Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko最新文献

{"title":"[Chronic epidural electrical stimulation of lumbar enlargement for pain relief after ineffective neurolysis in patients with post-traumatic sciatic neuropathy].","authors":"V P Kondratyev, A V Dekopov, E D Isagulyan, A A Tomskiy","doi":"10.17116/neiro20269003167","DOIUrl":"10.17116/neiro20269003167","url":null,"abstract":"<p><strong>Introduction: </strong>Peripheral nerveinjuries affect approximately 200.000 patients annually in Russia, and sciatic nerve injuries constitute about 8.3% (~16.600 cases). Many patients develop chronic neuropathic pain refractory to standard therapy. Surgical neurolysis provides adequate relief in only 50-80% of cases, and effective alternatives are needed for other patients. Chronic spinal cord stimulation (SCS) is a promising modality for these patients.</p><p><strong>Objective: </strong>To evaluate efficacy and safety of chronic SCS for chronic pain due to post-traumatic sciatic neuropathy refractory to conservative therapy and neurolysis.</p><p><strong>Material and methods: </strong>A retrospective single-center study included 10 patients with persistent neuropathic pain despite prior pharmacotherapy and neurolysis. All patients underwent SCS with pain assessment. The primary efficacy criterion was reduction of VAS score ≥50% after test stimulation period.</p><p><strong>Results: </strong>Positive responses were achieved in 9 out of 10 patients (90%). Mean VAS scores significantly decreased from 7.9±1.3 to 3.3±1.5 (<i>p</i>=0.007). Therapeutic effect was maintained in all responders throughout the follow-up period (3 months-2 years) without complications.</p><p><strong>Conclusion: </strong>Chronic SCS is a highly effective and safe treatment for chronic pain in patients with post-traumatic sciatic neuropathy resistant to standard therapies. These results justify SCS in such clinical scenarios and highlight the need for further prospective studies.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 3","pages":"67-72"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148017654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical presentation of brain abscesses: from classic triad to silent forms].","authors":"A I Baranich, A A Sychev, I A Savin, N V Kurdyumova, M V Sukhorukova, D N Andreev, O I Sharipov, Z Sh Veliev, D S Korotkov","doi":"10.17116/neiro20269005132","DOIUrl":"https://doi.org/10.17116/neiro20269005132","url":null,"abstract":"<p><p>Despite relatively small incidence, brain abscesses are life-threatening with high risk of death and persistent neurological deficits. A key factor limiting early diagnosis is polymorphic and nonspecific clinical presentation.</p><p><strong>Objective: </strong>To analyze the structure and incidence of clinical symptoms in a cohort of patients with brain abscesses treated at the Burdenko Neurosurgical Center.</p><p><strong>Material and methods: </strong>A single-center study was based on medical records of patients with newly diagnosed and confirmed brain abscesses hospitalized for surgical treatment at the Burdenko Neurosurgery Center between January 2022 and December 2025. Verification was based on contrast-enhanced MRI and/or intraoperative data.</p><p><strong>Results: </strong>The study included 41 patients with verified intracranial abscesses. The most common symptoms were headache (51.2%) and focal neurological deficit (48.8%). Fever was detected in 19.5% of patients, classic triad (headache, focal neurological deficit, fever) - in only 7.3% of patients. There were no symptoms (subclinical presentation) in 19.5% of patients. Atypical and silent forms of disease comprised 73.2%.</p><p><strong>Conclusion: </strong>Silent and atypical forms account for 73.2% of cases, while classic triad of symptoms is recorded in only 7.3% of patients. This decreases its diagnostic value. In this regard, patients with focal neurological symptoms or severe headaches, even afebrile cases, and previous possible cause of infection (otitis, sinusitis, odontogenic infection, etc.) seem reasonable not only to have brain abscess but also be scheduled for neuroimaging with specialized modes.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 5","pages":"32-38"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Association of tumor metabolic parameters on amino acid PET/CT with EGFR expression].","authors":"N B Vikhrova, D B Kalaeva, S F Drozd, O V Kalennik, A V Kosyrkova, G V Danilov, G V Pavlova, I N Pronin, D Yu Usachev","doi":"10.17116/neiro20269005139","DOIUrl":"https://doi.org/10.17116/neiro20269005139","url":null,"abstract":"<p><strong>Background: </strong>According to the 2021 WHO classification, molecular-genetic profiling of CNS tumors is the standard for diagnosis. Beyond <i>IDH</i> mutation status, EGFR receptor alterations are significant factors associated with unfavorable prognosis and treatment resistance. Identifying correlations between genetic abnormalities and amino acid PET/CT parameters is important for discovering non-invasive surrogate markers of aggressive phenotype.