Chettinad Health City Medical Journal最新文献_第5页

Effect of Body Mass on Quadriceps Muscle Strength among Postmenopausal Women 绝经后妇女体重对股四头肌力量的影响

Chettinad Health City Medical Journal Pub Date : 2023-06-30 DOI: 10.24321/2278.2044.202326

Ketaki Yogesh Kulkarni

{"title":"Effect of Body Mass on Quadriceps Muscle Strength among Postmenopausal Women","authors":"Ketaki Yogesh Kulkarni","doi":"10.24321/2278.2044.202326","DOIUrl":"https://doi.org/10.24321/2278.2044.202326","url":null,"abstract":"Introduction: Obesity is a major public health problem, which can lead to a reduction in functional capacity and an increase in the risk of mortality. Along with this, there are detrimental effects of menopause which can cause a decrease in functional capacity. The aim of this study was to understand the effect of obesity or increased weight on quadriceps muscle strength as age-related morphological changes are more pronounced in quadriceps. Methods: Sixty postmenopausal women aged between 50 and 70 years were divided into two groups according to body mass index (BMI): obese (n = 35) and not obese (n = 25). To assess quadriceps muscle strength, a modified sphygmomanometer was used. The procedure was done 3 times and the mean score was recorded. The same procedure was done for both legs. Results: The results obtained by comparing the left and right quadriceps muscle with normal and increased body mass index show extreme significance with p value < 0.0001. Mean and standard deviation were used as measurements. Conclusion: Our results show obesity or increased weight causes a decrease in quadriceps muscle strength as observed in postmenopausal women with increased body mass index. How to cite this article:Kulkarni KY, Yadav T. Effect of Body Mass on Quadriceps Muscle Strength among Postmenopausal Women. Chettinad Health City Med J. 2023;12(2):41-45. DOI: https://doi.org/10.24321/2278.2044.202326","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"25 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136368375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phytochemical Analysis and Antibacterial Activity of Dipterocarpus turbinatus Leaf Extracts against Staphylococcus aureus and Klebsiella pneumoniae 杜鹃叶提取物对金黄色葡萄球菌和肺炎克雷伯菌的抑菌活性及植物化学分析

Chettinad Health City Medical Journal Pub Date : 2023-06-30 DOI: 10.24321/2278.2044.202334

Nijanthi P

{"title":"Phytochemical Analysis and Antibacterial Activity of Dipterocarpus turbinatus Leaf Extracts against Staphylococcus aureus and Klebsiella pneumoniae","authors":"Nijanthi P","doi":"10.24321/2278.2044.202334","DOIUrl":"https://doi.org/10.24321/2278.2044.202334","url":null,"abstract":"Introduction: In this research, Dipterocarpus turbinatus leaf extracts in aqueous, chloroform, ethanol, hexane, and methanol were examined for their phytochemical components and antimicrobial activity. Methods: Bacteria such as Staphylococcus aureus (a gram-positive bacterium) and Klebsiella pneumonia (a gram-negative bacterium) were tested for antimicrobial action. The extracts from the leaves demonstrated broad-spectrum anti-bacterial action against these microbes. Result: Acids, proteins, phenols, carbohydrates, flavonoids, alkaloids, glycosides, cardiac glycosides, steroids, tannins, starch, triterpenoids, and terpenoids were among the frequently found phytochemical components in D. turbinatus leaf extracts. Conclusion: Traditional herbal medicines, which are widely used in developed countries as well as in the developing world, can benefit greatly from the antimicrobial properties of these plants, which have been used by humans for centuries without showing any signs of toxicity. How to cite this article:Nijanthi P, Santhi S. Phytochemical Analysis and Antibacterial Activity of Dipterocarpus turbinatus Leaf Extracts against Staphylococcus aureus and Klebsiella pneumoniae. Chettinad Health City Med J. 2023;12(2):94-98. DOI: https://doi.org/10.24321/2278.2044.202334","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"98 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136369658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of Helfer Skin Tap (HST) Technique on Pain during Intramuscular Injection among Children Attending Immunisation Clinic - A Randomised Controlled Trial in South India 1393 1993年在南印度进行的一项随机对照试验:Helfer皮肤穿刺(HST)技术对参加免疫诊所的儿童肌肉注射时疼痛的疗效

Chettinad Health City Medical Journal Pub Date : 2023-06-23 DOI: 10.24321/2278.2044.202328

