Zhonghua yi xue za zhi最新文献

{"title":"[Expert consensus on the assessment of brain injury and determination of brain death during extracorporeal membrane oxygenation support (2025 edition)].","authors":"","doi":"10.3760/cma.j.cn112137-20241231-02973","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20241231-02973","url":null,"abstract":"<p><p>Extracorporeal membrane oxygenation (ECMO) serves as a pivotal life-support modality. However, the associated increased brain injury and its prognosis and outcome have raised significant concern. To address these challenges, an interdisciplinary task force comprising neurologists, neurosurgeons, intensivists, emergency physicians, anesthesiologists, pediatricians, and healthcare administrators collaboratively developed the \"Expert consensus on the assessment of brain injury and determination of brain death during extracorporeal membrane oxygenation support\". Utilizing a modified Delphi methodology and the Oxford Centre for Evidence-Based Medicine 2009 criteria, and guided by 29 clinical issues, the consensus analyzed and discussed 4 themes, including an overview of ECMO, brain injury during ECMO, brain function assessment during ECMO, and brain death determination during ECMO. A total of 8 recommendations were put forward, aiming to provide help and guidance for clinicians and improve the prognosis and outcome of patients.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 ","pages":"1331-1346"},"PeriodicalIF":0.0,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Practice guidelines for diagnosis, treatment, and prevention of tuberculosis in patients with rheumatic disease].","authors":"","doi":"10.3760/cma.j.cn112137-20250208-00281","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20250208-00281","url":null,"abstract":"<p><p>China is a high-burden country for tuberculosis (TB), and patients with rheumatic diseases (RD) are at significantly increased risk of TB infection and progression. Currently, there are no comprehensive clinical practice guidelines providing recommendations for the screening, diagnosis, treatment, and prevention of TB in RD patients. To address this issue, the Collaborative Group for TB Prevention and Control in Patients with RD in China, in collaboration with the Chinese Society of Clinical Epidemiology and Evidence-Based Medicine, Chinese Society of Rheumatology, Chinese Society of Tuberculosis and Chinese Society of Infectious Diseases, developed evidence-based recommendations. These were formulated using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology and the Reporting Items for Practice Guidelines in Healthcare (RIGHT) standards. Based on the 14 clinical questions formed from the preliminary research, including: (1) which RD patients need to be screened for TB, (2) how to select the screening methods for TB, (3) whether to conduct re-screening for latent tuberculosis infection (LTBI) after the initial screening is negative, (4) how to diagnose and differentiate RD patients with active tuberculosis (ATB), (5) the indications and courses of empirical anti-TB treatment for RD patients suspected of ATB, (6) how to diagnose drug-resistant TB in RD patients with ATB, (7) the characteristics and management of subclinical TB in RD patients with ATB, (8) the recommended treatment regimens and courses for TB in RD patients, (9) the interaction between anti-TB drugs and RD treatment drugs and how to choose alternative regimens, (10) how to handle adverse drug reactions during anti-TB treatment in RD patients, (11) how to evaluate the effectiveness of anti-TB treatment in RD patients, (12) the indications for initiating tuberculosis preventive treatment (TPT) in RD patients, (13) the recommended regimens and courses for TPT in RD patients, (14) the protection period of TPT and whether to repeat it, detailed evidence-based recommendations were provided, aiming to offer decision support for clinical practice.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 ","pages":"1303-1321"},"PeriodicalIF":0.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Efficacy and safety of stereoelectroencephalography-guided 3D radiofrequency thermocoagulation for the treatment of drug-resistant medial temporal lobe epilepsy with hippocampal sclerosis].","authors":"L Jin, D X Zhi, Y F Yang, S C Chen, T R Wang, D Lu, Y Z Shan","doi":"10.3760/cma.j.cn112137-20240925-02179","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20240925-02179","url":null,"abstract":"<p><p><b>Objective:</b> To evaluate the efficacy and safety of stereotactic electroencephalography (SEEG)-guided 3D radiofrequency thermocoagulation (RF-TC) in the treatment of drug-resistant mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE-HS). <b>Methods:</b> This study was a randomized controlled trial. The patients with drug-resistant mTLE-HS recruited from Xuanwu Hospital, Capital Medical University between August 2019 and October 2022 were prospectively enrolled. The patients were randomly assigned to receive either anterior temporal lobectomy (ATL) or RF-TC treatment using a