</p><p><strong>Objective: </strong>To analyze the relationship between <i>EGFR</i> / <i>EGFRvIII</i> gene expression and metabolic PET/CT parameters in patients with glial tumors.</p><p><strong>Material and methods: </strong>The study included 71 adults with gliomas: glioblastoma (<i>n</i>=52), Grade 3 astrocytoma (<i>n</i>=11), and Grade 3 oligodendroglioma (<i>n</i>=8). All patients underwent PET/CT with ¹¹C-MET (<i>n</i>=41) or ¹⁸F-FET (<i>n</i>=30). The tumor-to-background ratio (TBR) and metabolic tumor volume (MTV) were calculated using a TBR segmentation threshold of 1.6. <i>EGFR</i> / <i>EGFRvIII</i> expression was determined via RT-PCR.</p><p><strong>Results: </strong><i>EGFR</i> expression was significantly higher in glioblastomas compared to astrocytomas and oligodendrogliomas. A significant positive correlation was found between <i>EGFR</i> and MTV (Rs=0.44, <i>p</i>=0.02). In patients with astrocytomas, there was a moderate negative correlation between TBR and <i>EGFR</i> expression (Rs=-0.64, <i>p</i>=0.04). No significant correlations were observed in glioblastomas and oligodendrogliomas that may be attributed to high variability of <i>EGFR</i>. <i>EGFRvIII</i> was expressed in 25% of gliomas (exclusively glioblastomas). However, we found no association with metabolic parameters (possibly due to small sample size).</p><p><strong>Conclusion: </strong>Differences in <i>EGFR</i> expression patterns across various glioma types were demonstrated. Correlation between <i>EGFR</i> gene expression and tumor metabolic volume suggests potential role for PET/CT parameters as prognostic markers.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 5","pages":"39-45"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Intraoperative rupture of cerebral aneurysms during microsurgical clipping as a risk factor of residual aneurysm enlargement].","authors":"Yu V Pilipenko, Sh Sh Eliava, M B Kholmatov, D A Starostenko, D N Okishev, An N Konovalov, F V Grebenev","doi":"10.17116/neiro20269005125","DOIUrl":"https://doi.org/10.17116/neiro20269005125","url":null,"abstract":"<p><strong>Background: </strong>Aneurysm neck clipping is preferable for saccular aneurysms due to stable occlusion. However, postoperative follow-up angiography reveals residual aneurysm in some cases after clipping. Long-term outcomes depend on clipping quality. Currently, there is no consensus regarding further management of these patients.</p><p><strong>Objective: </strong>To analyze residual cerebral aneurysms within the first year after surgery, and to identify prognostic factors of enlargement and rupture of aneurysm remnant.</p><p><strong>Material and methods: </strong>In 2024, clipping of 654 cerebral aneurysms in 550 patients was performed. Residual aneurysms were identified in 49 (7.5%) cases. Clipping quality was estimated in accordance with classification by Yu.V. Pilipenko. Three patients with partial exclusion (R4) underwent redo surgery in early postoperative period. Among 46 patients with residual aneurysms, we enrolled 25 patients with available clinical and angiographic data within one year after surgery.</p><p><strong>Results: </strong>There were no CT signs of residual aneurysm enlargement in 22 (88%) out of 25 cases. In two patients (8%), enlargement of remnant required redo clipping. Fatal rupture of aneurysm remnant occurred in 1 (4%) case. All three patients experienced intraoperative aneurysm rupture during primary surgery.</p><p><strong>Conclusion: </strong>Intraoperative rupture significantly increases the risk of residual aneurysm enlargement. Localization in Anterior communicating artery (ACjoA) and clipping quality ≥R3 are potential risk factors requiring further studies of larger cohorts.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 5","pages":"25-31"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Biopsy in the treatment of children with diffuse brainstem tumors].","authors":"S S Ozerov, A L Levov, A N Kislyakov, D A Skobeev, M A Kolcheva, V N Umerenkov, M I Livshits, G E Chmutin, E V Kumirova, V V Gorev","doi":"10.17116/neiro20269002129","DOIUrl":"10.17116/neiro20269002129","url":null,"abstract":"<p><p>Background. Diffuse brainstem tumors account for 10-20% of all brain tumors in children. These neoplasms are the leading cause of death in pediatric neuro-oncology. There are no effective treatments for this disease. Overall survival rarely exceeds 1.5-2 years.</p><p><strong>Objective: </strong>Biopsy of diffuse brainstem tumors to determine their histological type and molecular genetic markers; to identify potential targets for targeted therapy.</p><p><strong>Material and methods: </strong>In 2021-2025, 26 patients with diffuse brainstem tumors underwent surgery at the Morozovskaya Children's Clinical Hospital. Age of patients was 1.5-17 years, duration of disease - from 1 week to 13 months. There was primary tumor in 96% of cases. Preliminary diagnosis was based on clinical presentation and MRI. Stereotactic biopsy using BrainLab neuronavigator via transcerebellar approach was performed in 24 patients, open biopsy - in 2 cases.