{"title":"[A case report of left external iliac vein injury treated by great saphenous vein bypass surgery].","authors":"Chenhui Yang, Gonglin Zhang, Yujin He, Yayi Xia","doi":"10.12200/j.issn.1003-0034.20240084","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20240084","url":null,"abstract":"","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 9","pages":"943-5"},"PeriodicalIF":0.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Update of Pilon fracture classification].","authors":"Rongjiang Li, Han Tang, Quan Zhou, Zhijian Ma","doi":"10.12200/j.issn.1003-0034.20240357","DOIUrl":"10.12200/j.issn.1003-0034.20240357","url":null,"abstract":"<p><p>An ideal fracture classification system facilitates stratified diagnosis, standardized treatment, prognostic prediction, scientific research, peer communication, and health education. All of them were particularly important for the management of Pilon fractures. Currently, Pilon fracture classifications were commonly based on plain radiographs and CT scans. The former included the Rüedi-Allgöwer, Kellam-Waddell, Ovadia, AO/OTA, and Letts classifications, which were convenient for assessing general fracture morphology, evaluating alignment, and deducing injury mechanisms. However, they were limited in visualizing articular surface, planning surgical approaches and fixation strategies. The latter included Topliss, four-column, three-column, and Leonetti classifications, which offer advantages in evaluating articular surface fractures, and in guiding surgical approaches and internal fixation strategies, but lack description of the spatial configuration of fracture surfaces. At present, no existing classification system incorporated all the elements required of an ideal system, and none achieve both satisfactory reliability and validity simultaneously. One alternative approach was to use two or more classification systems concurrently, leveraging their respective strengths and compensating for their weaknesses to provide more optimal guidance for clinical planning. Therefore, this article reviewed the commonly used Pilon fracture classification systems for clinical reference and to support further research.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 9","pages":"946-53"},"PeriodicalIF":0.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Digital research on 3D-printed personalized wing-shaped anatomical plate for the distal end of clavicle fracture].","authors":"Zhihui Zhao, Jiakai Zhang, Junlong Wu, Yi Zheng","doi":"10.12200/j.issn.1003-0034.20250667","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20250667","url":null,"abstract":"<p><strong>Objective: </strong>To develop an individualized anatomical plate for extreme distal clavicle fractures using 3D metal printing technology, and improve adaptability of internal fixation and accuracy of screw placement.</p><p><strong>Methods: </strong>A CT dataset of clavicle (with a layer thickness of 1 mm) from a 52-year-old healthy male volunteer was selected. The clavicle specimen model was reconstructed using Mimics 15.01, and an anatomical plate with wing-like structure for the extremely distal fracture of the clavicle was designed in NX 12.0. Import stl data into 3D printing machine to fabricate a 1∶1 anatomical plate for the distal end of clavicle and a clavicle model. Test the fit of the plate in vitro, evaluate accuracy of screw placement through X-ray and CT scans, and record the time and cost for model printing, screw path planning, plate fabrication, and cost.</p><p><strong>Results: </strong>The 3D-printed distal wing-shaped plate for clavicle had a good fit with the distal end of clavicle. All screws were located within the preset screw channels and did not penetrate shoulder-clavicle joint surface. The time for model printing, nail track planning, and steel plate fabrication was 125, 20, and 310 min respectively, and the total cost was approximately 3, 000 yuan.</p><p><strong>Conclusion: </strong>The 3D metal printing could provide an accurate fixation solution for fractures at the distal end of clavicle by customizing the personalized anatomical plate for the distal end of clavicle.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 9","pages":"927-30"},"PeriodicalIF":0.