Anna Romolo, M. Hočevar, A. Iglič, T. Griessler Bulc, V. Kralj-Iglič
{"title":"Short Term Effect of Plant Hybridosomes on Growth of Phaeodactylum Tricornutum Culture","authors":"Anna Romolo, M. Hočevar, A. Iglič, T. Griessler Bulc, V. Kralj-Iglič","doi":"10.55295/psl.2023.ii12","DOIUrl":"https://doi.org/10.55295/psl.2023.ii12","url":null,"abstract":"Microalgae are in focus of extensive study due to their abundance and important role in equilibration of the global ecosystem. Living organisms communicate through nano-sized membrane-enclosed particles which are continuously shed by cells but can also be fabri-cated artificially. In this work we examined the effect of hybridosomes composed from soyabean lecithin, aqueous solution containing substances from spruce needles and glyc-erol and hybridosomes composed from soyabean lecithin, ultraclean water and hemp oil on the number density of microalgae Phaeodactylum tricornutum in culture. We measured the number density of microalgae by flow cytometry and the number density and hydro-dynamic diameter of small particles in the samples by interferometric light microscopy. We observed considerable increase of the number density of microalgae with respect to control (untreated) samples after three days, which was connected to the amount of the material added. Addition of membrane-enclosed particles had a favourable effect on the microalgae growth. Microalgae proved a convenient system for in vitro studies of the ef-fects of substances. Keywords: Phaeodactylum tricornutum; Hybridosomes; Liposomes; Nanoalgosomes; Ex-tracellular vesicles; Small cellular particles; Microalgae","PeriodicalId":244164,"journal":{"name":"Socratic Lectures 8","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122672474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful Second Intention Healing of a Large Skin Wound in a Cat's Cheek Using Manuka Honey","authors":"Paul AC Kail","doi":"10.55295/psl.2023.ii7","DOIUrl":"https://doi.org/10.55295/psl.2023.ii7","url":null,"abstract":"A recent case report (Lukanc et al., 2020) demonstrated successful second-intention heal-ing of a large skin wound on a cat’s leg. The wound was treated with honey to kill path-ogens, stimulate the immune response and keep the wound moist. The present case re-port complements this result by showing a similar result in a different part of the body. The subject presented with a burst abscess which left 42-45 square cm of necrotic skin on the side of his cheek. The wound healed over a period of two months through a combina-tion of new skin regeneration and the stretching of existing skin. As a result of this, eu-thanasia was avoided and the patient made a full recovery. The case report details stages in the recovery process and discusses the challenges of protecting the wound while still allowing the patient to experience a reasonable quality of life. Keywords: Skin healing; Second-intention; Manuka honey","PeriodicalId":244164,"journal":{"name":"Socratic Lectures 8","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116748814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interdisciplinary Cooperation and Education at Charité Universitätsmedizin Berlin","authors":"Ema Kocjančič, T. Travnik, B. Kocjančič","doi":"10.55295/psl.2023.ii22","DOIUrl":"https://doi.org/10.55295/psl.2023.ii22","url":null,"abstract":"This report includes the written experience and reflection of a physician and two stu-dents from different faculties of the University of Ljubljana. Within the observatorship programme, we took part at the renowned medical clinic Charité Universitätsmedizin Berlin (Charité). Our stay has familiarised us with several campuses of hospitals and in-stitutions, all taking part of Charité. Within the scope of the observatorship, we got to know several medical professionals from different fields, we were able to observe their work, ethics and their approach to treating patients in outpatient clinics and in intensive care units. Additionally, we were presented with the clinical research conducted by many researchers in Charité’s laboratories. The experience of observing work and re-search at Charité has thus helped broaden our horizons, make new long-lasting interna-tional connections and introduced us to a new, different world of knowledge previously unfamiliar to us. Keywords: Observatorship; Interdisciplinary cooperation; Research; Student; Charité.","PeriodicalId":244164,"journal":{"name":"Socratic Lectures 8","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134530193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sophio Samkharadze, M. Zurmukhtashvili, Eka Kokhreidze, É. Kharashvili, Sesili Beriashvili
