospective cohort investigations that better capture long-term dietary flavonoid intake and ascertain fractures the primary outcome, as well as randomized controlled trials, are needed to fully elucidate the effects flavonoids on bone health.</p>","PeriodicalId":29768,"journal":{"name":"Journal of the American Nutrition Association","volume":null,"pages":null},"PeriodicalIF":6.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141238399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact Plant-Based Diets Have on Athletic Performance and Body Composition: A Systematic Review. 植物性膳食对运动表现和身体成分的影响:系统回顾
IF 6.8 4区 医学
Journal of the American Nutrition Association Pub Date : 2024-09-01 Epub Date: 2024-06-24 DOI: 10.1080/27697061.2024.2365755
Nicole Presti, Tegan Mansouri, Molly K Maloney, David Hostler
{"title":"The Impact Plant-Based Diets Have on Athletic Performance and Body Composition: A Systematic Review.","authors":"Nicole Presti, Tegan Mansouri, Molly K Maloney, David Hostler","doi":"10.1080/27697061.2024.2365755","DOIUrl":"10.1080/27697061.2024.2365755","url":null,"abstract":"<p><p>Plant-based diets have gained popularity among athletes in recent years. Some believe that plant-based diets will improve performance owing to higher intakes of carbohydrates and antioxidants. Some believe it that will harm performance due to lower intakes of complete protein and creatine. This systemic review was conducted using Covidence software. A literature search of PubMed, Embase (Elsevier), CINAHL Plus (EBSCO), and Web of Science was completed on 22 March 2022. Following the development of clear objectives and a research question that identified the population, intervention, comparison, and outcomes, initial search criteria and keywords were identified. Extracted results totaled 2249, including 797 duplicates. The initial screening resulted in 1437 articles being excluded. The remaining 15 articles proceeded to full-text screening. A final 8 articles were included in the review, with 7 excluded. This paper will review the impact plant-based diets have on athletic performance and body composition in healthy young adults aged 18 to 45 years.</p>","PeriodicalId":29768,"journal":{"name":"Journal of the American Nutrition Association","volume":null,"pages":null},"PeriodicalIF":6.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141447192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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