World Journal of Clinical Cases最新文献

{"title":"Comprehensive epidemiological assessment of trauma incidents at a level I trauma center.","authors":"Zhao-Yin Su, Hui Wei, Wei-Ning Wang, Yi-Feng Lin, Yu-Li He, Yao Liu, Ru-Bing Lin, Ya-Tao Liu, Nerich Michael","doi":"10.12998/wjcc.v12.i35.6808","DOIUrl":"10.12998/wjcc.v12.i35.6808","url":null,"abstract":"<p><strong>Background: </strong>The continuous development of social and economic progress and ongoing enhancement of infrastructure construction has led to drastic changes in the occurrence of trauma.</p><p><strong>Aim: </strong>To analyze the epidemiological characteristics of trauma in Lanzhou City to provide theoretical references for improving quality of trauma care.</p><p><strong>Methods: </strong>A retrospective analysis of clinical data from 16585 trauma patients treated at the First Hospital of Lanzhou University Trauma Center from November 1, 2021 to October 31, 2023 was conducted. Data including age, sex, time of trauma, cause of trauma, and major injured body parts were statistically analyzed.</p><p><strong>Results: </strong>A total of 18235 patients were admitted, with complete data for 16585 cases. Of these, 9793 were male and 6792 were female (male-to-female ratio of 1.44:1). The peak times for trauma occurrence were 10 AM-12 PM and 6-10 PM, and the peak months were from May to October. The leading causes of trauma were falls (45.32%), other trauma (15.88%), road traffic accidents (15.15%), violence (10.82%), cutting/stabbing (9.41%), mechanical injuries (2.65%), winter sports injuries (0.36%), animal bites (0.22%), burns (0.09%), and electrical injuries (0.02%). The distribution of majorly injured body parts showed statistical significance, with limbs/skin being the most affected followed by the head/neck, chest/abdomen, and back.</p><p><strong>Conclusion: </strong>Medical institutions and government agencies can implement preventive measures and policies based on the characteristics of trauma determined in this study to enhance the quality and level of trauma care.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 35","pages":"6808-6814"},"PeriodicalIF":1.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Update on the aetiopathogenesis of obstructive sleep apnea: Role of inflammatory and immune mediated mechanisms.","authors":"Deb Sanjay Nag, Koshy Varghese, Amlan Swain, Roushan Patel, Seelora Sahu, Merina Sam","doi":"10.12998/wjcc.v12.i35.6754","DOIUrl":"10.12998/wjcc.v12.i35.6754","url":null,"abstract":"<p><p>Obstructive sleep apnea (OSA) is often a lifestyle disease associated with obesity, which is rapidly evolving as a major health concern with diverse multisystemic implications. To prevent and mitigate its adverse effects and reduce its burden on society, its aetiopathogeneses must be precisely understood. Numerous studies focusing on the range of diverse anatomic, functional, and lifestyle factors have already been carried out to determine the possible contributory roles of these factors in OSA. Recently, evidence to validate the role of inflammatory pathways and immune mechanisms in the aetiopathogeneses of OSA is being developed. This allows for further research and translation of such knowledge for targeted therapeutic and preventive interventions in patients with or who are at risk of developing OSA.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 35","pages":"6754-6759"},"PeriodicalIF":1.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>psk1</i> virulence gene-induced pulmonary and systemic tuberculosis in a young woman with normal immune function: A case report.","authors":"Fan Wu, Bin Yang, Yan Xiao, Li-Li Ren, Hong-Yi Chen, Xin-Lan Hu, Yan-Yu Pan, Yu-Sheng Chen, Hong-Ru Li","doi":"10.12998/wjcc.v12.i35.6826","DOIUrl":"10.12998/wjcc.v12.i35.6826","url":null,"abstract":"<p><strong>Background: </strong>Tuberculosis is a chronic infectious disease and an important public health problem. Despite progress in controlling tuberculosis, the incidence of tuberculosis in China is still very high, with 895000 new cases annually. This case report describes the investigation of a case of severe disseminated tuberculosis in a young adult with normal immune function, conducted to ascertain why a <i>Mycobacterium tuberculosis</i> (<i>M. tuberculosis</i>) strain caused such severe disease.