Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko最新文献

筛选
英文 中文
[Transoral approach in surgery for chordomas extending into craniovertebral junction: a systematic review of the literature]. [经口手术治疗延伸至颅椎交界处的脊索瘤:文献系统回顾]。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro202488031111
I V Chernov, A N Shkarubo, D A Konyashin, D N Andreev
{"title":"[Transoral approach in surgery for chordomas extending into craniovertebral junction: a systematic review of the literature].","authors":"I V Chernov, A N Shkarubo, D A Konyashin, D N Andreev","doi":"10.17116/neiro202488031111","DOIUrl":"https://doi.org/10.17116/neiro202488031111","url":null,"abstract":"<p><p>To date, treatment of chordomas involves maximal tumor resection followed by proton therapy. Various approaches are used depending on location of tumor (transcranial and through natural anatomical openings (nose, mouth), as well as their combinations). Although transoral approach has been introduced into neurosurgical practice for a long time, it is routinely used in patients with chordoma only in certain hospitals in the world.</p><p><strong>Objective: </strong>To analyze postoperative outcomes in patients with chordomas of skull base and craniovertebral joint after transoral surgery.</p><p><strong>Material and methods: </strong>We analyzed literature data devoted to patients with chordomas of skull base and craniovertebral joint after transoral surgery or another approach combined with transoral access. Among 111 primary articles, we selected 38 manuscripts including description of 109 patients with skull base chordoma who underwent transoral surgery or combination of approaches including transoral one.</p><p><strong>Results: </strong>Gross total resection was achieved in 45.9% (<i>n</i>=50) of cases including 1 patient after en bloc resection. Subtotal resection was carried out in 28.4% of cases, partial - in 24.8%, biopsy - in 0.9% of cases. The complication rate in this group was 30%. The most common events were swelling of the tongue (10%) and diastasis of posterior pharyngeal wall sutures (8.2%) that required redo surgery. CSF leakage and meningitis were rare (1.8% and 3.6%, respectively).</p><p><strong>Conclusion: </strong>Transoral access allows for gross total resection of midline tumors with low incidence of severe complications. Combination of transoral and transcranial approaches is advisable to increase extent of resection.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 3","pages":"111-119"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141331888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Comparison of polymethyl methacrylate skull implant fixation by three types of titanium fasteners]. [用三种钛紧固件固定聚甲基丙烯酸甲酯颅骨植入体的比较]。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro20248802123
D N Okishev, An N Konovalov, A A Artemyev, E A Okisheva, Yu V Pilipenko, Sh Sh Eliava
{"title":"[Comparison of polymethyl methacrylate skull implant fixation by three types of titanium fasteners].","authors":"D N Okishev, An N Konovalov, A A Artemyev, E A Okisheva, Yu V Pilipenko, Sh Sh Eliava","doi":"10.17116/neiro20248802123","DOIUrl":"10.17116/neiro20248802123","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate mechanical strength of three methods of polymethyl methacrylate skull implant fixation in two experimental models.</p><p><strong>Material and methods: </strong>The first experiment was performed on a plastic model that was as close as possible to bone in structural characteristics. The second experiment was performed on a biological specimen (a ram's head). We assessed the quality of implant fixation to bone window edges by craniofixes, ties and microscrews and lateral intercortical screws.</p><p><strong>Results: </strong>Craniofixes are feasible for small flat flaps, but not advisable for wide highly curved implants. They are also the most expensive method of fixation. Implant fixation by ties and microscrews is a universal method comparable in price to craniofix. Lateral intercortical fixation is effective both for small flat implants and wide implants with large curvature. However, this method is not always applicable.</p><p><strong>Conclusion: </strong>Combined fixation by lateral intercortical screws and ties allows for the most effective fixation while reducing the overall price of consumables.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 2","pages":"23-30"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Convexity hyperostotic meningioma en plaque: a systematic review]. [凸面增生性脑膜瘤:系统回顾]。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro202488011103
K V Efremov, A V Kozlov, S V Tanyashin, K A Kuldashev, R V Zabolotny
