Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko最新文献_第8页

[Correction of the effect of vitamin K antagonists and antiplatelet agents in hemorrhagic stroke]. [修正维生素K拮抗剂和抗血小板药物在出血性中风中的作用]。

Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro202488061103

A I Baranich, A A Sychev, I A Savin, V G Kudrina, A V Kozlov

{"title":"[Correction of the effect of vitamin K antagonists and antiplatelet agents in hemorrhagic stroke].","authors":"A I Baranich, A A Sychev, I A Savin, V G Kudrina, A V Kozlov","doi":"10.17116/neiro202488061103","DOIUrl":"10.17116/neiro202488061103","url":null,"abstract":"Background: Hemorrhagic stroke (HS) is associated with high risk of mortality or disability. To date, up to 25% of HSs are associated with anticoagulants and antiplatelet agents. Early hemostatic therapy and correction of effect of antithrombotic drugs in patients with HS significantly reduce the risk of adverse outcomes. The latest international guidelines on this issue were presented almost 10 years ago.Material and methods: In accordance with the PRISMA recommendations, we reviewed the PubMed, eLibrary and UpToDate databases and identified 137 articles. Of these, 52 were enrolled as the most relevant.Results and discussion: Regarding correction of the effect of indirect anticoagulants, various researchers discuss the possibility of either individual dosing or injection of a fixed dose of 4- or 3-factor prothrombin complex (1000-2000 IU regardless of body weight and international normalized ratio). To correct the effect of antiplatelet agents, platelet transfusion and desmopressin are proposed. There is currently no evidence of safety and effectiveness of both methods in patients with HS.Conclusion: The optimal drug for correction of the effect of indirect anticoagulants is 4- or 3-factor prothrombin complex. In the last case, it is necessary to administer factor VIIa or fresh frozen plasma, as well as parenteral form of phytomenadione (vitamin K1) in all cases. The issue of correction of the effects of antiplatelet agents remains open. Regular analysis of available data with updating the guidelines for correction of the effect of anticoagulants and antiplatelet agents in HS is necessary.","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 6","pages":"103-109"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Liquid biopsy in diagnosis of central nervous system tumors]. 【液体活检在中枢神经系统肿瘤诊断中的应用】。

Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro202488061110

A V Gavryushin, A A Veselkov, E A Khukhlaeva, A N Konovalov, A E Druy

{"title":"[Liquid biopsy in diagnosis of central nervous system tumors].","authors":"A V Gavryushin, A A Veselkov, E A Khukhlaeva, A N Konovalov, A E Druy","doi":"10.17116/neiro202488061110","DOIUrl":"https://doi.org/10.17116/neiro202488061110","url":null,"abstract":"Tumor tissue samples are necessary for histological diagnosis. Biopsy is associated with certain difficulties, especially in neuro-oncology. An alternative approach (liquid biopsy) is currently being developed. The last one is based on analysis of biological fluids regarding DNA of tumors and other biomarkers. This less invasive diagnostic method may be valuable to overcome the disadvantages of traditional biopsy.Objective: To analyze available literature data on potential benefits and disadvantages of liquid biopsy.Material and methods: We reviewed the PubMed database throughout the last 18 years.Results: The main targets for liquid biopsy are circulating tumor cells, extracellular vesicles, free circulating DNA and tumor microRNA. Analysis of these biomarkers is perspective for diagnostics and assessment of diseases in neuro-oncology. However, this technique is still poorly understood and has limitations. Therefore, further research is required to explore its capabilities for wider use in clinical practice.Conclusion: Tissue and liquid biopsy can improve the accuracy of diagnosis, assessment of prognosis and effectiveness of treatment of CNS tumors.","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 6","pages":"110-117"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Supratentorial neuroepithelial tumor with PLAGL1 gene fusion - a new type of morphologically variable pediatric brain neoplasm defined by a distinct DNA methylation class. A case report and literature review]. [伴有 PLAGL1 基因融合的脑室上神经上皮性肿瘤--一种由独特 DNA 甲基化类别定义的形态多变的新型小儿脑肿瘤。病例报告和文献综述]。

Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro20248802162

D N Kopachev, M V Ryzhova, A N Kislyakov, E G Shaikhaev, O G Zheludkova, E V Kumirova, S V Meshcheryakov, P A Vlasov, A M Shkatova, Zh B Semenova, A O Gushcha

{"title":"[Supratentorial neuroepithelial tumor with PLAGL1 gene fusion - a new type of morphologically variable pediatric brain neoplasm defined by a distinct DNA methylation class. A case report and literature review].","authors":"D N Kopachev, M V Ryzhova, A N Kislyakov, E G Shaikhaev, O G Zheludkova, E V Kumirova, S V Meshcheryakov, P A Vlasov, A M Shkatova, Zh B Semenova, A O Gushcha","doi":"10.17116/neiro20248802162","DOIUrl":"10.17116/neiro20248802162","url":null,"abstract":"Background: Methylation analysis has become a powerful diagnostic tool in modern neurooncology. This technique is valuable to diagnose new brain tumor types.Objective: To describe the MRI and histological pattern of neuroepithelial tumor with PLAGL1 gene fusion.Material and methods: We present a 6-year-old patient with small right frontal intraaxial tumor causing drug resistant epilepsy. Despite indolent preoperative clinical course and MRI features suggesting glioneuronal tumor, histological evaluation revealed characteristics of high-grade glioma, ependymoma and neuroblastoma.Results: Methylation analysis of tumor DNA confirmed a new type of a recently discovered neoplasm - neuroepithelial tumor with PLAGL1 fusion (NET PLAGL1). PCR confirmed fusion of PLAGL1 and EWSR1 genes. No seizures were observed throughout the follow-up period. There was no tumor relapse a year after surgery.Conclusion: Methylation analysis in neurooncology is essential for unclear tumor morphology or divergence between histological and clinical data. In our case, this technique confirmed benign nature of tumor, and we preferred follow-up without unnecessary adjuvant treatment.","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 2","pages":"62-68"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Disseminated ependymal dysembryoplastic neuroepithelial tumor: a case report and literature review]. [播散性上胚乳发育不良性神经上皮肿瘤：病例报告和文献综述]。

Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro20248804192

Yu V Kushel, M A Kutin, V V Ivanov, I V Chernov, D Sh Adueva, I N Pronin, L V Shishkina, E S Konovalova, P L Kalinin

{"title":"[Disseminated ependymal dysembryoplastic neuroepithelial tumor: a case report and literature review].","authors":"Yu V Kushel, M A Kutin, V V Ivanov, I V Chernov, D Sh Adueva, I N Pronin, L V Shishkina, E S Konovalova, P L Kalinin","doi":"10.17116/neiro20248804192","DOIUrl":"10.17116/neiro20248804192","url":null,"abstract":"Dysembryoplastic neuroepithelial tumor (DNET) is a benign mixed neuronal-glial neoplasm (WHO grade 1). DNET is most often localized in temporal lobes and found in children and young people with epilepsy. There a few cases of DNET in ventricular system with dissemination along the ependyma in the world literature.Material and methods: We present a rare case of T1- and T2-negative ventricular system tumor. Only FIESTA imaging revealed dissemination with multiple focal lesions of the third ventricle, its bottom and lateral walls, anterior horns of lateral ventricles, cerebellar vermis, cervical and lumbar spinal cord.Results: The patient underwent transcortical endoscopic biopsy of the third ventricle tumor with simultaneous ventriculoperitoneal shunting. DNET was diagnosed, and radiotherapy was subsequently performed. Literature data on this issue were analyzed.Conclusion: To date, disseminated forms of DNET are extremely rare. X-ray features and morphological results allow us to establish the correct diagnosis and determine further treatment strategy.","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 4","pages":"92-99"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Puncture dilatation tracheostomy in children during transoral neurosurgical interventions]. [儿童经口神经外科手术中的穿刺扩张气管造口术]。

Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro20248804171

E P Ananyev, A A Sychev, A A Pashin, A N Shkarubo, I A Savin, A S Goryachev

{"title":"[Puncture dilatation tracheostomy in children during transoral neurosurgical interventions].","authors":"E P Ananyev, A A Sychev, A A Pashin, A N Shkarubo, I A Savin, A S Goryachev","doi":"10.17116/neiro20248804171","DOIUrl":"10.17116/neiro20248804171","url":null,"abstract":"Neurosurgical interventions within the ventral surface of the clivus and upper cervical vertebrae in childhood are sometimes carried out through transoral approach. In this situation, tracheostomy is safer for airway protection and mechanical ventilation compared to prolonged intubation. The world experience of percutaneous dilation tracheostomy in pediatric patients is limited due to anatomical and physiological features, such as difficult orientation in anatomical landmarks, high mobility of the trachea and small tracheal lumen. Also, the trachea easily collapses when pressed in pediatric patients that complicates safe puncture of anterior wall and can lead to perforation of posterior tracheal wall.Objective: To describe a modified technique of video-assisted percutaneous dilation tracheostomy using additional thin guide and dilator in children of primary school age.Material and methods: We considered 11 patients aged 6-12 years who underwent video-assisted percutaneous dilation tracheostomy.Results: There were no perioperative complications (bleeding, false course, perforation of posterior tracheal wall). Infection of tracheostomy, fistulas or tracheal stenosis was absent.Conclusion: Percutaneous dilation tracheostomy may be alternative to classical surgical tracheostomy for pediatric patients. Endoscopic control and certain technical changes of percutaneous tracheostomy are necessary and provide safe manipulation. Surgery time, less trauma and minimal cosmetic defect after tracheostomy are significant advantages of this technique compared to surgical tracheostomy.","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 4","pages":"71-77"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Stereotactic high-dose irradiation for intramedullary metastases]. [立体定向高剂量照射治疗髓内转移瘤]。

Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro20248804122

Ya E Goncharov, I S Zubatkina, P I Ivanov

{"title":"[Stereotactic high-dose irradiation for intramedullary metastases].","authors":"Ya E Goncharov, I S Zubatkina, P I Ivanov","doi":"10.17116/neiro20248804122","DOIUrl":"10.17116/neiro20248804122","url":null,"abstract":"Intramedullary metastases (IMM) lead to severe neurological symptoms. They are extremely rare in clinical practice. Optimal management of such patients is not clearly defined. Surgery, chemo- and radiotherapy are the main options.Objective: To study the results of stereotactic high-dose irradiation for IMM considering local control of metastases, neurological status and life expectancy.Material and methods: Nineteen patients with 29 IMMs underwent high-dose irradiation (Cyber Knife G4 and TrueBeam STx devices) between 2016 and 2022. There were 1-10 fractions, radiation dose 14.0-35.0 Gy with isodose 70-100%. Local control and new spinal cord metastases were assessed using contrast-enhanced MRI. Clinical status and neurological functions were assessed using the Karnofsky and McCormick scales.Results: Local control rates were 91% and 78% after 6 and 12 months, respectively. Overall survival after treatment was 7.3 months, 6- and 12-month overall survival - 58% and 37%, respectively. In addition, 8 patients were available for follow-up. Of these, 6 ones demonstrated improvement or stabilization of neurological function after treatment. The main cause of death was progression of the underlying disease. No significant treatment-related toxic effects were observed.Conclusion: High-dose irradiation is a safe, effective and time-saving treatment for IMM. Considering unadvisable surgical methods and chemotherapy for this pathology, we can recommend high-dose irradiation for patients with spinal cord metastases.","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 4","pages":"22-30"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Disease-free survival after surgical and combined treatment of newly diagnosed craniopharyngiomas in adults]. [成人新确诊颅咽管瘤手术和联合治疗后的无病生存率]。

Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro20248805154

M A Kutin, P L Kalinin, A V Golanov, D V Fomichev, Yu Yu Trunin, A N Savateev, Yu V Strunina, I S Klochkova, V V Ivanov, A N Konovalov