variable block randomization method. All patients were assessed both preoperatively and 1 year postoperatively. The postoperative outcomes in terms of epileptic seizure results, visual field defects, and surgery-related complications were compared between the two groups. <b>Results:</b> A total of 38 patients were included, 19 males and 19 females, with an average age of (28.3±6.9) years. There were 20 cases in the ATL group and 18 cases in the RF-TC group. There was no statistically significant difference in age [(28.5±5.7) vs (28.2±8.1), <i>P</i>=0.848] or gender distribution (7/20 vs 12/18, <i>P</i>=0.103) between the both groups. At the 1-year follow-up post-surgery, there was no statistically significant difference in the proportion of patients achieving Engel Class Ⅰfor epileptic seizure results between the ATL group and the RF-TC group (17/20 vs 13/18, <i>P</i>=0.438). The proportion of patients in the ATL group who developed visual field defects was higher than that in the RF-TC group (15/20 vs 3/18, <i>P</i><0.010). No severe adverse events were observed in both groups. <b>Conclusion:</b> The epilepsy control efficacy of SEEG-guided 3D RF-TC is comparable to that of traditional surgery, while offering superior outcomes in visual field preservation.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 11","pages":"827-833"},"PeriodicalIF":0.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Expert consensus on percutaneous spinal cord stimulation for the treatment of painful diabetic neuropathy(2024 edition)].","authors":"","doi":"10.3760/cma.j.cn112137-20240821-01924","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20240821-01924","url":null,"abstract":"<p><p>Spinal cord stimulation (SCS) has been used for decades in clinical treatment of chronic pain such as painful diabetic neuropathy, and its efficacy and safety have been widely confirmed. The selection of appropriate patients, professional SCS implantation technology, precise postoperative programming, and regular follow-up are the basis for curative effect, which puts higher requirements on the theoretical knowledge and practical skills of clinicians. To address this need, the Physicians Branch of the Department of Pain of the Chinese Medical Doctor Association and the Professional Committee of Neuroregulation of the Chinese Medical Doctor Association organized expert clinicians in relevant fields to develop this consensus on patient selection, preoperative planning, intraoperative techniques, postoperative care, and prevention and treatment of common adverse reactions, aiming to enhance the quality of SCS therapy for patients with painful diabetic neuropathy.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 11","pages":"805-813"},"PeriodicalIF":0.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Expert consensus on disease-modifying therapy for Alzheimer's disease].","authors":"","doi":"10.3760/cma.j.cn112137-20250304-00512","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20250304-00512","url":null,"abstract":"<p><p>Alzheimer's disease (AD) poses a significant challenge to China's aging population, and treatment is now comprehensively shifting toward disease-modifying therapy (DMT). By targeting core pathophysiological mechanisms, DMT seeks to alter the natural progression of AD. As an emerging therapeutic paradigm, there is an urgent need for expert consensus to standardize the clinical use of DMT drugs in AD. This consensus systematically reviews both clinical practice and research advancements related to DMT for AD, including its target populations, contraindications and high-risk groups, pre-treatment evaluation procedures, administration methods and durations, efficacy assessments, and adverse event monitoring. It presents 17 recommendations to guide the clinical application of DMT in AD.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 ","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143664719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Impact of bundle therapy for sepsis on patient prognosis and its current implementation status].","authors":"Y F Ding, X Q Li, X Z Li, G J Chen, C W Pan, Y Yang, Y Z Huang, J F Xie","doi":"10.3760/cma.j.cn112137-20240807-01809","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20240807-01809","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the correlation between the completion rate of sepsis 1-hour bundle therapy and the prognosis of patients with sepsis or septic shock, as well as to survey the awareness and implementation status of sepsis bundle therapy among medical staff in intensive care unit (ICU). <b>Methods:</b> The medical records of patients with sepsis or septic shock admitted to the Department of Critical Care Medicine of Zhongda Hospital, Southeast University from January 2020 to January 2024 were analyzed retrospectively. The patients were divided into two groups based on whether the bundle therapy was completed. The correlation between the completion of sepsis bundle therapy and the 28-day mortality rate of patients was analyzed. From August 