Chinese Journal of Analytical Chemistry最新文献

{"title":"Determination of 17 phthalate esters in water using GC–MS combined with magnetic solid phase extraction with Fe3O4@GO","authors":"Qinghua YANG ,&nbsp;Zhimin HE ,&nbsp;Yilan SHI ,&nbsp;Jinxin WANG ,&nbsp;Qianying QIU ,&nbsp;Honghai DENG ,&nbsp;Wenhui PING","doi":"10.1016/j.cjac.2024.100378","DOIUrl":"https://doi.org/10.1016/j.cjac.2024.100378","url":null,"abstract":"<div><p>In this study, a new technique was developed which combines magnetic solid phase extraction (MSPE) and gas chromatography-mass spectrometer (GC–MS), for the analysis of 17 phthalate esters (PAEs). First, a composite of iron (used as the magnetic part) and graphene oxide (GO) was synthesized for application in MSPE. Scanning electron microscop, X-ray diffraction and infrared spectroscopy were used to characterize this material. Finally, magnetic graphene oxide (Fe₃O₄@GO) was used to extract PAEs from water samples. Various parameters relevant to the extraction were optimized, such as the amount of adsorbent employed, adsorption time, luent solvent types and volume, and sample pH. These optimum conditions resulted in calibration curves for the 17 PAEs, showing linear relationships between concentration and response at concentrations of 25 to 2500 µg L⁻¹ with correlation coefficients from 0.9983 to 1.000. Limit of detection and limit of quantitationfor the PAEs ranged from 0.030 to 0.12 µg L⁻¹ and 0.10–0.40 µg L⁻¹, respectively. The recovery rates for these compounds in spiked samples were ranging from 81.5% to 109% with relative standard deviation less than 6.12%. The effectiveness of method was further demonstrated by its use in detecting 17 PAEs in samples of drinking and bottled water. Compounds such as DEP, DIBP, DBP, and DCHP were identified. These results thus highlight the suitability of Fe₃O₄@GO as an adsorbent for concentrating and purifying PAEs in water samples.</p></div>","PeriodicalId":277,"journal":{"name":"Chinese Journal of Analytical Chemistry","volume":"52 4","pages":"Article 100378"},"PeriodicalIF":1.2,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1872204024000239/pdfft?md5=9f7978982d2c02f13a52d190fe5575de&pid=1-s2.0-S1872204024000239-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140351911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Near-infrared spectroscopy combined with deep convolutional generative adversarial network for prediction of component content in melt-cast explosive","authors":"Qiang LIU,&nbsp;Jiajing ZHAO,&nbsp;Baosong DAN,&nbsp;Pengfei SU,&nbsp;Gao ZHANG","doi":"10.1016/j.cjac.2024.100379","DOIUrl":"https://doi.org/10.1016/j.cjac.2024.100379","url":null,"abstract":"<div><p>Rapid and nondestructive prediction of component content is the key to improve industrial production efficiency. However, limited data sets also result in low generalization capabilities of the model, and it is time-consuming to obtain a large amount of content reference values and costly. Here, near infrared (NIR) spectroscopy technique combined with deep convolutional generated countermeasure network (DCGAN) was used to predict the trinitrotoluene (TNT) content of the melt-cast explosive. DCGAN was used to simultaneously extend its spectral data and content data. After several iterations, fake data were produced, which was very similar to the experimental data. The partial least squares (PLS) regression model was established and the performance was compared before and after data enhancement. The results showed that this method not only improved the performance of regression model, but also solved the problem of requiring large number of training data.