Zhongguo gu shang = China journal of orthopaedics and traumatology最新文献

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[Clinical observation on the efficacy of iliac bone grafting under wrist arthroscopy for stageⅡavascular necrosis of the lunate]. [腕关节镜下髂骨移植术治疗Ⅱ期月骨缺血性坏死的临床观察]。
Zhongguo gu shang = China journal of orthopaedics and traumatology Pub Date : 2026-04-25 DOI: 10.12200/j.issn.1003-0034.20240780
Wang Xiang, Shun Yang, Hongji Gu
{"title":"[Clinical observation on the efficacy of iliac bone grafting under wrist arthroscopy for stageⅡavascular necrosis of the lunate].","authors":"Wang Xiang, Shun Yang, Hongji Gu","doi":"10.12200/j.issn.1003-0034.20240780","DOIUrl":"10.12200/j.issn.1003-0034.20240780","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the clinical efficacy of iliac bone grafting under wrist arthroscopy and its effect on wrist function in the treatment of stageⅡavascular necrosis of the lunate.</p><p><strong>Methods: </strong>Between January 2020 and January 2023, 80 patients with stageⅡavascular necrosis of the lunate were enrolled. Forty patients were treated with wrist neutral position brace fixation (brace group), including 17 males and 23 females, aged from 31 to 55 years with a mean of(41.38±5.52)years. The remaining 40 patients were treated with iliac bone grafting under wrist arthroscopy (bone graft group), including 15 males and 25 females, aged from 29 to 52 years with a mean of(42.00±5.13) years. All patients in both groups underwent preoperative CT and other imaging examinations to confirm the status of lunate necrosis. The wrist function was evaluated using the Mayo wrist score, and pain severity was assessed using the visual analog scale (VAS) preoperatively and at 1, 3, 6, and 12 months postoperatively. Grip strength, wrist height ratio, radioscaphoid angle, and wrist range of motion were measured and compared preoperatively and at 12 months postoperatively. At 12 months postoperatively, clinical efficacy was evaluated using the Cooney scoring system, and complications in both groups were recorded.</p><p><strong>Results: </strong>All patients were followed up for 1 year. Compared with preoperative values, the total Mayo scores in both groups increased gradually at 1, 3, 6, and 12 months postoperatively, with statistically significant differences (all <i>P</i><0.001). There were no significant differences in Mayo wrist scores between the brace group and the bone graft group preoperatively and at 1 month postoperatively (<i>P</i>>0.05). At 3, 6, and 12 months postoperatively, the total Mayo scores in the bone graft group (66.93±1.87), (79.00±2.47), (90.00±2.60) were higher than those in the brace group(63.98±2.25), (71.98±2.17), (80.53±1.72), there were statistically significant differences(all <i>P</i><0.001). Compared with preoperative and 1 month postoperative values, the VAS scores decreased gradually at 3, 6, and 12 months postoperatively, with statistically significant differences (all <i>P</i><0.001). There was no significant difference in preoperative VAS scores between the brace group and the bone graft group (<i>P</i>>0.05). At 1, 3, 6, and 12 months postoperatively, the VAS in the bone graft group (4.59±0.82), (2.80±0.64), (1.66±0.69), (0.98±0.57) were lower than those in the brace group (5.23±0.97), (4.05±0.90), (2.05±0.75), (1.58±0.59), with statistically significant differences (all <i>P</i><0.05). At 12 months postoperatively, the grip strength in both groups was higher than the preoperative level, while the wrist height ratio and radioscaphoid angle were lower than the preoperative levels. The grip strength and wrist height ratio in the bone graft group (23.10±3.63) kg, (0.52±0.09) were better than those","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 4","pages":"372-9"},"PeriodicalIF":0.0,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Study on LncRNA H19 promoting osteogenic differentiation of umbilical cord mesenchymal stem cells]. [LncRNA H19促进脐带间充质干细胞成骨分化的研究]。
Zhongguo gu shang = China journal of orthopaedics and traumatology Pub Date : 2026-04-25 DOI: 10.12200/j.issn.1003-0034.20230703
Yunpeng Guo, Yan Xie, Bingyi Wei, Taoli Ning, Na Wang
