Proceedings of the 7th World Congress on Recent Advances in Nanotechnology最新文献

{"title":"In Silico Characterization of Nanomaterials","authors":"A. Colibaba, K. Kotsis, V. Lobaskin","doi":"10.11159/icnnfc22.170","DOIUrl":"https://doi.org/10.11159/icnnfc22.170","url":null,"abstract":"Extended Abstract Nanomaterials (NMs) and nanoparticles (NPs) lie at the core of many technological applications in medicine and pharmacology, as well as in the food, agriculture, electronics, and energy industries. They are also released in the environment through natural and incidental pathways. Despite our heavy reliance on NMs, the potential risk they pose to the environment and to the biological systems is still of major concern [1]. In this work, we evaluate intrinsic and extrinsic NM descriptors to aid in the prediction of biomolecular interactions at the surface of NMs and development of structure-activity relationships between their physicochemical characteristics and their toxicity [2]. Intrinsic properties are solely based on the molecular and electronic structure of the NM, while the extrinsic properties describe a NM that comes in contact with a protein in a solvent. The NM models for the calculation of intrinsic descriptors are associated with the core of the NM that is described as a periodic bulk material [2]. In this work, we present a database of calculated descriptors for several common NMs. The provided list contained various samples of NP (metals, oxides, minerals, polymers, and carbon-based compounds such as carbon nanotubes (CNTs) and graphene sheets) that were used in toxicological experiments. The intrinsic descriptors are evaluated by different theoretical approaches. The bandgap values of all bulk NMs were calculated using density functional theory (DFT) implemented in the SIESTA package [3]. The density of states obtained from the DFT calculation at the generalized gradient approximation is used to estimate the size of the bandgap.","PeriodicalId":276715,"journal":{"name":"Proceedings of the 7th World Congress on Recent Advances in Nanotechnology","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129501030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiscale Modelling of Milk Protein Interaction With Iron and Aluminum Surfaces","authors":"Parinaz Mosaddeghi Amini, J. Subbotina, V. Lobaskin","doi":"10.11159/icnnfc22.174","DOIUrl":"https://doi.org/10.11159/icnnfc22.174","url":null,"abstract":"In this work, the bionano interface structure is investigated by a methodology that accounts for the interaction between inorganic solid nanoparticles (NPs) and protein biological molecules at the interface The relationship between nanomaterial properties and the interaction with different materials is key to a deeper understanding and the design of new nanomaterials and nanoplatform systems. Here we are to study the interaction of cow milk protein with metals such as iron and aluminum used in milk processing. Milk are essential for applications ranging from nutrition to bio and chemical technology. Moreover, a variety of natural and anthropogenic sources introduce aluminum and iron into the food chain. Therefore, there are a number of pathways for aluminum and iron into milk and dairy products","PeriodicalId":276715,"journal":{"name":"Proceedings of the 7th World Congress on Recent Advances in Nanotechnology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129565673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Long-Acting Injectable Formulation of Rilpivirine Based On PLGA Microspheres","authors":"Yulia Ulianova, Yu. V. Ermolenko, V. Trukhan, Vladimir U. Ivanov, Ildar R. Iusupov, Alexander Alexander, S. Gelperina","doi":"10.11159/nddte22.143","DOIUrl":"https://doi.org/10.11159/nddte22.143","url":null,"abstract":"The rilpivirine-loaded spherical and monodisperse PLGA microspheres were produced by microfluidic technology. The technological parameters such as the flow rate ratio and the rilpivirine/PLGA ratio were optimized to ensure desired microspheres size and higher encapsulation efficiency of rilpivirine. The microspheres exhibited a continuous drug release characterized by only a minor burst effect. These results suggest that the PLGA microspheres loaded with rilpivirine is a promising approach to the injectable depot formulation of this drug.","PeriodicalId":276715,"journal":{"name":"Proceedings of the 7th World Congress on Recent Advances in Nanotechnology","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121640615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydrothermal growth: Influence of Process parameters to design TiO2 nanostructures","authors":"Walid Mnasri, S. Péralta, Xavier Sallenave","doi":"10.11159/icnnfc22.169","DOIUrl":"https://doi.org/10.11159/icnnfc22.169","url":null,"abstract":"Extended