Socratic Lectures 8最新文献_第2页

Storage of Platelet-Rich Products 富血小板产品的储存

Socratic Lectures 8 Pub Date : 2023-05-03 DOI: 10.55295/psl.2023.ii3

Kaja Troha, Domen Vozel, S. Battelino

引用次数: 0

Molecular Grammar of RNA-binding Protein Interactions in Formation and Function of Ribonucleoprotein Complexes 核糖核蛋白复合物形成和功能中rna结合蛋白相互作用的分子语法

Socratic Lectures 8 Pub Date : 2023-05-03 DOI: 10.55295/psl.2023.ii15

Maksimiljan Adamek

{"title":"Molecular Grammar of RNA-binding Protein Interactions in Formation and Function of Ribonucleoprotein Complexes","authors":"Maksimiljan Adamek","doi":"10.55295/psl.2023.ii15","DOIUrl":"https://doi.org/10.55295/psl.2023.ii15","url":null,"abstract":"Ribonucleoproteins (RNPs) are macromolecular assemblies of proteins along RNA molecules to carry out specialized cellular processes. Understanding how RNA binding proteins (RBPs) and RNA sequences determine the interactions to form RNPs and ultimately steer biomolecular processes remains poorly understood. There is a mounting evidence that RNP assembly de-pends on the formation of a network of transient, multivalent RBP RNA and RBP RBP interac-tions, particularly between tyrosine residues from intrinsically disordered domains and argi-nine residues from RNA-binding domains of RBPs. Furthermore, RBPs, especially their intrin-sically disordered regions, are hotspots for posttranslational modification (PTM) sites. Alt-hough PTMs have been well catalogued, little is known about how these modifications regulate RNP assembly and function. Some initial studies introduced the concept of the so-called phos-pho-switch, in which RBPs require phosphorylation for condensation of larger RNP complexes, but it remains unclear how this contributes to the protein function and the pattern of selective protein binding to RNA molecules. This short review will take a look at what is currently known in the field of RNPs, their interactions, and the phase-separated biomolecular conden-sates, which are intimately connected to RNPs and are important for several key cell processes. Keywords: Ribonucleoproteins; RNA binding proteins; Multivalency; Intrinsically disordered proteins; Posttranslational modifications","PeriodicalId":244164,"journal":{"name":"Socratic Lectures 8","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129843291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erythrocyte Sedimentation in Tubes for Preparation of Human, Equine and Canine Plasma Rich with Platelets and Extracellular Vesicles 用红细胞沉降管制备人、马和犬富含血小板和细胞外囊泡的血浆

Socratic Lectures 8 Pub Date : 2023-05-03 DOI: 10.55295/psl.2023.ii9

M. Arko, Gitta Schlosse, A. Iglič, P. Kruljc, A. Nemec Svete, V. Erjavec, V. Kralj-Iglič

引用次数: 0

Dielectric Study of Induced Phase Transitions in Lyotropic Liquid Crystals 溶致液晶中诱导相变的介电研究

Socratic Lectures 8 Pub Date : 2023-05-03 DOI: 10.55295/psl.2023.ii13

S. Starzonek, S. Rzoska, A. Iglič

引用次数: 0

Canine Dirofilariasis in the South Caucasus and its Pathomorphology 南高加索犬dirofilaria病及其病理形态学

Socratic Lectures 8 Pub Date : 2023-05-03 DOI: 10.55295/psl.2023.ii8

Levan Tsitskishvili, L. Makaradze, T. Kurashvili, N. Milashvili, Zurab Makaradze, Ekaterina Sanaia

引用次数: 0

Testing Market Efficiency in Emerging Markets’ Stock Indices with Runs Tests 用运行测试检验新兴市场股票指数的市场效率

Socratic Lectures 8 Pub Date : 2023-05-03 DOI: 10.55295/psl.2023.ii17

Nik Smerkolj, M. Jeran

{"title":"Testing Market Efficiency in Emerging Markets’ Stock Indices with Runs Tests","authors":"Nik Smerkolj, M. Jeran","doi":"10.55295/psl.2023.ii17","DOIUrl":"https://doi.org/10.55295/psl.2023.ii17","url":null,"abstract":"According to the efficient market hypothesis (EMH), the prices of securities reflect all the available information on the market. Efficient markets have an important consequence – it is not possible for an investor to consistently outperform the market by using infor-mation that is not already reflected in the prices of securities. No matter how much re-sources one deploys into security analysis, no excess return can be made, which means that investors seeking higher returns must bear higher risk given the risk-return trade-off. Inefficient markets, on the other hand, offer investors opportunities for higher returns at the same risk profile. In this scientific contribution, we test seven emerging markets' stock indices for a weak form of market efficiency. Numerous previous research indicates that emerging markets are not fully efficient and that prices on their stock markets do not fol-low a random walk. We performed runs tests on weekly and monthly returns of stock in-dices and found statistically significant results in three indices for weekly and three in-dices for monthly returns, which indicates that these indices violate weak form of market efficiency. We found insignificant results, which indicate efficient markets, only for weekly and monthly returns on the Indian BSE Sensex 30 Index. Thus we come to similar conclusions as other authors that emerging markets persist to violate weak form of mar-ket efficiency and remain an attractive opportunity for investors seeking to exploit ineffi-ciencies. Keywords: Market efficiency; Efficient market hypothesis; Random walk; Emerging mar-kets; Stock Exchange Index; Runs test","PeriodicalId":244164,"journal":{"name":"Socratic Lectures 8","volume":"228 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130825848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pathogen-Plant Interactions in Plant Membrane Perforation 植物膜穿孔中病原体与植物的相互作用