</p></div>","PeriodicalId":277,"journal":{"name":"Chinese Journal of Analytical Chemistry","volume":"52 4","pages":"Article 100379"},"PeriodicalIF":1.2,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1872204024000240/pdfft?md5=92e6c47db351579b32645ec77201975e&pid=1-s2.0-S1872204024000240-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140351912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fingerprint, multi-component content determination, and mechanism in treating Intracerebral Hemorrhage of Tao-He-Cheng-Qi granule","authors":"Zhiyong ZHONG ,&nbsp;Riping XIAO ,&nbsp;Dequan ZHU ,&nbsp;Guowei LI ,&nbsp;Wanling ZENG ,&nbsp;Dongmei MAI ,&nbsp;Jingyi QIU ,&nbsp;Xiangdong CHEN ,&nbsp;Wenhui LUO ,&nbsp;Wencai YE ,&nbsp;Dongmei SUN","doi":"10.1016/j.cjac.2024.100367","DOIUrl":"10.1016/j.cjac.2024.100367","url":null,"abstract":"<div><p>Tao-He-Cheng-Qi granule (THCQ) was derived from Tao-He-Cheng-Qi Decoction, which has been proved to be one of the effective traditional Chinese medicines (TCMs) applied in the treatment of Intracerebral Hemorrhage (ICH). The objective of this investigation was to study the quality control of THCQ and explore its potential mechanism in treating ICH. According to the results, 20 batches of THCQ had similar chromatographic fingerprints. The similarities of chromatograms of the 20 batches were 0.937–0.998 and 15 major chromatographic peaks were identified as the common peaks for the quality control of THCQ. Subsequently, four analytical methods were successfully established to determine 7 index components of THCQ, respectively, which then were applied in 20 batches of THCQ to determine the content of these index components. Besides, animal experiments were conducted to explore the mechanism of THCQ in the treatment of ICH. After a three-day treatment, behavioral changes and brain histopathological evaluations of SD rats showed that THCQ dose-dependently improved the symptoms of rats with ICH. The results of immunohistochemical evaluations showed that THCQ reduced the expressions of TNF-α and IL-1β. The results of protein expressions detected by ELISA revealed that THCQ dose-dependently reduced Notch1 level and increased the expression of VEGFR. Collectively, the mechanisms of THCQ for treating ICH might be closely relevant to the downregulation of Notch and NF-κB and the upregulation of VEGFR. These findings provided insight for studies in investigating the quality control and further clinical application of THCQ.</p></div>","PeriodicalId":277,"journal":{"name":"Chinese Journal of Analytical Chemistry","volume":"52 3","pages":"Article 100367"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1872204024000124/pdfft?md5=729b9f6ca470c16596cbd3b4abfa89cb&pid=1-s2.0-S1872204024000124-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139766587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overlooking pH decrease induced by ATP (or ATP-2Na) results in false positive response of rhodamine spirolactam derivatives to millimolar ATP","authors":"Liyi MA ,&nbsp;Lixuan MU ,&nbsp;Lushan HUANG ,&nbsp;Guangwei SHE ,&nbsp;Wensheng SHI","doi":"10.1016/j.cjac.2024.100369","DOIUrl":"10.1016/j.cjac.2024.100369","url":null,"abstract":"<div><p>An outstanding fluorescent probe for adenosine 5′-triphosphate (ATP) in the millimolar range will shed deep light on the physiological role of ATP. Many fluorescentprobes based on rhodamine spirolactam derivatives have been developed for this purpose and claimed to detect millimolar ATP excellently, where ATP or adenosine 5′-triphosphate disodium salt (ATP-2Na) is employed to examine their response to ATP. However, in this work, it was found that both millimolar ATP and ATP-2Na could significantly decrease the pH of the common buffer solution even for several units. Considering the dependence of the rhodamine spirolactam fluorescence on pH, a series of rhodamine spirolactam-based probes was synthesized to investigate their fluorescence response to pH and ATP-2Na. The results demonstrated that the fluorescence response of the probes to millimolar ATP-2Na indeed resulted from both ATP-2Na itself and the pH decrease induced by ATP-2Na. Furthermore, it was evidenced that acidic pH was crucial for the probes to produce fluorescence response to millimolar ATP-2Na itself, and the rhodamine spirolactam-based probes would show poor sensitivity to millimolar ATP-2Na at near-natural pH. Accordingly, the previous conclusion that the rhodamine spirolactam-based probes could detect millimolar ATP excellently was almost erroneous, and might mislead the design and practice of intracellular ATP probe in the future. This work notes that attention should be paid to the physiochemical properties of the analyte and the environmental changes produced by the target analyte.