International Journal of Cardiology Cardiovascular Risk and Prevention最新文献

{"title":"Nonepisodic angioedema with eosinophilia following a rose-thorn prick injury","authors":"Kimitoshi Matsuo ,&nbsp;Hidenori Takahashi ,&nbsp;Hiroki Nagamatsu ,&nbsp;Ryutaro Hirose ,&nbsp;Yuka Yamada ,&nbsp;Hiroaki Takei ,&nbsp;Naoya Toba ,&nbsp;Mio Toyama-Kousaka ,&nbsp;Shinichiro Ota ,&nbsp;Miwa Morikawa ,&nbsp;Masaharu Shinkai","doi":"10.1016/j.ijcrp.2024.200301","DOIUrl":"https://doi.org/10.1016/j.ijcrp.2024.200301","url":null,"abstract":"<div><h3>Background</h3><p>Nonepisodic angioedema with eosinophilia (NEAE) is a condition marked by angioedema and significant eosinophilia and often linked with atopic dermatitis. It predominantly affects young Asian women and occurs more frequently in the autumn and winter. Despite over 100 reported cases, its etiology and pathogenesis remain unclear.</p></div><div><h3>Case presentation</h3><p>A 23-year-old Japanese female florist presented with acute arm swelling following rose-thorn pricks to her hands and fingers in spring. One week later, she developed progressive symmetrical non-pitting edema in her lower legs and a 3 kg weight gain without any rash. She had a history of oral allergy syndrome to apples and pears for which allergen-specific IgE were previously detected. Blood tests showed significant eosinophilia (14,930 cells/μL) and elevated thymus and activation-regulated chemokine (TARC) levels (12,864 pg/mL). Thyroid disease, autoimmune disorders, and hematologic malignancies were ruled out. Normal cardiac markers and a whole-body computed tomography excluded visceral organ involvement. She was diagnosed with NEAE and treated with oral prednisolone, which resolved the edema within 10 days. Prednisolone was tapered gradually on an outpatient basis without recurrence.</p></div><div><h3>Conclusion</h3><p>A review of the literature indicates that NEAE triggered by subcutaneous antigen exposure may not follow the typical age or seasonal patterns. Direct subcutaneous antigen exposure, including rose-thorn pricks, can trigger NEAE. Clinicians should consider NEAE in atypical presentations and thoroughly investigate preceding episodes.</p></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"22 ","pages":"Article 200301"},"PeriodicalIF":2.3,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000667/pdfft?md5=6b57b831709599dd537cdfa177f294c2&pid=1-s2.0-S2772487524000667-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141423678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary hypertension exacerbated by hereditary hemorrhagic telangiectasia combined with pulmonary arteriovenous fistula and pregnancy status: A case report","authors":"Wanjiao Chen ,&nbsp;Yuliang Long ,&nbsp;Dandan Chen,&nbsp;Shengyu Hao,&nbsp;Lihua Guan ,&nbsp;Daxin Zhou","doi":"10.1016/j.ijcrp.2024.200300","DOIUrl":"https://doi.org/10.1016/j.ijcrp.2024.200300","url":null,"abstract":"<div><h3>Background</h3><p>Hereditary hemorrhagic telangiectasia (HHT) is an uncommon autosomal dominant condition. The combination of pregnancy and HHT can exacerbate pulmonary hypertension (PH) and, in severe cases, lead to fatality.</p></div><div><h3>Case presentation</h3><p>The case we presented is a 28-year-old multiparous woman. She developed chest tightness and dyspnea in the second trimester of pregnancy, which was not taken seriously at that time, and the symptoms worsened postpartum. Echocardiography showed elevated pulmonary artery pressure (PAP) and the computerized tomographic pulmonary angiogram revealed a significant pulmonary arteriovenous malformation. The patient's condition continued to deteriorate despite treatment to reduce pulmonary hypertension. We reviewed and updated the history of omission, recurrent epistaxis during pregnancy, and similar symptoms running in her family. Combined with the whole exon genetic testing report revealing the ACVRL1 gene mutation at chr12:52308295, the diagnosis of HHT was established. Four months later, a transcatheter closure of the pulmonary arteriovenous fistula was performed, with satisfying outcomes presenting a decrease of more than 15 mmHg in the pulmonary artery pressure. As of right now, the patient's status is stable during the outpatient follow-up.