3 to 20, 2023, a survey on the awareness and implementation status of sepsis bundle therapy among ICU medical staff in China was conducted using the WJX (Questionnaire Star) form. <b>Results:</b> A total of 712 patients with sepsis or septic shock were included in the analysis, comprising 470 males and 242 females, with a mean age of (66.92±16.36) years. Among them, 575 (80.8%) were in the bundle therapy completion group, and 137 (19.2%) were in the non-completion group. There were no statistically significant differences in age, gender, and disease severity between the two groups (<i>P</i>>0.05). However, the 28-day mortality rate was lower in the completion group compared to that in the non-completion group (28.7% vs 39.4%, <i>P</i>=0.015). Completion of bundle therapy was associated with a lower mortality risk in patients with sepsis or septic shock (<i>OR</i>=0.358, 95%<i>CI</i>: 0.216-0.595). The survey part included 1 339 ICU medical staff from 680 hospitals across 32 provinces, autonomous regions, and municipalities in China, with a valid response rate of 99.0% (1 325/1 339). Among them, 92.5% (1 226/1 325) of the ICU medical staff claimed to have mastered the diagnostic criteria and treatment measures of sepsis bundle therapy, but in reality, only 25.2% (334/1, 325) of the ICU medical staff could fully grasp the relevant knowledge. The surveyed ICU medical staff focused their suggestions for improving the completion rate of sepsis bundle therapy on knowledge training (86.6%, 1 148/1 325), quality supervision and feedback (79.8%, 1 057/1 325), and improvement of information-based data capture (72.2%, 957/1 325). <b>Conclusions:</b> The completion rate of sepsis bundle therapy is correlated with the 28-day mortality rate of patients with sepsis or septic shock. The mastery of sepsis bundle therapy by ICU medical staff is not satisfactory.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 11","pages":"820-826"},"PeriodicalIF":0.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis of the correlation between serum magnesium levels and ineffective recanalization after mechanical thrombectomy in patients with acute large vessel occlusion stroke].","authors":"Z J Ou, C K Zhong, Y Q Wang, J P Chen, G D Xiao, Y J Cao, G J Zhai","doi":"10.3740/cma.j.cn112137-20240831-02031","DOIUrl":"https://doi.org/10.3740/cma.j.cn112137-20240831-02031","url":null,"abstract":"<p><p>Three hundred and twelve acute large vessel occlusion stroke patients who underwent mechanical thrombectomy at Changshu Hospital of Traditional Chinese Medicine, Suzhou Ninth People's Hospital, and the Second Affiliated Hospital of Soochow University from July 2016 to December 2023 were retrospectively collected. The patients were divided into effective recanalization group(mRS<3) and ineffective recanalization (mRS≥3) group based on 90-day modified Rankin scale(mRS) scores. Serum magnesium levels were categorized into tertiles: T1(Mg²⁺≤0.75 mmol/L), T2(0.75 mmol/L<Mg²⁺≤0.84 mmol/L) and T3(Mg²⁺>0.84 mmol/L), and the relationship between serum magnesium levels and ineffective recanalization was evaluated. Multivariable logistic regression model was used to analyze the related factors of ineffective recanalization. Low serum magnesium levels (Mg²⁺≤0.75 mmol/L) (<i>OR</i>=1.94, 95%<i>CI</i>: 1.03-3.64), previous stroke history (<i>OR</i>=2.22, 95%<i>CI</i>: 1.04-4.75), pre-procedural hyperglycemia (<i>OR</i>=1.16, 95%<i>CI</i>: 1.05-1.29), and lower Alberta stroke early CT scores(ASPECTS) (<i>OR</i>=0.38, 95%<i>CI</i>: 0.20-0.72) were related risk factors for ineffective recanalization after mechanical thrombectomy. The proportion of patients with mRS scores of≥3 was highest in the T1 group [65.1% (71/109)] and lowest in the T3 group [51.0% (49/96)]. Serum magnesium level is closely related to functional prognosis of patients.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 11","pages":"834-838"},"PeriodicalIF":0.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Efficacy and safety of endoscopic direct-vision appendicitis therapy in patients with acute appendicitis].","authors":"M Y Li, Y Liang, Y D Feng, J Liu, Y N Zhu, R H Shi","doi":"10.3760/cma.j.cn112137-20241203-02720","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20241203-02720","url":null,"abstract":"<p><p><b>Objective:</b> To analyse the efficacy and safety of endoscopic direct-vision appendicitis therapy (EDAT) in patients with acute appendicitis. <b>Methods:</b> The clinical data of patients diagnosed with acute appendicitis and underwent surgical treatment from May 2023 to July 2024 at Zhongda Hospital of Southeast University were analysed retrospectively. The patients were divided into EDAT group (41 cases) and laparoscopic appendectomy (LA) group (630 cases) according to the surgical methods. After 1∶2 propensity score matching (PSM) based on general baseline information, Alvarado score and underlying diseases, the perioperative period and prognosis indicators were compared between the 2 groups. The deadline for follow-up was October 30, 2024. <b>Results:</b> A total