</p></div>","PeriodicalId":277,"journal":{"name":"Chinese Journal of Analytical Chemistry","volume":"52 3","pages":"Article 100369"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1872204024000148/pdfft?md5=4c8bd441de418902b90d24a51bb367d0&pid=1-s2.0-S1872204024000148-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140054087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly sensitive dual-mode assay for tetracycline detection","authors":"Kai Yang ,&nbsp;Ruiqi Zhu ,&nbsp;Zhongping Li ,&nbsp;Shaomin Shuang ,&nbsp;Yan Zhai ,&nbsp;Chuan Dong","doi":"10.1016/j.cjac.2024.100363","DOIUrl":"10.1016/j.cjac.2024.100363","url":null,"abstract":"<div><p>A dualmode tetracycline (TC) assay was developed based on a colloidally stable mixture of TC-specific aptamer stabilized AuNPs (Apt-stabilized AuNPs) and graphite carbon nitride nanosheets (g-C₃N₄) for sensitive detection of TC. The presence of TC in the solution could be identified based on the colorimetric and fluorescent signals. This dual-mode assay requires no salt during TC detection and has high sensitivity, allowing detection limits (LOD) of TC to 1.0 × 10⁻¹⁶ M with a wide dynamic detection range (six orders of magnitude, from 5.0 × 10⁻¹⁶ to 5.0 × 10⁻¹¹ M), and exhibits good selectivity for TC over other metal cations, antibiotics, amino acids, and proteins. The mechanism of this dual-mode assay for TC detection was investigated in detail. Moreover, the amount of TC in actual samples (spiked drinking water and milk) was successfully monitored. The findings provide valuable guidance in developing an advanced platform for detecting TC and other antibiotics.</p></div>","PeriodicalId":277,"journal":{"name":"Chinese Journal of Analytical Chemistry","volume":"52 3","pages":"Article 100363"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1872204024000082/pdfft?md5=32dd33091d106ae1d02dd1585d26319c&pid=1-s2.0-S1872204024000082-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139559595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A nanozyme based wearable device for colorimetric monitoring of UV radiation exposure in sunlight","authors":"Guofen ZHOU ,&nbsp;Linlin YU ,&nbsp;Wenlong GUO ,&nbsp;Zhongwei JIANG ,&nbsp;Lianzhe HU ,&nbsp;Min WANG","doi":"10.1016/j.cjac.2024.100377","DOIUrl":"10.1016/j.cjac.2024.100377","url":null,"abstract":"<div><p>In this study, nanozyme is used for monitoring the dose of ultraviolet (UV) in sunlight for the first time. We find that nitrogen-doped carbon dots (N-doped C-dots) can effectively catalyze the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) under different UV region including UVA, UVB, and UVC. In comparison, the N-doped C-dots fail to show the catalytic activity under visible light. The finding is applied for distinguishing UV light and visible light through the color change of TMB. More importantly, the photo-oxidation TMB catalyzed by N-doped C-dots can work well in a near neutral pH, which is beneficial for its application in wearable device due to the reducing of acid corrosion. Finally, a wearable bracelet is fabricated by integrating N-doped C-dots and TMB into hydrogels. The bracelet is used for monitoring the UV exposure in sunlight. The color change of TMB in the bracelet can be clearly observed by naked eyes or quantified by a smartphone. The bracelet is also used for distinguishing different weather condition such as sunny/cloudy or different place such as indoor/outdoor during a sunny day. This study provides the first example of nanozyme in wearable UV sensor and will stimulate the applications of nanozyme in wearable device.</p></div>","PeriodicalId":277,"journal":{"name":"Chinese Journal of Analytical Chemistry","volume":"52 3","pages":"Article 100377"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1872204024000227/pdfft?md5=a4c268cd9fcf52567851814905bb63bb&pid=1-s2.0-S1872204024000227-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140198509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A highly sensitive ratiometric electrochemical aptasensor for prostate specific antigen detection based on toehold-mediated strand displacement reaction","authors":"Ping WANG ,&nbsp;Zhimin GUAN ,&nbsp;Yaoyao XIE,&nbsp;Sanqiang LI","doi":"10.1016/j.cjac.2024.100376","DOIUrl":"10.1016/j.cjac.2024.100376","url":null,"abstract":"<div><p>In this work, a novel ratiometric electrochemical aptasensor was designed for prostate specific antigen (PSA) detection