P Srinivasan

{"title":"Efficacy of Helfer Skin Tap (HST) Technique on Pain during Intramuscular Injection among Children Attending Immunisation Clinic - A Randomised Controlled Trial in South India 1393","authors":"P Srinivasan","doi":"10.24321/2278.2044.202328","DOIUrl":"https://doi.org/10.24321/2278.2044.202328","url":null,"abstract":"Background: Injections for vaccinations are found to be the most common cause of iatrogenic pain in childhood and the association of pain with such types of vaccinations may result in anxiety and discomfort for children as well as for their family members and the healthcare providers who administer them. Aim: This RCT has been conducted to evaluate the efficacy of the Helfer Skin Tap (HST) technique on pain among children receiving intramuscular immunisation. Materials and Methods: Quantitative research was carried out with the true experimental post-test only control group design among 40 attending the immunisation clinics selected by convenience sampling technique with random assignment. The intervention was administered by tapping at the injection site for 3 minutes before, during, and after vaccination in the experimental group. The pain was assessed with a standardised FLACC pain scale in both groups. Results: We analysed the data with chi-square test for homogeneity of sample characteristics and association with pain, and an independent t-test for the effectiveness of HST. There was a statistically significant reduction in pain among the experimental group after HST in comparison with the control group, and none of the variables had any association with pain in children. Conclusion: The study concluded that the HST technique was significantly effective in pain reduction among children undergoing intramuscular injections at an immunisation clinic. How to cite this article:Saritha V, Radha MS, Subhashini L, Srinivasan P. Efficacy of Helfer Skin Tap (HST) Technique on Pain during Intramuscular Injection among Children Attending Immunisation Clinic - A Randomised Controlled Trial in South India. Chettinad Health City Med J. 2023;12(2):56-62. DOI: https://doi.org/10.24321/2278.2044.202328","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"251 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136084253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Medical Inflation - Issues and Impact 医疗膨胀-问题和影响

Chettinad Health City Medical Journal Pub Date : 2023-06-23 DOI: 10.24321/2278.2044.202340

S Poongavanam

引用次数: 0

Diagnostic Manifestations (Istedlal wa Alamat) of Anaemia (Faqr al-Dam) in Ancient Unani Literature - A Review 古代乌纳尼文献中贫血的诊断表现(istedal wa Alamat

Chettinad Health City Medical Journal Pub Date : 2023-03-31 DOI: 10.24321/2278.2044.202313

Safder Husain

{"title":"Diagnostic Manifestations (Istedlal wa Alamat) of Anaemia (Faqr al-Dam) in Ancient Unani Literature - A Review","authors":"Safder Husain","doi":"10.24321/2278.2044.202313","DOIUrl":"https://doi.org/10.24321/2278.2044.202313","url":null,"abstract":"Anaemia has a long history, as evidenced by 4,000-year-old bone samples from Thailand that showed advanced signs of the disease. Man has known the importance of iron in health and sickness since the dawn of humanity. Egyptians, Indians, Greeks, and Romans were among the first to use iron as a medicine. In the 17th century, iron was used to cure chlorosis (green disease), which was commonly caused by an iron deficiency. The molecule of haemoglobin requires iron to function properly. It is the most effective therapy for treating anaemia caused by a haemoglobin deficiency for over 2000 years. The aetiological factors (Asbāb), types (Aqsaam), pathophysiology, and clinical manifestation (Istedlal wa Alȧmȧt) of anaemia have been described in the Unani ancient literature which may be very useful for early diagnosis of anaemia. Data for this review article were collected from ancient Unani books and other manuscripts. It was found that there are several clinical manifestations (Istedlal wa Alȧmȧt) of Faqr al-Damin ancient Unani literature that aid in the diagnosis and treatment of anaemia. This article may be quite helpful for the early diagnosis and treatment of anaemia through the Unani system of medicine.Keywords:Anaemia (Faqr al-Dam), Aetiological factors (Asbāb), Clinical manifestation (Istedlal wa Alȧmȧt), Types (Aqsaam), Pathophysiology of anaemia, PreventionIntroductionAncient Unani physicians believed that derangement of the liver, sūmizāj and Ḍu‘f al-kabid (weakness of hepatic faculties) or sometimes associated diseases results in impaired and improper production of blood causing anaemia.1-3The word Sū’al-Qinya was coined by Ismail Jurjani (12th AD). Sū means defect and Qinya means treasure, therefore anaemia might be considered a treasury defect.4 Other vernaculars of anaemia stated by contemporary physicians are Faqr al-Dam,Sū’al-Qinya, Qillat-i-dam, khoon-ki-kami, khoon ki mohtaji (ghareebi, nadari) and Fas̄ad al-Dam.5","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124832665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Narrative Review on the Anti-genotoxic Potential of Medicinal Plants in Ayurveda 阿育吠陀药用植物抗基因毒性研究综述