{"title":"Availability of Dental Services for Medical Students in Georgia","authors":"Sophio Samkharadze, M. Zurmukhtashvili, Eka Kokhreidze, É. Kharashvili, Sesili Beriashvili","doi":"10.55295/psl.2023.ii5","DOIUrl":"https://doi.org/10.55295/psl.2023.ii5","url":null,"abstract":"Oral health is important issue in field of public health and can be negatively affected by psycho-emotional factors. Foreign medical students can be subjected to oral disease risk factors and therefore be in significant need for regular dental care, but there is a lack of in-formation how good students access the dental clinics. Study aimed to evaluate the acces-sibility to dental care for foreign medical students in Georgia. We conducted an online survey in duration of two weeks in October – November 2022. Study sample were medical undergraduate students, they answered 12 questions about frequency and type of dental visits, about availability and quality of dental care they received in Georgia. Overall from 270 medical undergraduate students aged between 18-45 years, 70% were male and 30% female. 70% were from Jordan, Iran - 15%, Egypt - 4%; Great Britain - 4%, France - 4% and Rwanda - 4%. In their countries 50% of students used to visit dental clinics every 6 months for regular check-up (70%); professional cleaning (31%) and dental pain (27%). 81.48% of interviewed students have never visited a dental clinic in Georgia. Among them who vis-ited, the purpose was check-up (65%) and dental pain (30%). For the source of information about dental clinics the students named internet (60%). Access to dental care was rated as medium (37.50%), while overall satisfaction was rated as normal (47.62%). The study showed very low rate of referral to the dentist. However, among those who visited the clin-ic, their evaluations were satisfactory. We can estimate the lack of information as an im-portant barrier for students. In addition, some students arrived in Georgia only a few months before the study started, so there might be no need to visit dentist in the time inter-val studied. Further research is needed to clearly identify possible barriers for dental care for medical students. Keywords: Oral health; Dental care; Accessibility of dental care; Medical students","PeriodicalId":244164,"journal":{"name":"Socratic Lectures 8","volume":"165 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121302956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Accreditation and Rankings of Universities: Theory of Global Accreditation in the World of (Dis)Order","authors":"Y. Istileulova","doi":"10.55295/psl.2023.ii21","DOIUrl":"https://doi.org/10.55295/psl.2023.ii21","url":null,"abstract":"At the beginning of the third decade, the time of great uncertainties and disorder, higher education institutions re-discovered that accreditation and rankings serve as the visibil-ity mechanisms to attract students, partners and stakeholders. The goal of this paper is threefold: to introduce the Theory of Global Accreditation (TGA) for different organisa-tions (universities, firms, and business schools), to illustrate changes which take place as a result of accreditation practices and to reflect some trends in the market of global edu-cation with different accreditation and ranking schemes. Although the word ‘Accredita-tion’ is used from 1535, the accreditation trends became the new “political” phenomenon in the 21st century. The paper answers the questions: why and how do organisations seek the international accreditations and what are their impacts. The explanation of an observed phenomenon is helpful in a new world disorder filled with crises in multiple fields, and TGA can answer some practical questions of different academic and business organisations as well as different stakeholders as well as facilitate in predicting and grasping the level of expected changes. The examples of accreditation practices are pro-vided for the global business education and in the European Higher Education Area, in line with rankings with the explanation how they become an ‘accelerator’ of higher edu-cation reforms with the growing impact on the landscape of higher education. It is also perceived that international accreditation and rankings agencies can expand their ser-vices becoming the potential areas for consulting, research and science diplomacy in the new world of global disorder. Keywords: Accreditation; Quality Assurance (QA); Rankings; Theory of Global Accredita-tion; Globalisation; Organisational and Institutional Change;","PeriodicalId":244164,"journal":{"name":"Socratic Lectures 8","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114402781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Malidze, R. Bansal, Marina Noniashvili, N. Jojua, T. Gognadze, Mreisa Ahmad