based on toehold-mediated strand displacement reaction (TMSDR). For PSA detection, PSA could bind with the aptamer sequence in hairpin probe 1 (HP1), and HP1/PSA complex was obtained. Then, in the presence of S3 DNA, HP1/PSA could trigger two TMSDR processes by hybridizing with Fc-S2/S1 double-stranded DNA, which would generate a large amount of Fc-S2 and recycle HP1/PSA. This enabled the hybridization of Fc-S2 with methylene blue labeled thiolated hairpin probe 2 (MB-HP2) immobilized on the electrode surface, causing MB molecules away from the electrode and Fc close to the electrode. Thus, with the increasing PSA concentrations, the current of MB (<em>I</em>_MB) decreased and the current of Fc (<em>I</em>_Fc) increased. The ratio of <em>I</em>_Fc/<em>I</em>_MB was shown to be linear with the logarithm of PSA concentration from 1 pg mL⁻¹ to 100 ng mL⁻¹, with a detection limit of 0.28 pg mL⁻¹. In addition, the aptasensor had good specificity, reproducibility, repeatability, and stability for PSA detection, and was successfully applied to spiked diluted human serum samples.</p></div>","PeriodicalId":277,"journal":{"name":"Chinese Journal of Analytical Chemistry","volume":"52 3","pages":"Article 100376"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1872204024000215/pdfft?md5=b52f9f3186009aadf1a8997e63d1fa23&pid=1-s2.0-S1872204024000215-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140154210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-effective layered double hydroxides/conductive polymer nanocomposites for electrochemical detection of wastewater pollutants","authors":"Morris KAMEL ,&nbsp;Gehad Abd EL-FATAH ,&nbsp;Amal ZAHER ,&nbsp;Ahmed A. FARGHALI ,&nbsp;Sarah I. OTHMAN ,&nbsp;Ahmed A. ALLAM ,&nbsp;Hassan Ahmed RUDAYNI ,&nbsp;Asmaa M. SALAH ,&nbsp;Mohamed E.M. HASSOUNA ,&nbsp;Rehab MAHMOUD","doi":"10.1016/j.cjac.2024.100368","DOIUrl":"https://doi.org/10.1016/j.cjac.2024.100368","url":null,"abstract":"<div><p>There is an urgent need to develop multifunctional cost-effective nanomaterials and nanocomposites that can be used in numerous applications while showing high efficiency and cheaper implementation compared to conventional techniques and/or materials. In this work, zinc/iron layered double hydroxide (LDH) and polyaniline (PANI) were synthesized as a model LDH/conductive polymer nanocomposite, which is a promising family of cheap multifunctional materials. This electrochemical properties of this nanocomposite was investigated for detection of heavy metal (HM) ions in water streams, using lead as a model HM . In the present work, zinc/iron LDH and PANI was assigned as carbon paste electrode modifier. The composite was fully characterized using various characterization techniques including X-ray diffraction (XRD), scanning electron microscope (SEM), and Fourier transform InfraRed (FTIR). The electrochemical redox reactions of lead (II) ions at the modified electrode interface were investigated using cyclic voltammetry (CV), differential pulse voltammetry (DPV), Accordingly, a linear relation of Pb²⁺ ions was achieved in the concentration range 1–80 µM with limit of detection (LOD) was 167.8 nM and limit of quantification (LOQ) was 559.4 nM. Furthermore, the cost of using such material for lead removal using a typical adsorption study was compared to using conventional inductively coupled plasma (ICP) or atomic absorption spectrometry (AAS) equipment for tracking HM removal during the adsorption process. Cost analysis revealed that the final overall cost of the modified carbon paste electrode is estimated as 1.25 USD. This cost represents less than 0.1% of the total cost required to conduct the same adsorption study using a typical ICP or AAS equipment. This composite can pave the road towards portable measurements for onsite detection of wastewater pollutants using cheap disposable-electrodes as compared to massive expensive off site equipment such as ICP and AAS.