Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko最新文献

{"title":"[Influence of surgical access on bacterial contamination of autologous blood in neurosurgical patients].","authors":"O K Kvan, N B Teryaeva, M V Sukhorukova, O Yu Titov, A Yu Lubnin, A V Kozlov, D Yu Usachev","doi":"10.17116/neiro20258905179","DOIUrl":"https://doi.org/10.17116/neiro20258905179","url":null,"abstract":"<p><p>All perioperative invasive procedures, including those associated with autologous blood circulation in extracorporeal circuit, should be considered as a risk factor of infectious complications. Despite perioperative antibiotic prophylaxis and compliance with standards for hardware reinfusion in neurosurgical interventions, bacterial contamination of autologous blood occurs in 38.3% of cases. One of the risk factors may be surgical approach.</p><p><strong>Objective: </strong>To analyze the influence of surgical access on bacterial contamination of autologous blood and effectiveness of complex decontamination in hardware reinfusion in neurosurgery.</p><p><strong>Material and methods: </strong>The study included 107 patients with CNS tumors and high risk of intraoperative blood loss with hardware blood reinfusion. Three surgical approaches were used: transcranial, extended transcranial with opening of paranasal sinuses and transnasal endoscopic access. The protocol of perioperative antibiotic prophylaxis was used in all patients. We evaluated bacterial contamination after decontamination using microbiological testing.</p><p><strong>Results: </strong>Surgical approach significantly affected the risk of bacterial contamination of autologous blood in neurosurgical patients (<i>p</i><0.001). The minimum risk was observed for transcranial approaches (29%), moderate - for extended transcranial approaches (50%), maximum - for transnasal endoscopic approaches (100%). This pattern is not presented in available literature. There were no local or systemic infectious complications in postoperative period.</p><p><strong>Conclusion: </strong>Transfusion of autologous blood is quite safe in case of appropriate perioperative antibiotic prophylaxis and all measures aimed at blood decontamination. Approaches with opening the paranasal sinuses require 4-stage decontamination (cefuroxime+washing+leukofiltration+irradiation).</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"89 5","pages":"79-86"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145303763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis of a series of 14 clinical cases of neurosurgical treatment of hypophysitis].","authors":"L I Astafieva, D V Fomichev, I V Chernov, L V Shishkina, I S Klochkova, M G Pavlova, A C Arustamyan, O A Rastvorova, D A Starostenko, A N Shkarubo, M A Kutin, P L Kalinin","doi":"10.17116/neiro20258902139","DOIUrl":"10.17116/neiro20258902139","url":null,"abstract":"<p><p>Primary hypophysitis is a rare disease that is usually diagnosed retrospectively after surgery for suspected tumors of the sellar region (pituitary adenomas, craniopharyngiomas, etc.). The most common variant of the primary forms is lymphocytic hypophysitis, characterized by the presence of lymphocytes in the inflammatory infiltrate. Granulomatous hypophysitis is the second most common variant of the disease, the cause of which remains unknown.</p><p><strong>Objective: </strong>To study the frequency and nature of clinical manifestations, the features of MRI of the brain, as well as the results of neurosurgical treatment of patients with a confirmed histological diagnosis of hypophysitis.</p><p><strong>Material and methods: </strong>A retrospective analysis of the case reports of 14 patients with histologically confirmed diagnosis of lymphocytic (13 cases) and granulomatous (1 case) hypophysitis operated at the Burdenko Neurosurgical Center.</p><p><strong>Results: </strong>In none of the cases before the operation, according to the MRI data, the diagnosis of \"hypophysitis\" was made. Clinical symptoms were manifested by headaches in 12 patients, decreased acuity and/or visual field impairment in 9 patients, oculomotor impairments in 2 patients. Hypopituitarism was detected in 12 cases, and diabetes insipidus in 8 cases.