Zhongguo gu shang = China journal of orthopaedics and traumatology最新文献

{"title":"[Application and prospects of medical-engineering integration technology in rehabilitation following total knee arthroplasty].","authors":"Xilin Gao, Aifeng Liu, Chao Zhang, Ping Wang, Minshan Feng, Bifeng Fu","doi":"10.12200/j.issn.1003-0034.20251009","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20251009","url":null,"abstract":"<p><p>This paper systematically reviews the relevant literature from the China National Knowledge Infrastructure (CNKI) and Web of Science databases, focusing on the three key components of rehabilitation after total knee arthroplasty (TKA):evaluation, intervention, and management. It summarizes the progress of medical-engineering integration technologies. Quantitative assessment methods, such as gait analysis, enhance the objectivity and continuity of functional evaluations but are constrained by issues like inconsistent data standards. Rehabilitation robotics offers controllability and traceability, making it promising for personalized treatment plans, though challenges related to equipment costs and scene adaptation remain. AI-assisted decision-making systems integrate multi-source information for treatment recommendations, improving decision-making efficiency and accuracy, but their effectiveness is limited by dependence on data quality. Immersive virtual reality (VR) training enhances engagement, improves proprioception, and helps manage pain, but its effectiveness is influenced by device limitations and individual tolerance. Remote rehabilitation systems significantly improve the continuity of management, yet their widespread implementation faces challenges, including low acceptance among older adults and inadequate infrastructure. Current research hotspots are mainly focused on device development, data integration and interoperability, and strengthening clinical evidence. The authors suggest that future efforts should strengthen interdisciplinary collaboration and conduct high-quality clinical research to establish a generalizable intelligent precision rehabilitation model.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 1","pages":"105-12"},"PeriodicalIF":0.0,"publicationDate":"2026-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146150888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Finite element biomechanical analysis of coronal alignment correction in unicompartmental knee arthroplasty for severe varus deformity].","authors":"Lizhi Han, Pei Zhang, Hongyu Zhang, Yong Zhang, Zhenfei Ding, Huanyu Li, Wenju Chang, Lijia Pei, Xinshe Zhou, Heng Zhang, Jianzhong Guan","doi":"10.12200/j.issn.1003-0034.20250620","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20250620","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To investigate the effects of different correction angles of the coronal lower limb alignment (represented by the hip-knee-ankle, HKA ) on the stress of prostheses and ligaments in patients with severe genu varum undergoing unicompartmental knee arthroplasty (UKA), and to clarify the optimal reconstruction strategy for postoperative coronal alignment.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Based on the computed tomography (CT) and full-ength lower limb X-ray data of 12 patients with severe genu varum (HKA angle:15°to 20°), individualized three-dimensional finite element models were established. By adjusting the HKA angle, four types of UKA correction models were constructed with HKA angles of 0° (neutral), 3°, 6°, and 9°of varus. Seven physiological knee postures (erect, varus, valgus, internal rotation, external rotation, flexion, and hyperextension) were simulated, with a vertical load of 750 N and a bending moment of 7.5 N·m applied. The maximum stress values of the femoral prosthesis, tibial prosthesis, polyethylene insert, medial/lateral collateral ligaments(MCL/LCL), and anterior/posterior cruciate ligaments(ACL/PCL) were calculated. The Mann-Whitney U test was used to analyze the biomechanical differences among different correction angles and postures.