Z H Pan, X Jin, X H Yang, L Y Shao, T L Li, Y Guo, D J Deng, C H Chi
{"title":"[Optimizing a standardized management model for chronic obstructive pulmonary disease in primary healthcare institutions].","authors":"Z H Pan, X Jin, X H Yang, L Y Shao, T L Li, Y Guo, D J Deng, C H Chi","doi":"10.3760/cma.j.cn112137-20250218-00371","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20250218-00371","url":null,"abstract":"<p><p>Chronic obstructive pulmonary disease (COPD) affects nearly 100 million individuals in China and has become a major public health challenge. Primary healthcare institutions serve as the frontline for implementing comprehensive COPD management strategies. However, current primary care practices face multiple limitations, including inadequate screening capacity, insufficient resource allocation, suboptimal hierarchical diagnosis systems, and low public awareness of the disease. Based on policy guidance, this article explores strategies for early screening high-risk populations, optimization of hierarchical diagnosis practices, development of primary-level respiratory specialty clinics, application of artificial intelligence-assisted diagnosis, and adaptation of international experience. We explore multidimensional pathways to standardize COPD management in primary care settings, providing a reference for the prevention, control, and precision management of COPD in China.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 26","pages":"2154-2161"},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Clinical characteristics and treatment strategies of nasopharyngeal carcinoma with concurrent thyroid cancer].","authors":"H F Li, R C Zou, J L Liang, R Q Xie, M Y Chen","doi":"10.3760/cma.j.cn112137-20250428-01075","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20250428-01075","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the clinical characteristics and treatment strategies of nasopharyngeal carcinoma (NPC) with concurrent thyroid cancer (TC). <b>Methods:</b> A case series study was carried out. The clinical data of NPC patients with concurrent TC diagnosed by pathology and with complete follow-up data who were initially treated in Sun Yat-sen University Cancer Center from January 2017 to December 2023 were retrospectively reviewed. Patients were divided into NPC-first treatment group and TC-first treatment group based on the treatment sequence. Clinical characteristics, treatment strategies and prognosis of patients were compared between the two groups. <b>Results:</b> A total of 53 cases (28 males and 25 females) aged [<i>M</i> (<i>Q</i><sub>1</sub>, <i>Q</i><sub>3</sub>)] 42 (34, 48) years were included. Sixteen (31.2%) patients underwent TC treatments first, while 37 patients (69.8%) underwent NPC treatments first. There were 64.2% (34/53) patients diagnosed based on NPC-specific ENT symptoms. The Epstein-Barr virus (EBV) DNA-negative rate [62.5% (10/16) vs 24.3% (9/37), <i>P</i>=0.008], the rate of double-lobe thyroid lesions based on positron emission tomography/computed tomography (PET/CT) scans (3/6 vs 1/26, <i>P</i>=0.015), the rate of cervical lymph node metastasis of TC based on ultrasound scans [31.2% (5/16) vs 5.4% (2/37), <i>P</i>=0.021] and the rate of stageⅠ-Ⅲ NPC [87.5% (14/16) vs 54.1% (20/37), <i>P</i>=0.020] were higher in patients who underwent TC treatment first compared with those who underwent NPC treatment first. The interval between NPC and TC treatments was longer in NPC-first treatment group than that of TC-first treatment group [166 (125, 281) days vs 74 (29, 90) days, <i>P</i><0.001]. In patients who underwent TC treatment first, fewer level Ⅵ cervical lymph nodes were included in the clinical target volume (CTV) compared with those who underwent NPC treatment first [10.0% (2/20) vs 40.0% (16/40), <i>P</i>=0.017]. After 38.7 (18.3, 52.3) months of follow-up, there was no statistically significant difference in expected 3-year progression free survival rates and overall survival rates between the two groups (87.3% vs 83.6% and 100% vs 87.5%, respectively, both <i>P</i>>0.05). <b>Conclusions:</b> The majority of NPC patients with concurrent TC were initially diagnosed due to NPC-related symptoms, consequently leading to a higher proportion receiving NPC treatment as their primary therapy. For NPC patients with concurrent TC, receiving TC treatment first facilitates the guidance of CTV.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 26","pages":"2203-2211"},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z Y Wang, S Q Yang, S X Wang, X Chen, M Z Cheng, Y F Yu