</p></div><div><h3>Conclusions</h3><p>HHT is a rare condition that typically occurs alongside abnormal communication between pulmonary veins and arteries, leading to a high-flow state in the pulmonary circulation. A pulmonary hypertension crisis can also be triggered by the patient's pregnancy, which further increases blood volume. By reducin<span>https://www.ecdc.europa.eu/sites/default/files/documents/Methods-for-the%20detection-and-characterisation-of-SARS-CoV-2-variants-first-update-WHO-20-Dec-2021.pdfg</span><svg><path></path></svg> pulmonary vascular flow, catheter closure of the pulmonary arteriovenous fistula decreases pulmonary arterial pressure.</p></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"22 ","pages":"Article 200300"},"PeriodicalIF":1.9,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000655/pdfft?md5=46e6f964d95051afc16c35717a173066&pid=1-s2.0-S2772487524000655-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141480888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rigid ring vs. flexible band for tricuspid valve repair in patients with tricuspid valve regurgitation: A systematic review and meta-analysis","authors":"Shadi Alaa Abdelaal ,&nbsp;Mahmoud Tarek Hefnawy ,&nbsp;Enas Ewais ,&nbsp;Naydeen Mostafa ,&nbsp;Ahmed Mohamed Abozaid ,&nbsp;Adel Mouffokes ,&nbsp;Amnir Moustapha ,&nbsp;Mohamed Mohamed ,&nbsp;Hazem S. Ghaith ,&nbsp;Alaa Ramadan ,&nbsp;Nathan Ezie Kengo ,&nbsp;Ahmed Negida","doi":"10.1016/j.ijcrp.2024.200296","DOIUrl":"https://doi.org/10.1016/j.ijcrp.2024.200296","url":null,"abstract":"<div><h3>Background &amp; objectives</h3><p>Rigid ring and Flexible band are techniques used to repair tricuspid valve regurgitation. The comparison between both techniques' effectiveness is controversial in the literature. We conducted this systematic review and meta-analysis to compare the safety and efficacy of rigid ring versus flexible band for tricuspid valve repair in patients with tricuspid valve regurgitation.</p></div><div><h3>Methods</h3><p>We conducted a PRISMA-compliant systematic review and meta-analysis. A systematic search was performed in major databases, including PubMed, Scopus, Web of Science, and Cochrane CENTRAL to identify relevant published studies. Data were extracted and analyzed using Stata (version 17 for Mac) and Revman (version 5.4 for Windows).</p></div><div><h3>Results</h3><p>Twelve studies were included in this meta-analysis. Total number of patients was 4259. The rigid ring wasn't superior to the flexible band in terms of postoperative tricuspid regurgitation RR 0.74, 95 % CI (0.43–1.27) (P = 0.29). However, the results were not homogeneous. After employing sensitivity analysis, the significance of the pooled effect estimate didn't change, showing no significant difference between the two annuloplasty RR 0.72, 95%CI (0.45–1.15). On the other hand, the rigid ring was associated with a higher bypass time than the flexible band (RR 4.85, P = 0.00). There were no differences between the two groups in terms of hospital stay, ICU stays, prolonged ventilation, mechanical ventilation time, annuloplasty size, stroke, concomitant mitral valve surgery, concomitant aortic valve surgery, atrial fibrillation, pacemaker implantation, low cardiac output, in-hospital death, or late death (all P &gt; 0.05).</p></div><div><h3>Conclusion</h3><p>Our study findings suggested no difference between rigid ring compared to flexible band regarding the rates of postoperative tricuspid regurgitation; however, rigid ring may encompass a higher bypass time. Therefore, further research is required to ensure our findings.