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Progress on the treatment of Achilles tendon rupture].","authors":"Weifan Ren, Dawei Xin, Zhenshuang Yue, Zhenfei Xiong","doi":"10.12200/j.issn.1003-0034.20250093","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20250093","url":null,"abstract":"<p><p>Achilles tendon rupture is an important research topic in the field of sports medicine. Its imaging diagnosis, treatment methods, rehabilitation strategies, and prognosis assessment have always been the focus of academic attention. MRI examination is widely used in diagnosing Achilles tendon rupture, but it has disadvantages such as high cost, long examination time, and metal contraindications. Ultrasound examination has the advantages of being non-invasive, low cost, comfortable, and portable, and it also has high specificity and accuracy, which has significant application value. The treatment methods for Achilles tendon rupture mainly include conservative treatment and surgical treatment. The choice of treatment strategy should be comprehensively considered based on the patient's age, degree of injury, physical condition, and rehabilitation compliance. The advantage of conservative treatment is that it costs less and avoids incision infection or poor healing, but it has a higher re-rupture rate. The advantages of open surgery include direct visualization of the tendon end and application of correct tension to restore the tendon length, but it is prone to incision infection and sural nerve injury. Minimally invasive surgery has the advantages of small incision and low complications, and is increasingly being applied in clinical practice. Regardless of the treatment plan adopted, systematic rehabilitation plays a crucial role in improving functional prognosis. In my opinion, the current research focus is on the improvement of minimally invasive surgical methods, the development and clinical application of new anti-adhesion technologies, and the optimization design of personalized rehabilitation plans. At the same time, future research needs to further explore how to reduce the incidence of complications and improve the postoperative quality of life of patients through surgical method innovation and the application of biomaterials.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 9","pages":"959-64"},"PeriodicalIF":0.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Mid-term efficacy analysis of single-inlet dual-channel core decompression combined with structural bone support in the treatment of early non-traumatic femoral head necrosis].","authors":"Ju'an Yue, Hao Fu, Xiaozhong Guo, Randong Wang, Bing Li, Jiao Chen, Wangyan Liu, Fengnian Zhao","doi":"10.12200/j.issn.1003-0034.20251187","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20251187","url":null,"abstract":"<p><strong>Objective: </strong>To explore mid-term clinical efficacy of single-approach dual-channel core decompression combined with structural bone grafting surgery in treating early non-traumatic osteonecrosis of the femoral head(ONFH), as well as influencing factors of postoperative hip joint survival rate.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 130 hips of 87 patients with ONFH who underwent single-inlet dual-channel core decompression combined with structural bone support bone grafting from October 2016 to September 2020. Among them, there were 75 males and 12 females;aged from 18 to 59 years old with an average of (37.53±10.31) years old;44 patients were unilateral and 43 patients were bilateral. Harris hip score (HHS), the rate of imaging progression, and failure rate(the surgery was considered a failure if total hip arthroplasty was eventually performed) were observed;the survival curves were plotted using Kaplan-Meier method, Log-rank test was used for comparisons between groups. Cox proportional hazards regression model was employed to analyze independent risk factors, including age, Association Research Circulation Osseous(ARCO) staging, 2021 ARCO classification, China-Japan Friendship Hospital (CJFH) classification, and Japanese Investigation Committee(JIC) classification.</p><p><strong>Results: </strong>All patients were followed up, the duration ranged from 6 to 76 months, with an average of(53.13±19.06) months. HHS was increased from (78.73±11.52) before operation to (91.70±3.88) at the latest follow-up, and the difference was statistically significant(<i>t</i>=3.305, <i>P</i>=0.008). The imaging results showed at the last follow-up, 21 patients with femoral head collapse had progressed, with progression rate of 16.15%;among 130 hip joints, 31 patients' hip surgery failed and eventually underwent total hip arthroplasty (THA), with a failure rate of 23.85%. The factors contributing to failure of surgery included age (<i>χ</i><sup>2</sup>=10.489, <i>P</i>=0.003), ARCO classification (<i>χ</i><sup>2</sup>=19.244, <i>P</i>=0.000), JIC classification (<i>χ</i><sup>2</sup>=21.734, <i>P</i>=0.000), and CJFH classification (<i>χ</i><sup>2</sup>=0.979, <i>P</i>=0.000). Age more than 40 years old (<i>P</i>=0.011), ARCO classification in 2021 (<i>P</i>=0.048), JIC classification (<i>P</i>=0.014), and CJFH classification (<i>P</i>=0.037) were independent risk factors for surgical failure.</p><p><strong>Conclusion: </strong>Single-inlet dual-channel core decompression combined with structural bone support bone grafting is a highly effective mid-term clinical treatment for hip preservation surgery. To improve the survival rate of the hip joint, it is necessary to strictly adhere to the surgical indications. Patients with ONFH aged 40 years old or above, type 3 according to ARCO in 2021, type C2 according to JIC, and type L3 according to CJFH, are not recommended to undergo this surgical procedure.