Biosensors and Bioelectronics: X最新文献

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A simple MOF-based nanosensor for bisphenol A detection: in vitro application in supernatant of human endothelial cell models 用于双酚A检测的简单mof纳米传感器:在人内皮细胞模型上清液中的体外应用
IF 10.61
Biosensors and Bioelectronics: X Pub Date : 2025-08-06 DOI: 10.1016/j.biosx.2025.100666
Lorena Garcia-Rodrigo , Cristina Tortolini , Araceli González-Cortés , Ilenia Ventura , Silvia Migliaccio , Elisabetta Ferretti , Riccarda Antiochia
{"title":"A simple MOF-based nanosensor for bisphenol A detection: in vitro application in supernatant of human endothelial cell models","authors":"Lorena Garcia-Rodrigo ,&nbsp;Cristina Tortolini ,&nbsp;Araceli González-Cortés ,&nbsp;Ilenia Ventura ,&nbsp;Silvia Migliaccio ,&nbsp;Elisabetta Ferretti ,&nbsp;Riccarda Antiochia","doi":"10.1016/j.biosx.2025.100666","DOIUrl":"10.1016/j.biosx.2025.100666","url":null,"abstract":"<div><div>This work describes a simple electrochemical nanosensor for bisphenol A (BPA) detection based on an iron metal organic framework (MIL-100(Fe)) immobilized onto a commercial multiwalled carbon nanotubes (MWCNTs)/gold nanoparticles (AuNPs) modified graphite screen printed electrode (GSPE). The electrochemical platform has been characterized by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and SEM-EDX analysis. The resulting MIL-100(Fe)/AuNPs_MWCNTs/GSPE platform exhibited competitive analytical performances, including a wide dynamic range (0.1–100 μM), and a low detection limit (20 nM). Additionally, the proposed sensor demonstrated excellent selectivity, enabling accurate BPA detection in the presence of potential interferences. Lastly, the sensor has been successfully tested for <em>in vitro</em> BPA detection in the supernatant samples of human endothelial cellular models, Human Umbilical Vein Endothelial Cells (HUVECs) and Human Aortic Endothelial Cells (HAECs), exposed to BPA. These findings highlight the potential of the proposed nanosensor for the detection of BPA in supernatant cell fluids of individuals exposed to BPA at different concentrations and incubation times.</div></div>","PeriodicalId":260,"journal":{"name":"Biosensors and Bioelectronics: X","volume":"26 ","pages":"Article 100666"},"PeriodicalIF":10.61,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144827569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A wireless reader for detecting frequency shift of passive sensors 一种用于检测无源传感器频移的无线读取器
IF 10.61
Biosensors and Bioelectronics: X Pub Date : 2025-08-05 DOI: 10.1016/j.biosx.2025.100668
Fariborz Mirlou , Emine Bardakci , Taher Abbasiasl , Levent Beker
{"title":"A wireless reader for detecting frequency shift of passive sensors","authors":"Fariborz Mirlou ,&nbsp;Emine Bardakci ,&nbsp;Taher Abbasiasl ,&nbsp;Levent Beker","doi":"10.1016/j.biosx.2025.100668","DOIUrl":"10.1016/j.biosx.2025.100668","url":null,"abstract":"<div><div>A body area sensor network (bodyNET) consists of wearable and implantable sensors to monitor human physiological signals. While passive disposable, chip-free, and batteryless sensors have been widely studied, benchtop equipment is still required for data collection, limiting usage to laboratory settings. Efficient integration of passive wearable and implantable sensors with dedicated compact readout circuitry is crucial for enabling data acquisition outside controlled laboratory environments. Here, we present a miniaturized, flexible wireless reader (WiRe) designed for frequency-shifting passive sensors, which also incorporates power harvesting capability. WiRe is compatible with a wide variety of passive sensors, offering a versatile platform for diverse medical applications. We deployed WiRe across various passive sensor platforms to track frequency shifts associated with biological signals. Our results show that WiRe uniquely combines power harvesting with a flexible, portable readout interface, enabling effective and non-invasive detection of even minor frequency shifts in a frequency sweep range of 1–8 MHz with 100 kHz resolution for both in vitro and in vivo experiments.</div></div>","PeriodicalId":260,"journal":{"name":"Biosensors and Bioelectronics: X","volume":"26 ","pages":"Article 100668"},"PeriodicalIF":10.61,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144827571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detecting age-related changes in faecal vasoactive intestinal polypeptide using a 3D-printed electrochemical immunosensor 利用3d打印电化学免疫传感器检测粪便血管活性肠多肽的年龄相关变化