{"title":"[Convexity hyperostotic meningioma en plaque: a systematic review].","authors":"K V Efremov, A V Kozlov, S V Tanyashin, K A Kuldashev, R V Zabolotny","doi":"10.17116/neiro202488011103","DOIUrl":"10.17116/neiro202488011103","url":null,"abstract":"<p><strong>Background: </strong>Planar hyperostotic meningiomas account for 2-9% of intracranial meningiomas. They are characterized by planar node following the contours of the inner surface of the skull. Hyperostosis is present in most cases. Timely diagnosis of skull base tumors is usually simple due to early involvement of the cranial nerves. However, convexity meningiomas en plaque usually reach large dimensions that complicates surgery and radiotherapy.</p><p><strong>Objective: </strong>To analyze the current state of diagnosis, molecular biology and surgical treatment of hyperostotic meningiomas en plaque.</p><p><strong>Material and methods: </strong>A systematic review was performed in accordance with the PRISMA guidelines. Searching for literature data included the following keywords: «planar meningioma», «hyperostotic meningioma», «meningioma en plaque», «infiltrative meningioma». We reviewed the PubMed and Google Scholar databases until May 2023 and enrolled only full-text Russian-, English- or French-language reports.</p><p><strong>Results and discussion: </strong>Among primary 332 reports, 35 references met the inclusion criteria. We found less severity or absence of focal neurological symptoms, comparable incidence of intracranial hypertension and no histological differences between planar and nodular meningiomas. Analysis of molecular biological features of planar meningiomas, including cell cultures, is feasible. There is no consensus regarding surgical treatment and radiotherapy. Most publications are case reports.</p><p><strong>Conclusion: </strong>The results of treatment of planar hyperostotic meningiomas, especially large and giant ones, are unsatisfactory. There is no a generally accepted algorithm for treating patients in the literature. This problem requires further research.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 1","pages":"103-108"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Intracardiac migration of a ventriculoperitoneal shunt. A systematic literature review and case report]. 心室腹腔分流术的心内迁移。系统的文献综述和病例报告]。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro20248806188
A V Stanishevskiy, M A Legzdain, N R Saburov, D V Svistov, G V Gavrilov
{"title":"[Intracardiac migration of a ventriculoperitoneal shunt. A systematic literature review and case report].","authors":"A V Stanishevskiy, M A Legzdain, N R Saburov, D V Svistov, G V Gavrilov","doi":"10.17116/neiro20248806188","DOIUrl":"10.17116/neiro20248806188","url":null,"abstract":"<p><p>CSF shunting procedures are common in neurosurgery. A rare complication of these procedures is migration of distal catheter. We present a case of peritoneal catheter migration into the right heart chambers. A systematic review of appropriate literature data was carried out.</p><p><strong>Material and methods: </strong>We present a patient with communicating hydrocephalus after previous penetrating traumatic brain injury. Migration of peritoneal catheter into the right heart chambers occurred in 5 days after ventriculoperitoneal shunting. We performed a systematic review of literature data and analyzed all similar cases of intracardiac migration of ventriculoperitoneal catheter, risk factors of migration, possible complications and surgical treatments.</p><p><strong>Results: </strong>There were 38 articles describing 40 cases of distal catheter migration into the right heart chambers meeting the inclusion criteria. In 65% of patients, catheter migration was diagnosed after ≥2 months. Migration was asymptomatic in 21% of cases. Additionally, less than 50% of patients had no complications. Surgical treatment required complex techniques such as endovascular removal or thoracotomy in nearly 50% of cases.</p><p><strong>Conclusion: </strong>Migration of ventriculoperitoneal catheter into the right heart chambers is a rare and dangerous complication of CSF shunting procedures. Risk factors of this complication should be considered when scheduling surgical treatment and follow-up examinations.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 6","pages":"88-96"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Prospective assessment of surgical stress response in patients with craniosynostosis: comparison of clinical and laboratory data]. [颅骨发育不良患者手术应激反应的前瞻性评估:临床和实验室数据的比较]。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro20248804162
B A Bashiryan, O A Gadzhieva, L A Satanin, N A Mazerkina, E A Khukhlaeva, E A Lavrenyuk, V A Tere, O K Kwan, V V Roginsky
{"title":"[Prospective assessment of surgical stress response in patients with craniosynostosis: comparison of clinical and laboratory data].","authors":"B A Bashiryan, O A Gadzhieva, L A Satanin, N A Mazerkina, E A Khukhlaeva, E A Lavrenyuk, V A Tere, O K Kwan, V V Roginsky","doi":"10.17116/neiro20248804162","DOIUrl":"10.17116/neiro20248804162","url":null,"abstract":"<p><strong>Background: </strong>Highly traumatic surgical correction of craniosynostosis (CS) is usually followed by severe postoperative period and high risk of complications. Surgical stress response (SSR) is an important and often neglected cause of severe early postoperative period.</p><p><strong>Objective: </strong>To compare clinical and laboratory parameters of SSR in children who underwent various surgeries for CS.</p><p><strong>Material and methods: </strong>The study included 63 patients aged 7.02±4.12 months. All ones underwent surgery for CS between October 2021 and June 2022. We analyzed clinical and laboratory markers of SSR, as well as correlation with severity of surgical stress.