</p></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"22 ","pages":"Article 200296"},"PeriodicalIF":1.9,"publicationDate":"2024-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000618/pdfft?md5=9aed2c1aa6c12e009ce3cb659e4ba50d&pid=1-s2.0-S2772487524000618-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141480886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of drugs in residual cardiovascular risk: A systematic review of the literature","authors":"Mario Andres Hernandez-Sómerson ,&nbsp;Fernando Montoya-Agudelo ,&nbsp;Gustavo Huertas-Rodriguez","doi":"10.1016/j.ijcrp.2024.200298","DOIUrl":"10.1016/j.ijcrp.2024.200298","url":null,"abstract":"<div><h3>Background</h3><p>The objective of this research is to evaluate the efficacy and safety of drugs in the residual risk in any of its three components: lipid, inflammatory and thrombotic risk.</p></div><div><h3>Methods</h3><p>A systematic review was conducted of randomized clinical trials that included as a primary outcome, at least one of the conditions related to atherosclerotic cardiovascular disease. The databases used were PUBMED/MEDLINE, Scopus and <span>ClinicalTrials.gov</span><svg><path></path></svg>. The risk of bias of the studies was assessed using the Risk of Bias 2 tool.</p></div><div><h3>Results</h3><p>and discussion: 18 studies were included in the analysis. Half of the studies had low risk of bias or some concerns. Several drugs were effective in reducing the primary outcome: ethyl eicosapentaenoeic acid (17.2 % E-EPA versus 22 % placebo HR: 0.75; 95 % CI 0.68–0.83; p &lt; 0.001), colchicine in stable coronary artery disease (6.8 % vs placebo 9.6 %, HR 0.59, 95 % CI 0.57–0.83; p &lt; 0.001), Canakinumab (150 mg vs placebo ARR 15 %, HR 0.85, 95 % CI 0.74–0.98; p = 0.021) and Rivaroxaban with Aspirin in stable atherosclerotic disease (4.1 % versus aspirin 5.4 %, HR 0.76, 95 % CI 0.66–0.86, P &lt; 0.001). Serious adverse events did not differ between study groups, except for a higher rate of bleeding with the use of combination antithrombotic therapy.</p></div><div><h3>Conclusion</h3><p>The residual risk can be reduced through the use of different drugs that act by modifying atherogenic lipid levels, modulating inflammatory pathways and the risk of thrombosis, with an acceptable safety profile in most studies.</p></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"22 ","pages":"Article 200298"},"PeriodicalIF":1.9,"publicationDate":"2024-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000631/pdfft?md5=c9368d4e4e6a0f6d57a6fbec4dc758df&pid=1-s2.0-S2772487524000631-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141409322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipoprotein (a) and lipid-lowering treatment from the perspective of a cardiac surgeon. An impact on the prognosis in patients with aortic valve replacement and after heart transplantation","authors":"Stanisław Surma ,&nbsp;Michał O. Zembala ,&nbsp;Bogusław Okopień ,&nbsp;Maciej Banach","doi":"10.1016/j.ijcrp.2024.200297","DOIUrl":"https://doi.org/10.1016/j.ijcrp.2024.200297","url":null,"abstract":"<div><p>Lipoprotein(a) is a recognized risk factor for ASCVD. There is still no targeted therapy for Lp(a), however, drugs such as pelacarsen, olpasiran, zerlasiran, lepodisiran and muvalaplin are in clinical trials and have been shown to be effective in significantly reducing Lp(a) levels. Moreover, elevated Lp(a) levels significantly affect the prognosis of patients after aortic valve replacement (AVR) and heart transplantation (HTx). Therefore, the assessment of Lp(a) concentration in these patients will allow for a more accurate stratification of their cardiovascular risk, and the possibility of lowering Lp(a) will allow for the optimization of this risk. In this article, we summarized the most important information regarding the role of Lp(a) and lipid-lowering treatment in patients after AVR and HTx.