Zhongguo gu shang = China journal of orthopaedics and traumatology最新文献

{"title":"[Clinical application and research progress of foot and ankle assistive devices].","authors":"Shutao Zhang, Cheng Chen, Zhongmin Shi","doi":"10.12200/j.issn.1003-0034.20250331","DOIUrl":"10.12200/j.issn.1003-0034.20250331","url":null,"abstract":"<p><p>Foot and ankle assistive devices are a type of external apparatus that improves functional impairment or structural abnormalities of the lower limbs through biomechanics. They act on ankle and musculoskeletal system of foot through customized or standardized structural designs, aiming to alleviate patients' pain, improve gait stability, and delay progression of disease. At present, there are a wide variety of foot and ankle assistive devices in China, but their application in the field is not sufficient. Their main function still remains at long-term immobilization. For diseases such as abnormal lower limb muscle strength after stroke, congenital clubfoot, and congenital flatfoot, there are already various innovative assistive devices that could play a corrective role and improve the lower limb activity function of patients. In recent years, 3D printing technology has been able to achieve both \"static\" and \"dynamic\" correction functions, meeting the evolving process of orthopedic diseases. Meanwhile, the intelligent sensing and real-time feedback system could use algorithms to monitor abnormal gait or pressure distribution in the foot in real time, and adjust the supporting force of the auxiliary device. Based on this, through an overview of common classifications of ankle-foot assistive devices currently available, and by reviewing and summarizing the latest clinical research progress of ankle-foot assistive devices, it is hoped to provide ideas for clinical application.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 6","pages":"637-41"},"PeriodicalIF":0.0,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148309598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical efficacy of closed reduction and percutaneous pinning in the treatment of Lauge-Hansen typeⅡankle fractures with posterior-external rotation].","authors":"Hanwei Kang, Yulin Wang, Ning Li, Yali Hu, Chenlin Wang, Hongwen Xing","doi":"10.12200/j.issn.1003-0034.20250722","DOIUrl":"10.12200/j.issn.1003-0034.20250722","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To explore clinical efficacy of closed reduction and percutaneous pinning technique in treating Lauge-Hansen typeⅡankle fractures with posterior-external rotation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A retrospective analysis was conducted on clinical data of 106 patients with Lauge-Hansen posterior and external rotation typeⅡankle fractures who were admitted from January 2021 to February 2024. The patients were divided into closed reduction and percutaneous pinning internal fixation group (minimally invasive group) and open reduction and internal fixation (ORIF) group based on surgical methods. There were 53 patients in minimally invasive group, included 24 males and 29 females;aged from 32 to 75 years old with an average of (52.40±9.12) years old;27 patients on the left side and 26 patients on the right side. There were 53 patients in ORIF group, included 23 males and 30 females;aged from 30 to 72 years old with average of (51.72±9.65) years old;25 patients on the left side and 28 patients on the right side. Operation time, intraoperative blood loss, hospital stay, and complication rate between two groups were compared. The pain condition was evaluated by visual analogue scale (VAS) at 1, 2, 3, 7 and 30 days after operation;clinical efficacy was evaluated by American Orthopaedic Foot and Ankle Society (AOFAS) ankle-hindfoot score and Olerud-Molander ankle score (OMAS) at 3 and 6 months after operation;ankle joint range of motion at 6 months after operation was recorded and compared.