{"title":"[Protective effect and its mechanism of diselenide cross-linked nano-loaded astaxanthin on gentamicin-induced vestibular toxicity in mice].","authors":"Z Y Wang, S Q Yang, S X Wang, X Chen, M Z Cheng, Y F Yu","doi":"10.3760/cma.j.cn112137-20250118-00159","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20250118-00159","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the protective effect and its mechanism of intratympanic administration of diselenide cross-linked nano-carriers of astaxanthin (AST@dSe-AFT) on vestibular toxicity induced by gentamicin (GM) in mice. <b>Methods:</b> Forty-two male ICR mice aged 6-8 weeks were randomly divided into seven groups according to a random number table: control group, GM injury group, natural astaxanthin (AST) protection group (GM+AST group), and four AST@dse-AFT protection groups (GM+AST/NP 0.1 group, GM+AST/NP 1 group, GM+AST/NP 10 group, and GM+AST/NP 100 group), which were given 0.1, 1, 10, and 100 mg/ml AST@dSe-AFT, respectively. The control group did not receive any intervention;the GM injury group was established by intraperitoneal injection of 200 mg/kg GM for 7 consecutive days to construct a vestibular injury model; the GM+AST group received an intratympanic injection of 0.1 ml of 1 mg/ml AST dimethyl sulfoxide solution, while the remaining four groups received intratympanic injections of corresponding concentrations of AST@dSe-AFT. Afterwards, a vestibular injury model was constructed. The vestibular function was evaluated through swimming experiments, balance beam experiments, and rotating rod fatigue instrument experiments. The morphology and number of hair cells in the macula of the utricle and saccule were observed by immunofluorescence staining, and the expression levels of apoptosis-related proteins in the vestibular tissues were analyzed. <b>Results:</b> The behavioral experiments revealed that the balance beam passing time in the GM+AST/NP 10 and GM+AST/NP 100 groups were shorter than that in the GM injury group [(18.8±1.5) and (19.3±1.2) vs (33.9±2.0) s, all <i>P</i><0.05], and the total distance,dwell time and speed of the rotating rod fatigue test were higher than those in the GM injury group [(2.9±0.4), (3.3±0.6), (1.0±0.1) m; (121.6±9.2), (125.7±11.4), (70.9±5.1) s; (30.7±2.4), (31.7±3.0), (17.2±1.4) m/s, respectively, all <i>P</i><0.05]. Immunofluorescence staining results showed that the number of hair cells in the utricle macula in the GM+AST/NP 10 and GM+AST/NP 100 groups were higher than that in the GM injury group (all <i>P</i><0.05). The expression of apoptosis-related proteins Cleaved caspase 3, Cleaved caspase 9, and Cleaved PARP-1 in the GM+AST/NP 10 group was lower than that in the GM injury group (all <i>P</i><0.05). <b>Conclusions:</b> Intratympanic injection of AST@dSe-AFT can antagonize GM-induced vestibular damage, and its protective effect on vestibular function may be related to the inhibition of hair cell apoptosis.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 26","pages":"2218-2226"},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y N Che, X S Zhou, J Q Chen, Z E Wang, L Li, M Huang, L L Xu, J Zhang, H X Liu, Z F Zhang
{"title":"[A case of acute promyelocytic leukemia with NUP98::RARG::LINE-L2a tripartite fusion and the mechanism of resistance to all-trans retinoic acid].","authors":"Y N Che, X S Zhou, J Q Chen, Z E Wang, L Li, M Huang, L L Xu, J Zhang, H X Liu, Z F Zhang","doi":"10.3760/cma.j.cn112137-20250226-00450","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20250226-00450","url":null,"abstract":"<p><p>This study reports a novel case of acute promyelocytic leukemia (APL) characterized by a tripartite fusion gene, NUP98::RARG::LINE-L2a, formed by the rearrangement of nucleoporin 98 (NUP98), retinoic acid receptor gamma (RARG), and long interspersed nuclear element L2a (LINE-L2a). The molecular mechanism underlying the patient's resistance to all-trans retinoic acid (ATRA) is also investigated. The 32-year-old male was admitted to Shandong Provincial Hospital Affiliated to Shandong First Medical University with complaints of \"a 10-day cough and newly detected leukocytosis for one day\". He was initially diagnosed with acute myeloid leukemia (AML) and bronchitis. Fundus hemorrhage was observed on physical examination. Coagulation tests showed elevated D-dimer and prolonged prothrombin time. Bone marrow smears showed 92% abnormal promyelocytes, and flow cytometry indicated an APL immunophenotype. However, the PML::RARA fusion gene formed by the promyelocytic leukemia (PML) gene