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 48 groups of models were established (4 HKA angles×12 patients× 1 prosthesis type). In terms of prosthetic stress, the prosthesis bore the maximum stress when the HKA angle was corrected to 9° of varus, which was significantly higher than those at other angles (&lt;i&gt;P&lt;/i&gt;&lt;0.01). For soft tissue stress, the 6° model exhibited the largest number of combinations with maximum soft tissue stress (10 combinations), which was significantly higher than that of the 3° model (1 combination);the 0° and 9° models showed 8 and 9 combinations, respectively. The differences in maximum stress values of the same model components among different varus models and across different postures were statistically significant (&lt;i&gt;P&lt;/i&gt;&lt;0.01). The 9° varus model presented peak prosthetic stress in 3 out of the 7 postures (1 posture each for the 0° and 6° models, and 2 postures for the 3° model), with the most significant effect observed in the valgus posture. The lateral compartment stress was the highest in the 0° model and the lowest in the 3° model.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Finite element analysis demonstrated that for patients with severe genu varum undergoing UKA, correcting the postoperative HKA angle to approximately 3° of varus results in an optimal stress distribution across the prosthesis-ligament system, and the soft tissue load is closer to the physiological state. The pursuit of a completely neutral alignment (0°) or residual large-angle varus (≥6°) should be avoided. The former increases lateral compartment stress and accelerates joint degeneration, while the latter significantly elevates the stress load on the prosthesis and some","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 1","pages":"52-60"},"PeriodicalIF":0.0,"publicationDate":"2026-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146149896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Impact of different exercise modalities on electrophysiology and soft tissue function following lumbar discectomy].","authors":"Chengyu Huang, Kai Chen, Zibo Gao, Honglin Liu, Fangzheng Lin, Yang Xiao, Xiaolong Zeng, Yu Hou, Dingkun Lin, Yongjin Li","doi":"10.12200/j.issn.1003-0034.20251039","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20251039","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To investigate the mechanism underlying the effects of supine air straight leg pushing on muscle group regulation and musculoskeletal balance in patients following transforaminal endoscopic lumbar discectomy (TELD).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Thirty-eight patients who underwent transforaminal endoscopic lumbar discectomy(TELD) between July 2024 and January 2025 were selected and divided into a exercise group and a &lt;i&gt;Feiyan&lt;/i&gt; exercise group according to different postoperative exercise methods, with 19 patients in each group. Both groups received 4 weeks of postoperative rehabilitation exercises after suture removal at 2 weeks postoperatively. The exercise group included 19 patients:12 males and 7 females;9 patients on the left side and 10 patients on the right side;aged from 25 to 61 years old with an average of (40.37±10.40) years old;10 patients with surgical segments at L&lt;sub&gt;4,5&lt;/sub&gt; and 9 patients at L&lt;sub&gt;5&lt;/sub&gt;S&lt;sub&gt;1&lt;/sub&gt;;body mass index (BMI) ranging from 19.72 to 27.68 kg·m&lt;sup&gt;-2&lt;/sup&gt; with a mean of (23.48±2.46) kg·m&lt;sup&gt;-2&lt;/sup&gt;;they received supine straight-leg kicks exercises. The &lt;i&gt;Feiyan&lt;/i&gt; exercise group included 19 patients:16 males and 3 females;9 patients on the left side and 10 patients on the right side;aged from 25 to 67 years old with a mean of (40.16±10.86) years old;11 patients with surgical segments at L&lt;sub&gt;4,5&lt;/sub&gt; and 8 patients at L&lt;sub&gt;5&lt;/sub&gt;S&lt;sub&gt;1&lt;/sub&gt;;BMI ranging from 18.43 to 29.28 kg·m&lt;sup&gt;-2&lt;/sup&gt; with a mean of (24.49±2.88) kg·m&lt;sup&gt;-2&lt;/sup&gt;;they received &lt;i&gt;Feiyan&lt;/i&gt; exercises. The visual analogue scale (VAS) and Oswestry disability index (ODI) were compared between the two groups before exercise and 4 weeks after exercise. The maximal voluntary contraction (MVC), root mean square (RMS), integral of the EMG signal (INT), mean power frequency (MPF), and RMS as a percentage of maximal voluntary contraction (RMS/MVC value, %MVC) of the erector spinae, rectus abdominis, vastus medialis, vastus lateralis, and gastrocnemius on the affected side were compared between the two groups before and after exercise. Additionally, the muscle oscillation frequency (F value), dynamic stiffness (S value), and logarithmic decrement of a muscle's natural oscillation (D value) of the erector spinae, rectus abdominis, vastus medialis, vastus lateralis, and gastrocnemius on the affected side were compared between the two groups before and after exercise.