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Both groups of patients were successfully completed operation and followed up. The follow-up period ranged from 9 to 15 months with an average of (12.15±2.37) months. Operation time, hospital stay and intraoperative blood loss in minimally invasive group were (19.09±6.87) min, (10.19±2.91) days and (5.94±3.00) mL respectively, while those in ORIF group were (26.57±6.92) min, (12.58±3.49) days and (12.87±4.65) mL respectively;there were statistically significant differences between two groups (&lt;i&gt;P&lt;/i&gt;&lt;0.05). The comparison of VAS between two groups at 30 days after operation showed no statistically significant difference (&lt;i&gt;P&lt;/i&gt;&gt;0.05). The comparisons of AOFAS ankle-hind foot scores and OMAS scores between two groups at 3 and 6 months after operation also showed no statistically significant differences (&lt;i&gt;P&lt;/i&gt;&gt;0.05). There were no statistically significant differences in ankle joint flexion and extension ranges of motion between the healthy and the affected sides at 6 months after operation (&lt;i&gt;P&lt;/i&gt;&gt;0.05). The differences of internal and external rotation activities in minimally invasive grou were (2.60±1.52)° and(1.36±0.59)°, which were better than those of ORIF group (5.49±1.72)° and (2.57±1.37)°;the differences were statistically significant (&lt;i&gt;P&lt;/i&gt;&lt;0.05). The incidence of complications in minimally invasive group was 5.66%(3/53), which was lower than that in ORIF group 20.75% (11/53), and the diffe","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 6","pages":"546-53"},"PeriodicalIF":0.0,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148309561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Comparison of therapeutic effects of conventional puncture technique and target puncture technique in the treatment of osteoporotic vertebral compression fractures in elderly by vertebroplasty].","authors":"Zhongrui Liu, Dipeng Li, Guanrong Sun, Canfeng Chen, Li Li, Yongfeng Cui","doi":"10.12200/j.issn.1003-0034.20230560","DOIUrl":"10.12200/j.issn.1003-0034.20230560","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To explore clinical efficacy of conventional puncture technique and precise target puncture technique in percutaneous vertebroplasty (PVP) for the treatment of osteoporotic vertebral compression fractures (OVCFs) in elderly.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;From January 2016 to December 2019, 64 elderly patients with OVCFs were treated by PVP technique. According to t different puncture methods, they were divided into conventional puncture technique group (conventional group) and precise target puncture technique group (target group). The conventional group consisted of 31 cases, included 4 males and 27 females, aged from 63 to 93 years old with an average of (75.58±7.98) years;15 patients with thoracic vertebrae and 23 patients with lumbar vertebrae. There were 33 patients in target group, included 4 males and 29 females;aged from 62 to 93 years old with an average of (74.61±8.17) years old;19 patients with thoracic vertebrae and 27 patients with lumbar vertebrae. Operation time, hospital stay, bone cement leakage, number of patients with bone cement leakage, pain visual analogue scale (VAS), and the height of anterior vertebral margin between two groups were observed and compared.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Both of two groups were followed up, and the follow-up period for conventional group ranged from 6 to 8 months with an average of (6.23±1.51) and for target group ranged from 6 to 10 months with an average of (6.76±1.11) months, there was no statistically significant difference in follow-up period between two groups (&lt;i&gt;P&lt;/i&gt;&gt;0.05). There were no statistically significant differences in operation time, hospital stay, bone cement leakage, bone cement injection volume, and VAS before operation and 6 months after operation between two groups (&lt;i&gt;P&lt;/i&gt;&gt;0.05). VAS of target group decreased from (7.36±0.49) points before operation to (1.64±0.49), (1.30±0.47), and (0.82±0.39) points respectively at 1 day, 1 month, and 6 months after operation;VAS of control group decreased from (7.42±0.50) before operation to (1.97±0.18), (1.64±0.49), and (0.94±0.44) respectively at 1 day, 1 month, and 6 months after operation;the differences were all statistically significant (&lt;i&gt;P&lt;/i&gt;&lt;0.05);VAS of target group was lower than that of conventional group at 1 day and 1 month after operation (&lt;i&gt;P&lt;/i&gt;&lt;0.05). Postoperative anterior vertebral height at 3 days and 6 months in target group were (24.04±5.40) mm and (23.71±2.65) mm respectively, while in conventional group were (23.89±4.00) mm and (22.21±3.63) mm respectively;and there were no statistically significant difference in anterior vertebral height between two groups at 3 days after operation (&lt;i&gt;P&lt;/i&gt;&gt;0.05);postoperative anterior vertebral height of target group was higher than that of conventional group at 6 months, and the difference was statistically significant (&lt;i&gt;P&lt;/i&gt;&lt; 0.05).