Chettinad Health City Medical Journal Pub Date : 2023-03-31 DOI: 10.24321/2278.2044.202312

A. Raj

引用次数: 0

In-silico and In-vitro Evaluation of the Anti-diabetic Potential of p-Propoxybenzoic Acid 对丙氧基苯甲酸抗糖尿病潜能的体内体外评价

Chettinad Health City Medical Journal Pub Date : 2023-03-31 DOI: 10.24321/2278.2044.202307

Keval Y. Raval

{"title":"In-silico and In-vitro Evaluation of the Anti-diabetic Potential of p-Propoxybenzoic Acid","authors":"Keval Y. Raval","doi":"10.24321/2278.2044.202307","DOIUrl":"https://doi.org/10.24321/2278.2044.202307","url":null,"abstract":"Background: p-propoxybenzoic acid (p-PBA) is reported as an active chemical constituent of medicinal plants that possess anti-diabetic activity. It is termed a Multiple-Designed Ligand (MDL) having the ability to block more than one enzyme. A molecular docking study justifies the binding ability of p-PBA with acarbose and NaVO4 which were considered standard compounds having the ability to block target enzymes. α-amylase inhibition assay was used as an in-vitro screening model to evaluate the activity of p-PBA against diabetes on an initial basis. Methods: For the molecular docking study, a PDB file of p-PBA was prepared and PDB files of α-amylase (1C8Q), α-glucosidase (5KZW) and PTP1B (5K9W) were procured. p-PBA was docked against the enzymes using the blind docking method. The binding score of p-PBA and standard with enzymes was obtained and compared. The percentage inhibition of an α-amylase enzyme by p-PBA was measured by using a DNS-modified α-amylase inhibition assay and half-maximal inhibitory concentration (IC50) was calculated. Results: p-PBA has a significant inhibitory effect against α-amylase, α-glucosidase, and PTP1B with docking scores of 8.43 ± 0.44 kcal/mol, 9.19 ± 0.49 kcal/mol, and 9.40 ± 0.47 kcal/mol respectively. IC50calculated from the results of α-amylase inhibition assay p-PBA was 56.59 μg/mL. Conclusion: A combination of in-silico and in-vitro methods assessed p-PBA’s anti-diabetic potential on an initial basis. A molecular docking study involving p-PBA concluded the affinity of p-PBA to α-amylase, α-glucosidase, and PTP1B was significantly correlated with the affinity of acarbose and NaVO4. In-vitro α-amylase assay validated the compound’s inhibitory action against the enzyme.","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124621673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Knowledge and Acceptance of COVID-19 Vaccination among Women of Reproductive Age Group 育龄妇女COVID-19疫苗接种的知识和接受程度

Chettinad Health City Medical Journal Pub Date : 2023-03-31 DOI: 10.24321/2278.2044.202308

Vijayalakshmi Kandasamy

{"title":"Knowledge and Acceptance of COVID-19 Vaccination among Women of Reproductive Age Group","authors":"Vijayalakshmi Kandasamy","doi":"10.24321/2278.2044.202308","DOIUrl":"https://doi.org/10.24321/2278.2044.202308","url":null,"abstract":"Background: The acceptability of COVID vaccine by reproductive age group women remains unknown. Hence the study was conducted to define the knowledge about the COVID-19 vaccine and its acceptance in a sample of women who were planning to get pregnant. Method: This is a prospective study conducted at Chettinad Hospital and Research Institute, Chennai, India on 157 women of reproductive age group during August-September 2022. Data were collected using a face-to-face questionnaire administered to women who attended the Obstetrics and Gynaecology OPD. Data were analysed using SPSS. Results: Of the 157 respondents, nearly half were in the age group of 20-32 years, and almost 72% of them were educated with the minimum qualification being higher secondary education. In the given study, 70.7% were urban and semi-urban residents and 29.3% were rural women. About 66% of them were employed and the rest were unemployed. Gravidity status showed no significant differences regarding awareness. Overall awareness was about 74.5% and acceptance was 70.7%. Conclusion: Though women are aware of the vaccines, there is hesitancy prevailing. Literacy plays an important role in vaccine awareness and acceptance. Women of reproductive age should be made aware that the COVID vaccine is safe for use. The side effects, if any, will also be mostly minor. Although vaccine trials have not been conducted on pregnant women, the beneficial effects of vaccination far outweigh the negligible risk, if any, to the foetus and the women were made aware of this information.","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"105 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132120770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Comparative Study on the Effect of Acupuncture and Neutral Hip Bath among Young Females with Primary Dysmenorrhea – A Prospective Randomised Trial 针刺与中性臀浴治疗年轻女性原发性痛经的比较研究——一项前瞻性随机试验