IF 10.61
Biosensors and Bioelectronics: X Pub Date : 2025-08-04 DOI: 10.1016/j.biosx.2025.100667
Khalil K. Hussain , Chloe Miller , Mark Yeoman , Bhavik Anil Patel
{"title":"Detecting age-related changes in faecal vasoactive intestinal polypeptide using a 3D-printed electrochemical immunosensor","authors":"Khalil K. Hussain ,&nbsp;Chloe Miller ,&nbsp;Mark Yeoman ,&nbsp;Bhavik Anil Patel","doi":"10.1016/j.biosx.2025.100667","DOIUrl":"10.1016/j.biosx.2025.100667","url":null,"abstract":"<div><div>Vasoactive intestinal polypeptide (VIP) is a 28-amino acid neuropeptide with a multitude of diverse physiological functions, including vasodilation, immune modulation, and most notable gastrointestinal regulation. At present, VIP is determined using biochemical assays, which are time-consuming and require complex multi-step sample preparation. Therefore, we focused on the development of the first electrochemical immunosensor for the detection of VIP in faecal pellets. Our VIP immunosensor was made by covalent immobilization of an anti-VIP antibody onto a thiophene-2-carboxylic acid conductive polymer layer, after deposition of gold nanostars onto a carbon black/polylactic acid 3D printed electrode. Scanning electron microscopy and electrochemical measurements confirmed layer-by-layer modification of the electrode to craft the VIP immunosensor. The immunosensor exhibited a linear range between 10 and 100 pM, with a limit of detection of 4.3 pM. The immunosensor was selective against electroactive compounds known to be present within the intestinal tract. We observed a reduction in VIP levels in faecal pellets from 24-month-old mice when compared to 12-month-old mice. This novel VIP electrochemical immunosensor can be an effective tool for diagnosis or prognosis of various diseases given the diverse physiological function of VIP.</div></div>","PeriodicalId":260,"journal":{"name":"Biosensors and Bioelectronics: X","volume":"26 ","pages":"Article 100667"},"PeriodicalIF":10.61,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144766915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acrylate/GO composite film enabled optical microcavity relative humidity sensor with enhanced sensitivity by pump-detection technique 丙烯酸酯/氧化石墨烯复合膜光学微腔相对湿度传感器通过泵浦检测技术提高了灵敏度
IF 10.61
Biosensors and Bioelectronics: X Pub Date : 2025-07-31 DOI: 10.1016/j.biosx.2025.100665
Senpeng Zhang, Bo Dong, Zhuojun Wang, Ziheng Yu, Yulong Wang
{"title":"Acrylate/GO composite film enabled optical microcavity relative humidity sensor with enhanced sensitivity by pump-detection technique","authors":"Senpeng Zhang,&nbsp;Bo Dong,&nbsp;Zhuojun Wang,&nbsp;Ziheng Yu,&nbsp;Yulong Wang","doi":"10.1016/j.biosx.2025.100665","DOIUrl":"10.1016/j.biosx.2025.100665","url":null,"abstract":"<div><div>An acrylate/graphene oxide (GO) composite film enabled optical microcavity relative humidity (RH) sensor with enhanced sensitivity by pump-detection technique is presented. An acrylate/GO composite film serves as both the sensitive film and reflection film of an open optical microcavity, which is fabricated by 3D printing on the end face of a single-mode fiber. A pump-detection technique is used to improve the sensitivity of the sensor. Experimental results show that its sensitivity is only 151.11 p.m./%RH without the 980-nm pump light. In contrast, its sensitivity is significantly improved after introducing the 980-nm pump light, and its sensitivity reaches 2.4 times as much as that of the unpumped sensor. Moreover, it exhibits fast response characteristics with humidity response time and recovery time of 0.32 s and 1.40 s, respectively. In real-world application tests, the sensor effectively distinguishes normal, rapid, slow, and apnea breathing patterns, demonstrating strong potential for medical and sports-related respiratory monitoring.</div></div>","PeriodicalId":260,"journal":{"name":"Biosensors and Bioelectronics: X","volume":"26 ","pages":"Article 100665"},"PeriodicalIF":10.61,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144763814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fluorescence sensing platform based on graphene oxide nucleic acid interaction for detecting mercury ions, bisphenol A, and target DNA 基于氧化石墨烯核酸相互作用的荧光传感平台,用于检测汞离子、双酚A和靶DNA