</p><p><strong>Case summary: </strong>A previously healthy 28-year-old woman presented to our hospital with a 1-month history of fever and fatigue. She was diagnosed with severe disseminated pulmonary tuberculosis, spinal tuberculosis with paravertebral abscesses, and tuberculous meningitis. <i>M. tuberculosis</i> was isolated from bronchoalveolar lavage fluid. She was treated with standard antituberculous therapy and underwent debridement, bone graft, and internal fixation surgery for spinal tuberculosis. She responded to therapy and regained her ability to walk following the surgery. We analysed the whole-genome sequence of the strain and designated it BLM-A21. Additional <i>M. tuberculosis</i> genomes were selected from the Virulence Factor Database (http://www.mgc.ac.cn/cgi-bin/VFs/genus.cgi?Genus=Mycobacterium) for comparison. An evolutionary tree of the BLM-A21 strain was built using PhyML maximum likelihood software. Further gene analysis revealed that, except for the <i>pks1</i> gene, BLM-A21 had similar virulence genes to the CDC 1551 and H37Rv strains, which have lower dissemination.</p><p><strong>Conclusion: </strong>We speculate that the <i>pks1</i> virulence gene in BLM-A21 may be the key virulence gene responsible for the widespread dissemination of <i>M. tuberculosis</i> infection in this previously healthy adult with normal immune function.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 35","pages":"6826-6833"},"PeriodicalIF":1.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cytokine release syndrome induced by anti-programmed death-1 treatment in a psoriasis patient: A dark side of immune checkpoint inhibitors.","authors":"José Luis Maldonado-García, Ana Fragozo, Lenin Pavón","doi":"10.12998/wjcc.v12.i35.6782","DOIUrl":"10.12998/wjcc.v12.i35.6782","url":null,"abstract":"<p><p>In recent years, cancer immunotherapy has introduced novel treatments, such as monoclonal antibodies, which have facilitated targeted therapies against tumor cells. Programmed death-1 (PD-1) is an immune checkpoint expressed in T cells that regulates the immune system's activity to prevent over-activation and tissue damage caused by inflammation. However, PD-1 is also expressed in tumor cells and functions as an immune evasion mechanism, making it a therapeutic target to enhance the immune response and eliminate tumor cells. Consequently, immune checkpoint inhibitors (ICIs) have emerged as an option for certain tumor types. Nevertheless, blocking immune checkpoints can lead to immune-related adverse events (irAEs), such as psoriasis and cytokine release syndrome (CRS), as exemplified in the clinical case presented by Zhou <i>et al</i> involving a patient with advanced gastric cancer who received sintilimab, a monoclonal antibody targeting PD-1. Subsequently, the patient experienced exacerbation of psoriasis and CRS. The objective of this editorial article is to elucidate potential immunologic mechanisms that may contribute to the development of CRS and psoriasis in patients receiving ICIs. It is crucial to acknowledge that while ICIs offer superior safety and efficacy compared to conventional therapies, they can also manifest irAEs affecting the skin, gastrointestinal tract, or respiratory system. In severe cases, these irAEs can lead to life-threatening complications such as circulatory shock or multiorgan failure. Consequently, it is recommended that patients receiving ICIs undergo regular monitoring to identify and manage these adverse events effectively.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 35","pages":"6782-6790"},"PeriodicalIF":1.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525914/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cat scratch disease in children with nocturnal fever: A case report.","authors":"Qi-Ling Yin, You-Qiong Liu, Hui-Min Zhang, Ya-Le Zhang, Shu-Min Qi, Jin-Quan Wen, Wei-Hua Zhang","doi":"10.12998/wjcc.v12.i35.6840","DOIUrl":"10.12998/wjcc.v12.i35.6840","url":null,"abstract":"<p><strong>Background: </strong>Cat scratch disease (CSD) is the most common human infection caused by <i>Bartonella henselae</i> (<i>B. henselae</i>). The main manifestation is self-limited lymphadenopathy that primarily affects adolescents, and typically resolves without treatment within 2-4 months. However, individuals with compromised immune systems or immunodeficiency require specific antibacterial therapy following diagnosis. Due to its low incidence, nonspecific clinical manifestations, and diagnostic limitations, this condition often poses challenges for clinicians in terms of missed diagnoses and misdiagnoses.</p><p><strong>Case summary: </strong>The child was ultimately diagnosed with CSD. The primary manifestations included nocturnal fever, enlargement of lymph nodes in the neck, axilla and groin, and suspected brucellosis; however, both brucellosis tests conducted during the course of the illness yielded negative results. Bone marrow cytology indicated stimulated proliferation. Lymph node biopsy indicated hyperplasia of lymphoid tissue in the cervical lymph nodes (right), with combined immunohistochemical findings indicating reactive hyperplasia. Immunohistochemical analysis revealed CD20 B (+), CD3 T (+), BCL-6 (+), and BCL-2 (-). CD21 FDC networks were present and Ki67 expression in the germinal center was ~80%. Blood next-generation sequencing indicated <i>B. henselae</i> sequence number was 3. Serological test results demonstrated positive antibody response to <i>B. henselae</i> IgG (+), <i>B. henselae</i> IgM (+), <i>Bartonella quintana</i> (<i>B. quintana</i>) IgG (-) and <i>B. quintana</i> IgM (-), and the final diagnosis was CSD.