{"title":"[Disease-free survival after surgical and combined treatment of newly diagnosed craniopharyngiomas in adults].","authors":"M A Kutin, P L Kalinin, A V Golanov, D V Fomichev, Yu Yu Trunin, A N Savateev, Yu V Strunina, I S Klochkova, V V Ivanov, A N Konovalov","doi":"10.17116/neiro20248805154","DOIUrl":"https://doi.org/10.17116/neiro20248805154","url":null,"abstract":"Craniopharyngioma (CP) is a benign epithelial tumor predominantly localized in chiasmatic-sellar region and third ventricle. There are two histological variants of CP: adamantinoma-like (ACP, 85%) and papillomatous (PCP). These types differ significantly in origin and histological structure. PCP predominantly occurs in adults. Treatment of CP, including effectiveness of radiotherapy, is described in multiple studies and mainly devoted to pediatric patients.Objective: To clarify disease-free survival in adults with newly diagnosed CP depending on resection quality; to evaluate the effectiveness of stereotactic irradiation and treatment depending on histological characteristics of tumor.Material and methods: We analyzed treatment outcomes in 398 adults over 10-year follow-up. Stereotactic irradiation was performed in 11.6% of patients. The follow-up data were obtained in 68.1% of patients. We compared 5-year disease-free survival rates after different resections with and without subsequent irradiation.Results: Total resection is effective and provides significantly lower risk of CP recurrence. Effectiveness of stereotactic irradiation after incomplete resection was also confirmed.Conclusion: Total resection of ACP and PCP provides high disease-free survival rates. Stereotactic irradiation after incomplete resection is followed by similar outcomes. PCPs are characterized by less aggressive growth and do not recur after total resection.","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 5","pages":"54-59"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Dysphagia as the main symptom in anterior cervical spine osteophytes (Forestier disease and cervical spondylosis deformans). Case reports and literature review]. [吞咽困难是颈椎前部骨质增生（Forestier 病和颈椎变形症）的主要症状。病例报告和文献综述]。

Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro20248802169

A V Trashin, N V Vikherev, E M Belov, V A Shamanin, V V Stepanenko

引用次数: 0

[Primary tumors of the brain stem. State of the problem]. [脑干原发性肿瘤：问题现状]。

Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro20248802198

A V Gavryushin, E A Khukhlaeva, A A Veselkov, I N Pronin, A N Konovalov

引用次数: 0

[Intrathecal baclofen therapy: a 30-year experience]. [鞘内巴氯芬疗法：30 年的经验]。

Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro20248803196

I N Morozov, K V Nesterin

{"title":"[Intrathecal baclofen therapy: a 30-year experience].","authors":"I N Morozov, K V Nesterin","doi":"10.17116/neiro20248803196","DOIUrl":"https://doi.org/10.17116/neiro20248803196","url":null,"abstract":"Background: The first pump for intrathecal administration of baclofen was implanted in 1984. Over thirty years, intrathecal prolonged infusion of muscle relaxants has occupied a worthy niche among all methods for correction of non-focal drug-resistant disabling muscle spasticity. However, this method has not become routine despite high awareness of specialists in Russia and abroad, as well as undeniable advantages for restoring the daily activity, improving the walking pattern and providing care and quality of life in people with limited mobility. This is due to scrupulous analysis of adverse events and accurate attitude towards its use.The purpose of this review was to systematize data on indications, selection criteria, pump implantation technique, subsequent patient management and treatment outcomes over a 30-year history.Method: A review of national and foreign literature was performed.Results and conclusion: Prolonged intrathecal baclofen therapy is perspective for long-term treatment of severe spasticity interfering with quality of life and self-care if oral muscle relaxants are contraindicated or ineffective. This procedure is effective for impaired articulation, chewing and spastic pain syndrome. One can reduce the incidence of side effects via correct dosage of the drug, and tolerance to therapy can be reduced by timely elimination of problems with catheter.","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 3","pages":"96-102"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141331881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0