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;PVP puncture technique not only retains advantages of traditi","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 6","pages":"591-7"},"PeriodicalIF":0.0,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148309591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Finite element analysis of traditional treatment methods for osteoporotic vertebral compression fractures].","authors":"Wenchao Li, Pengfei Yu, Zhijia Ma, Guoxu Zhang, Limeng Yang, Hong Guo, Chao Li, Hongwei Li","doi":"10.12200/j.issn.1003-0034.20250656","DOIUrl":"10.12200/j.issn.1003-0034.20250656","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To analyze and compare the treatment of osteoporotic vertebral compression fracture by finite element method, and to explore biomechanical feasibility and advantages of traditional manual therapy for osteoporotic vertebral compression fractures(OVCFs).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A 26-year-old healthy volunteer (heighted 1.8 m, body weighted 85 kg) was selected, simulated and reconstructed OVCFs model (T&lt;sub&gt;11&lt;/sub&gt;-L&lt;sub&gt;2&lt;/sub&gt;), set the degrees of freedom below L&lt;sub&gt;2&lt;/sub&gt; vertebra as \"0\", and then applied four different simulated working conditions for loading to observe stress distribution of model and displacement of the fractured vertebra. Repositioning in hyperextension position, applied a forward 7.5 N·m torque of positive force to X-axis of model fracture vertebra;simple compression repositioning, applied 400 N load perpendicular to Y-axis to fractured vertebra; compression repositioning in hyperextension position, the simulation of position involved applying 7.5 N·m forward torque to X-axis of the model fracture vertebra and 400 N load perpendicular to Y-axis to fractured vertebra; compound manual repositioning, applied 7.5 N·m forward torque to X-axis of model fracture vertebra, then applied 400 N load perpendicular to Y-axis, removed the previous fixation and load, then set the degrees of freedom below L&lt;sub&gt;2&lt;/sub&gt; vertebra to \"0\", and applied 400 N load to L&lt;sub&gt;1&lt;/sub&gt;.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Comparison of equivalent stresses under various loading conditions showed compound manual repositioning (124.35 MPa)&gt; compression repositioning in hyperextension position (101.17 MPa)&gt;repositioning in hyperextension position (95.22 MPa)&gt; simple compression repositioning (31.11 MPa). The stress in repositioning in hyperextension position, compression repositioning in hyperextension position, and compound manual repositioning could concentrate on anterior-middle column of the target vertebra. The stress in simple compression repositioning did not concentrate on the target vertebra and showed obvious dispersion. Comparison of stress peak values showed the stress peak of compound manual repositioning (149.41 MPa)&gt;compression repositioning in hyperextension position (120.54 MPa)&gt;repositioning in hyperextension position (111.32 MPa)&gt;simple compression repositioning(27.60 MPa), the stress peaks of repositioning in hyperextension position, compression repositioning in hyperextension position, and compound manual repositioning were concentrated on anterior-middle column of the target vertebra, while the stress peak of simple pressing reduction was significantly dispersed. Comparison of model displacement showed compound manual repositioning (2.24 mm)&gt;compression repositioning in hyperextension position (2.17 mm)&gt;repositioning in hyperextension position (1.89 mm)&gt;simple compression repositioning(1.24 mm), the model displacements in all these repositioning methods were concentrated on anterior-middle column","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 6","pages":"614-22"},"PeriodicalIF":0.0,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148309531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Progress on mechanism of mitochondrial autophagy in pathogenesis of intervertebral disc degeneration based on PINK1/Parkin signaling