Socratic Lectures 8 Pub Date : 2023-05-03 DOI: 10.55295/psl.2023.ii14

Andreja Prešern

{"title":"Pathogen-Plant Interactions in Plant Membrane Perforation","authors":"Andreja Prešern","doi":"10.55295/psl.2023.ii14","DOIUrl":"https://doi.org/10.55295/psl.2023.ii14","url":null,"abstract":"Plants are targets of many pathogens that produce a lot of different effectors to damage plant cells during infection. For plant survival, it is, therefore, crucial to possess an effi-cient immune system, which in contrast to mammalian immunity, consists only of in-nate immunity. Traditionally, plant immunity is divided into two branches, i.e. pat-tern-triggered (PTI) and effector-triggered immunity (ETI), but the accumulating knowledge has shown that the division cannot be strictly maintained. ETI coevolves with pathogen e fector molecules, which can function in many different ways to escape plant immunity and damage plant cells. Among their targets is the plant plasma membrane, which repre-sents an important cell barrier. There are several different tactics to bypass this barrier, e.g. membrane perforation by proteins or peptides, which is an important and ubiqui-tously found mechanism of toxicity as well as self-defense in all kingdoms of life. It can be used to get specific molecules from cells, for signaling, or even to deliver effector mol-ecules into the cytoplasm. The exact knowledge on plant membrane perforation, howev-er, is lacking, and the hidden details still await to be unveiled. Keywords: Plant immune System; Pathogen-Plant Interactions; Plant Membrane Perfora-tion","PeriodicalId":244164,"journal":{"name":"Socratic Lectures 8","volume":"144 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127938741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of Oral Health Status among Medical Students in Georgia 乔治亚州医学生口腔健康状况评估

Socratic Lectures 8 Pub Date : 2023-05-03 DOI: 10.55295/psl.2023.ii4

Sophio Samkharadze, M. Zurmukhtashvili, Eka Kokhreidze, É. Kharashvili, Sesili Beriashvili

{"title":"Assessment of Oral Health Status among Medical Students in Georgia","authors":"Sophio Samkharadze, M. Zurmukhtashvili, Eka Kokhreidze, É. Kharashvili, Sesili Beriashvili","doi":"10.55295/psl.2023.ii4","DOIUrl":"https://doi.org/10.55295/psl.2023.ii4","url":null,"abstract":"Oral health is considered as important part of general health. Dental caries and periodon-tal diseases are among most prevalent diseases worldwide. According to WHO oral dis-eases affect nearly 3.5 billion people and untreated dental caries is the most common health condition. Young adults may neglect oral health. The aim of our study was to eval-uate oral health status (dental caries and periodontal diseases) among medical students at European University affiliated dental clinics in Georgia. Simple random sampling method was used. Assessment was conducted using modified WHO Oral Health Assessment Form (2013). Study sample were medical undergraduate students aged between 17 and 25 years at the European University - affiliated dental clinics, Tbilisi, Georgia. Level of dental caries was evaluated by assessment of decayed, missing, and filled teeth scores (DMFT in-dex), while periodontal status was assessed using Community Periodontal Index (CPI) modified index. Statistical analysis of data was performed. Results: Totally 225 students (150 males and 75 females) originally from Georgia, Jordan, Iran, Egypt, Great Britain and Sweden were included in the study. Mean age of participants was 20.7 years. Mean DMFT score in males was 3.11 and in females it was 3.25; overall mean DMFT was 3.18. Percentage of all individuals in two groups with dental caries (DFT ≥ 1) was 84%. Mean CPI index was 0.82 in males and 0.75 in females. Mean DMFT were compared to National estimates for DMFT index for same age group in developed coun-tries. Conclusion: Study showed medium prevalence of caries and low prevalence of periodontal diseases in participant students. Keywords: Oral health, DMFT index, CPI index","PeriodicalId":244164,"journal":{"name":"Socratic Lectures 8","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130120248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electronic Blood Sedimentation Monitoring with Microcontroller and Linear CCD Sensor 基于微控制器和线阵CCD传感器的电子血沉监测

Socratic Lectures 8 Pub Date : 2023-05-03 DOI: 10.55295/psl.2023.ii11

S. Penič, A. Iglič, V. Kralj-Iglič

引用次数: 0

Effects of Capacitive and Resistive Electric Transfer Therapy on Skin Temperature - Literature Review 电容性和电阻性电转移治疗对皮肤温度的影响-文献综述

Socratic Lectures 8 Pub Date : 2023-05-03 DOI: 10.55295/psl.2023.ii10

Serge Bec, Daša Weber, R. Vauhnik

引用次数: 0