Abstract Over the past several decades, numerous research activities have been focused on fabrication of titanium oxide (TiO 2 ) films owing to their broad applications in various fields such as medicine [1] (cancer treatment, antimicrobial), energy [2] (water splitting, photovoltaic), environment (air and water purification), gas sensors, photocatalysis, and self-cleaning [3]. Currently, various deposition methods have been employed to develop the TiO 2 including sol gel [4], solvothermal, chemical vapor deposition, thermal oxidation and hydrothermal method [5]. When specifically compared to other methods, the hydrothermal method has many advantages: (i) the required equipment and processing conditions is easier, (ii) during crystallization processes, growing crystals/crystallites tend to reject impurities present in the growth environment, (iii) by changing the hydrothermal conditions (such as titanium precursor concentration, reaction time, reaction temperature, additives, substrate orientation, and pH of growth solution), crystalline products could be easily modified with different compositions, morphologies and structures. However, slight variations in these parameters result in significant alterations of the properties of TiO 2 . Herein, we report the formation chemistry, growth mechanism of TiO 2 nanostructures in the surface of FTO substrate. The effects of key hydrothermal experimental conditions have been discussed to understand the different obtained morphologies. Indeed, XRD and Raman analysis confirmed the formation of the rutile phase of TiO 2 . Morphological studies showed that we can obtain nanorods with","PeriodicalId":276715,"journal":{"name":"Proceedings of the 7th World Congress on Recent Advances in Nanotechnology","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128602649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in Nucleic Acid Medicine Delivery to the Brain","authors":"SM Moghimi","doi":"10.11159/nddte22.002","DOIUrl":"https://doi.org/10.11159/nddte22.002","url":null,"abstract":"- The phage display technology is widely used for identification and isolation of peptides that bind to a particular target with high affinity and specificity. Although a number of phage-derived peptides have been identified that bind to cerebral capillaries, conjugation of particulate drug delivery systems with such peptides have yielded disappointing results in brain targeting on intravenous injection [1]. To address these shortfalls, we introduced a phage mimetic termed NanoLigand Carriers (NLCs) to efficiently target and cross brain capillaries on intravenous injection [2]. NLCs are self-assemblies of a brain-specific phage display peptide conjugate that engage their targets through a hierarchical presentation of display peptides (e.g., as in protofilaments). On intravenous injection, NLCs reach the brain in substantial quantities without disrupting the integrity and functionality of the BBB. NLCs accommodate a wide range of guest molecules and targets two cellular receptors. On reaching the brain-parenchyma, NLCs carrying therapeutic nucleic acids engage with microglial cells and neurons, exerting unprecedented pharmacological effects without inducing inflammation and metabolic perturbations [2]. NLCs therefore overcome previous limitations in active targeting with particulate drug carriers, including those decorated with phage display peptides.","PeriodicalId":276715,"journal":{"name":"Proceedings of the 7th World Congress on Recent Advances in Nanotechnology","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128908925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optical Properties of Al2O3-Ni-Al Nano-Composite Films","authors":"Y. Kang, W. Jang, Y. Seo, B. Kim","doi":"10.11159/icnnfc22.104","DOIUrl":"https://doi.org/10.11159/icnnfc22.104","url":null,"abstract":"Extended Abstract In the nature, there are a variety of organisms and minerals that produce colors as a result of nanostructures that interacting with light. This phenomenon is called structural colors. Structural colors are based on several basic optical effects, including thin layer interference, diffraction, and light scattering. [1] Compared to pigmented colors, structural colors have many useful properties, including iridescence, high reflectance, and polarization. These optical properties have been applied in many fields such as color displays, decorations, anti-counterfeiting and fluid sensors. [2] Among the many structural color studies, we have examined the optical properties of the porous alumina film formed using Aluminium Anodic Oxidation(AAO). Specifically, their studies were reported that porous thin films formed by AAO processes produces bright colors in the visible range. [3] In addition, fabricated alumina – nickel film by AAO process and electroplating has been reported to exhibit structural color.