pathway].","authors":"Jie Guo, Ling Lei, Hongjing Tian, Tiefeng Guo, Linzhao Luo, Yanjun Zhang","doi":"10.12200/j.issn.1003-0034.20241146","DOIUrl":"10.12200/j.issn.1003-0034.20241146","url":null,"abstract":"<p><p>Intervertebral disc degeneration (IVDD) is one of the main causes of lower back pain. The chronic accumulation of aging and apoptosis of nucleus pulposus cells (NPCs) is believed to be related to IVDD. In recent years, mitochondrial autophagy which as an important clearance mechanism within cells, has gradually attracted attention. The PINK1/Parkin signaling pathway is regarded as the key pathway regulating mitochondrial autophagy, and it plays a significant role in physiological and pathological processes of NPCs. The mechanism by which PINK1/Parkin signaling pathway mediates mitochondrial autophagy could be understood as follows, PINK1, as the sensor for mitochondrial quality regulation, is activated. It recruits and activates Parkin to the mitochondrial membrane through phosphorylation of ubiquitin, and then undergoes Parkin-dependent substrate ubiquitination, recruitment of autophagy receptors, formation of autophagosomes, and fusion with lysosomes, ultimately completing the extremely important autophagy process. Current research indicates that abnormality of PINK1/Parkin signaling pathway may be closely related to IVDD, but the specific mechanism still requires further exploration. The paper explores research progress of mechanism by which mitochondrial autophagy affects IVDD based on PINK1/Parkin signaling pathway, with the aim of providing new strategies and targets for the treatment of IVDD.</p>","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 6","pages":"642-8"},"PeriodicalIF":0.0,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148309568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Value of Wells score combined with D-dimer detection in predicting the risk of deep vein thrombosis before ankle fracture surgery].","authors":"Yongxing Jia, Zhifeng Liang, Hongbo Ren, Yongqi Ye, Yingcai Yang","doi":"10.12200/j.issn.1003-0034.20250848","DOIUrl":"10.12200/j.issn.1003-0034.20250848","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To explore t predictive value of Wells score combined with D-dimer (D-D) test for the risk of deep venous thrombosis(DVT) before ankle fracture surgery.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;From May 2023 to May 2024, clinical data of 80 patients with ankle fractures were retrospective analyzed, included 50 males and 30 females;age from 35 to 69 years old with an average of (52.61±8.91) years old;body mass index (BMI) ranged from 20.5 to 24.9 kg·m&lt;sup&gt;-2&lt;/sup&gt; with an average of (23.41±2.09) kg·m&lt;sup&gt;-2&lt;/sup&gt;;43 patients caused by high-energy injuries and 37 patients by low-energy injuries;30 patients with single ankle fractures and 50 patients with multiple ankle fractures;21 patients had combined vascular and nerve injuries;13 patients had a history of diabetes;the time from injury to medical consultation ranged from 40 to 103 min (69.77±5.53) min;preoperative waiting time ranged from 19 to 38 min with an average of (25.98±10.24) min;preoperative risk assessment and prediction (RAPT) score ranged from 6 to 11points with an average of (8.02±1.87) points. The patients were divided into DVT group (21 patients) and non-DVT group (59 patients) based on whether DVT occurred. Wells scores, D-D levels, thrombin-antithrombin complex (TAT), plasmin-α2-plasmin inhibitor complex (PIC), thrombomodulin (TM), and tissue plasminogen activator-inhibitor complex (t-PAIC) between two groups were conducted by Pearson correlation analysis. Logistic regression was used to analyze risk factors for DVTin ankle fractures, receiver operating characteristic curve (ROC) was employed to evaluate diagnostic value of Wells score and D-D levels for DVT of ankle joint.