</p><p><strong>Results: </strong>No surgical complications were observed. There were postoperative complications in 12 (19.0%) cases including febrile fever in 9 (14.3%) patients, severe pain and edematous syndromes with prolonged hospital-stay in 3 (4.8%) cases. Significant correlations were revealed between severity of surgical stress and certain laboratory markers (CRP, ACTH, T3, insulin, HOMA-IR). The last ones characterized SSR severity. Patients with high scores of stress response demonstrated more severe course of early postoperative period.</p><p><strong>Conclusion: </strong>Surgical stress scale makes it possible to predict early postoperative period and optimize patient management. Lower severity of surgical stress response following endoscopic interventions is another reason for the wider use of low-traumatic surgical methods in pediatric neurosurgery.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 4","pages":"62-70"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Microsurgical ventriculostomy of the third ventricle with access through a burrhole in the treatment of midly located deep-seated brain tumors]. [通过毛细孔进入第三脑室的显微外科脑室造口术治疗位置偏中的深部脑肿瘤]。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro2024880215
D I Pitskhelauri, N S Grachev, E S Kudieva, A Z Sanikidze
{"title":"[Microsurgical ventriculostomy of the third ventricle with access through a burrhole in the treatment of midly located deep-seated brain tumors].","authors":"D I Pitskhelauri, N S Grachev, E S Kudieva, A Z Sanikidze","doi":"10.17116/neiro2024880215","DOIUrl":"10.17116/neiro2024880215","url":null,"abstract":"<p><strong>Background: </strong>Currently, endoscopic third ventriculostomy and simultaneous biopsy of deep midline brain tumors are a generally accepted option in neurooncology. Nevertheless, effectiveness of this surgery and diagnostic accuracy of biopsy are not without drawbacks. An alternative to endoscopic surgery may be simultaneous microsurgical third ventriculostomy and biopsy of deep midline tumors.</p><p><strong>Objective: </strong>To evaluate effectiveness and safety of burr hole microsurgical third ventriculostomy in the treatment of deep midline brain tumors.</p><p><strong>Material and methods: </strong>We used transcortical (25 cases) and transcallosal (8 cases) approaches for microsurgical third ventriculostomy.</p><p><strong>Results: </strong>Initially scheduled biopsy was performed in 19 cases, partial resection in 6 cases, subtotal resection in 4 cases and total resection in 4 cases. All patients underwent microsurgical third ventriculostomy. In 12 cases, stenting of stoma was performed in addition to ventriculostomy. Biopsy was informative in all cases. Postoperative follow-up period ranged from 3 to 44 months (mean 29 months). There was no postoperative hydrocephalus and need for shunting procedure.</p><p><strong>Conclusion: </strong>Burr hole microsurgery may be an alternative to endoscopic surgery for the treatment of pineal, periaqueductal and third ventricular tumors.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 2","pages":"5-13"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Safety of robot-assisted implantation of deep electrodes for invasive stereo-EEG monitoring]. [机器人辅助植入深部电极进行有创立体电子脑电图监测的安全性]。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro20248801128
I M Alekseev, Zh Zh Pekov, N V Pedyash, A A Zuev
{"title":"[Safety of robot-assisted implantation of deep electrodes for invasive stereo-EEG monitoring].","authors":"I M Alekseev, Zh Zh Pekov, N V Pedyash, A A Zuev","doi":"10.17116/neiro20248801128","DOIUrl":"10.17116/neiro20248801128","url":null,"abstract":"<p><p>Robot-assisted implantation of deep electrodes for stereo-EEG monitoring has become popular in recent years in patients with drug-resistant epilepsy. However, there are still few data on safety of this technique.</p><p><strong>Objective: </strong>To assess the incidence of complications in patients with drug-resistant epilepsy undergoing robot-assisted implantation of stereo-EEG electrodes.</p><p><strong>Material and methods: </strong>We retrospectively studied the results of implantation of stereo-EEG electrodes in 187 patients with drug-resistant epilepsy. All patients underwent non-invasive preoperative examination (video-EEG, MRI, PET, SPECT, MEG). In case of insufficient data, stereo-EEG monitoring was prescribed. We determined electrode insertion trajectory using a robotic station and MR images. Implantation of electrodes was carried out using a Rosa robot (Medtech, France). All patients underwent invasive EEG monitoring after implantation.</p><p><strong>Results: </strong>There were 11.25±3 electrodes per a patient. Implantation of one electrode took 7.5±4.9 min. Postoperative MRI revealed electrode malposition in 2.3% of cases. None was associated with complications. The complication rate per electrode was 0.6%. Complications affected stereo-EEG monitoring only in 3 cases (1.6%). The mortality rate was 0.5%. Bilateral implantation (<i>p</i>=0.005), insular (<i>p</i>=0.040) and occipital (<i>p</i>=0.045) deep electrode implantation were associated with lower incidence of complications. Longer duration of the procedure influenced the incidence of electrode placement in the lateral ventricle (<i>p</i>=0.028), and implantation in the frontal lobe was more often associated with epidural placement of electrodes (<i>p</i>=0.039).</p><p><strong>Conclusion: </strong>Robot-assisted implantation of stereo-EEG electrodes is a safe procedure with minimal risk of complications. Rare electrode malposition does not usually affect invasive monitoring.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 1","pages":"28-38"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Laser fluorescence spectroscopy and navigation in surgical treatment of spinal tumors: a systematic review]. [脊柱肿瘤手术治疗中的激光荧光光谱和导航:系统综述]。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro202488011109