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;After exercise, the VAS score of the exercise group was lower than that before exercise;the ODI scores of both groups after exercise were lower than those before exercise, with statistically significant differences (&lt;i&gt;P&lt;/i&gt;&lt;0.05). There was no statistically significant difference in the VAS score of the &lt;i&gt;Feiyan&lt;/i&gt; exercise group between after and before exercise (&lt;i&gt;P&lt;/i&gt;&gt;0.05). After exercise, the VAS and ODI scores of the exercise group were lower than those of the &lt;i&gt;Feiyan&lt;/i&gt; exercise group, ","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 1","pages":"21-32"},"PeriodicalIF":0.0,"publicationDate":"2026-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146150043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Visualization analysis of hydrogel spine research in the Web of Science core collection database].","authors":"Bo Peng, Ruxing Liu, Jiahao Hu, Yi Feng, Yongfeng Wang, Tao Zhang, Xuanjun You, Chaojian Xu","doi":"10.12200/j.issn.1003-0034.20231071","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20231071","url":null,"abstract":"<p><strong>Objective: </strong>To summarize research hotspots and predict future trends by conducting a bibliometric analysis of English literature in the field of hydrogels for spinal applications over the past decade.</p><p><strong>Methods: </strong>Retrieve the English literature included in the Web of Science core collection database from 2012 to 2022, analyze the literature using Citespace 6.1.R6, and draw a visual graph.</p><p><strong>Results: </strong>A total of 84 articles were included, and the number of publications has been increasing year by year. The United States was the country with the highest number of publications, with David Eglin as the author and Univ Delaware as the institution with the highest number of publications, forming 10 meaningful clusters. The current research hotspots were the treatment of intervertebral disc degeneration, repair of the dura mater, and recovery after spinal cord injury.</p><p><strong>Conclusion: </strong>In recent ten years, the research of hydrogel in the field of spine is very popular. It is predicted that the future research in the field of hydrogel spine will continue to deepen under the exploration of disc, 3D printing, cell, chondrocyte transplantation, gene expression and horn structure.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 1","pages":"85-94"},"PeriodicalIF":0.0,"publicationDate":"2026-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146150451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Research status and progress of daytime total shoulder arthroplasty].","authors":"Jun-Rong Chen, Long Chen, Sen-Lei Li, Li Sun","doi":"10.12200/j.issn.1003-0034.20240804","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20240804","url":null,"abstract":"<p><p>Total shoulder arthroplasty(TSA) is primarily used for treating severe shoulder injuries or diseases and has been shown to effectively improve shoulder function. With the expansion of TSA indications and an aging population, the demand for TSA continues to grow. To address this demand and alleviate the economic burden on patients, many countries have adopted the day surgery model for TSA, accompanied by extensive research and discussions on its safety and feasibility. This paper systematically reviews the safety, patient inclusion and exclusion criteria, implementation processes, and perioperative management strategies for TSA day surgery. Based on an analysis of relevant literature from domestic and international sources, the findings indicate that TSA day surgery, when preceded by appropriate patient screening, can safely replace traditional inpatient care. Furthermore, it could significantly reduce hospitalization durations, lower treatment costs, and optimize the utilization of medical resources. However, in clinical practice, there is still a lack of standardized protocols for patient selection criteria and perioperative management strategies. As China's aging population intensifies, TSA day surgery presents promising application prospects. Nevertheless, the development of day surgery in China lags behind that of other countries, and research on TSA day surgery remains in its early stages. Moving forward, research and clinical practices tailored to China's specific needs should be prioritized. Practical clinical operation guidelines must be established to facilitate the widespread adoption and standardized implementation of TSA day surgery, ultimately providing patients with higher-quality and safer medical care.