</p></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"22 ","pages":"Article 200297"},"PeriodicalIF":2.3,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S277248752400062X/pdfft?md5=ece16801c983d7af3acc1740f98b7385&pid=1-s2.0-S277248752400062X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141290803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Referral of the heart failure patient from cardiology and internal medicine department: Same patients and same rehabilitative approach?","authors":"Venturini Elio","doi":"10.1016/j.ijcrp.2024.200277","DOIUrl":"https://doi.org/10.1016/j.ijcrp.2024.200277","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"21 ","pages":"Article 200277"},"PeriodicalIF":2.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000424/pdfft?md5=d664969e5f258bb09759e9db694b9fc5&pid=1-s2.0-S2772487524000424-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141249812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What the ITACARE-P Light-Heart and Sweet-Heart projects have taught us","authors":"Bruno Passaretti","doi":"10.1016/j.ijcrp.2024.200274","DOIUrl":"https://doi.org/10.1016/j.ijcrp.2024.200274","url":null,"abstract":"<div><p>Sweet Heart and Light Heart represent the first two educational formats of ITACARE-P, a recently established scientific association that joins various professionals with the aim of promoting all activities related to Cardiac Prevention and Rehabilitation. These educational formats represent opportunities for updating, comparing and sharing ideas among experts in order to standardize behaviors on hot topics. Pathologies in the metabolic field were chosen: diabetes mellitus and obesity, especially due to the cardiologist's possibility of prescribing drugs belonging to the SGLT2-i and GLP-RA classes, which have been shown to have a cardioprotective and nephroprotective effect, thus carrying a favorable influence on cardiovascular mortality. Sweet Heart and Light Heart were structured in a series of lectures alternated with “peer-to-peer” discussions; the possibilities offered by Italian National Health Service refundability in the prescription of these drugs and the difficulties that can be encountered in communicating this therapy to patients, particularly in the case of obesity where the purchase of the drug is at the patient's own expense, were examined. The results of this initiative was the drafting and publication of a position paper involving the entire Scientific Committee of the Association concerning the management of the patient suffering from diabetes mellitus in Cardiac Rehabilitation, with the peculiarities that concern the approach to the patient in this setting, such as the prescription of physical exercise in the same way as a drug, the introduction of process and outcome indicators, and the search for an anti-atherogenic or rather hemodynamic effect.</p></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"21 ","pages":"Article 200274"},"PeriodicalIF":2.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000394/pdfft?md5=fba3dc824fa9bdca53c39b96b93f35b9&pid=1-s2.0-S2772487524000394-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141249811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced machine learning for estimating vascular occlusion percentage in patients with ischemic heart disease and periodontitis","authors":"Pradeep Kumar Yadalam,&nbsp;Santhosh B. Shenoy,&nbsp;Raghavendra Vamsi Anegundi,&nbsp;Seyed Ali Mosaddad,&nbsp;Artak Heboyan","doi":"10.1016/j.ijcrp.2024.200291","DOIUrl":"10.1016/j.ijcrp.2024.200291","url":null,"abstract":"<div><h3>Objective</h3><p>The study aimed to assess the efficacy of advanced machine learning algorithms in estimating the percentage of vascular occlusion in ischemic heart disease (IHD) cases with periodontitis.</p></div><div><h3>Methods</h3><p>This study involved 300 IHD patients aged 45 to 65 with stage III periodontitis undergoing coronary angiograms. Dental and periodontal examinations assessed various factors. Coronary angiograms categorized patients into three groups based on artery stenosis. Clinical data were processed, outliers were identified, and machine learning algorithms were applied for analysis using the orange tool, including confusion matrices and receiver operating characteristic (ROC) curves for assessment.