{"title":"[Study on LncRNA H19 promoting osteogenic differentiation of umbilical cord mesenchymal stem cells].","authors":"Yunpeng Guo, Yan Xie, Bingyi Wei, Taoli Ning, Na Wang","doi":"10.12200/j.issn.1003-0034.20230703","DOIUrl":"10.12200/j.issn.1003-0034.20230703","url":null,"abstract":"<p><strong>Objective: </strong>To observe the effects of long non-coding RNA H19(lncRNA H19) transfection on the expression of multiple osteogenic and angiogenic factors and the osteogenic capacity in human umbilical cord mesenchymal stem cells (hUC-MSCs), so as to provide a preliminary research basis for the future development of bone defect fillers with favorable blood supply.</p><p><strong>Methods: </strong>Bioinformatics analysis was performed to confirm that H19 could regulate bone formation-related microRNAs (miRNAs) and their downstream osteogenic and angiogenic factors. The target molecules were finally identified as miR-137-3p, miR-383-5p, and their regulated factors including integrin-binding sialoprotein (IBSP), Runt-related transcription factor 2 (RUNX2), and fibroblast growth factor 5 (FGF5). Human umbilical cord mesenchymal stem cells were cultured in vitro. lncRNA H19 was then transfected into hUC-MSCs. Reverse transcription-polymerase chain reaction(RT-PCR) was used to detect the expression abundance of miR-137-3p and miR-383-5p in transfected cells. Western blot was applied to measure the expression levels of IBSP, Runx2 and FGF5. Alkaline phosphatase (ALP) staining and alizarin red S staining were conducted to evaluate the osteogenic capacity of cells after H19 transfection. We verified whether lncRNA H19 transfection could downregulate the expression of miR-137-3p and miR-383-5p, thereby upregulating the expression of osteogenic and angiogenic factors IBSP, Runx2 and FGF5, and confirmed that lncRNA H19 transfection promoted osteogenic differentiation of hUC-MSCs.</p><p><strong>Results: </strong>The expression levels of miR-137-3p and miR-383-5p were downregulated in hUC-MSCs transfected with lncRNA H19, whereas the expression levels of Runx2, IBSP and FGF5 were significantly increased from (0.533±0.058), (0.633±0.058), (0.500±0.100) before transfection to (1.300±1.100), (1.233±0.058), (0.967±0.115) after transfection, respectively, with statistically significant differences (<i>P</i>=0.000, <i>P</i>=0.000, <i>P</i>=0.006). Moreover, hUC-MSCs exhibited enhanced osteogenic capacity after H19 transfection.</p><p><strong>Conclusion: </strong>Transfection with lncRNA H19 promotes the expression of several osteogenic and angiogenic factors and enhances the osteogenic capacity of hUC-MSCs. This provides a potential basis for the future development of tissue-engineered bone incorporating lncRNA H19 to improve its osteogenic and angiogenic performance.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 4","pages":"401-6"},"PeriodicalIF":0.0,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Improving effects of balanced reduction manipulation for cervical physiological curvature and inflammatory response in patients with vertebroarterial cervical spondylosis]. [提高平衡复位手法对椎动脉型颈椎病患者颈椎生理曲度及炎症反应的影响]。
Zhongguo gu shang = China journal of orthopaedics and traumatology Pub Date : 2026-04-25 DOI: 10.12200/j.issn.1003-0034.20241124
Fengcun Hu, Wenlin Lin, Zuyao Du, Yibing Li
{"title":"[Improving effects of balanced reduction manipulation for cervical physiological curvature and inflammatory response in patients with vertebroarterial cervical spondylosis].","authors":"Fengcun Hu, Wenlin Lin, Zuyao Du, Yibing Li","doi":"10.12200/j.issn.1003-0034.20241124","DOIUrl":"10.12200/j.issn.1003-0034.20241124","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To investigate the improving effect of balanced reduction manipulation on cervical physiological curvature and inflammatory response in patients with vertebroarterial cervical spondylosis, so as to provide a reference for clinical treatment planning.