N A Konovalov, S V Kaprovoy, Yu M Poluektov, R A Onoprienko, A A Aristov
{"title":"[Laser fluorescence spectroscopy and navigation in surgical treatment of spinal tumors: a systematic review].","authors":"N A Konovalov, S V Kaprovoy, Yu M Poluektov, R A Onoprienko, A A Aristov","doi":"10.17116/neiro202488011109","DOIUrl":"10.17116/neiro202488011109","url":null,"abstract":"<p><p>The main problem in microsurgical resection of spinal cord tumors is excessive surgical aggression. The last one often leads to unsatisfactory clinical and neurological outcomes. Laser fluorescence spectroscopy is a modern neurosurgical approach to distinguish tumor boundaries even if standard visible fluorescence techniques are ineffective.</p><p><strong>Objective: </strong>To evaluate the effectiveness of laser fluorescence spectroscopy alone or in combination with visual 5-ALA fluorescence for improvement of safety and quality of resection, as well as intraoperative diagnosis.</p><p><strong>Material and methods: </strong>Searching for literature data was carried out in accordance with the PRISMA recommendations. The authors reviewed articles independently of each other. These data were systematized.</p><p><strong>Results: </strong>Laser fluorescence spectroscopy is valuable to identify fragments of intramedullary ependyomas in 86% of cases, while visual fluorescence only in 81% of cases. Advisability of this technique for low-grade astrocytomas is still unclear and requires further study. Its effectiveness is 87.5% for extramedullary meningiomas. Neuromas do not accumulate 5-ALA. In addition, this method can be used to determine the boundaries of intradural metastatic lesions.</p><p><strong>Conclusion: </strong>5-ALA fluorescence is a safe and useful intraoperative method for identifying tumor tissue and resection margins in patients with intramedullary or infiltrative extramedullary spinal cord tumors. Visual fluorescence combined with laser spectroscopy is a perspective method for intraoperative visualization of tumor remnants. This approach can improve safety and postoperative outcomes while maintaining resection quality.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 1","pages":"109-114"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[X Congress of Neurosurgeons of Russia]. [俄罗斯第十届神经外科医师大会]。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro202488051118
L Y Kravets, D Y Usachev, V V Krylov, S V Tanyashin
{"title":"[X Congress of Neurosurgeons of Russia].","authors":"L Y Kravets, D Y Usachev, V V Krylov, S V Tanyashin","doi":"10.17116/neiro202488051118","DOIUrl":"10.17116/neiro202488051118","url":null,"abstract":"<p><p>On September 10-13, 2024, the X Congress of Neurosurgeons of Russia was held in Nizhny Novgorod. The congress was held in accordance with the Charter and was the result of more than 30 years of activity of the Association of Neurosurgeons of Russia (ANR).</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 5","pages":"118-122"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142476332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Recovery of consciousness under therapy with benzodiazepines. A case report and literature review]. [苯二氮卓类药物治疗下的意识恢复。病例报告和文献综述]。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2024-01-01 DOI: 10.17116/neiro20248803181
O B Belousova, A N Konovalov, I A Savin, T M Birg, K N Lapteva, D I Pitskhelauri, Sh U Kadyrov, Yu G Sidneva, E A Khhukhlaeva
{"title":"[Recovery of consciousness under therapy with benzodiazepines. A case report and literature review].","authors":"O B Belousova, A N Konovalov, I A Savin, T M Birg, K N Lapteva, D I Pitskhelauri, Sh U Kadyrov, Yu G Sidneva, E A Khhukhlaeva","doi":"10.17116/neiro20248803181","DOIUrl":"10.17116/neiro20248803181","url":null,"abstract":"<p><strong>Background: </strong>Treatment of patients with prolonged and permanent disturbance of consciousness is still an extremely difficult problem. Nowadays, management is based on pathophysiological and molecular mechanisms of impaired consciousness. Several electrophysiological and pharmacological methods were proposed to restore consciousness in appropriate patients.</p><p><strong>Objective: </strong>We present recovery of clear consciousness under therapy with phenazepam and literature review devoted to therapy of these disorders.</p><p><strong>Results and conclusion: </strong>This case confirms available data on drug neuromodulation in complex treatment of patients with prolonged impairment of consciousness and substantiates the need for individual multimodal assessment of structural and functional disorders in prolonged and chronic impairment of consciousness for adequate therapy.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"88 3","pages":"81-89"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141331887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信