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 9","pages":"880-7"},"PeriodicalIF":0.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Application of 3D printing technology in minimally invasive treatment of Sanders typeⅡ-Ⅲ calcaneal fractures].","authors":"Yimeng Wu, Dawei Zhao, Guangrong Yu, Xiaoyan Mao, Haiting Li, Yingjie Zhu","doi":"10.12200/j.issn.1003-0034.20250498","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20250498","url":null,"abstract":"<p><strong>Objective: </strong>To explore clinical efficacy of 3D-printed guide plates combined with expansion screw internal fixation in treating Sanders typeⅡand Ⅲ calcaneal fractures.</p><p><strong>Methods: </strong>From March 2021 to October 2024, 60 patients with Sanders typeⅡand Ⅲ calcaneal fractures were admitted and divided into 3D printing group and closed reduction group based on different surgical methods. There were 32 patients in 3D printing group, including 28 males and 4 females;aged from 31 to 43 years old with an average of (37.2±4.1) years old;the course of disease ranged from 1.2 to 5.0 days with an average of (3.8±1.8) days;17 patients with typeⅡand 15 patients with type Ⅲ according to Sanders classification;treated with closed reduction with screws using custom-made guides printed by 3D technology in combination with expanders. There were 28 patients in closed reduction group, including 25 males and 3 females;aged from 29 to 41 years old with an average of (36.0±5.3) years old;the course of disease ranged from 2.8 to 4.8 days with an average of (4.1±1.2) days;16 patients with typeⅡand 12 patients with type Ⅲ according to Sanders classification;treated with simple distraction device for closed reduction and screw fixation. Operation time, fluoroscopy frequency, blood loss, the changes in Böhler angle, Gissane angle were compared;preoperative and postoperative calcaneal width of talus, American Orthopaedic Foot and Ankle Society (AOFAS) ankle-hindfoot score at 6 months were compared.</p><p><strong>Results: </strong>Both groups of patients were followed up for 6 to 10 months with an average of (8.4±0.9) months. There were no complications such as infection, skin necrosis, or non-healing of fractures in either group after operation. Operation time, intraoperative blood loss and fluoroscopy frequency of 3D printing group were (51.2±6.8) min, (22.4±5.3) mL and(18.3±4.2) respectively, which were all better than those of closed reduction group(63.5±8.2) min, (39.6±7.1) mL, (34.5±5.8), and the differences were statistically significant (<i>P</i><0.05). Preoperative Böhler angle, Gissane angle and calcaneal width of 3D printing group and closed reduction group were[(13.9±6.2)° <i>vs.</i> (12.6±5.8)°], [(150.2±3.8)° <i>vs.</i> (149.3±4.5)°], and [(44.2±1.8) mm <i>vs.</i> (42.8±1.6) mm] respectively;and [(27.5±7.1)° <i>vs.</i> (26.8±6.9)°], [(125.7±2.1)° <i>vs.</i> (123.4±1.5)°], and [(38.2±1.2) mm <i>vs.</i> (37.5±0.9) mm] respectively at 6 months after operation;Böhler angle, Gissane angle and calcaneal width of both groups at 6 months after operation were significantly improved compared with those of before operation (<i>P</i><0.05). Postoperative AOFAS ankle-hindfoot scores of both groups at 6 months showed significant improvement compared to those of before operation (<i>P</i><0.05), and there was no statistically significant difference between two groups (<i>P</i>>0.05). According to postoperative AOFAS ankle-hindfoot scores at 6 m","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 9","pages":"888-94"},"PeriodicalIF":0.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[New insights into osteonecrosis of the femoral head therapy from dual perspectives of bone homeostasis and mechanical reconstruction].","authors":"Qidong Zhang","doi":"10.12200/j.issn.1003-0034.20260739","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20260739","url":null,"abstract":"","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 9","pages":"857-61"},"PeriodicalIF":0.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minglan Xu, Jun Shen, Pengfei Sun, Jianye Wang, Chi Zhao, Bingxin Kang, Xiaoxue Hu, Lianbo Xiao