{"title":"Cardiac Arrhythmias in Patients with Myocarditis in the Post-COVID-19 Period","authors":"D. Malidze, R. Bansal, Marina Noniashvili, N. Jojua, T. Gognadze, Mreisa Ahmad","doi":"10.55295/psl.2023.ii1","DOIUrl":"https://doi.org/10.55295/psl.2023.ii1","url":null,"abstract":"To date, several cardiotropic viruses have been implicated as causes of myocarditis. The most detected are parvovirus B19, and human herpes virus 6. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) are the respiratory viruses that have recently triggered the unprecedented pandemic process. The involvement and impact of these viruses in viral cardiovascular disease are under study. Despite extensive research into the pathological mechanisms of viral infections of the cardiovascular system, our knowledge regarding their treatment and management is still incomplete. A condition caused by post- Co rona Virus Disease (COVID-19) myocarditis seems to have distinct inflammatory characteristics. Many kinds of arrhythmias may occur in patients with post-COVID-19 myocarditis and result in arrhythmogenic cardio-myopathy and sudden cardiac death. Sometimes arrhythmia can be the first and only symptom of myocarditis. However, compared to the other clinical presentations, arrhythmic myocarditis has been poorly described in the literature. The increased risk of arrhythmias in patients with a post-COVID-19 period is most likely a consequence of systemic inflammation and diseases, not just a direct consequence of the viral infection. A decrease in heart rate variability can contribute to electrical instability of the myocardium and the occurrence of arrhythmias. Cardiac magnetic resonance imaging and endomyocardial biopsy are the most useful tests for myocarditis. However, different from the other clinical presentations, arrhythmic myocarditis requires specific diagnostic, prognostic, and therapeutic considerations. This review aims to critically summarize the state of the art on myocarditis presenting with arrhythmias in terms of epidemiology, aetiology, diagnosis, prognosis, and treatment. Keywords: Post-COVID-19; SARS-CoV-2; Myocarditis; Arrhythmias; Ferroptosis; Vaccination","PeriodicalId":244164,"journal":{"name":"Socratic Lectures 8","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114617052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Mesoamerican Sound Heritage in Current Argentinian Music for Flute","authors":"Ana Ligia Mastruzzo","doi":"10.55295/psl.2023.ii19","DOIUrl":"https://doi.org/10.55295/psl.2023.ii19","url":null,"abstract":"The theme of the discussion is the influence of Mesoamerican culture legacy in the Argentinian contemporary music for flute. The aim of the article is to analyse the piece ”Coyolyantototl'' (in Náhuatl language meaning place of action of the rattle bird) for Pre columbian flute, flute and recitation in Náhuatl (one performer) composed in 2021 by Federico Núñez and dedicated to Argentinian- Italian flutist Ana Ligia Mastruzzo. Also it was the aim of the article to find the connections between Mesoamerican legacy and the actual musical productions in Latin America. Keywords: Mesoamerican culture; music; Flute; Mexicas; Contemporary music; Prehispanic instrument","PeriodicalId":244164,"journal":{"name":"Socratic Lectures 8","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130182383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aleksandra Štrbac, Janja Ambrožič, Leja Barlič, Nika Berce, Nuša Bolte, Ajla Čoralić, Matija Cingere, Aljaž Černigoj, Amra Dedić, Meta Djura, Tia Fuks, Blaž Georgijev, Urban Gosarič, Mirjam Gril, Maruška Jakše, Neža Japelj, Petra Jesenko, Pia Keber, Klara Klančnik, Uma Kne, Zala Kozjek, Loti Krk, Klara Kuselj, Zoja Lalović, Leon Lazić, Sara Lesjak, John R. Lesnik, Sandra Majcen, Sara Malič, Manca Marenče, Petja Maselj, Alen Mesić, Ajda Mihelič, Anja Miholič, Emina Miljkovic, Kim Modrijan, Lara Moškrič, Anamarija Oprin, Maja Ozmec, Tinkara Pikec, Svit Požgaj, Tijana Prelec, Sara Primožič, Alja Pristov, Raisa Puškar, Nika Sok, Maruša Sovič, Anej Škof, Valentina Šuštarič, Nika Topolovec, Živa Udovč Šink, Taris Vaš, Urška Zupančič, V. Kralj-Iglič