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Between June 2021 and November 2023, a total of 160 patients with vertebral artery-type cervical spondylosis were enrolled and divided into two groups based on treatment modalities:a medication with bone-setting manipulation group and a medication with balance repositioning group. The medication with bone-setting manipulation group included 80 patients (48 males and 32 females), aged from 18 to 64 years with a mean age of(44.87±5.47) years and disease duration ranging from 1 to 24 months with a mean of(10.45±3.11) months. These patients received conventional western medicine therapy along with bone-setting manipulation techniques. The medication with balance repositioning group consisted of 80 patients(47 males and 33 females), aged 18 to 64 years old with a mean age of (44.91±5.44) years old, the disease duration ranged from 1 to 24 monthsn with a mean duration of (10.49±3.08) months. This group was treated with conventional western medicine combined with balance repositioning bone-setting manipulation. Comparative analyses were performed between the two groups regarding primary symptoms including neck and shoulder pain scores, cervical tenderness, limited cervical mobility, upper limb numbness and pain, vertigo severity scores, peak systolic velocity(VP), end-diastolic velocity(VD), cervical physiological curvature (cervical arc-chord distance), neck disability index (NDI), interleukin-4 (IL-4), interleukin-8 (IL-8), tumor necrosis factor-alpha (TNF-α), clinical efficacy outcomes, and adverse reactions.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The scores for neck and shoulder pain, cervical tenderness, limited cervical mobility, and upper limb numbness pain decreased significantly in both groups after treatment (&lt;i&gt;P&lt;/i&gt;&lt;0.05).Post-treatment scores for neck and shoulder pain, cervical tenderness, limited cervical mobility, and upper limb numbness pain in the medication with balance repositioning group were(1.13±0.22), (1.78±0.25), (1.68±0.27), and (0.64±0.14), respectively. The medication with bone-setting manipulation group were (1.95±0.37), (2.36±0.32), (1.91±0.35), and (0.92±0.21), respectively. The difference was statistically significant(&lt;i&gt;P&lt;/i&gt;&lt;0.05). Vertigo severity scores improved significantly in both groups after treatment (&lt;i&gt;P&lt;/i&gt;&lt;0.05). Notably, the post-treatment score in the medication with Balance repositioning group(13.52±2.04) was significantly higher than that in the medication with bone-setting manipulation group(12.04±1.93), there was statistically significant difference(&lt;i&gt;P&lt;/i&gt;&lt;0.05). Both VP and VD increased significantly in both groups (&lt;i&gt;P&lt;/i&gt;&lt;0.05). Specifically, the VP and VD values for the vertebral and basilar ar","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 4","pages":"380-7"},"PeriodicalIF":0.0,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Clinical controlled study of Zhongyi Ointment() in the treatment of Kellgren-Lawrence gradeⅡknee osteoarthritis with moderate-to-severe pain]. 【中益软膏()治疗kelgren - lawrence级Ⅱ膝关节骨性关节炎伴中重度疼痛的临床对照研究】。
Zhongguo gu shang = China journal of orthopaedics and traumatology Pub Date : 2026-04-25 DOI: 10.12200/j.issn.1003-0034.20250486
Kexiao Yu, Chuanhong Li, Zhen He, Yuanhang He, Yang Jin, Yu Zou, Weizhong Lu, Jinwei Ran
{"title":"[Clinical controlled study of Zhongyi Ointment() in the treatment of Kellgren-Lawrence gradeⅡknee osteoarthritis with moderate-to-severe pain].","authors":"Kexiao Yu, Chuanhong Li, Zhen He, Yuanhang He, Yang Jin, Yu Zou, Weizhong Lu, Jinwei Ran","doi":"10.12200/j.issn.1003-0034.20250486","DOIUrl":"10.12200/j.issn.1003-0034.20250486","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the clinical efficacy and safety of <i>Zhongyi</i> Ointment() in the treatment of Kellgren-Lawrence grade (K-L)Ⅱknee osteoarthritis with moderate-to-severe pain.