</p><p><p>After surgery, 7 patients had a regression of headache and improved vision, in 5 cases there was no dynamics, in 1 case vision deteriorated. In all 8 patients with diabetes insipidus, it persisted after surgery. There were no new cases of diabetes insipidus. Panhypopituitarism was noted in all patients.</p><p><strong>Conclusion: </strong>Given the difficulty of diagnosing hypophysitis without morphological verification, as well as the rarity of these cases, prospective multicenter studies are needed to study the pathognomonic signs of hypophysitis and improve their neuroimaging methods.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"89 2","pages":"39-47"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Correction of the effect of direct oral and parenteral anticoagulants in hemorrhagic stroke].","authors":"A I Baranich, A A Sychev, I A Savin, V G Kudrina, A V Kozlov","doi":"10.17116/neiro202589011109","DOIUrl":"10.17116/neiro202589011109","url":null,"abstract":"<p><strong>Background: </strong>Hemorrhagic stroke is associated with high risk of adverse outcome and follows intake of anticoagulants and antiplatelet agents in 25% of cases. The latest clinical guidelines of the Neurocritical Care Society for correction (reversal) of the effect of anticoagulants and antiplatelet agents in hemorrhagic stroke were published in 2016.</p><p><strong>Material and methods: </strong>In accordance with PRISMA recommendations, we reviewed the PubMed, eLibrary and UpToDate databases to a depth of 5 years and selected 48 articles.</p><p><strong>Results and discussion: </strong>Direct oral anticoagulants are currently common. To reverse their effect, one can use specific antidotes (idarucizumab is recommended for dabigatran, andexanet alfa (not yet registered In Russia) for factor Xa inhibitors (rivaroxaban, apixaban)) and combination of prothrombin complex concentrate and tranexamic acid. Protamine sulfate is antidote for unfractionated and low molecular weight heparins. Protamine sulfate completely inactivates unfractionated heparin, but it is less effective against low molecular weight heparin. It is characterized by high probability of anaphylactic reactions, especially after repeated administrations. The effectiveness of andexanet alpha and activated factor VII for reversing the effect of low molecular weight heparin is being studied. Fondaparinux sodium is used for heparin-induced thrombocytopenia. Protamine sulfate is ineffective for reversing the effect of fondaparinux. One can use prothrombin complex concentrate and andexanet alpha, but their effectiveness is unclear. Ciraparantag is being studied in clinical trials. Apparently, ciraparantag is highly effective as an antidote for various anticoagulants.</p><p><strong>Conclusion: </strong>Early hemostatic therapy and reversal of anticoagulant effects in patients with hemorrhagic stroke significantly reduce the risk of adverse outcomes. This problem is being studied. Regular literature review with creation of updated clinical guidelines is needed.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"89 1","pages":"109-115"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[En plaque convexity hyperostotic meningioma: 69 cases from a singlecenter].","authors":"A V Kozlov, K V Efremov, M V Galkin, O K Kvan, M V Ryzhova, Yu A Strunina, O Yu Titov, S V Tanyashin","doi":"10.17116/neiro20258901120","DOIUrl":"10.17116/neiro20258901120","url":null,"abstract":"<p><strong>Background: </strong>To date, 16 cases of en plaque hyperostotic meningioma of the convexity have been described. There are no clinical guidelines for the treatment of such patients.</p><p><strong>Objective: </strong>To study the factors influencing the results of surgical treatment of en plaque convexity hyperostotic meningioma, to formulate the appropriate decision-making algorithm.</p><p><strong>Material and methods: </strong>A retrospective total group of 69 patients with en plaque convexity hyperostotic meningioma who underwent surgery at Burdenko Neurosurgical Center between 2014 and 2023. We analyzed clinical manifestations, tactics and results of surgery and radiotherapy using statistical methods.