IF 10.61
Biosensors and Bioelectronics: X Pub Date : 2025-07-28 DOI: 10.1016/j.biosx.2025.100662
Xiangyu Xu, Yinan Guo, Xiong Zhou, Shuai Xu, Heng Xu
{"title":"Fluorescence sensing platform based on graphene oxide nucleic acid interaction for detecting mercury ions, bisphenol A, and target DNA","authors":"Xiangyu Xu,&nbsp;Yinan Guo,&nbsp;Xiong Zhou,&nbsp;Shuai Xu,&nbsp;Heng Xu","doi":"10.1016/j.biosx.2025.100662","DOIUrl":"10.1016/j.biosx.2025.100662","url":null,"abstract":"<div><div>A multifunctional fluorescence sensing platform based on graphene oxide (GO) was developed to meet the rapid detection needs of environmental pollutants. Three specific mechanisms were employed to achieve highly sensitive detection. One was to use the T-Hg2+ - T structure to induce the dissociation of double stranded DNA from GO surface, achieving Hg2+ detection with a linear range of 100–1500 nM and a detection limit of 0.110 μ M. The second method was to release the trigger chain through the dissociation of bisphenol A (BPA) adapter complementary chain complex, combined with GO fluorescence quenching characteristics to detect BPA, with a detection limit of 0.5035 μ g/mL. The third method used Exo III enzyme to cleave double stranded DNA for signal amplification, combined with GO differential adsorption detection of nucleic acid fragments to detect target DNA, corresponding to a linear range of 0.01–0.4 nM and a detection limit of 11.2 pM. The spiked recovery rates of the three methods in wastewater/serum samples were 96.82 %–107.49 %, with a relative standard deviation of&lt;3.47 %. The above research method combined nucleic acid recognition characteristics with GO signal regulation function through modular design, providing a new strategy for on-site detection of environmental pollutants.</div></div>","PeriodicalId":260,"journal":{"name":"Biosensors and Bioelectronics: X","volume":"26 ","pages":"Article 100662"},"PeriodicalIF":10.61,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144827570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hydrogel-based multiplexed high-risk human papillomavirus DNA/RNA detection for cervical cancer screening 基于水凝胶的多重高危人乳头瘤病毒DNA/RNA检测用于宫颈癌筛查
IF 10.61
Biosensors and Bioelectronics: X Pub Date : 2025-07-28 DOI: 10.1016/j.biosx.2025.100664
Morteza Azizi , Jae-Sang Hong , Joshua Spitzberg , Ralph Weissleder , Cesar M. Castro , Hyungsoon Im
{"title":"Hydrogel-based multiplexed high-risk human papillomavirus DNA/RNA detection for cervical cancer screening","authors":"Morteza Azizi ,&nbsp;Jae-Sang Hong ,&nbsp;Joshua Spitzberg ,&nbsp;Ralph Weissleder ,&nbsp;Cesar M. Castro ,&nbsp;Hyungsoon Im","doi":"10.1016/j.biosx.2025.100664","DOIUrl":"10.1016/j.biosx.2025.100664","url":null,"abstract":"<div><div>Rapid triaging of high-risk human papillomavirus (HPV) infections, especially in resource-limited regions, can reduce cervical cancer deaths by identifying high-risk patients and minimizing pathology bottlenecks and overtreatment. Here, we developed a simple, rapid method for parallel detection of HPV DNA and RNA subtypes associated with a high risk of developing cervical cancer. Specifically, we applied loop-mediated isothermal nucleic acid amplification (LAMP) in a hydrogel-based platform (LAMPGel) for HPV DNA or RNA detection using distinct hydrogel chambers within a single chip. The LAMPGel platform locally restricts single HPV gDNA or mRNA strands with a LAMP cocktail, which is then distributed within a thin hydrogel to locally form single fluorescent spots after a short isothermal incubation of &lt;30 min. Detecting and counting these spots identifies HPV infection, viral load, and, more importantly, RNA expression as a predictive marker for cervical cancer development. LAMPGel is a sensitive, specific, easy-to-use, and rapid method for a point-of-care (POC) platform for potential applications in low- and middle-income countries once the technology is further validated with clinical samples in those settings. Furthermore, it could find broader applications in POC nucleic acid assays.</div></div>","PeriodicalId":260,"journal":{"name":"Biosensors and Bioelectronics: X","volume":"26 ","pages":"Article 100664"},"PeriodicalIF":10.61,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144738870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimization of a portable ligand-free optical spectroscopy method for SARS-CoV-2 protein detection 便携式无配体光学光谱法检测SARS-CoV-2蛋白的优化