</p><p><strong>Methods: </strong>This study adopted a prospective, randomized, double-blind, placebo-controlled design. Patients were recruited from November 2022 to October 2023. A total of 80 participants meeting the diagnostic criteria for K-L gradeⅡknee osteoarthritis at the acute exacerbation stage were enrolled and randomly assigned to the <i>Zhongyi</i> Ointment() group or the placebo group, with a uniform treatment course of 6 days. Two patients were lost to follow-up in the <i>Zhongyi</i> Ointment() group and three in the placebo group, resulting in a final sample of 75 patients included in the statistical analysis. The <i>Zhongyi</i> Ointment() group comprised 38 patients (15 males, 23 females) aged from 55 to 80 years (70.97±5.05)years. The placebo group included 37 patients (12 males, 25 females) aged from 52 to 79 years (68.70±6.11)years. The primary outcome measures were the Western Ontario and McMaster Universities osteoarthritis index (WOMAC) scores, knee joint range of motion, and the occurrence of adverse events before and after treatment.</p><p><strong>Results: </strong>On day 6 of treatment, the total WOMAC score in the <i>Zhongyi</i> Ointment() group decreased from (109.79±11.32) scores at baseline to( 44.92±14.84) scores (<i>P</i><0.001), which was significantly lower than (56.78±9.33) scores in the placebo group (<i>P</i><0.001). Improvements in all WOMAC subscales (pain, stiffness, physical function) in the <i>Zhongyi</i> Ointment() group were superior to those in the placebo group (all <i>P</i><0.05), with more rapid symptom relief in the first 3 days. The knee joint range of motion in the <i>Zhongyi</i> Ointment() group was (127.21±15.87)° which was significantly higher than (117.11±13.44)° in the placebo group (<i>P</i>=0.028). No serious adverse events occurred in either group.</p><p><strong>Conclusion: </strong><i>Zhongyi</i> Ointment() can rapidly and significantly improve symptoms in patients with K-L gradeⅡknee osteoarthritis with moderate-to-severe pain during the acute exacerbation stage, with definite short-term efficacy and favorable safety. Continuous treatment helps to consolidate the therapeutic effect and warrants further validation through multicenter studies with large sample sizes, as well as investigations into the underlying mechanisms.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 4","pages":"336-42"},"PeriodicalIF":0.0,"publicationDate":"2026-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147843584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Advances on the treatment of the first-time patellar dislocation in children and adolescents]. [儿童青少年首次髌骨脱位的治疗进展]。
Zhongguo gu shang = China journal of orthopaedics and traumatology Pub Date : 2026-03-25 DOI: 10.12200/j.issn.1003-0034.20241242
Jiale Yang, Feng Liu, Lin Gao, Tanglian Li, Chao Li
{"title":"[Advances on the treatment of the first-time patellar dislocation in children and adolescents].","authors":"Jiale Yang, Feng Liu, Lin Gao, Tanglian Li, Chao Li","doi":"10.12200/j.issn.1003-0034.20241242","DOIUrl":"10.12200/j.issn.1003-0034.20241242","url":null,"abstract":"<p><p>The first patellar dislocation in children and adolescents is a common clinical sports injury. The controversy in the treatment strategies poses a significant challenge to long-term functional prognosis of patients. Studies have shown that demographic factors (young age, female gender), skeletal maturity, and anatomical abnormalities (such as trochlear dysplasia (TD), increased distance between tibial tubercle and trochlear groove (TT-TG) were closely related to patellar dislocation. Although conservative treatment is the preferred option, it has a high recurrence rate and is prone to leaving knee joint dysfunction; surgical treatment, such as medial patella femoral ligament reconstruction (MPFLR) and trochlear reshaping, has gradually become an important choice for patients with moderate to high risks (those with bone and cartilage fractures, Dejour-B-D type trochlear dysplasia, or those who fail conservative treatment). Currently, research focuses on optimizing individualized surgical plans based on anatomical risk stratification, improving bone and cartilage protection techniques, and evaluating efficacy of combined treatment modalities. The author believes that the treatment of the first patellar dislocation should take into account anatomical features, skeletal maturity, and functional requirements, and prioritize conservative treatment combined with early rehabilitation;however, for high-risk patients (such as TT-TG > 20 mm, severe trochlear dysplasia), individualized surgical intervention should be actively implemented to reduce recurrence rates and improve prognosis.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 3","pages":"318-24"},"PeriodicalIF":0.0,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Comparison of clinical efficacy between total visual endoscopic lumbar fusion and traditional posterior fusion in the treatment of single-segment lumbar spinal stenosis]. 【全视内镜腰椎融合术与传统后路融合术治疗单节段腰椎管狭窄症的临床疗效比较】。