</p><p><strong>Results: </strong>The tumor was verified in 24 (92%) patients. Brain tissue was obtained from two patients. According to morphological data, 80% of patients had diffuse midline glioma. Ganglioglioma was detected in one case, high-grade glioma in one case, and low-grade glioma in one case. All patients underwent immunohistochemical examination of specimen, and 58% were examined using the NGS program. The <i>H3K27M</i> mutation was detected in 71% of cases, <i>BRAF-V600E</i> mutations in 2 patients, and <i>FGFR2</i> gene mutation in 1 patient. Targeted therapy was based on information about mutations. The overall 2-year survival rate was 20%, event-free 2-year survival - 0%. Event-free survival of a patient with the <i>BRAF-V600E</i> mutation who received targeted therapy was 21 months.</p><p><strong>Conclusion: </strong>Stereotactic biopsy of diffuse brainstem tumors can be performed safely. Identification of targets for personalized therapy may be essential for management of these patients.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 2","pages":"29-36"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Asymmetric sliding knots for microsutures for skull base defect repair after transnasal endoscopic surgery].","authors":"M A Kutin, E V Shelesko, D V Fomichev, O I Sharipov, D N Andreev, I V Chernov, N A Azarova, Yu V Strunina, A D Donskoy, O A Rastvorova, D Sh Adueva, D A Konyashin, G G Maksyutova, P L Kalinin","doi":"10.17116/neiro20269003173","DOIUrl":"10.17116/neiro20269003173","url":null,"abstract":"<p><p>The advantage of asymmetrical sliding knot is that it is tightened by pulling only one «main» end of suture, while the other «wrapped» end is inserted into the wound. This method eliminates the need for additional instruments or devices to insert the knot into a narrow and deep wound.</p><p><strong>Objective: </strong>To evaluate feasibility of asymmetrical sliding knots for microsutures in transnasal endoscopic skull base repair.</p><p><strong>Material and methods: </strong>Asymmetric sliding suture was used to attach free autofascial flap to dura mater edges in 25 cases of transnasal endoscopic surgeries with intraoperative cerebrospinal fluid leakage. Craniopharyngiomas were resected in 19 cases, pituitary adenoma in 1 case, meningocele in 1 case, sinonasal carcinomas in 2 cases, chondrosarcoma in 1 case and chordoma in 1 case.</p><p><strong>Results: </strong>Postoperative cerebrospinal fluid leakage was not observed in any case.</p><p><strong>Conclusion: </strong>We confirmed feasibility of asymmetric sliding knots to form microsutures in transnasal endoscopic skull base repair. The key technical parameters of necessary sutures, specifics of needle insertion through the dura mater and free autofascial flap, limitations and difficulties encountered by the authors are described. Sliding interrupted microsutures can be recommended to form dense layer of autologous tissues in transnasal endoscopic skull base repair.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 3","pages":"73-79"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148017585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Facial neuropathy in early postoperative period after resection of cerebellopontine angle tumor using various modalities of intraoperative neurophysiological monitoring: a systematic review and meta-analysis].","authors":"E G Seliverstova, M V Sinkin, A A Grin","doi":"10.17116/neiro202690011100","DOIUrl":"10.17116/neiro202690011100","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the incidence of facial neuropathy after microsurgical resection of cerebellopontine angle (CPA) tumors using various intraoperative neurophysiological monitoring (IONM) scenarios.</p><p><strong>Material and methods: </strong>We analyzed 792 articles from PubMed, Google Scholar, Web of Science, and e-library databases and selected 35 eligible studies. There were 4.657 patients including 1.173 ones with facial neuropathy after CPA tumor resection. Statistical analysis was performed using OpenMeta Analyst software. Differences were significant at <i>p</i>< 0.05.</p><p><strong>Results: </strong>The pooled incidence of postoperative facial neuropathy after CPA tumor resection was 28.9% (95% CI: 23.3% - 34.6%). In case of multimodal IONM, this value decreased to 23.5% (95% CI: 17.9% - 29.2%). This demonstrates significant effectiveness of this approach compared to direct facial nerve stimulation and resting EMG monitoring.