</p><p><strong>Conclusion: </strong>In patients presenting with fever at night and swollen lymph nodes of unknown origin, CSD should be considered.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 35","pages":"6840-6847"},"PeriodicalIF":1.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical landscape and treatment of acute non-variceal upper gastrointestinal bleeding: Insights from a high-volume center in Shaanxi, China.","authors":"Luca Improta","doi":"10.12998/wjcc.v12.i35.6855","DOIUrl":"10.12998/wjcc.v12.i35.6855","url":null,"abstract":"<p><p>In this editorial we comment on the article by Wang <i>et al</i>, recently published on <i>World Journal of Clinical Cases</i>. Acute non-variceal upper gastrointestinal bleeding (ANVUGIB) represents a common and potentially serious gastroenterological emergency. Wang <i>et al</i> conducted a detailed study on the management of ANVUGIB in a high-volume center in the Shaanxi region, China. Analyzing data from over 530 patients provided a comprehensive overview of clinical, epidemiological, and treatment characteristics. Results highlighted a younger patient population compared to European studies, with a higher prevalence of gastric and duodenal ulcers as the leading cause of bleeding. Endoscopic treatment is currently the preferred therapeutic option, offering a variety of effective techniques. This study emphasizes the importance of implementing current guidelines in ANVUGIB management and highlights the crucial role of endoscopy in its management.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 35","pages":"6855-6858"},"PeriodicalIF":1.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of atrial septal defects on the cardiac conduction system.","authors":"Jin-Hua Kang, Hong-Yan Wu, Wen-Jie Long","doi":"10.12998/wjcc.v12.i35.6770","DOIUrl":"10.12998/wjcc.v12.i35.6770","url":null,"abstract":"<p><p>The case report presented in this edition by Mu <i>et al</i>. The report presents a case of atrial septal defect (ASD) associated with electrocardiographic changes, noting that the crochetage sign resolved after Selective His Bundle Pacing (S-HBP) without requiring surgical closure. The mechanisms behind the appearance and resolution of the crochetage sign remain unclear. The authors observed the disappearance of the crochetage sign post-S-HBP, suggesting a possible correlation between these specific R waves and the cardiac conduction system. This editorial aims to explore various types of ASD and their relationship with the cardiac conduction system, highlighting the diagnostic significance of the crochetage sign in ASD.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 35","pages":"6770-6774"},"PeriodicalIF":1.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525910/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gut microbiota changes associated with frailty in older adults: A systematic review of observational studies.","authors":"Na-Na Wen, Li-Wei Sun, Qian Geng, Guo-Hua Zheng","doi":"10.12998/wjcc.v12.i35.6815","DOIUrl":"10.12998/wjcc.v12.i35.6815","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Frailty is a complex aging-related syndrome characterized by a cumulative loss of physiological reserve and increased vulnerability to adverse clinical outcomes, including falls, disability, incapacity and death. While an increasing number of studies suggest that the gut microbiota may play a key role in the pathophysiology of frailty, direct evaluation of the association between gut microbiome alterations and frailty in older adults remains limited.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To gain insight into gut dysbiosis in frail older adults.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Seven electronic databases (China National Knowledge Infrastructure, VIP, SinoMed, Wanfang, PubMed, Web of Science and EMBASE) were searched for articles published before October 31, 2023 to identify observational studies that compared the microbiomes of older adults with and without frailty. The diversity and composition of the gut microbiota were the main outcomes used to analyze the associations of changes in the gut microbiota with frailty in older adults. The quality of the included studies was assessed &lt;i&gt;via&lt;/i&gt; the Newcastle-Ottawa Scale and the Agency for Healthcare Research and Quality.