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"38 12","pages":"1282-8"},"PeriodicalIF":0.0,"publicationDate":"2025-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Ultrasound-guided manual reduction combined with external fixation of small splints for the treatment of O'Brien type Ⅱ and Ⅲ radial neck fractures in children].","authors":"Quan-Wei Ding, Jun Ying, Ying Zhao","doi":"10.12200/j.issn.1003-0034.20250517","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20250517","url":null,"abstract":"<p><strong>Objective: </strong>To explore clinical efficacy of ultrasound-guided manual reduction combined with external fixation with small splints of fir bark in treating O'Brien typeⅡand Ⅲ radial neck fractures in children.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on clinical data of 21 children with type O'BrienⅡand Ⅲ radial neck fractures admitted from June 2023 to December 2024, including 11 boys and 10 girls; aged from 4 to 12 years old with an average of (8.43±1.60) years old;12 patients with O'Brien typeⅡand 9 patients with type Ⅲ. All treatments were carried out using ultrasound-guided manual reduction. Ultrasound examination was conducted again to check the quality of fracture reduction after reduction was completed. After the treatment, external fixation with small splints of fir bark was performed. The success rate of manual reduction and the incidence of complications during the process of manual reduction were observed. Postoperative images and post-operative functions were evaluated using Metaizeau standard.</p><p><strong>Results: </strong>All the children were followed up, and the duration ranged from 3 to 12 months. Closed reduction was successful in 19 children, while 2 children had difficulty in reduction and were transferred to surgical treatment. No related complications such as neurovascular injury occurred. Closed reduction was successful in 19 patients. Postoperative X-ray films showed good alignment and alignment of fractures, and the fracture healing time ranged from 4 to 7 weeks. Metaizeau criteria at 3 months after treatment, 17 patients were excellent and 2 good. In the later functional evaluation, all 19 patients were rated as excellent, and no obvious elbow joint dysfunction or residual pain occurred.</p><p><strong>Conclusion: </strong>Ultrasound-guided manual reduction could effectively increase success rate of manual reduction for O'Brien typeⅡand Ⅲ radial neck fractures in children, and reduce radiation and adverse outcomes.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"38 12","pages":"1255-9"},"PeriodicalIF":0.0,"publicationDate":"2025-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Observation on the clinical efficacy of <i>Huazhuo Sanjie Chubi</i> decoction() in the treatment of low-grade inflammation in chronic gouty arthritis].","authors":"Si-Yuan Lin, Xiao-Hua Chen, Zhuo-Ming Zheng, Fan Yang, Zhu-Mou Zhang, Jun Liu, Jia-Li Luo, Yan Xiao, Jie-Mei Guo, You-Xin Su","doi":"10.12200/j.issn.1003-0034.20250884","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20250884","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To explore clinical efficacy of &lt;i&gt;Huazhuo Sanjie Chubi&lt;/i&gt; decoction() in treating low-grade inflammation in chronic gouty arthritis (CGA).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;From May to December 2024, 68 male patients with CGA were admitted and divided into traditional Chinese medicine group and Western medicine group (1 patient dropped out and 4 patients excluded). There were 31 patients in traditional Chinese medicine group, aged from 21 to 63 years old with an average of (42.35±11.93) years old, body mass index (BMI) ranged from 21.0 to 37.5 kg·m&lt;sup&gt;-2&lt;/sup&gt; with an average of (26.87±3.58) kg·m&lt;sup&gt;-2&lt;/sup&gt;, and courses of disease raged from 3 to 30 years with an average of (9.55±6.25) years;treated with orally administered &lt;i&gt;Huazhuo Sanjie Chubi&lt;/i&gt; decoction(). There were 32 patients in Western medicine group, aged from 21 to 65 years old with an average of (37.47±10.79) years old, BMI ranged from 19.5 to 30.7 kg·m&lt;sup&gt;-2&lt;/sup&gt; with an average of (25.30±2.87) kg·m&lt;sup&gt;-2&lt;/sup&gt;, and courses of disease ranged from 4 to 21 years with an average of (8.50±4.15) years;treated with oral allopurinol. TCM syndrome score, Likert score for joint swelling and pain, visual analogue scale (VAS) for pain, serum uric acid and serum low-grade inflammation-related indicators of patients before and after treatment, including tumornecrosis factor-α (tumornecrosis factor-α) TNF-α, interleukin-1β (IL-1β), interleukin-6(IL-6), chemokine 2 (c-c motif chemokine ligand 2), changes of CCL2) and S100 calcium binding protein A8/A9(S100 calcium binding protein A8/A9, S100A8/A9) were observed and compared. Spearman correlation analysis was used to analyze correlations between SUA and IL-1β, IL-6, TNF-α, CCL2, and S100A8/A9.