</p></div><div><h3>Results</h3><p>The results showed that Random Forest, Naïve Bayes, and Neural Networks were 97 %, 84 %, and 92 % accurate, respectively. Random Forest did exceptionally well in identifying the severity of conditions, with 95.70 % accuracy for mild cases, 84.80 % for moderate cases, and a perfect 100.00 % for severe cases.</p></div><div><h3>Conclusions</h3><p>The current study, using Periodontal Inflammatory Surface Area (PISA) scores, revealed that the Random Forest model accurately predicted the percentage of vascular occlusion.</p></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"21 ","pages":"Article 200291"},"PeriodicalIF":2.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000564/pdfft?md5=c8cfbdc7eccef6e783d03ba3ec286019&pid=1-s2.0-S2772487524000564-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141138296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex and gender differences in patients with acute coronary syndromes","authors":"Alessandra Pratesi","doi":"10.1016/j.ijcrp.2024.200276","DOIUrl":"10.1016/j.ijcrp.2024.200276","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"21 ","pages":"Article 200276"},"PeriodicalIF":2.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000412/pdfft?md5=b731f7b4008453124b5c5571502c5e0d&pid=1-s2.0-S2772487524000412-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141041858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of the biomarker score in determining the risk of heart failure in diabetics in Goma, North Kivu in the Democractic Republic of the Congo","authors":"Ferdinand Ng'ekieb Mukoso,&nbsp;Aliocha Natuhoyila Nkodila,&nbsp;Hippolyte Nani tuma Situakibanza,&nbsp;Stannislas Okitotsho Wembonyama,&nbsp;Zacharie Kibendelwa Tsongo","doi":"10.1016/j.ijcrp.2024.200263","DOIUrl":"10.1016/j.ijcrp.2024.200263","url":null,"abstract":"<div><h3>Background</h3><p>The use of biomarkers, such as N-terminal pro-brain natriuretic peptide (NTpBNP), high-sensitivity C-reactive protein (hs-CRP) and high-sensitivity troponin (hs-TnI) is an alternative approach to detect the risk of heart failure (HF), but data on this approach are fragmentary in sub-Saharan Africa. The objective of this study is to determine the correlation between the risk of heart failure and the score of biomarkers in the population of asymptomatic diabetics in the city of GOMA.</p></div><div><h3>Methods</h3><p>Asymptomatic diabetics in the city of Goma were cross-sectionally recruited at the Center of the Association of Diabetics in Congo (ADIC) in Goma, DRC during the period from February 5 to 19, 2023. The risk of insufficiency heart rate at 5 years was determined using pulse pressure. The biomarker score was calculated using NTproBNP, hs-CRP, hs-troponin and left ventricular hypertrophy (LVH). The association between the risk of heart failure and the biomarker score was evaluated using the logistic regression test at the threshold of p &lt; 0.05.</p></div><div><h3>Results</h3><p>Of a total of 408 diabetic patients examined, 29.9% had presented a risk of heart failure. The risk of heart failure was higher in patients with a high biomarker score (57.7%), in patients with type 1 diabetes (60%) and in patients with type 2 diabetes (57.1%). Independent risk of biomarker score on occurrence of heart failure. The risk of heart failure was multiplied by 2 if the biomarker score was intermediate (OR: 2.19, 95% CI: 1.11–4.34) and by 5 if the biomarker score was high (OR: 4.73, 95% CI: 1.84–6.20).</p></div><div><h3>Conclusion</h3><p>The biomarker score is associated with the risk of heart failure in our study via the increase in the score elements as reported in European studies.</p></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"21 ","pages":"Article 200263"},"PeriodicalIF":2.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S277248752400028X/pdfft?md5=5c0ab8482917b84a04eebd6a9889188b&pid=1-s2.0-S277248752400028X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140399853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}