and the retinoic acid receptor α gene (RARA) was negative by genetic testing, but identified by transcriptome sequencing as the NUP98:: RARG:: LINE-L2a tripartite fusion gene positive.. The patient responded poorly to ATRA-based induction therapy. Upon identifying the tripartite fusion gene, the treatment was switched to idarubicin combined with cytarabine chemotherapy. The patient achieved complete remission and subsequently underwent allogeneic hematopoietic stem cell transplantation. At the most recent follow-up of 16 months post-transplantation(May 2025), the patient remained in continuous remission. Sequence and fusion protein structural analyses revealed that the tripartite fusion leads to truncation of the ligand-binding domain of RARG gene, which is the key molecular mechanism underlying ATRA resistance.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 25","pages":"2120-2123"},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y He, Q Jia, Z Y Zhao, K K Yu, Y T Wang, X Q Kang, L Wang, M X Wang, C B Li
{"title":"[Clinical efficacy of the \"double-strand inverted V-shape\" suture under hip arthroscopy in acetabular labral injuries].","authors":"Y He, Q Jia, Z Y Zhao, K K Yu, Y T Wang, X Q Kang, L Wang, M X Wang, C B Li","doi":"10.3760/cma.j.cn112137-20241218-02872","DOIUrl":"10.3760/cma.j.cn112137-20241218-02872","url":null,"abstract":"<p><p><b>Objective:</b> To compare the efficacy of the \"double-strand inverted V-shape\" vs the \"single-strand looped\" suture techniques to treat acetabular labral injuries under hip arthroscopy. <b>Methods:</b> In this study, clinical data of patients diagnosed with femoroacetabular impingement admitted to the Department of Sports Medicine, Orthopedic Medicine Division, the Chinese PLA General Hospital from June 2018 to July 2022 were collected and analyzed retrospectively. Patients were divided into the \"double-strand inverted V-shape\" (double-strand) and the \"single-strand looped\" (single-strand) groups based on the surgical suture method for the injured labrum. The two groups were compared in terms of the labral injury extent, number and cost of anchors, and preoperative and postoperative outcomes using the visual analog scale (VAS) for pain, modified Harris Hip score (mHHS), and International Hip Outcome Tool (iHOT-12) scores. <b>Results:</b> Fifty-eight patients were included, with 30 in the double-strand group, 20 males and 10 females, aged (37.8±10.2) years, and 28 in the single-strand group, 18 males and 10 females, aged (39.3±12.6) years. All patients underwent surgery successfully, and the patients in the double-strand group and single-strand group were followed-up for [<i>M</i>(<i>Q</i><sub>1</sub>, <i>Q</i><sub>3</sub>)] [36.0(24.0, 36.0) and 30.0(24.0, 36.0) months, respectively. The extent of labral injury 3.5 (3.0, 4.0) vs 2.0 (1.5, 2.4) h], the number of anchors [4.0 (4.0, 4.3) vs 3.0 (3.0, 4.0) pins], and the cost of the anchors [7 084 (6 916, 8 603) vs 5 061 (5 061, 6 748) yuan] in the double-strand group were all higher than those of the single-strand group (all <i>P</i><0.001), but the number of anchors/injury extent [1.2 (1.1, 1.3) vs. 1.5 (1.5, 2.0) pins/h] and anchor cost/injury extent[2 092 (1 949, 2 305) vs. 2 531 (2 531, 3 374) yuan/h] were lower (both <i>P</i><0.001). There was no statistical significance in the differences of preoperative and postoperative VAS, mHHS, and iHOT scores between the double-strand group and the single-strand group, as well as in the differences of the changes in VAS, mHHS, and iHOT scores before and after surgery (all <i>P</i>>0.05). <b>Conclusion:</b> The \"double-strand inverted V-shape\" suture technique for acetabular labral injuries under hip arthroscopy can achieve clinical outcomes similar to the \"single-strand looped\" suture technique while reducing anchor use and costs under same injury extent, and providing better economic benefits.