Zhongguo gu shang = China journal of orthopaedics and traumatology Pub Date : 2026-03-25 DOI: 10.12200/j.issn.1003-0034.20221201
Rongxin Sun, Daoyu Huang, Yunlong Wu, Luji Xu, Zhongqiang Yang, Qilou Liang, Tao Cheng, Shengyou Zhang
{"title":"[Comparison of clinical efficacy between total visual endoscopic lumbar fusion and traditional posterior fusion in the treatment of single-segment lumbar spinal stenosis].","authors":"Rongxin Sun, Daoyu Huang, Yunlong Wu, Luji Xu, Zhongqiang Yang, Qilou Liang, Tao Cheng, Shengyou Zhang","doi":"10.12200/j.issn.1003-0034.20221201","DOIUrl":"10.12200/j.issn.1003-0034.20221201","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To compare clinical efficacy of endoscopic lumbar interbody fusion (Endo-PLIF) and traditional posterior lumbar interbody fusion (PLIF) in treating single-segment lumbar spinal stenosis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;From July 2021 to April 2022, 56 patients with lumbar spinal stenosis who underwent lumbar decompression and fusion were included, and divided into observation group and control group according to treatment methods. There were 29 patients in observation group, including 16 males and 13 females;aged from 41 to 65 years old with an average of(53.64±6.34) years;body mass index (BMI) ranged from 10 to 35 kg·m&lt;sup&gt;-2&lt;/sup&gt; with an average of (23.38±2.92) kg·m&lt;sup&gt;-2&lt;/sup&gt;;2 patients with L&lt;sub&gt;3,4&lt;/sub&gt;, 15 patients with L&lt;sub&gt;4,5&lt;/sub&gt;, and 12 patients with L&lt;sub&gt;5&lt;/sub&gt;S&lt;sub&gt;1&lt;/sub&gt;;treated with Endo-PLIF. There were 27 patients in control group, including 15 males and 12 females;aged from 42 to 60 years old with an average of (55.41±5.82) years;BMI ranged from 12 to 28 kg·m&lt;sup&gt;-2&lt;/sup&gt; with an average of (24.20±2.18) kg·m&lt;sup&gt;-2&lt;/sup&gt;;1 patient with L&lt;sub&gt;3,4&lt;/sub&gt;, 17 patients with L&lt;sub&gt;4,5&lt;/sub&gt;, and 9 patients with L&lt;sub&gt;5&lt;/sub&gt;S&lt;sub&gt;1&lt;/sub&gt;;treated with PLIF. Operation time, incision length, intraoperative blood loss, postoperative drainage volume, hospital stay, and occurrence of postoperative complications between two groups were compared. Visual analogue scale (VAS) for lower back and lower limb pain and Oswestry Disability index (ODI) at preoperative, 3 days postoperative, 3 months postoperative, and the latest follow-up postoperative were assessed.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Both groups of patients were followed up, the follow-up period for observation group ranged from 4 to 8 months with an average of (7.3±2.2) months, and for control group ranged from 6 to 10 months with an average of (8.1±1.7) months;there was no statistically significant difference between two groups (&lt;i&gt;P&lt;/i&gt;&gt;0.05). Operation time, incision length, intraoperative blood loss, postoperative drainage volume and hospital stay of observation group were (140.24±45.39) min, (3.10±0.70) cm, (125.36±25.59) mL, (50.36±15.59) mL and (11.00±2.36) days respectively, while those of control group were (132.56±48.26) min, (10.10±1.00) cm, (258.51±38.25) mL, (155.28±21.34) mL and (18.00±2.58) days respectively;and the differences were statistically significant compared between two groups (&lt;i&gt;P&lt;/i&gt;&lt;0.05). VAS and ODI scores of lumbar and leg regions at 3 days, 3 months, and the final follow-up after operation were all improved compared with those of preoperative, and the differences were statistically significant (&lt;i&gt;P&lt;/i&gt;&lt;0.05). Moreover, VAS and ODI scores of lumbar and leg regions at each time point after operation in observation group were better than those in control group (&lt;i&gt;P&lt;/i&gt;&lt;0.05). At the latest follow-up, there were no cases of screw fracture, loosening, or fusion device withdrawal were found. No nerve root injuries occ","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 3","pages":"263-9"},"PeriodicalIF":0.0,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Correlation between sarcopenia and osteoporosis]. [肌肉减少症与骨质疏松症的相关性]。