of 123 patients were included after PSM, 41 patients in EDAT group, including 21 males and 20 females, aged [<i>M</i> (<i>Q</i>₁, <i>Q</i>₃)] 55 (37, 61) years; and 82 patients in LA group, including 41 males and 41 females, aged 50 (35, 60) years. A total of 366(221, 492) days were followed up. The operative time [ (38.7±22.3) vs (54.8±16.2) min], postoperative intestinal function recovery time [(2.5±1.3) vs (21.8±5.0) h], duration of antibiotic use [2 (2, 2) vs 3 (3, 4) d] and hospitalisation days [2 (1, 2) vs 3(2, 4) d] in EDAT group were shorter than those in LA group; postoperative visual analogue scale (VAS) score at 6 hours [(3.2±1.3) vs (5.5±1.2) scores] was lower than that in LA group; the proportion of patients with intraoperative bleeding >20 ml [0 vs 61% (50/82)] and proportion of painkiller use [7.3% (3/41) vs 69.5% (57/82)] were lower than those of LA group (all <i>P</i><0.001). The rate of postoperative recurrence in EDAT group was higher than that in LA group [4.9% (2/41) vs 0, <i>P</i>=0.035]. <b>Conclusion:</b> EDAT is effective and safe in treating patients with acute appendicitis, but patients are at risk of recurrence.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 11","pages":"814-819"},"PeriodicalIF":0.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis on the efficacy and safety of transvenous lead extraction in the treatment of patients with cardiac lead perforation].","authors":"C Z Yuan, H Y Qiao, F Ze, C C Wu, J B Duan, X Zhou, X B Li","doi":"10.3760/cma.j.cn112137-20240905-02054","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20240905-02054","url":null,"abstract":"<p><p>To investigate the efficacy and safety of transvenous lead removal (TLR) in the treatment of patients with cardiac lead perforation. The case data of 82 patients who underwent TLR for lead perforation at Peking University People's Hospital from January 2014 to June 2024 were retrospectively analyzed. The patients' age was (68.0±12.6) years, with 38 males and 44 females. Clinical symptoms of patients with lead perforation, characteristics of the perforated leads, operation success rate, complication incidence, tools used in TLR, and follow-up situation were analyzed. Clinical symptoms related to lead perforation were present in 80.5% (66/82) of patients, with chest pain being the most common [57.3%(47/82)]. Among the perforated leads, 6.1%(5/82) penetrated outside the pericardium, 58.5%(48/82) were delayed perforations, 65.9%(54/82) were active fixation leads, 78.0%(64/82) of the perforation sites were at the right ventricular apex, and 76.8%(63/82) had abnormal programmed lead parameters. The diagnosis of all lead perforations was confirmed by imaging examinations. Eight high-risk patients received percutaneous dry pericardiocentesis before surgery. Eighty-two patients underwent TRL surgery successfully, and no major complications occurred. Among the perforated leads, 57.3% (47/82) of the perforated leads were successfully removed manually. New leads were implanted in 91.5% (75/82) of patients during the same operation. Follow-up was conducted until August 2024, with a total follow-up duration of (5.1 ± 2.7) years. During the follow-up period, a total of 7 patients reached the end events, including 5 deaths and 2 patients who underwent TLR again. In experienced centers, TLR is a safe and effective treatment approach for cardiac implantable electronic devices lead perforation. Prophylactic dry pericardiocentesis can be used as an unconventional option.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 11","pages":"839-843"},"PeriodicalIF":0.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Expert consensus on the out-of-hospital management of myelosuppression associated with oncological treatment (2025 edition)].","authors":"","doi":"10.3760/cma.j.cn112137-20241029-02425","DOIUrl":"https://doi.org/10.3760/cma.j.cn112137-20241029-02425","url":null,"abstract":"<p><p>Myelosuppression is a common hematological side effect of oncological treatment, mainly including neutropenia, thrombocytopenia and anemia. Due to the delay in its clinical manifestation, a well-established out-of-hospital management system can help clinicians better prevent and manage the myelosuppression associated with oncology treatment and ensure the effectiveness and safety of antitumor therapy. This consensus focuses on a detailed compilation and summary of the definition and grading of myelosuppression associated with oncological treatment, the principles of out-of-hospital management, the management process and management methods, develops a risk stratification assessment table for oncology treatment-related myelosuppression, and puts forward 8 recommendations based on the risk stratification, which is aimed at providing medical workers with a reference plan for the out-of-hospital management of myelosuppression associated with oncological treatment.</p>","PeriodicalId":24023,"journal":{"name":"Zhonghua yi xue za zhi","volume":"105 11","pages":"793-804"},"PeriodicalIF":0.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}