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Sixty-three patients were followed up for two months, and no adverse reactions occurred in any of them. After 2 months of treatment, the scores of TCM syndrome, Likert score of joint swelling and pain, and VAS in traditional Chinese medicine group were 9.00(8.00, 11.00), 2.00 (1.00, 3.00), and 0.00 (0.00, 1.00) points respectively;which were lower than 16.00 (15.00, 18.00), 4.00 (4.00, 5.00), and 2.00 (1.00, 2.00) in Western medicine group, and the differences were statistically significant(&lt;i&gt;P&lt;/i&gt;&lt;0.05). The serum uric acid level in Western medicine group was 465.68 (429.02, 500.94) μmol·L&lt;sup&gt;-1&lt;/sup&gt;, which was lower than that in traditional Chinese medicine group 496.03 (484.90, 522.73) μmol·L&lt;sup&gt;-1&lt;/sup&gt;, and the difference was statistically significant(&lt;i&gt;P&lt;/i&gt;&lt;0.05). The levels of serum IL-1β, IL-6, TNF-α, CCL2 and S100A8/A9 in traditional Chinese medicine group were (25.01±8.18) pg·ml-1, (16.97±5.01) ng·L&lt;sup&gt;-1&lt;/sup&gt;, (229.08±45.10) ng·L&lt;sup&gt;-1&lt;/sup&gt; and (503.50±72.16) pg·ml&lt;sup&gt;-1&lt;/sup&gt;, (13.35±2.80) pg·ml&lt;sup&gt;-1&lt;/sup&gt;, respectively;which were lower than those of Western medicine group (35.51±6.35) pg·ml-1, (21.13±2.49) ng·L&lt;sup&gt;-1&lt;/sup&gt;, (250.14±34.23) ng·L&lt;sup&gt;-1&lt;/sup&gt;, (567.","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"38 12","pages":"1201-9"},"PeriodicalIF":0.0,"publicationDate":"2025-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Current status and prospects of traditional Chinese medicine in prevention and treatment of gouty arthritis].","authors":"Xiao-Xu Li, Wei Cao, Guang-Cheng Wei, Jin-Jie Shi","doi":"10.12200/j.issn.1003-0034.20251160","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20251160","url":null,"abstract":"","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"38 12","pages":"1189-93"},"PeriodicalIF":0.0,"publicationDate":"2025-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical efficacy of TightRope combined with threaded anchors in the treatment of acromioclavicular joint dislocation].","authors":"Yi-Ke Qin, Jian-Ying Qin, Yi-Ming Luo","doi":"10.12200/j.issn.1003-0034.20250008","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20250008","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To compare short-term and long-term efficacy of TightRope combined with threaded anchor bolts and clavicular hook plate fixation in treating acromioclavicular joint dislocation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A retrospective analysis was conducted on clinical data of 90 patients with acromioclavicular joint dislocation admitted from March 2020 to March 2024. They were divided into anchor group and plate group according to surgical methods. There were 48 patients in anchor group, including 30 males and 18 females, aged from 18 to 65 years old with an average of (42.35±9.21) years old;20 patients caused by traffic accident injuries, 18 patients caused by sports injuries and 10 patients caused by falling;15 patients with type Ⅲ, 20 patients with type Ⅳ, and 13 patients with type Ⅴ according to Rockwood classification;26 patients on the left side and 22 patients on the right side;the time from injury to operation ranged from 2 to 7 days with an average of (4.62±1.13) days;TightRope combined with wire anchor technology was adopted. There were 42 patients in steel plate group, including 22 males and 20 females, aged from 20 to 64 years old with an average of (41.87±8.97) years old;18 patients caused by traffic accident injuries, 15 patients caused by sports injuries and 9 patients caused by falling; 14 patients with type Ⅲ, 17 patients with type Ⅳ, and 11 patients with type Ⅴ according to Rockwood classification;22 patients on the left side and 20 patients on the right side;the time from injury to operation ranged from 3 to 7 days with an average of (4.54±1.10) days;clavicular hook plates were used for fixation. The operation time, intraoperative blood loss, hospital stay and complications between two groups were compared. The changes of shoulder joint range of motion (flexion and elevation, abduction and elevation), visual analogue scale (VAS) for pain and Constant-Murley score were compared before operation, 3 months after operation respectively. At the latest follow-up, Karlsson score was used to compare its clinical efficacy.