Zhongguo gu shang = China journal of orthopaedics and traumatology Pub Date : 2026-03-25 DOI: 10.12200/j.issn.1003-0034.20240972
Junhao Li, Jinyu Li
{"title":"[Correlation between sarcopenia and osteoporosis].","authors":"Junhao Li, Jinyu Li","doi":"10.12200/j.issn.1003-0034.20240972","DOIUrl":"10.12200/j.issn.1003-0034.20240972","url":null,"abstract":"<p><p>Sarcopenia and osteoporosis are two common metabolic diseases among the elderly population. Studies have found that there was a mutually reinforcing correlation in the process of their onset. Epidemiological research indicated that the incidence rates of sarcopenia and osteoporosis were positively correlated. Genetic studies have discovered genes that could simultaneously control low bone density and low muscle mass. Cell biology research has found that there were cytokines that act on both muscle cells and bone cells, and changes in their content could directly cause a decrease in muscle mass and bone density. Risk factor studies have found that there were common risk factors with a relatively clear mechanism that could cause the simultaneous onset of sarcopenia and osteoporosis. However, comprehensive high-level evidence demonstrating the mutual promotion of sarcopenia and osteoporosis during their onset was not yet complete, and the research on mechanism of their co-occurrence was not yet perfect, which has hindered the development of drugs for treating these diseases. Therefore, timely diagnosis of one of these diseases and control of common risk factors are effective methods for preventing and treating the co-occurrence of sarcopenia and osteoporosis.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 3","pages":"314-8"},"PeriodicalIF":0.0,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Imaging study on tibial torsion malreduction after tibial intramedullary nailing]. [胫骨髓内钉治疗后胫骨扭转复位不良的影像学研究]。
Zhongguo gu shang = China journal of orthopaedics and traumatology Pub Date : 2026-03-25 DOI: 10.12200/j.issn.1003-0034.20240138
Chengwei Chen, Feng Wang
{"title":"[Imaging study on tibial torsion malreduction after tibial intramedullary nailing].","authors":"Chengwei Chen, Feng Wang","doi":"10.12200/j.issn.1003-0034.20240138","DOIUrl":"10.12200/j.issn.1003-0034.20240138","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To explore changes in physiological torsion angle of tibia and torsion angle of tibia after intramedullary nailing for tibial shaft fractures, and to determine whether torsion angle of the uninjured side of tibia could be used as a reference standard for judging the recovery of torsion angle of the injured side after operation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A retrospective analysis was conducted on clinical data of 154 patients with unilateral tibial shaft fractures who underwent closed reduction with intramedullary nails from January 2018 to December 2023. There were 110 males and 44 females;aged from 22 to 90 years old with an average of (41.0±18.6) years old;82 patients on the right side and 72 patients on the left side;95 patients with type A, 35 patients with type B, and 24 patients with type C according to AO fracture classification;6 patients with proximal tibial fractures, 47 patients with middle tibial fractures, 91 patients with distal tibial fractures, and 10 patients with segmental fractures;127 patients associated fibular fractures, including 30 patients with proximal fibular fractures, 43 patients with middle fibular fractures, 38 patients with distal fibular fractures, and 16 patients with segmental fibular fractures. Postoperative CT was used to assess bilateral tibial torsion angles. The incidence, grading and distribution of poor tibial torsion angle reduction were statistically analyzed. The differences in physiological tibial torsion angles of healthy limbs on the left and right sides were also examined. The distribution of poor reduction of left or right tibial torsion angles after correction of baseline differences was analyzed, the classification of tibial torsion angles after baseline correction was summarized, and the related factors of poor torsion angle reduction were investigated.