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;There were statistically significant differences in proportion of high-energy injuries, the proportion of combined nerve and vascular injuries, the time from injury to medical consultation, Wells score, D-D, TAT, PIC, TM, and t-PAIC between non-DVT group and DVT group (&lt;i&gt;P&lt;/i&gt;&lt;0.05). Pearson correlation analysis results showed TAT (&lt;i&gt;r&lt;/i&gt;=0.291, &lt;i&gt;P&lt;/i&gt;=0.009), PIC (&lt;i&gt;r&lt;/i&gt;=0.254, &lt;i&gt;P&lt;/i&gt;=0.023), TM (&lt;i&gt;r&lt;/i&gt;=0.469, &lt;i&gt;P&lt;/i&gt;&lt;0.001), and t-PAIC (&lt;i&gt;r&lt;/i&gt;=0.598, &lt;i&gt;P&lt;/i&gt;&lt;0.001) were positively correlated with Wells score;TAT (&lt;i&gt;r&lt;/i&gt;=0.308, &lt;i&gt;P&lt;/i&gt;=0.005), PIC (&lt;i&gt;r&lt;/i&gt;=0.340, &lt;i&gt;P&lt;/i&gt;=0.002), TM (&lt;i&gt;r&lt;/i&gt;=0.501, &lt;i&gt;P&lt;/i&gt;&lt;0.001), and t-PAIC (&lt;i&gt;r&lt;/i&gt;=0.650, &lt;i&gt;P&lt;/i&gt;&lt;0.001) were positively correlated with D-D level. Logistic regression analysis showed high-energy injury [&lt;i&gt;OR&lt;/i&gt;=3.390, 95%&lt;i&gt;CI&lt;/i&gt;(1.950, 4.713), &lt;i&gt;P&lt;/i&gt;=0.004], combined with vascular and nerve injury[&lt;i&gt;OR&lt;/i&gt;=2.169, 95%&lt;i&gt;CI&lt;/i&gt;(1.494, 3.610), &lt;i&gt;P&lt;/i&gt;&lt;0.001], elevated TAT level[&lt;i&gt;OR&lt;/i&gt;=3.965, 95%&lt;i&gt;CI&lt;/i&gt;(2.569, 5.474), &lt;i&gt;P&lt;/i&gt;&lt;0.001], increased Wells score[&lt;i&gt;OR&lt;/i&gt;=1.233, 95%&lt;i&gt;CI&lt;/i&gt;(0.905, 1.761), &lt;i&gt;P&lt;/i&gt;=0.032], and elevated D-D level[&lt;i&gt;OR&lt;/i&gt;=2.087, 95%&lt;i&gt;CI&lt;/i&gt;(0.356, 3.881), &lt;i&gt;P&lt;/i&gt;&lt;0.001] were all risk factors for the occurrence of DVT after ankle fracture surgery","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 6","pages":"567-72"},"PeriodicalIF":0.0,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148309587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Current clinical application status and decision-making considerations of internal fixation materials for ankle fractures].","authors":"Liangzhi Gong, Zhongmin Shi","doi":"10.12200/j.issn.1003-0034.20260463","DOIUrl":"https://doi.org/10.12200/j.issn.1003-0034.20260463","url":null,"abstract":"","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 6","pages":"533-6"},"PeriodicalIF":0.0,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148309550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Potential mechanism of <i>Peiyuan Fumai</i> decoction() in regulating P-selectin/ P-selectin glycoprotein ligand-1 pathway for prevention and treatment of thrombosis after total knee arthroplasty].","authors":"Yuanyuan Li, Siye Liu, Yanbai Chen, Hai Tang, Lin Jing, Mingjiang He, Weikai Qin, Qi Yan, Hongmei Zhang","doi":"10.12200/j.issn.1003-0034.20250843","DOIUrl":"10.12200/j.issn.1003-0034.20250843","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To explore effect of &lt;i&gt;Peiyuan Fubai&lt;/i&gt; decoction ()on P-selectin/P-selectin glycoprotein ligand-1 (PSGL-1) pathway after total knee arthroplasty(TKA).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;From May 2024 to April 2025, 68 patients who underwent TKA were selected and divided into combined group and western medicine group based on different treatment methods. There were 34 patients in western medicine group, including 7 males and 27 females;aged from 54 to 79 years old with an average of (67.44±5.34) years old;12 patients with grade Ⅲ and 22 patients with grade Ⅳ according to Kellgren-Lawrance(K-L) grade;oral rivaroxaban tablets were started 12 h after surgery and continued until 28 days after surgery. There were 34 patients in combined group, including 4 males and 30 females;aged from 59 to 83 years old with an average of (68.32±5.51) years old;10 patients with grade Ⅲ and 24 patients with grade Ⅳ according to K-L grade; &lt;i&gt;Peiyuan Fubai&lt;/i&gt; decoction ()was orally administered starting from the first day until 28 days after surgery on the basis of western medicine group. The knee joint function was evaluated by visual analogue scale (VAS) and Hospital for Special Surgery (HSS) score before operation and 3, 7, 14, and 42 days after operation;the changes in hemoglobin (Hb), platelet count (PLT), activated partial thromboplastin time (APTT), and prothrombin time (PT) were compared between two groups;the expressions of P-selectin, PSGL-1, histone H3 citrullination (H3Cit), and von Willebrand factor (vWF) in plasma between two groups were compared before operation, 1 and 7 days after operation, and postoperative complications were recorded and compared.