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Eleven observational studies with 912 older adults were included in this review. Consistent results revealed a significant difference in the gut microbiota composition between frail and non-frail older adults, with a significant decrease in α diversity and a significant increase in β diversity in frail older adults. The pooled results revealed that at the phylum level, four microbiota (&lt;i&gt;Actinobacteria&lt;/i&gt;, &lt;i&gt;Proteobacteria&lt;/i&gt;, &lt;i&gt;Verrucomicrobia&lt;/i&gt; and &lt;i&gt;Synergistetes&lt;/i&gt;) were significantly enriched, and two microbiota (&lt;i&gt;Firmicutes&lt;/i&gt; and &lt;i&gt;Fusobacteria&lt;/i&gt;) were significantly depleted in frail older adults. At the family level, the results consistently revealed that the abundances of 6 families, most of which belong to the &lt;i&gt;Actinobacteria&lt;/i&gt; or &lt;i&gt;Proteobacteria&lt;/i&gt; phylum, were greater in frail than in non-frail older adults. At the genus or species level, consistent results from more than two studies revealed that the abundances of the genera &lt;i&gt;Prevotella&lt;/i&gt;, &lt;i&gt;Faecalibacterium,&lt;/i&gt; and &lt;i&gt;Roseburia&lt;/i&gt; were significantly lower in frail older adults; individual studies revealed that the abundances of some genera or species (&lt;i&gt;e.g.&lt;/i&gt;, &lt;i&gt;Megamonas&lt;/i&gt;, &lt;i&gt;Blautia&lt;/i&gt;, and &lt;i&gt;Megasphaera&lt;/i&gt;) were significantly lower, whereas those of other genera or species (&lt;i&gt;e.g.&lt;/i&gt;, &lt;i&gt;Bifidobacterium&lt;/i&gt;, &lt;i&gt;Oscillospira&lt;/i&gt;, &lt;i&gt;Ruminococcus&lt;/i&gt; and &lt;i&gt;Pyramidobacter&lt;/i&gt;) were significantly greater in frail older adults.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;This systematic review suggests that changes in the gut microbiota are associated with frailty in older adults, which is commonly reflected by a reduction in beneficial species and an increase in pathogenic species. However, further studies are needed to confirm these","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 35","pages":"6815-6825"},"PeriodicalIF":1.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of high-dose amoxicillin dual therapy for <i>Helicobacter pylori</i> eradication in an Irish cohort: A prospective study.","authors":"Raffaele Palmirotta, Concetta Cafiero, Marica Colella","doi":"10.12998/wjcc.v12.i35.6859","DOIUrl":"10.12998/wjcc.v12.i35.6859","url":null,"abstract":"<p><p><i>Helicobacter pylori</i> (<i>H. pylori</i>) infections may cause chronic gastritis, peptic ulcer disease, gastric cancers, and other conditions outside of the gastrointestinal tract. Hence, it is important to diagnose and treat it early. <i>H. pylori</i> is resistant to certain drugs in traditional eradication therapy, so alternative therapy protocols are needed, such as high-dose amoxicillin dual therapy (HDADT). This article aims to comment on a recent paper by Costigan <i>et al</i> in the <i>World Journal of Clinical Cases</i>. In this study, the authors recruited 139 patients diagnosed with <i>H. pylori</i>, all treated with HDADT. Of these, 93 were treatment-naïve and 46 had received at least one alternative treatment in the past. Four weeks after the end of the treatment, the urea breath test was administered to estimate the eradication rate. The total eradication rate was 56% (78/139), 62% for the treatment-naïve arm and 43% for the previous treatment arm, thus indicating a lower success rate for the arm that had previously received a different treatment regimen. In conclusion, a therapeutic approach with first-line HDADT may potentially be a better treatment, but the results are not sufficient to recommend the use of this regimen in a country with high levels of dual resistance.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 35","pages":"6859-6863"},"PeriodicalIF":1.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing oral cancer care: Insights from Tongluo Jiedu prescription.","authors":"Chun-Yao Cheng, Wen-Rui Hao, Ju-Chi Liu, Tzu-Hurng Cheng","doi":"10.12998/wjcc.v12.i35.6764","DOIUrl":"10.12998/wjcc.v12.i35.6764","url":null,"abstract":"<p><p>This editorial highlights the study which investigated the potential of traditional Chinese medicine (TCM) as an adjunctive therapy in oral cancer management. The study included 80 patients with oral cancer to evaluate the effects of the Tongluo Jiedu prescription on inflammatory stress markers, peripheral blood T-cell subsets, and overall immune function. The results indicated that Tongluo Jiedu substantially enhances immune function and reduces oxidative stress, thereby aiding in patient recovery and potentially minimizing treatment-related complications. This editorial discusses the broader implications of these findings for oral cancer care and emphasizes the importance of integrating TCM principles into modern oncology practices.</p>","PeriodicalId":23912,"journal":{"name":"World Journal of Clinical Cases","volume":"12 35","pages":"6764-6769"},"PeriodicalIF":1.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11525912/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}