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Among 55 patients (36%), there was a 10° or greater change in tibial torsion angle after operation;there was a difference of approximately 10° in torsion angle between the left and right tibial intramedullary nails after operation, which was statistically significant (&lt;i&gt;P&lt;/i&gt;=0.000). After operation, the right tibial shaft fracture was more likely to result in abnormal external rotation, while the left tibial shaft fracture was more prone to abnormal internal rotation. There was a statistically significant difference in distribution of abnormal torsional angle reduction between left and right sides (&lt;i&gt;P&lt;/i&gt;=0.000). The normal tibia had a tibial torsion and external rotation angle. The right side (41.1±8.0)° has an additional 4° of external rotation compared to the left side (37.0±8.2)° (&lt;i&gt;P&lt;/i&gt;&lt;0.01). After the 4° correction, the incidence of poor reduction of torsion angle decreased (45 patients, 29%), and the distribution of poor reduction of torsion angles on the left and right sides became more balanced (&lt;i&gt;P&lt;/i&gt;=0.588), and there was no statistically significant differen","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 3","pages":"239-45"},"PeriodicalIF":0.0,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Application of palmar incision and levering technique in the surgical treatment of distal radius fractures in elderly]. 掌部切开加杠杆技术在老年桡骨远端骨折手术治疗中的应用
Zhongguo gu shang = China journal of orthopaedics and traumatology Pub Date : 2026-03-25 DOI: 10.12200/j.issn.1003-0034.20250096
Jintao Hu, Jun Yao, Zhimin Miao, Liqi Ruan
{"title":"[Application of palmar incision and levering technique in the surgical treatment of distal radius fractures in elderly].","authors":"Jintao Hu, Jun Yao, Zhimin Miao, Liqi Ruan","doi":"10.12200/j.issn.1003-0034.20250096","DOIUrl":"10.12200/j.issn.1003-0034.20250096","url":null,"abstract":"<p><strong>Objective: </strong>To explore clinical efficacy of palmar incision and levering technique in the surgical treatment of distal radius fractures in the elderly.</p><p><strong>Methods: </strong>From October 2022 to December 2023, 28 patients with distal radius fractures who underwent surgical treatment were admitted. Among them, including 10 male and 18 female;the age was 68 (64, 72) years old; the disease duration was 3 (2, 7) days;bone density was -3.1 (-2.7, -3.3);11 patients on the left side and 17 patients on the right side;19 patients caused by injuries, and 9 patients caused by traffic accidents;according to AO classification, 20 patients with type A3 and 8 patients with type C2. Palmar inclination angle, ulnar deviation angle and radial height before treatment and the latest follow-up were observed and compared. The modified Mayo wrist score(MMWS) was used to evaluate the recovery of wrist joint function. The fracture healing and the occurrence of complications were also observed.</p><p><strong>Results: </strong>All patients were followed up for 11 (9, 13) months. None of patients experienced complications such as incision infection, re-loss of fracture reduction, or non-union of fractures. The palmar inclination angle, ulnar deviation angle, and radial height improved from (-2.7±1.5)°, (16.2±2.7)°, and (2.1±1.3) mm before treatment to (12.1±2.6)°, (20.6±2.1)°, and (10.5±1.2) mm at the latest follow-up, and the differences were statistically significant(<i>P</i><0.05);at the latest follow-up, MMWS score was (94.3±3.7) points, with 23 patients got excellent result and 5 good.</p><p><strong>Conclusion: </strong>Palmar window dislocation technique for treating patients with osteoporotic distal radius fractures could effectively restore palmar inclination angle of radius. Combined with the implantation of artificial bone, it could effectively maintain the fracture reduction and reduce risk of re-displacement.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 3","pages":"235-9"},"PeriodicalIF":0.0,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Construction and reflection of the core outcome set for clinical trials of Mongolian orthopedic manipulation therapy for humerus surgical neck fracture]. 【蒙古式骨科手法治疗肱骨外科颈骨折临床试验核心结局集的构建与反思】。