IF 10.61
Biosensors and Bioelectronics: X Pub Date : 2025-07-28 DOI: 10.1016/j.biosx.2025.100663
Fatin Hamimi Mustafa , Nik Yusnoraini Yusof , Mawaddah Mohd Azlan , Fariza Hanim Suhailin , Chan Yean Yean , Nik Mohd Noor Nik Zuraina , Mohd Zulkifli Salleh , Hironaga Uchida , Irneza Ismail , Rosline Hassan , Raja Kamarulzaman Raja Ibrahim , Mohd Adzir Mahdi
{"title":"Optimization of a portable ligand-free optical spectroscopy method for SARS-CoV-2 protein detection","authors":"Fatin Hamimi Mustafa ,&nbsp;Nik Yusnoraini Yusof ,&nbsp;Mawaddah Mohd Azlan ,&nbsp;Fariza Hanim Suhailin ,&nbsp;Chan Yean Yean ,&nbsp;Nik Mohd Noor Nik Zuraina ,&nbsp;Mohd Zulkifli Salleh ,&nbsp;Hironaga Uchida ,&nbsp;Irneza Ismail ,&nbsp;Rosline Hassan ,&nbsp;Raja Kamarulzaman Raja Ibrahim ,&nbsp;Mohd Adzir Mahdi","doi":"10.1016/j.biosx.2025.100663","DOIUrl":"10.1016/j.biosx.2025.100663","url":null,"abstract":"<div><div>The rapid spread of COVID-19 has underscored the need for fast, portable, and reliable diagnostic tools. Conventional techniques such as polymerase chain reaction and emerging biosensors like surface plasmon resonance require complex procedures for ligand development and immobilization, which often involve probes, antibodies, or aptamers. This study proposes a ligand-free detection strategy based on optical spectroscopy for the rapid identification of the SARS-CoV-2 protein. The detection workflow includes two key phases: optimization and clinical validation. In the optimization phase, transmittance spectral measurements were conducted on SARS-CoV-2 protein to determine the optimal wavelength within the ultraviolet–visible–near infrared range (200–1100 nm). The most effective fiber configuration was also evaluated using three combinations of transmitter–receiver fiber diameters: 600–400 μm, 600–100 μm, and 200–400 μm. The optimal detection parameters were identified as 275 nm for wavelength and 600–400 μm for fiber configuration. Specificity testing confirmed complete discrimination between SARS-CoV-2 protein and other proteins, including SARS-CoV and rBmSXP, with 100 % specificity. Subsequently, clinical validation was conducted on 21 patients using the optimized parameters. Optical spectroscopy measurements were compared with real-time quantitative reverse transcription polymerase chain reaction (RT-qPCR), yielding a correlation coefficient of 0.6038 with statistical significance (p &lt; 0.01). These findings demonstrate the potential of portable, ligand-free optical spectroscopy for rapid SARS-CoV-2 detection at the point of care.</div></div>","PeriodicalId":260,"journal":{"name":"Biosensors and Bioelectronics: X","volume":"26 ","pages":"Article 100663"},"PeriodicalIF":10.61,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144766914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular imprinting and nanomaterial synergy for lactate detection 乳酸检测的分子印迹和纳米材料协同作用
IF 10.61
Biosensors and Bioelectronics: X Pub Date : 2025-07-25 DOI: 10.1016/j.biosx.2025.100659
Christopher Animashaun , Gymama Slaughter
{"title":"Molecular imprinting and nanomaterial synergy for lactate detection","authors":"Christopher Animashaun ,&nbsp;Gymama Slaughter","doi":"10.1016/j.biosx.2025.100659","DOIUrl":"10.1016/j.biosx.2025.100659","url":null,"abstract":"<div><div>Molecularly imprinted polymer (MIP)-based electrochemical sensors have emerged as promising non-enzymatic platforms for the selective and stable detection of clinically and environmentally relevant biomarkers. This review provides a critical, comprehensive analysis of recent advances in MIP-based lactate sensing, with particular emphasis on hybrid systems that integrate conductive nanomaterials including gold and silver nanoparticles, laser-induced graphene, and reduced graphene oxide. These synergistic combinations leverage enhanced surface area, electrical conductivity, and molecular recognition to improve sensor sensitivity, selectivity, and long-term operational stability. Key fabrication strategies, such as electropolymerization, green nanomaterial synthesis, and surface imprinting, are critically examined for their roles in optimizing imprinting sensitivity and electron transfer efficiency. Application areas span real-time lactate monitoring in wearable health devices to environmental surveillance in complex matrices. Despite significant progress, challenges related to reproducibility, template removal efficiency, fouling resistance, and scalable manufacturing persist. The review concludes by outlining future directions, including integration into flexible and paper-based platforms, and the development of smart, implantable systems. With continued innovation, MIP-based lactate sensors are poised to become essential components in next-generation point-of-care diagnostics and environmental monitoring technologies.