</p><p><strong>Results and discussion: </strong>Total resection of small local non-infiltrative hyperostotic meningioma not involving the superior sagittal sinus did not cause neurological deterioration. In case of spread infiltrative hyperostotic meningiomas, the best results (including regression of intracranial hypertension in all cases) were obtained after non-radical surgeries (resection of hyperostosis without wide excision of the dura or even without dura opening). Extent of resection of involved dura and intracranial tumor did not affect relapse-free survival. Additional morbidity at discharge from the clinic was 35%, after ≥6 months - 16%. The most common (27.5%) complication was pseudomeningocele. Redo surgery rate for pseudomeningocele - 7%, hematomas - 7%, wound infection - 6%. There were no mortality in the series. Radiotherapy increased relapse-free survival without statistical confirmation.</p><p><strong>Conclusion: </strong>Total resection provides optimal results in patients with small convexity hyperostotic meningioma and no brain invasion. Resection of hyperostosis and expansive cranioplasty are preferable for large and giant convexity hyperostotic meningioma involving venous sinuses and / or the brain.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"89 1","pages":"20-29"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Mystery of the illness of the great painter I. Repin. By the 180th anniversary].","authors":"A V Gorozhanin, A G Fedyakov, V E Lovyagina","doi":"10.17116/neiro2025890116","DOIUrl":"10.17116/neiro2025890116","url":null,"abstract":"<p><p>There was the 180^th anniversary of Ilya Yefimovich Repin on August 5, 2024. He is the greatest Russian realist artist of the XIX century, a master of historical and genre painting, as well as outstanding portraitist. Repin's biography is unique. He was a professor and then academician of the Imperial Academy of Arts, teacher, author of memoirs and essays on fine art. After the age of 40, the artist developed a disease with impaired function of the right hand. Therefore, he retrained to write with his left hand. Accurate lifetime and post-mortem diagnosis was not established. The appearance of the artist's right hand represented by posthumous plaster cast indicates neuropathy of the right ulnar nerve.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"89 1","pages":"6-10"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Basal encephalocele complicated by nasal liquorrhea in patients with craniosynostosis].","authors":"N A Chernikova, L A Satanin, E V Shelesko, N E Zakharova, S G Rudnev, D N Zinkevich","doi":"10.17116/neiro20258904161","DOIUrl":"https://doi.org/10.17116/neiro20258904161","url":null,"abstract":"<p><p>The combination of basal encephalocele with craniosynostosis is a rare clinical situation. Few observations of these two pathologies combination are described in the literature. Objective: to analyze own sample of patients to determine possible causes of encephalocele formation and surgical treatment strategy.</p><p><strong>Material and methods: </strong>Medical records of 4 patients with combination of encephalocele and craniosynostosis were analyzed. Data on complaints, medical history, results of medical specialists' examinations were studied. Data of CT and MRI, craniometric analysis were assessed. Obtained results were compared with literature data.</p><p><strong>Results: </strong>Encephalocele development in patients with craniosynostosis was secondary and related to various causes such as traumas, iatrogenic injury, intracranial hypertension. The most significant factor in occurrence and development of nasal liquorrhea relapse is increased cerebrospinal fluid pressure.</p><p><strong>Conclusion: </strong>The treatment strategy for patients with basal encephalocele can be determined by the presence of intracranial hypertension and its increase after nasal liquorrhea elimination. One of the possible signs of long-lasting intracranial hypertension in children is a symptom of increased convolutional markings pattern according to the CT. If this sign is detected, it is justified to perform transcranial plastic surgery of cerebrospinal fluid-venous fistula with simultaneous reconstruction of the skull bones.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"89 4","pages":"61-68"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Malignancy of fibrous dysplasia of the calvarial bone in patient with McCune-Albright syndrome: clinical observation and literature review].","authors":"M M Rakityanskiy, E V Vinogradov, I N Pronin, M A Semushin, A Yu Lubnin, N A Mazerkina, O A Shchagina, O K Kvan, K A Kuldashev, L A Satanin, A V Kozlov","doi":"10.17116/neiro20258904187","DOIUrl":"https://doi.org/10.17116/neiro20258904187","url":null,"abstract":"<p><p>Malignant transformation of fibrous dysplasia in McCune-Albright syndrome is observed in less than 1% of cases, thus osteosarcoma is developing more frequently. According to the search in the PubMed database over the last 5 years, 13 publications were found, but none of them described cerebral cranium damage.