[2] In this study, to improve the nanostructure color using the metal light scattering effect. Aluminum was deposited by sputtering on the nanocomposite film fabricated by the AAO process and the electroplating process. The AAO process was performed by applying a voltage of 20 V in 0.1 M sulfuric acid electrolyte. The pore diameter of the formed porous alumina was 25 nm, the depth was formed to 600 nm. After the AAO process, nickel thickness of 50","PeriodicalId":276715,"journal":{"name":"Proceedings of the 7th World Congress on Recent Advances in Nanotechnology","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115722815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-supported LDH-decorated Nanotube Networks as 3D Platforms for Electrochemical Applications","authors":"Khaled M. Amin, W. Ensinger","doi":"10.11159/icnnfc22.140","DOIUrl":"https://doi.org/10.11159/icnnfc22.140","url":null,"abstract":"Extended Abstract Different classes of materials are emerging in the recently used catalyst electrode systems. The performance of such electrodes in different electrochemical applications is mainly attributed to the density of active sites and the conductivity of the electrode material. These two parameters can be controlled through the composition of the active material itself and the electrode design. Most of the common electrode systems include the use of assisting electrodes such as glassy carbon and/or a binder which may suppress the electrocatalytic activity. Metal nanotube/wire networks can provide not only a high surface area and efficient electron transport via the 1D nanoscale building blocks but also excellent mass transport and enhanced stability due to the highly porous 3D network, which in turn can improve the electrode performance. Layered double hydroxide (LDH) is one of the efficient redox structures but still suffers from fast agglomeration and limited conductivity, although their high electrocatalytic activity [1]. Herein, we tried tailoring a new architecture gathering the advantageous properties of the metal nanotube/wire networks, including efficient electron conduction paths and high porosity, with those of LDH nanosheets, including high redox-active sites, in an integrated design. In addition, this combination has been supported by a thick electrodeposited metal layer that works as a current collector forming a free-standing electrode system that is suitable for different electrochemical applications. This approach depends on a simple and scalable technique, namely electrodeposition and electroless plating, for the fabrication of a new generation of self-supported electrodes. The as-prepared electrode can be utilized in different electrochemical applications depending on the compositional and geometric requirements of the active material. The good properties offered by that class of electrodes are reflected in the high performance established in different applications such as energy storage, catalysis, and electrochemical sensing. Different LDH nanosheets such as NiCo and NiFe were successfully electrodeposited on a network of interconnected Ni nanotubes of 200 and 400 nm diameter. SEM micrographs and EDX spectra confirmed the loading of the LDH nanosheets over surfaces of Ni and the complete covering of the whole surface with a uniform layer of thin LDH sheets. Cyclic voltammograms revealed the characteristic redox peaks of the included metal hydroxides. The LDH-decorated networks showed enhanced performance as electrodes for supercapacitors and glucose sensing. For instance, The NiCo hydroxide-decorated nanotube networks showed high sensitivity (4.6 mA mM -1 cm -2 ) and a very low detection limit of 0.2 µM which is nearly three times lower than the corresponding value of the pristine Ni nanotube network (~ 0.7 µM) [2]. Meanwhile, it demonstrated high capacity (~120 C cm -3 ) and remarkable rate capability as electrodes f","PeriodicalId":276715,"journal":{"name":"Proceedings of the 7th World Congress on Recent Advances in Nanotechnology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125738126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ion Damage Tracks in Polymers - Fabrication of 1-Dimensional Nanostructures: Nanochannels, Nanowires and Nanotubes","authors":"W. Ensinger","doi":"10.11159/icnnfc22.003","DOIUrl":"https://doi.org/10.11159/icnnfc22.003","url":null,"abstract":"Radiation damage tracks of heavy ions in polymer foils and their chemical etching into nanochannels in combination with (electro)chemical treatment offers a versatile technique for fabrication of 1-dimensionsal nanostructures: functionalized nanochannels, nanowires and nanotubes. When ions of heavy elements with large kinetic energy and a high charge state cross a