</div></div>","PeriodicalId":260,"journal":{"name":"Biosensors and Bioelectronics: X","volume":"26 ","pages":"Article 100659"},"PeriodicalIF":10.61,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144714314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dry-printed carbon nanotube film based electrochemical immunosensor for total testosterone detection 基于干印碳纳米管薄膜的总睾酮检测电化学免疫传感器
IF 10.61
Biosensors and Bioelectronics: X Pub Date : 2025-07-25 DOI: 10.1016/j.biosx.2025.100660
Narender Kumar Joon, Jane Besong-Ndika, Elisa Mikkonen, Ville Rajala, Samuel Dulay, Ilkka Varjos
{"title":"Dry-printed carbon nanotube film based electrochemical immunosensor for total testosterone detection","authors":"Narender Kumar Joon,&nbsp;Jane Besong-Ndika,&nbsp;Elisa Mikkonen,&nbsp;Ville Rajala,&nbsp;Samuel Dulay,&nbsp;Ilkka Varjos","doi":"10.1016/j.biosx.2025.100660","DOIUrl":"10.1016/j.biosx.2025.100660","url":null,"abstract":"<div><div>Testosterone (TST), a critical hormone for male health, requires precise monitoring due to the significant adverse effects of both deficiency and excess, including reproductive dysfunction, mood alterations, and metabolic imbalances. This study reports a novel electrochemical biosensor designed for rapid and sensitive point-of-care (POC) detection of total TST in serum samples. The sensing platform utilizes a cost-effective, roll-to-roll processed carbon nanotube (CNT) film as a scaffold. To create the biorecognition layer, bovine serum albumin-testosterone conjugate (BSA TST) was uniformly immobilized into the CNT film using an automated liquid dispensing system, enabling high-throughput and reproducible sensor fabrication. The biosensor employs a competitive immunoassay principle, where TST in the sample competes with immobilized BSA TST for the binding sites of antibody against TST horse-radish peroxidase conjugate (AbHRP). Amperometry at −0.2 V vs. Ag/AgCl ink was used to monitor affinity reaction upon addition of H<sub>2</sub>O<sub>2</sub> with 3,3′,5,5′-Tetramethylbenzidine (TMB) redox mediator yielding a dynamic range of 82–1080 ng/dL. Limit of detection (LOD) and limit of quantification (LOQ) of 12.7 and 82 ng/dL were achieved respectively. Validation in spiked human serum demonstrated excellent performance, with quantifiable results aligning well with the established physiological range of TST in healthy males (186–1180 ng/dL), highlighting the potential of this biosensor for clinical applications.</div></div>","PeriodicalId":260,"journal":{"name":"Biosensors and Bioelectronics: X","volume":"26 ","pages":"Article 100660"},"PeriodicalIF":10.61,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144721619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advanced analysis of fully-printed organic transistors platform for multi-ion detection in sweat 汗液中多离子检测全印刷有机晶体管平台的先进分析
IF 10.61
Biosensors and Bioelectronics: X Pub Date : 2025-07-25 DOI: 10.1016/j.biosx.2025.100661
Silvia Demuru , Jaemin Kim , Ilya Kiselev , Guillaume Joël Jeanneret-Grosjean , Brince Paul Kunnel , Min Liu , Xi Chen , Mathieu Saubade , Celine Lafaye , Shih-Chii Liu , Danick Briand
{"title":"Advanced analysis of fully-printed organic transistors platform for multi-ion detection in sweat","authors":"Silvia Demuru ,&nbsp;Jaemin Kim ,&nbsp;Ilya Kiselev ,&nbsp;Guillaume Joël Jeanneret-Grosjean ,&nbsp;Brince Paul Kunnel ,&nbsp;Min Liu ,&nbsp;Xi Chen ,&nbsp;Mathieu Saubade ,&nbsp;Celine Lafaye ,&nbsp;Shih-Chii Liu ,&nbsp;Danick Briand","doi":"10.1016/j.biosx.2025.100661","DOIUrl":"10.1016/j.biosx.2025.100661","url":null,"abstract":"","PeriodicalId":260,"journal":{"name":"Biosensors and Bioelectronics: X","volume":"26 ","pages":"Article 100661"},"PeriodicalIF":10.61,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144738873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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