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 1","pages":"100-107"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146158539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Extradural angiolipoma of the thoracic spine: a case report and literature review].","authors":"N D Shmelev, N A Konovalov, E S Brinyuk, S V Kaprovoi, R A Onoprienko, B A Zakirov, L R Gabrielyan, K V Kuzmina","doi":"10.17116/neiro202690031102","DOIUrl":"10.17116/neiro202690031102","url":null,"abstract":"<p><strong>Background: </strong>Spinal angiolipomas (SA) are rare primary tumors accounting for 0.14-1.2% of all spinal cord and spine tumors and approximately 3% of extradural spinal neoplasms (<0.1% of all primary CNS tumors). Histologically, SA consists of mature adipocytes and abnormally developed vessels. Clinical presentation of this tumor is due to severe spinal cord compression.</p><p><strong>Material and methods: </strong>The authors present a 33-year-old patient with severe spinal cord compression who underwent resection of Th6-Th8 spinal angiolipoma. The Pubmed, Medline, EMBASE, Cochrane Library and eLibrary databases were screened using appropriate keywords.</p><p><strong>Results and discussion: </strong>Extradural tumor > 5 cm causing severe dural sac compression was excised. In early postoperative period, there were complete regression of preoperative lower spastic paraparesis and gait improvement.</p><p><strong>Conclusion: </strong>SAs are extremely rare, and their total resection with preservation or improvement of neurological status is possible in a specialized hospital.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 3","pages":"102-106"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148017769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Fat grafting for frontotemporal contour restoration after neurosurgery].","authors":"V A Lukyanchikov, V A Gorozhanin, E V Orlova, I A Kirilenko","doi":"10.17116/neiro20269004144","DOIUrl":"10.17116/neiro20269004144","url":null,"abstract":"<p><strong>Background: </strong>Currently, aesthetic assessment becomes important after head and neck surgeries. Anterolateral approaches are common in neurosurgery, and frontotemporal contour deformities with asymmetry are the most common aesthetic defects. In 68% of cases, such sequelae can lead to severe psycho-emotional disorders. Autologous fat grafting (lipofilling) is a minimally invasive method with low risk of complications and stable long-term results. It is widely used in plastic reconstructive surgery but not routine after neurosurgical interventions.</p><p><strong>Material and methods: </strong>We present 4 cases of autologous fat grafting in patients with frontotemporal deformities after previous craniotomies. A 5-point Likert scale was used for subjective assessment of aesthetic outcomes after lipofilling.</p><p><strong>Results: </strong>\"Complete satisfaction\" with results was achieved in three patients; one patient rated the result as \"satisfactory\". No postoperative complications were registered. Mean volume of injected autologous fat tissue per a procedure was 23.5 ml. The second procedure of lipofilling was required for two patients to achieve satisfactory results.</p><p><strong>Conclusion: </strong>These cases demonstrate feasibility of autologous fat grafting in patients with frontotemporal deformities after previous craniotomies. This method can be used as one of the options for minimally invasive soft tissue augmentation in temporal region considering graft survival, acceptable aesthetic outcomes and low risk of complications. When planning treatment, it is necessary to account for natural resorption of autologous fat tissue that often necessitates multiple lipofilling procedures.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 4","pages":"44-51"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148685877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Molecular diagnosis of non-syndromic craniosynostosis: new challenges for real clinical practice].","authors":"E S Makashova, A V Efremova, L A Satanin, I V Kanivets","doi":"10.17116/neiro202690051100","DOIUrl":"https://doi.org/10.17116/neiro202690051100","url":null,"abstract":"<p><p>Craniosynostoses (CS) are a congenital malformation caused by absence or premature closure of skull sutures. This leads to deformation and impaired growth of skull. Traditionally, syndromic and non-syndromic forms are distinguished. For a long time, it was believed that molecular genetic mechanisms are significant exclusively for syndromic CS. However, clear data on involvement of somatic and germinal mutations in pathogenesis of non-syndromic forms were accumulated in recent years. Currently, there are no unified clinical guidelines defining the strategy for molecular genetic diagnosis for non-syndromic CS. This creates difficulties for neurosurgeons when choosing the optimal diagnostic method. The purpose of the article was to analyze modern ideas about effectiveness of various methods of molecular diagnosis of non-syndromic CS and to evaluate their role in routine clinical practice of neurosurgical departments.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 5","pages":"100-105"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}