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Both groups of patients were successfully completed surgery and were followed up. The follow-up time of anchor group ranged from 8 to 33 months with an average of (16.22±5.09) months, and that of plate group ranged from 9 to 37 months with an average of (16.72±6.23) months. There was no statistically significant difference between two groups (&lt;i&gt;P&lt;/i&gt;&gt;0.05). There was no statistically significant difference in operation time between two groups (&lt;i&gt;P&lt;/i&gt;&gt;0.05). The intraoperative blood loss and postoperative hospital stay in anchor group were (50.26±14.82) ml and (5.21±1.29) d respectively, which were better than those in plate group (68.90±16.18) ml and (6.28±1.52) d, and the differences were statistically significant(&lt;i&gt;P&lt;/i&gt;&lt;0.001). At 3 months after operation, the range of motion of forward flexion, upward lift and abduction and upward lift in anchor group were","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"38 12","pages":"1224-30"},"PeriodicalIF":0.0,"publicationDate":"2025-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Effect of formononetin on endoplasmic reticulum stress and neuronal apoptosis in rats with chronic compressive cervical spinal cord injury].","authors":"Ya-Yun Zhang, Min Yao, Rui-Rui Xue, Xing Ding, Jin-Hai Xu, Xue-Jun Cui, Wen Mo","doi":"10.12200/j.issn.1003-0034.20240199","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20240199","url":null,"abstract":"<p><strong>Objective: </strong>To explore effect and mechanism of formononetin on recovery of neurological function after chronic spinal cord injury (SCI) in rats.</p><p><strong>Methods: </strong>Twenty-four SPF male SD rats, aged from 8 to 9 weeks old, weighted (327.29±15.19) g, were selected and randomly divided into sham operation group(Sham group), model group (Vehicle group), and formononetin group, with 8 rats in each group. Vehicle group and formononetin group were established chronic SCI models in rats by hydrogel compression. On the first day after modeling in formononetin group, formononetin officinalis solution was continuous administered orally (with a standard of 30 mg·kg^-1) for 28 days, once a day. Basso-Beattie-Bresnahan (BBB) score, forelimb grip strength and rotating bar test of rats were performed in each group at 1, 7, 14, 21 and 28 days after modeling respectively to evaluate the limb motor function. Twenty-eight days after modeling, cardiac perfusion samples were collected to detect endoplasmic reticulum stress and neuronal apoptosis in spinal cord tissue. Hematoxylin-eosin staining was used to observe SCI, Nissl staining was used to observe number of surviving neurons, and Western blot (WB) was used to detect Bcl-2-associated X protein(Bax), B-cell lymphoma-2(Bcl-2) proteins and apoptosis-related proteins. The expression of endoplasmic reticulum stress pathway-related proteins was observed by immunofluorescence staining.</p><p><strong>Results: </strong>Formononetin group were better than Vehicle group in BBB score on the 21st day after operation and grip test on the 3rd, 7th and 21st days, there were statistically differences(<i>P</i><0.05). The results of HE and Nissl staining showed the number of surviving nerve cells in formononetin group were better than those in Vehicle group, and the difference were statistically significant(<i>P</i><0.05). WB results showed the expression of Bcl-2 was upregulated, and protein expressions of Bax, C/EBP homologous protein(CHOP), phosphorylated protein kinase R-like endoplasmic reticulum kinase(p-PERK), and phosphorylated eukaryotic initiation factor 2α(p-eIF2α) in formononetin group were down regulated compared with Vehicle group, the differences were statistically significant(<i>P</i><0.05). Immunofluorescence showed the protein expressions of p-PERK and activating transcription factor 6(ATF6) in neurons in formononetin group decreased compared with Vehicle group, and the differences were statistically significant (<i>P</i><0.05).</p><p><strong>Conclusion: </strong>Formononetin could alleviate pathological changes after chronic SCI in rats, improve behavioral scores, and promote the recovery of spinal cord nerve function. The specific mechanism may be related to the inhibition of necrotic apoptosis mediated by endoplasmic reticulum stress signaling pathway.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"38 12","pages":"1241-8"},"PeriodicalIF":0.0,"publicationDate":"2025-12-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}