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 ","pages":"2090-2095"},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144286637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Efficacy of puncture-based limited incision capsulotomy under hip arthroscopy for femoroacetabular impingement].","authors":"H S Zhang, C Liu, S Chen, Z H Liu","doi":"10.3760/cma.j.cn112137-20241220-02902","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20241220-02902","url":null,"abstract":"<p><p><b>Objective:</b> To explore the clinical effect of puncture-based limited incision capsulotomy under hip arthroscopy in the treatment of femoroacetabular impingement (FAI). <b>Methods:</b> A retrospective analysis was conducted on the data of patients with FAI who underwent hip arthroscopy surgery at Cangzhou Central Hospital from January 2020 to January 2023. All patients were divided into two groups based on capsular management during hip arthroscopy: the T-shaped capsulotomy group (TS group) and the puncture limited capsulotomy group (PL group). The TS group underwent traditional T-shaped capsulotomy via an outside-in approach, while the PL group received cannula-guided puncture and limited longitudinal capsulotomy via an inside-out approach. By comparing the incidence of postoperative complications, total surgical time (TOT), capsule suturing time (CST), CST/TOT, visual analog scale (VAS) pain score, modified Harris hip joint score (mHHS), nonarthritic hip score (NAHS), and international hip outcome tool-12 (iHOT-12) during preoperative and postoperative period at 6 months and 1 year follow-up between TS and PL group, the clinical efficacy in the two groups was evaluated. <b>Results:</b> A total of 82 patients were enrolled in this study, 30 males and 52 females with a mean age of (46.0±11.9) years; there were 32 cases (32 hips) in TS group and 50 cases (50 hips) in PL group. The TOT[(62.2±7.9) vs (50.2±7.2)min], CST[17.0(15.0, 22.8) vs 9.0(7.8, 10.0) min], and CST/TOT ratios [29.0%(22.5%, 34.8%) vs 17.5%(14.8%, 21.0%)] in TS group were all significantly higher than those in PL group (all <i>P</i><0.001). Complication incidence rate in the TS and PL group was comparable [15.6% (5 cases) vs 14.0% (7 cases), <i>P</i>=0.840]. There was no significant differences in preoperative VAS, mHHS, NAHS, and iHOT-12 scores between the TS and PL group (all <i>P</i>>0.05). Both groups demonstrated progressive pain VAS reduction at 6 months and 1 year after the operation (all <i>P</i><0.05 within groups), with the PL group exhibiting lower 6-month VAS (<i>P</i><0.05). Functional scores (mHHS, NAHS, iHOT-12) improved progressively at 6 months and 1 year after the operation in both groups (all <i>P</i><0.05 within groups). At 6 months, the PL group showed superior functional scores (all <i>P</i><0.05), but no inter-group differences remained at 1 year (all <i>P</i>>0.05). <b>Conclusion:</b> The hip arthroscopy technique of puncture-based limited incision capsulotomy for treating FAI demonstrates favorable clinical outcomes, significantly reduces operative time, enhances surgical efficiency, and does not increase the incidence rate of surgical complications.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 25","pages":"2096-2102"},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Q H Meng, C Sun, M S Gao, N C Cheng, Y S Zheng, S Q Shang, J Lin, C B Zhao
{"title":"[Clinical features and prognosis of patients with peripheral neuropathy with systemic light chain amyloidosis].","authors":"Q H Meng, C Sun, M S Gao, N C Cheng, Y S Zheng, S Q Shang, J Lin, C B Zhao","doi":"10.3760/cma.j.cn112137-20241231-02980","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20241231-02980","url":null,"abstract":"<p><p>The clinical data and prognosis of 6 patients with systemic light chain amyloidosis-related peripheral neuropathy admitted to Huashan Hospital Affiliated to Fudan University from June 2019 to January 2024 were analyzed retrospectively, and discussed.The patients were from 48 to 70 (58±9) years, including 4 males and 2 females. Among the initial symptoms, 4 cases had both lower limb sensory abnormalities, 1 case had both upper limb numbness, pain, weakness, 1 case had swallowing disorders, 5 cases had pain and autonomic symptoms, 6 cases had weight loss, 6 cases had heart involvement, mainfested as chest tightness, shortness of breath, and 3 patients had kidney involvement, manifested as asymptomatic proteinuria. Four cases had light chain type λ, 1 case had λ+κ and i case had κ. Five cases underwent lumbar puncture with protein cell separation and CSF protein was (1.00±0.21) g.Electrophysiological examination was performed in all 6 patients, suggesting multiple peripheral nerve damage involving motor and sensory nerves and mainly axonal involvement.Four cases (4/5) had positive intestinal biopsies; 1 (1/3) cases had positive nerve biopsy; 1 (1/1) case had positive skin biopsy and 1 (0/1) had negative fat biopsy; 5 (0/5) had bone marrow biopsy, with negative Congo red staining. All 6 patients underwent chemotherapy, with only 1 improving, 3 experiencing gradually worsening symptoms, and 2 dying. Multiple peripheral nerve axonal damage and autonomic nerve involvement are characteristics of systemic light chain amyloidosis peripheral neuropathy.