Zhongguo gu shang = China journal of orthopaedics and traumatology Pub Date : 2026-03-25 DOI: 10.12200/j.issn.1003-0034.20240842
Xueyin Chen, Aihua Jin, Lihong Yang, Zhirong Fan, Teri Gele, Xinfeng Guo, Shaonan Liu
{"title":"[Construction and reflection of the core outcome set for clinical trials of Mongolian orthopedic manipulation therapy for humerus surgical neck fracture].","authors":"Xueyin Chen, Aihua Jin, Lihong Yang, Zhirong Fan, Teri Gele, Xinfeng Guo, Shaonan Liu","doi":"10.12200/j.issn.1003-0034.20240842","DOIUrl":"10.12200/j.issn.1003-0034.20240842","url":null,"abstract":"<p><strong>Objective: </strong>To develop a set of scientific, standardized and Mongolian medical characteristic-based core outcome sets(COS) for the clinical trial of Mongolian osteopathic manipulation in the treatment of humerus surgical neck fractures (HSNF).</p><p><strong>Methods: </strong>This study constructed COS by combining literature research, questionnaire surveys, expert consultations and consensus conferences. Firstly, it retrieved the databases and analyzed the published research reports and clinical research protocols, conducted questionnaires for doctors and patients, extracted and collected the efficacy evaluation indicators of HSNF to form the outcome indicator pool. Then, it used Delphi survey method to invite Mongolian medicine, traditional Chinese medicine, and Western medicine orthopedic physicians as well as clinical research workers to rate the importance of the indicators. Finally, a consensus conference was held to determine the final COS.</p><p><strong>Results: </strong>Through literature search, 13, 333 pieces of information were obtained. After screening, 61 pieces of literature were finally included. A total of 21 doctors and patients participated in the questionnaire survey. The results of the research in the literature and the questionnaire survey indicators were sorted and extracted, forming an outcome indicator pool consisting of 31 indicators. After two rounds of Delphi surveys, experts rated the indicators, and 26 indicators were included in the consensus meeting for discussion. Finally, the consensus meeting determined that 11 outcome indicators entered the core outcome indicator set. Seven indicator domains were covered:pain (patients' self-reported pain, tenderness at the fracture site), functional status (joint range of motion of the affected limb, muscle strength of the affected limb, ability to independently complete daily activities), quality of life (quality of life assessment), imaging indicators (fracture healing time, excellent rate of fracture reduction), patient perspective (patient treatment satisfaction), safety indicators (total incidence rate of adverse reactions/events), and Mongolian medicine indicators (Mongolian medicine syndrome evaluation). Measurement methods or tools were recommended for some indicators.</p><p><strong>Conclusion: </strong>A clinical research COS integrating the characteristics of Mongolian medicine was established, providing a clear range of outcome indicators for the clinical research of Mongolian osteopathy in treating HSNF. This will offer more applicable evidence for Mongolian clinical decision-making and patient care. Future studies should further validate and promote the application of this COS to facilitate the wider recognition and application of Mongolian osteopathy in the modern medical system.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 3","pages":"288-96"},"PeriodicalIF":0.0,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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