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Both groups were followed up for 6 weeks. At 7 days after operation, VAS and HSS scores of combined group were 3.00 (2.00, 4.00) and (66.71±5.37) points respectively, which were better than those of western medicine group 4.00 (3.00, 5.00) and (64.03±5.57) points, and the differences were statistically significant (&lt;i&gt;P&lt;/i&gt;&lt;0.05). Hb of combined group at 7, 14, and 42 days after operation were (110.09±13.21), (113.19±12.08), and (129.58±12.50) g·L&lt;sup&gt;-1&lt;/sup&gt; respectively, while those of western medicine group were (106.91±12.88), (111.72±10.29), and (131.71±12.64) g·L&lt;sup&gt;-1&lt;/sup&gt; respectively;postoperative Hb of both groups at 7 and 14 days were lower than those before operation and 42 days after operation, and the differences were statistically significant (&lt;i&gt;P&lt;/i&gt;&lt;0.05). Postoperative PLT levels of combined group at 7, 14, and 42 days were(234.12±74.03), (292.09±71.32), and 217.50 (185.75, 248.75) × 10&lt;sup&gt;9&lt;/sup&gt;·L&lt;sup&gt;-1&lt;/sup&gt;, respectively;while western medicine group were (246.03±56.84), (322.06±78.72), and 213.00 (183.50, 257.50)×10&lt;sup&gt;9&lt;/sup&gt;·L&lt;sup&gt;-1&lt;/sup&gt;, respectively;postoperative PLT levels of both groups at 14 days were higher than those before operation, 7 and 42 days after operation, and the differences were statistically si","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 6","pages":"573-80"},"PeriodicalIF":0.0,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148309534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Related factors and analysis of prevention strategies for functional ankle instability after ankle fracture surgery].","authors":"Jianjiang Wei, Qiang Chen, Zhankui Jin, Ziyu Zhou","doi":"10.12200/j.issn.1003-0034.20251112","DOIUrl":"10.12200/j.issn.1003-0034.20251112","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To explore related factors and preventive strategies of functional ankle instability (FAI) in patients with ankle fracture (AF) after surgery.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Clinical data of 348 patients with atrial fibrillation (AF) who underwent surgical treatment from January 2022 to September 2023 were retrospective analyzed, including 143 males and 205 females;aged 65 years or above for 150 patients, and younger than 65 years old for 198 patients;body mass index(BMI) of≥24 kg·m&lt;sup&gt;-2&lt;/sup&gt; for 217 patients, and BMI&lt;kg·m&lt;sup&gt;-2&lt;/sup&gt; for 131 patients. All patients were divided into unstable group(71 patients) and stable group (277 patients) based on whether FAI occurred at 1 year after operation. The occurrence of FAI was statistically analyzed;gender, age, BMI, injury cause, smoking history, drinking history, hypertension, diabetes, posterior malleolus fracture Haraguchi classification, the time from injury to operation, proportion of fracture fragments on joint surface, combined ankle dislocation, deltoid ligament injury, surgical method, postoperative complications, whether there was nerve injury during operation, whether calcaneal traction was performed, and the start time of rehabilitation between two groups were compared. Using multivariate Logistic regression analysis was identified the risk factors for the occurrence of FAI after AF.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 348 patients who underwent AF were followed up for 1 year after operation. Among them, 71 patients developed FAI, with an incidence rate of 20.40%. The proportions of patients in unstable group who were≥65 years old, Haraguchi typeⅡposterior malleolus fractures, a post-injury to surgery time of≥8 h, fracture block occupying ≥25% of joint surface, had combined ankle dislocation, treated with tension screws, had infection or incision dehiscence, and start-to-rehabilitation time of ≥7 days were all higher than those in stable group, and the differences were statistically significant (&lt;i&gt;P&lt;/i&gt;&lt;0.05). Multivariate Logistic regression analysis showed age above 65 years old [&lt;i&gt;OR&lt;/i&gt;=2.221, 95%&lt;i&gt;CI&lt;/i&gt;(1.207, 4.086), &lt;i&gt;P&lt;/i&gt;=0.010], posterior malleolar fracture Haraguchi classification typeⅡ[&lt;i&gt;OR&lt;/i&gt;=2.664, 95%&lt;i&gt;CI&lt;/i&gt; (1.718, 4.133), &lt;i&gt;P&lt;/i&gt;&lt;0.001], fracture block occupying≥25% of joint surface [&lt;i&gt;OR&lt;/i&gt;=1.902, 95%&lt;i&gt;CI&lt;/i&gt;(1.241, 2.916), &lt;i&gt;P&lt;/i&gt;=0.003], combined with ankle joint dislocation [&lt;i&gt;OR&lt;/i&gt;=2.385, 95%&lt;i&gt;CI&lt;/i&gt;(1.330, 4.276), &lt;i&gt;P&lt;/i&gt;=0.004], and the start of rehabilitation time≥7 days [&lt;i&gt;OR&lt;/i&gt;=1.972, 95% &lt;i&gt;CI&lt;/i&gt;(1.296, 2.999), &lt;i&gt;P&lt;/i&gt;=0.002] were independent risk factors for FAI after AF (&lt;i&gt;P&lt;/i&gt;&lt;0.05).