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 25","pages":"2116-2119"},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[New insights into the role of testosterone in improving glucose and lipid metabolism in adult males].","authors":"J F Mao, X Y Wu","doi":"10.3760/cma.j.cn112137-20241211-02800","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20241211-02800","url":null,"abstract":"<p><p>Testosterone plays a crucial impact on male growth and development, sexual function, muscle mass, and mental health. In recent years, the role of testosterone in regulating energy metabolism via multiple targets has increasingly drawn attention. It can not only enhance insulin sensitivity but also promote lipolysis, thus offering novel insights into the prevention and treatment of diabetes mellitus, fatty liver, and obesity. Timely testosterone supplementation in adult male patients with type 2 diabetes mellitus and obesity may bring significant metabolic benefits.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 25","pages":"2033-2036"},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Influence of surgeon's dominant versus nondominant hand manipulation on hip arthroscopy].","authors":"Q H Jin, J H Li, S Y Sha, Y Liu, Q F Yin","doi":"10.3760/cma.j.cn112137-20241231-02975","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20241231-02975","url":null,"abstract":"<p><p>This study aimed to investigate surgeons' subjective perceptions of handedness effects on hip arthroscopy through questionnaire surveys, and to evaluate the objective outcomes of handedness effects by retrospective research. The questionnaire targeted hip joint surgeons from the Chinese Society of Sports Medicine, while the clinical review analyzed 175 consecutive hip arthroscopy procedures (from January 2019 tp December 2021) performed by a single right-handed surgeon at Shandong University Second Hospital. Of the patients, there were 83 males and 92 females with a mean age of (38.0±13.0) years. The patients were divided into dominant-hand (<i>n</i>=86) and non-dominant-hand (<i>n</i>=89) groups for comparison of operative parameters and outcomes. The survey (159 participants with a response rate of 100%) revealed that 82.39% (131/159) perceived superior proficiency with dominant hand, 61.64% (98/159) of the surgeons believed that the dominant hand for operation could yield better early results, while 50.94% (81/159) reported equivalent long-term results. Clinical data demonstrated superior median fluency scores [4.0(4.0, 5.0) vs 3.0(3.0, 4.0), <i>P</i><0.001] and shorter operation time [(95.4±15.6) vs (111.4±19.6) minutes, <i>P</i><0.001] in dominant-hand procedures. However, no significant difference was found in surgical accuracy or 1-year postoperative outcomes between the two groups (all <i>P</i>>0.05). The findings indicate that while surgeons' non-dominant hand use may compromise surgical fluency and operation time, it does not significantly affect surgical accuracy or clinical outcomes.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 25","pages":"2112-2115"},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Expert consensus on clinical practice of outside-in longitudinal capsulotomy in hip arthroscopy].","authors":"","doi":"10.3760/cma.j.cn112137-20250321-00696","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20250321-00696","url":null,"abstract":"<p><p>The outside-in longitudinal capsulotomy is an emerging and appealing technique in hip arthroscopy. This technique has its unique features in portal establishment and capsular incision, differing from the traditional inter-portal capsulotomy. Although its clinical use is becoming increasingly popular, there is no consensus in clinical practice. The Hip Joint and Spine Group of the Sports Medicine Branch of the Chinese Medical Association and Hip joint Group of the Sports Medicine Branch of the Chinese Medical Doctor Association initiated this project to reach an expert consensus using a modified Delphi method through literature analysis and expert discussion. This consensus finally gives 14 recommendations covering the definition, indications, key step of capsulotomy, capsular management, postoperative rehabilitation and the advantages and disadvantages of this technique, aiming to provide guidance and reference for the standardized application of the outside-in longitudinal capsulotomy.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 25","pages":"2048-2057"},"PeriodicalIF":0.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}