{"title":"[A randomized controlled study on application of giant needle electroacupuncture at different times for improving pain and joint function after total knee arthroplasty].","authors":"Minglan Xu, Jun Shen, Pengfei Sun, Jianye Wang, Chi Zhao, Bingxin Kang, Xiaoxue Hu, Lianbo Xiao","doi":"10.12200/j.issn.1003-0034.20250200","DOIUrl":"10.12200/j.issn.1003-0034.20250200","url":null,"abstract":"<p><strong>Objective: </strong>To explore clinical efficacy of applying giant needle electroacupuncture at different times in improving pain and joint function after total knee arthroplasty(TKA).</p><p><strong>Methods: </strong>A total of 120 patients who underwent TKA from July 2022 to March 2023 were included. They were divided into preoperative electro-acupuncture group, postoperative electro-acupuncture group, and control group according to different intervention times of electro-acupuncture, and 38 patients in each group, 2 patients from each group were dropped out, resulting in a final inclusion of 114 patients. In preoperative electro-acupuncture group, there were 7 males and 31 females;aged from 60 to 80 years old with an average of (72.0±5.8) years old;electro-acupuncture was performed on Weishu acupoint (ST32), Zusanli acupoint (ST36), Yinlingquan acupoint (SP9), and Yanglingquan acupoint (GB34) of non-operated lower limbs at 1 day before operation, 30 min before anesthesia induction, and 1 to 3 days after operation. In postoperative electro-acupuncture group, there were 9 males and 29 females;aged from 60 to 80 years old with average of (71.6±6.7) years old;the same acupuncture points and parameters were treated 1 to 3 days after operation. In control group, there were 6 males and 32 females;aged from 60 to 80 years old with an average of (71.6±7.1) years old;and were received pseudo-electroacupuncture treatment. Pain was scored at rest and during movement respectively before operation and 4 to 7 days after operation by using numerical rating scale at rest (NRSR) and numerical rating scale with movement (NRSM), joint function was evaluated by active range of motion (AROM) of knee joint, Hospital for Special Surgery(HSS) knee score, and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC).</p><p><strong>Results: </strong>A total of 114 patients were followed up, with the follow-up period being 7 days after operation. There were no statistically significant differences in preoperative NRSR, NRSM, AROM, HSS, and WOMAC scores among three groups (<i>P</i>>0.05). There were statistically significant differences among three groups of NRSR and NRSM scores on the 4th to 7th day after operation (<i>P</i><0.05). The comparison of AROM among three groups on the 7th day after operation showed statistically significant difference (<i>P</i><0.05), while there was no statistically significant difference when comparing the data from 4 to 6 days after operation (<i>P</i>>0.05). The comparisons of HSS and WOMAC scores on the 7th day after operation among three groups showed statistically significant differences (<i>P</i><0.05). NRSR scores of pre-electroacupuncture group on the 4th to 6th days after operation were 2.0(1.0, 2.3), 1.0(1.0, 2.0), and 1.0(1.0, 2.0) respectively, which were lower than those of post-electroacupuncture group 3.0(2.0, 4.0), 2.0(1.0, 3.0), 2.0(1.0, 2.0), and the differences were statistically significant (<i>P</","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 9","pages":"903-10"},"PeriodicalIF":0.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Junming Chen, Zaishi Zhu, Chenghan Xu, Zeling Huang, Bo Xu, Yuwei Li
{"title":"[Systematic review and Meta-analysis of core decompression combined with bone marrow transplantation versus core decompression alone in the treatment of osteonecrosis of the femoral head].","authors":"Junming Chen, Zaishi Zhu, Chenghan Xu, Zeling Huang, Bo Xu, Yuwei Li","doi":"10.12200/j.issn.1003-0034.20251204","DOIUrl":"10.12200/j.issn.1003-0034.20251204","url":null,"abstract":"<p><strong>Objective: </strong>To compare clinical efficacy and safety of core decompression combined with bone marrow transplantation versus core decompression alone in the treatment of osteonecrosis of the femoral head (ONFH) through systematic evaluation and meta-analysis.</p><p><strong>Methods: </strong>In accordance with the preferred reporting items for systematic reviews and Meta-analyses (PRISMA) principles, a search was conducted in PubMed, Web of Science, Cochrane Library, Embase, China National Knowledge Infrastructure (CNKI), VIP Database, Wanfang Database, and Chinese Biomedical Literature Database for clinical randomized controlled trial (RCT) and non-randomized controlled trial (nRCT) related to core decompression combined with bone marrow transplantation and simple core decompression for ONFH published from January 2000 to September 2025. After literature screening, data extraction and quality evaluation, Review Manager 5.4 and R 4.4.2 software were used to compare visual analogue scale (VAS) for hip joint pain, Harris score for hip joint, the progression of the disease on imaging, the rate of total hip replacement, and the incidence of adverse reactions.