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Age above 65 years old, Haraguchi classification of posterior malleolar fracture for typeⅡ, fracture fragment occupying≥25% of the joint surface, combined with ankle joint dislocation, and the start of rehabilitation time being≥7 days are independent risk factors for FAI after ","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 6","pages":"597-602"},"PeriodicalIF":0.0,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148309553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Application of vacuum sealing drainage combined with antibiotic bone cement in Gustilo type Ⅲ open ankle fractures].","authors":"Chunming Hu, Xiaofeng Xue, Baoping Liang, Jianjun Niu","doi":"10.12200/j.issn.1003-0034.20250614","DOIUrl":"10.12200/j.issn.1003-0034.20250614","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To investigate clinical efficacy of vacuum sealing drainage (VSD) combined with antibiotic bone cement in treating Gustilo type Ⅲ open ankle fractures.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;From December 2022 to December 2024, 120 patients with Gustilo type Ⅲ open fractures of ankle were treated, and were divided into control group and VSD group according to treatment methods. In control group, there were 58 patients, including 35 males and 23 females;aged from 25 to 58 years old with an average of (45.93±12.82) years old;14 patients with type Ⅲ A, 27 patients with type Ⅲ B, and 17 patients with type Ⅲ C according to Gustilo classification;treated with VSD. In VSD group, there were 62 patients, including 41 males and 21 females;aged from 23 to 58 years old with an average of (45.24±13.05) years old;16 patients with type Ⅲ A, 31 patients with type Ⅲ B, and 15 patients with type Ⅲ C according to Gustilo classification;treated with VSD combined with antibiotic bone cement. The wound healing time, fracture healing time, hospital stay, and postoperative complications between two groups were recorded and compared. The changes in white blood cell count (WBC), neutrophil percentage (NEU), C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were compared between two groups before operation and 1 month after operation. The secretions from patients' wounds were collected for isolation, culture and identification of pathogenic bacteria before operation, 7 and 14 days after operation. The clinical efficacy was evaluated by using American Orthopaedic Foot and Ankle Society (AOFAS) ankle function score to assess recovery of ankle joint function at 6 months after operation.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;All patients were followed up for 8 to 12 months with average of (9.3±2.6) months. The wound healing time, fracture healing time and hospital stay in VSD group were (26.7±4.2) days, (6.9±1.3) months and (30.8±4.7) days respectively, which were better than those in control group (32.3±5.6) days, (8.7±1.8) months, (35.6±5.1) days, and the differences were statistically significant(&lt;i&gt;P&lt;/i&gt;&lt;0.05). At 1 month after operation, the levels of WBC, NEU, ESR and CRP in VSD group were(7.3±1.2) × 10&lt;sup&gt;9&lt;/sup&gt;·L&lt;sup&gt;-1&lt;/sup&gt;, (60.6±5.7)%, (17.9±4.8) mm·h&lt;sup&gt;-1&lt;/sup&gt; and (7.1±1.8) mg·L&lt;sup&gt;-1&lt;/sup&gt; respectively, which were better than those in control group (9.6±1.5)×10&lt;sup&gt;9&lt;/sup&gt;·L&lt;sup&gt;-1&lt;/sup&gt;, (67.8±6.3)%, (26.8±5.3) mm·h&lt;sup&gt;-1&lt;/sup&gt;, (10.6±3.2) mg·L&lt;sup&gt;-1&lt;/sup&gt;, and the differences were statistically significant between two groups(&lt;i&gt;P&lt;/i&gt;&lt;0.05). Among 97 patients with preoperative wound infections, a total of 132 pathogenic bacteria were isolated. The main species were escherichia coli (37, 28.0%), staphylococcus aureus (24, 18.2%), and pseudomonas aeruginosa (19, 14.4%). The pathogen clearance rate at 14 days after operation in VSD group (100%, 50/50) was higher than that in control group (63.8%, 30/47), and the difference ","PeriodicalId":23964,"journal":{"name":"Zhongguo gu shang = China journal of orthopaedics and traumatology","volume":"39 6","pages":"560-6"},"PeriodicalIF":0.0,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148309588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}