polymer foil, they set energetic electrons free (delta-electrons) that are able to break covalent chemical bonds. Along the ion trajectories, the polymers show both a reduced density and a lower chemical stability. Here, the polymers can chemically be etched with a large track-to-bulk etch ratio, thus forming high-aspect-ratio nanochannels (ion track etching method). An example is the formation of a 10 nm diameter nanochannel in a 10 micrometer thick polyester foil by irradiation with 2 GeV Au-ions. Polymer films with such nanochannels can act on one hand as a filter or a sensing device and on the other hand they can be used as a exotemplate for fabricating 1-dimensional nanostructures such as nanowires and nanotubes. For this purpose, the nanochannels are homogeneously filled with metals or oxides, either galvanically or redox-chemically. The electrochemical deposition yields solid nanowires, the electroless deposition nanotubes that are obtained by depositing a thin film onto the nanochannel walls. When the template is removed by chemical dissolution, the nanostructures are set free. In the present contribution, the ion damage track formation in the polymer is described and the template technique and its parameters for etching nanochannels are explained. obtained 1-D nanostructures several will be shown: Examples of the application of nanochannels as (bio)chemical sensors after chemically modification by attaching biorecognition molecules will be presented. Typical application fields are medical diagnostics and environmental sensing. In case of the metallic nanowires and nanotubes, applications in (electro)catalysis in microreactors, as fuel cell electrodes and for force/acceleration sensing will be presented.","PeriodicalId":276715,"journal":{"name":"Proceedings of the 7th World Congress on Recent Advances in Nanotechnology","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131503665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biobased Elastomer Nanofibers for Guiding Skeletal Muscle Regeneration","authors":"A. Cheesbrough, I. Lieberam, Wenhui Son","doi":"10.11159/nddte22.134","DOIUrl":"https://doi.org/10.11159/nddte22.134","url":null,"abstract":"Extended Abstract Skeletal muscle is the most abundant tissue in the human body. It is of high clinical importance because of the crucial role it plays in respiration, locomotion, and behaviour. Skeletal muscle is a highly organised tissue composed of aligned muscle fiber bundles, muscle connective tissue, blood vessels and other extracellular structures. Innervation by excitatory motor neurons enables muscle contractions, while support from other tissues such as the tendons, provide anchorage to contractile myofibers. Skeletal muscle can alter its’ structural and functional properties in response to a range of environmental signals, including motor input, exercise, and disease. Genetic, metabolic, and age-related disease can affect its’ regenerative potential, and can lead to debilitating muscle weakness and dysfunction. To fully understand these mechanisms, physiologically and functionally relevant tissue engineered in vitro models are required [1] . Animal models are both cost- and time-intensive, whilst 2D cell culture assays fail to capture the 3D arrangement of cells and surrounding extracellular matrix (ECM) [2]. This project combines nano-engineered elastomer nanofiber sheets with human induced pluripotent stem cell (iPSC) derived myofibers in the establishment of an in vitro model of skeletal muscle function. an co-polymer","PeriodicalId":276715,"journal":{"name":"Proceedings of the 7th World Congress on Recent Advances in Nanotechnology","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132303066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanostructuration In Hydrogels And Electrospun Fibre Mats For\u0000Biomedical Applications","authors":"A. Korsunsky","doi":"10.11159/icnnfc22.001","DOIUrl":"https://doi.org/10.11159/icnnfc22.001","url":null,"abstract":"- The ever increasing demand for technological devices for biomedical use relies crucially on the development and optimisation of materials with specific properties. Two routes considered in the present study concern hydrogel formulations for organ phantoms, and the use of electrospinning to obtain unwoven mats for scaffolding, filtering, etc. The use of dvanced characterisation techniques such as electron microscopy and stynchrotron X-ray scattering will be presented. Procedures for the assessment of the sutiability of new material system for chosen applications will be discussed.","PeriodicalId":276715,"journal":{"name":"Proceedings of the 7th World Congress on Recent Advances in Nanotechnology","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124571098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}