</p><p><strong>Material and methods: </strong>A clinical observation of a 27-year-old patient with polyostotic fibrous dysplasia, skin manifestations and prolactin+HGH-secreting pituitary adenoma - McCune-Albright syndrome - without GNAS gene mutation is described. The patient had a rapidly increasing formation in the left temporoparietal region, which reached 18×20×15 cm, accompanied by local pain and fever 4 months prior to hospitalization. Diagnosis of osteosarcoma was verified by biopsy. Neoadjuvant chemotherapy in the presence of intracranial hypertension and giant tumor has been refused.</p><p><strong>Results: </strong>Preoperative embolization of tumor vessels with polyvinyl alcohol emboli was moderately effective. Tumor node has been removed, blood loss amounted to 5500 ml, blood autodonation, cell saver, 1 dose of donor erythrocytes were used. On the 1st day, the patient was transferred to the clinical unit, pain and fever ceased. He was discharged on the 8th day in satisfactory condition. Nevertheless, chemotherapy in the home area was not performed and the patient died from the disease progression in 1.5 months. The algorithm of care in osteosarcoma - neoadjuvant chemotherapy, tumor resection and adjuvant treatment.</p><p><p>However, the results of such treatment remain generally unsatisfactory. The algorithm of treatment for patients with fibrous dysplasia malignancy in McCune-Albright syndrome is not presented in the literature. The surgical intervention resulted in the removal of the main tumor volume and regression of intracranial hypertension, but did not significantly affect the patient's fate in the absence of adjuvant chemotherapy.</p><p><strong>Conclusion: </strong>The possibility of malignant neoplasms development from fibrous dysplasia in McCune-Albright syndrome must be taken into consideration. The development of an algorithm for care in such patients requires accumulation of material and its analysis.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"89 4","pages":"87-97"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Microsurgical treatment of 723 cerebral aneurysms: a single-center prospective study].","authors":"Sh Sh Eliava, Yu V Pilipenko, M B Kholmatov, O B Belousova, A S Kheyreddin, D N Okishev, An N Konovalov, F V Grebenev","doi":"10.17116/neiro20258903160","DOIUrl":"https://doi.org/10.17116/neiro20258903160","url":null,"abstract":"<p><strong>Background: </strong>Treatment of cerebral aneurysms is followed by more favorable results in hospitals with at least 50-100 patients annually. In this regard, analysis and comparison of data from various clinics are of interest.</p><p><strong>Objective: </strong>To analyze the features of microsurgical treatment of cerebral aneurysms, immediate clinical and angiographic results.</p><p><strong>Material and methods: </strong>There were 600 patients with cerebral aneurysms aged 16-79 years (mean 53.7±12) between 01/09/2024 and 12/29/2024. There were multiple aneurysms in 29.7% of patients. Saccular and fusiform aneurysms were observed in 95% and 5% of patients. Giant aneurysms were detected in 1.8% of cases. Aneurysms of anterior and middle cerebral arteries accounted for 74.3%. Forty-nine (8.2%), 29 (4.8%) and 99 (16.5%) patients underwent surgery in acute (1-14 days), subacute (15-21 days) and delayed (>21 days) period of hemorrhage. Cerebral aneurysms with mass effect were noted in 8 patients (1.3%), ischemia - in 15 (2.5%) cases. Incidental aneurysms were diagnosed in 400 patients (66.7%).</p><p><strong>Results: </strong>Aneurysm neck clipping was performed in 97.5% of cases, trapping without anastomosis - 0.6%, trapping with anastomosis - 1.2%, reinforcement of microaneurysms with autologous muscle - in 0.7% of cases. There was mRS score 0-2 after 14 postoperative days in 96.3% of patients. Postoperative complications were noted in 14% of cases. There were no fatal cases. Complete exclusion of saccular aneurysms was achieved in 92.2% of cases, fusiform aneurysms - in 69.5% of cases.