Chettinad Health City Medical Journal Pub Date : 2023-03-31 DOI: 10.24321/2278.2044.202303

Abhijna J

{"title":"A Comparative Study on the Effect of Acupuncture and Neutral Hip Bath among Young Females with Primary Dysmenorrhea – A Prospective Randomised Trial","authors":"Abhijna J","doi":"10.24321/2278.2044.202303","DOIUrl":"https://doi.org/10.24321/2278.2044.202303","url":null,"abstract":"Introduction: Dysmenorrhea is a common medical condition characterised by severe abdominal pain during menstruation. Dysmenorrhea with no obvious pelvic pathology is referred to as primary dysmenorrhea. Acupuncture and hydrotherapy are non-pharmacological interventions that help in reducing pain without any known adverse effects. The current study was aimed at understanding and comparing the effects of acupuncture with those of neutral hip bath on the symptoms and disability associated with primary dysmenorrhea. Methodology: In the present prospective randomised controlled trial, 70 females aged 21.54 ± 1.73 years fulfilling the study criteria were selected. Subjects were randomly divided into acupuncture and neutral hip bath groups. They were then assessed by the Visual analogue scale and Menstrual symptom questionnaire, outcomes variables assessed on the baseline, mid (30thday) and post (60th day) status of the intervention. Results: In the present study, analysis of variance (RMANOVA) on Visual analogue scale and Menstrual symptom questionnaire scores yielded significant variation among the conditions. Post hoc Tukey’s test showed a significant reduction in mean scores of both acupuncture and neutral hip bath groups. The outcomes variables taken during three intervals, pre vs mid, mid vs post, and pre vs post resulted in a p value ≤ 0.001, thus, suggesting the equal effectiveness of acupuncture and neutral hip bath in primary dysmenorrhea. Conclusion: The present study indicates that neutral hip bath was equally effective as acupuncture in the management of primary dysmenorrhea. It reduces the severity of dysmenorrhoeic pain and associated symptoms in young females.","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122733154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Study of Echocardiographic Assessment of Left Ventricular Abnormalities in Patients with Chronic Kidney Disease 慢性肾病患者左心室异常的超声心动图评价研究

Chettinad Health City Medical Journal Pub Date : 2023-03-31 DOI: 10.24321/2278.2044.202304

Mahesh G Patil

{"title":"A Study of Echocardiographic Assessment of Left Ventricular Abnormalities in Patients with Chronic Kidney Disease","authors":"Mahesh G Patil","doi":"10.24321/2278.2044.202304","DOIUrl":"https://doi.org/10.24321/2278.2044.202304","url":null,"abstract":"Introduction: Echocardiographic abnormalities are very common in end-stage renal disease (ESRD) patients and a wide spectrum of abnormalities are noted. In order to prevent mortality, periodic echocardiographic examination for early diagnosis of cardiac abnormalities and initiation of treatment is very important. Cardiac structural changes and altered function detected by echocardiography are common in patients with Chronic Kidney Disease (CKD) before commencing haemodialysis and it is also noticed as one of the important key outcome predictors. The heart and kidney are inevitably linked with haemodynamic and regulatory functions. Aims and Objectives: The aim was to study the prevalence of left ventricular abnormalities by echocardiography in patients with chronic kidney disease and to find out the correlation of left ventricular abnormalities and 2D echo indices with the severity of chronic kidney disease. Materials and Methods:The study was conducted in theDepartment of Medicine, Vinayaka Missions Kirupananda Variyar Medical College, Salem, Tamil Nadu. 100 patients were included in the study after considering the inclusion and exclusion criteria. It was a cross-sectional study conducted from February 2020 to April 2021. Results And Conclusion: The most common aetiology found with CKD was diabetes mellitus followed by hypertension which, in turn, was followed by obstructive uropathy and NSAID use. Among the study participants, only 20% had systolic dysfunction and only 28% had diastolic dysfunction. 72% of the study participants showed LVH and 28% had normal findings. A negative correlation was observed between systolic grading and CKD categories. No correlation was observed in our study between diastolic grading and CKD categories.","PeriodicalId":276735,"journal":{"name":"Chettinad Health City Medical Journal","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124744674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0