</p><p><strong>Results: </strong>A total of 15 relevant studies were finally included, consisting of 14 RCTs and 1 nRCT, involving 607 patients and 693 hip lesions. Among them, 369 hips were in core decompression combined with bone marrow transplantation group, and 324 hips were in simple core decompression group. Meta-analysis result showed there were statistically significant differences between two groups in terms of Harris score for hip joint[6 months after operation, <i>MD</i>=4.57, 95%<i>CI</i>(2.62, 6.53), <i>P</i><0.000 01;12 months after operation, <i>MD</i>=8.18, 95%<i>CI</i>(6.81, 9.55), <i>P</i><0.000 01;24 months after operation, <i>MD</i>=11.63, 95%<i>CI</i>(10.40, 12.86), <i>P</i><0.000 01], imaging disease progression[<i>OR</i>=0.24, 95%<i>CI</i>(0.15, 0.41), <i>P</i><0.000 01], and total hip replacement rate [<i>OR</i>=0.28, 95%<i>CI</i>(0.13, 0.64), <i>P</i>=0.003]. The comparisons of VAS[<i>MD</i>=-0.43, 95%<i>CI</i>(-1.58, 0.71), <i>P</i>=0.46] and the incidence of adverse reactions[<i>OR</i>=2.48, 95%<i>CI</i>(0.83, 7.42), <i>P</i>=0.10] showed no statistically significant differences.</p><p><strong>Conclusion: </strong>The safety of core decompression combined with bone marrow transplantation in the treatment of ONFH is comparable to that of simple core decompression. Moreover, it has more advantages in improving hip joint function, delaying disease progression, and reducing the need for total hip replacement in the end stage. This provides a better option for the hip preservation treatment of early ONFH.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 9","pages":"931-40"},"PeriodicalIF":0.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Ultrasound-guided needle-knife release of transverse carpal ligament for the treatment of fibrosis in carpal tunnel syndrome].","authors":"Yunnan Li, Qiaoyin Zhou, Shen Luo, Weilin Lin, Ying Cao, Xinyao Huang","doi":"10.12200/j.issn.1003-0034.20250751","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20250751","url":null,"abstract":"<p><strong>Objective: </strong>To explore effects of ultrasound-guided needle-knife dissection of transverse carpal ligament on morphology, function and fibrosis level of the median nerve and transverse carpal ligament in rabbits with carpal tunnel syndrome.</p><p><strong>Methods: </strong>Forty-eight clean-grad male New Zealand rabbits aged 5 to 6 months were selected, with a body weight of (3.0±0.5) kg. They were randomly divided into blank group, model group, ultrasound group, non-ultrasound group, pseudo-needle knife group, and hormone group, with 8 rabbits in each group. All groups except blank group were underwent modeling performed by injecting 10% glucose solution into wrist canal. The modeling and intervention were conducted once every 7 days. After 4 rounds of modeling, except for control group and model group, all other groups were received intervention for 4 times. Ultrasound group was performed needle-knife dissection of wrist transverse ligament under ultrasound guidance. Non-ultrasound group was adopted the same surgical procedure as ultrasound group but without using ultrasound. The sham needle-knife group was used ultrasound guidance to reach wrist transverse ligament but did not perform dissection. The hormone group injected glucocorticoids into wrist transverse ligament and the median nerve under ultrasound guidance. At 30 days after intervention, ultrasound was used to measure the thickness of palmar ligament and median nerve;electromyography was employed to measure the conduction velocity, latency and action potential of median nerve to assess function of the median nerve;the transverse ligament of wrist and the median nerve were subjected to hematorglineosin(HE) staining to observe tissue morphology. The concentrations of transforming growth factor β1(TGF β1), connective tissue growth factor(CTGF), and collagen typeⅠ(ColⅠ) and collagen type Ⅲ(Col Ⅲ) were detected by enzyme-linked immunosorbent assay (ELISA) to observe the concentrations of fibrosis-related factors. Immunofluorescence was used to detect the relative fluorescence intensity of TGFβ1 in the tissues of the median nerve and the transverse ligament of wrist.</p><p><strong>Results: </strong>Compared with model group, the thickness of the median nerve and palmar ligament in ultrasound group, non-ultrasound group and hormone group decreased, and the differences were statistically significant(<i>P</i><0.05). In terms of electrophysiological examination, ultrasound group, non-ultrasound group and hormone group all showed improvements in the conduction velocity, latency and action potential of the median nerve, and the differences were statistically significant compared with model group(<i>P</i><0.05). In terms of Elisa test, the concentrations of TGFβ1 in ultrasound group, non-ultrasound group and hormone group were lower than those in model group(<i>P</i><0.05). The CTGF level in ultrasound group was decreased, and the difference was statistically significant(<i>P</i><","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 9","pages":"918-27"},"PeriodicalIF":0.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}