{"title":"Students’ Reflections on 8th Socratic Lectures","authors":"Aleksandra Štrbac, Janja Ambrožič, Leja Barlič, Nika Berce, Nuša Bolte, Ajla Čoralić, Matija Cingere, Aljaž Černigoj, Amra Dedić, Meta Djura, Tia Fuks, Blaž Georgijev, Urban Gosarič, Mirjam Gril, Maruška Jakše, Neža Japelj, Petra Jesenko, Pia Keber, Klara Klančnik, Uma Kne, Zala Kozjek, Loti Krk, Klara Kuselj, Zoja Lalović, Leon Lazić, Sara Lesjak, John R. Lesnik, Sandra Majcen, Sara Malič, Manca Marenče, Petja Maselj, Alen Mesić, Ajda Mihelič, Anja Miholič, Emina Miljkovic, Kim Modrijan, Lara Moškrič, Anamarija Oprin, Maja Ozmec, Tinkara Pikec, Svit Požgaj, Tijana Prelec, Sara Primožič, Alja Pristov, Raisa Puškar, Nika Sok, Maruša Sovič, Anej Škof, Valentina Šuštarič, Nika Topolovec, Živa Udovč Šink, Taris Vaš, Urška Zupančič, V. Kralj-Iglič","doi":"10.55295/psl.2023.ii24","DOIUrl":"https://doi.org/10.55295/psl.2023.ii24","url":null,"abstract":"Symposium Socratic Lectures is primarily devoted to the students. For 15 years, excellent scientists donate their lectures to the students who are the agens movens, for their dedica-tion and interest. The students were actively involved in discussions. Recently developed technologies enabled creation of documents by simultaneous writing in real time during the symposium. In this contribution, the reflections of the students on the content of symposium are given in terms of statements. Keywords: Education; Open book; Social networks","PeriodicalId":244164,"journal":{"name":"Socratic Lectures 8","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129432312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"\"Beethoven in Heiligenstadt in the Museum dedicated to him: the Man and the Artist\"","authors":"R. Schmid, Giancarlo Lamberti","doi":"10.55295/psl.2023.ii23","DOIUrl":"https://doi.org/10.55295/psl.2023.ii23","url":null,"abstract":"The purpose of this contribution is to reflect on the human and musical figure of the great composer Ludwig van Beethoven. In 1802, Beethoven visited Heiligenstadt and in Octo-ber 6 he there wrote his famous \"Testament\" that was found after his death in 1827. The authors have visited the Museum dedicated to Beethoven in Heiligenstadt in the summer of 2022. Keywords: Beethoven; Music; Testament; Heiligenstadt","PeriodicalId":244164,"journal":{"name":"Socratic Lectures 8","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127703714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Extracellular Vesicles for Cosmetic Applications","authors":"Apolonija Bedina Zavec","doi":"10.55295/psl.2023.ii16","DOIUrl":"https://doi.org/10.55295/psl.2023.ii16","url":null,"abstract":"Extracellular vesicles (EVs) are nanosized membrane vesicles that carry membrane and cargo molecules inherited from their parental cells. Excellent delivery capacity, biological origin, and nanosized dimensions support the great potential of EVs as medical and cosmetic active ingredients. Many studies have already reported improved skin conditions by using EVs for skin rejuvenation, scar removal, and anti-pigmentation treatments. In this review, EVs from mesenchymal stem cells, platelets, skin microbiota, and microalgae will be considered. The most promising results come from mesenchymal stem cell (MSC) derived EVs that have impressive antiaging and wound-healing effects on the skin, but their use for medical or cosmetic purposes is not yet allowed in Europe and the United States. Autologous platelet- and extracellular vesicle-rich plasma (PVRP) is well tolerated and capable of rejuvenating the face; intradermal injections and topical applications are currently being considered in clinical and cosmetic dermatology. Symbiotic microorganisms of the human skin have many beneficial effects on the skin, but the presence of bacteria in cosmetic products is restricted; therefore, the preparation of EVs from skin-beneficial microbes is particularly relevant, and there are already many cosmetic products containing lysates from different probiotics on the market. Microalgae can produce many valuable bioactive compounds, antioxidants such as carotenoids are particularly interesting; therefore, microalgae are promising producers of EVs that could be used in cosmetic products. Keywords: Extracellular vesicles; Skin health; Microbiota; Mesenchymal stem cells; Micro-algae","PeriodicalId":244164,"journal":{"name":"Socratic Lectures 8","volume":"137 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121309571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}