</p><p><strong>Conclusion: </strong>Microsurgical treatment of patients with cerebral aneurysms in high-flow hospitals demonstrates favorable clinical and angiographic results. Favorable postoperative results require modern methods of preoperative diagnostics, accumulation of experience by neurosurgeons, adherence to algorithms for choosing a treatment method and current intensive care protocols, as well as preparation for surgery taking into account surgical risks associated with concomitant diseases.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"89 3","pages":"60-67"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Surgery for enlarged perivascular spaces: primary experience].","authors":"A A Veselkov, A V Gavryushin, S A Maryashev, D I Pitskhelauri, T L Bekhtereva, A N Konovalov","doi":"10.17116/neiro20258902123","DOIUrl":"10.17116/neiro20258902123","url":null,"abstract":"<p><p>Perivascular spaces are cavities surrounding cerebral and spinal cord vessels and filled with cerebrospinal or intercellular fluid. Abnormal enlargement of these spaces can lead to neurological symptoms. Currently, there are no clear approaches to surgical treatment of this pathology. We set ourselves the task of analyzing the literature data, as well as presenting own clinical observations and sharing the experience of microsurgical treatment of this pathology.</p><p><strong>Material and methods: </strong>We reviewed the PubMed databases between 2009 and 2024. We analyzed own small sample (<i>n</i>=5) of patients with dilated perivascular spaces who underwent microsurgical treatment between 2009 and 2024. Four patients underwent microsurgical cystoventriculostomy, one patient - microsurgical cystocysternostomy and biopsy.</p><p><strong>Results: </strong>Microsurgical cystoventriculostomy and cyst drainage were less effective than expected. Four out of five patients developed new neurological symptoms after surgery, while baseline symptoms did not significantly regress.</p><p><strong>Conclusion: </strong>To date, cerebrospinal fluid shunting is still the main surgical method for dilated perivascular spaces accompanied by intracranial hypertension.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"89 2","pages":"23-28"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Dynamics of caudal dystopia of cerebellar tonsils in patients with craniosynostosis following posterior cranial distraction].","authors":"L A Satanin, N A Chernikova, S G Rudnev, E A Khukhlaeva, V G Solonichenko, V V Roginsky","doi":"10.17116/neiro20258905154","DOIUrl":"https://doi.org/10.17116/neiro20258905154","url":null,"abstract":"<p><p>The main cause of caudal dystopia of cerebellar tonsils (CDCT) in craniosynostosis (CS) is underdevelopment of posterior cranial fossa (PCF) with its insufficient volume. Therefore, posterior cranial distraction seems to be perspective for effective enlargement of intracranial volume.</p><p><strong>Objective: </strong>To evaluate CDCT dynamics in patients with CS after posterior cranial distraction.</p><p><strong>Material and methods: </strong>There were 136 patients with CS who underwent posterior cranial distraction between 2011 and 2022. Of these, 32 ones were included in this study. These patients were diagnosed with CDCT after MRI. Clinical, radiological and craniometric data were analyzed.</p><p><strong>Results: </strong>PCF volume increased by 34.8% after posterior cranial distraction. CDCT completely regressed in 56.3% of patients. Older age of patients, baseline level of CDCT and posterior angle of skull base contributed to complete regression of CDCT.</p><p><strong>Conclusion: </strong>Posterior cranial distraction below the confluence of sinuses with craniovertebral junction decompression effectively increases intracranial and PCF volumes. In most cases, this leads to decrease or complete regression of CDCT. Genesis of CDCT and associated hydrocephalus in CS is multifactorial. Thus, persistent CDCT and/or progressive hydrocephalus may occur and necessitate additional monitoring and, if necessary, neurosurgical intervention.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"89 5","pages":"54-63"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145303591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}