</p></div>","PeriodicalId":277,"journal":{"name":"Chinese Journal of Analytical Chemistry","volume":"52 3","pages":"Article 100368"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1872204024000136/pdfft?md5=6047563fbc8a63f9b91bb90300575335&pid=1-s2.0-S1872204024000136-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140016235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis, characterization and optimization of sulfonated poly-ether-ether-ketone (sPEEK)/functionalized carbon nanotubes (c-CNTs) nanocomposite membranes for fuel cell application","authors":"Mawlood Maajal Ali ,&nbsp;Ali Basem ,&nbsp;Ameer Azam ,&nbsp;S.J.A. Rizvi ,&nbsp;Farhan Lafta Rashid","doi":"10.1016/j.cjac.2024.100365","DOIUrl":"10.1016/j.cjac.2024.100365","url":null,"abstract":"<div><p>Poly-ether ketone (PEEK) was modified to sulfonated poly-ether ketone (sPEEK) by sulfonation process with a degree of sulfonation 49.5%. Carbon nanotubes were acid-treated with sulfuric acid and nitric acid solution (3:1, <em>v</em>/<em>v</em>) for functionalization. sPEEK and sPEEK/c-CNT membranes were prepared by solvent casting method using dimethyl sulfoxide (DMSO) as solvent. The experimental part was conducted as per design of experiment employing response surface methodology consisting three factors, namely (A) c-CNT (wt.%), (B) mixing temperature (°C), and (C) sPEEK concentration (mg/mL). The ion exchange capacity was found to increase with c-CNT (wt.%). Fourier-transform infrared spectroscopy confirms the sulfonation of PEEK. X-Ray diffraction investigates the influence of the sulfonation in the crystal structure of the sPEEK and sPEEK/c-CNT. Scanning electron microscopy images show that c-CNTs are dispersed well in the sPEEK matrix. The results showed slightly increasing water uptake and swelling ratio of the composites membranes. The analysis of variance (ANOVA) revealed that c-CNT (wt.%) is highly affecting the responses. Proton conductivity of sPEEK specimen is about 23.9 mS/cm, which is significantly increased to 57.0 mS/cm for sPEEK/0.12 c-CNT (wt.%) membrane suggesting its application for fuel cell.</p></div>","PeriodicalId":277,"journal":{"name":"Chinese Journal of Analytical Chemistry","volume":"52 2","pages":"Article 100365"},"PeriodicalIF":1.2,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1872204024000100/pdfft?md5=07a3b4cfdf42e979a31f06a24ca8c2d5&pid=1-s2.0-S1872204024000100-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139666727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smart sweat glucose detection system based on organic electrochemical transistor and near field communication","authors":"Xue-Tao ZHANG ,&nbsp;Ping LIU ,&nbsp;Ru-Ting WANG ,&nbsp;Qiong GONG ,&nbsp;Cheng FANG","doi":"10.1016/j.cjac.2024.100356","DOIUrl":"10.1016/j.cjac.2024.100356","url":null,"abstract":"<div><p>A smart glucose detection system based on organic electrochemical transistor and near field communication module was built to detect sweat sample. The system mainly consists of three parts: glucose sensor, electrochemical detection module and application. The basic three electrodes (gate, source and drain) were prepared by screen printing technology on the polyethylene terephthalate sheets selected as the substrate material. The gate electrode was multilayer modified with gold membrane, Prussian blue and glucose oxidase, and the channel between the source and drain was covered with a poly (3,4-ethylenedioxythiophene): poly (styrenesulfonate) film. The potential drop caused by the redox reaction of glucose on the gate electrode changed the response of source-drain current signal. The electrochemical detection module with near field communication function was customized to realize the functions of signal detection, amplification and data transmission. Conjunct with smart Android devices analyzed and processed the data stream from near field communication to display glucose test results. The high sensitivity attributed to the amplification function of the field effect device and high selectivity to the enzyme sensor realize the detection of glucose in simulated sweat, which paves the way to relevant glucose detection in diabetics without the need for invasive finger-stick blood sampling.</p></div>","PeriodicalId":277,"journal":{"name":"Chinese Journal of Analytical Chemistry","volume":"52 2","pages":"Article 100356"},"PeriodicalIF":1.2,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S187220402400001X/pdfft?md5=8b886c7f4a6486bbf84aad90ee6cfbd2&pid=1-s2.0-S187220402400001X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139465427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}