Hanah H Karadachi, Alejandro N Santos, Laurèl Rauschenbach, Enrique González-Gallardo, Anna Michel, Marvin Darkwah Oppong, Thomas Wälchli, Yan Li, Cornelius Deuschl, Ramazan Jabbarli, Yahya Ahmadipour, Karsten H Wrede, Ulrich Sure, Philipp Dammann
{"title":"Cerebral Cavernous Malformation: The impact of associated Developmental Venous Anomaly on surgical treatment outcome.","authors":"Hanah H Karadachi, Alejandro N Santos, Laurèl Rauschenbach, Enrique González-Gallardo, Anna Michel, Marvin Darkwah Oppong, Thomas Wälchli, Yan Li, Cornelius Deuschl, Ramazan Jabbarli, Yahya Ahmadipour, Karsten H Wrede, Ulrich Sure, Philipp Dammann","doi":"10.1016/j.wneu.2025.124219","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124219","url":null,"abstract":"<p><strong>Background: </strong>Goal of this study was to analyze retrospectively the course of patients with cerebral cavernous malformation (CCM) and associated developmental venous anomaly (DVA) concerning neurological outcome and formation of CCM recurrence or de-novo-formation after surgical removal of the lesion.</p><p><strong>Methods: </strong>1469 patients diagnosed with CCM were referred to our institution from 2003 to 2022. Adult patients with sporadic CCM, complete magnetic resonance imaging dataset, and ≥ 2 follow-up investigations after surgical resection were analyzed. Patient's clinical data, surgical and radiological reports were retrospectively assessed. Multiple factors regarding functional outcome were scanned using logistic regression analyses with p < 0.05. Preoperative and postoperative neurological function was assessed using modified Rankin Scale (mRS).</p><p><strong>Results: </strong>183 patients were included in this study; 59 of 183 presented associated DVA. Mean preoperative mRS in the CCM + DVA group was 1.7 (± 0.9), in the CCM - DVA group 1.97 (± 0.8), while mean mRS at last follow-up was 0.65 (± 0.89) in the CCM + DVA, and 0.93 (± 0.92) in the CCM - DVA group. Recurrence of CCM lesion was seen in 1 case in the CCM + DVA group and in 2 cases in the CCM - DVA group. Significant differences in the neurological status preoperatively (p = 0.046) and at last follow-up (p = 0.049) could be detected for the benefit of the CCM + DVA group.</p><p><strong>Conclusions: </strong>DVA does not represent an additional risk for neurological deterioration in the surgical resection of CCM. Postoperative CCM recurrence is negligible.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124219"},"PeriodicalIF":1.9,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shenyan Gu, Kaiwen Chen, Dongqing Zhu, Feizhou Lyu, Jianyuan Jiang, Joe F Jabre, Xinlei Xia, Chaojun Zheng
{"title":"Determining the reference values of the measurements of cervical sagittal alignment using the e-norms method.","authors":"Shenyan Gu, Kaiwen Chen, Dongqing Zhu, Feizhou Lyu, Jianyuan Jiang, Joe F Jabre, Xinlei Xia, Chaojun Zheng","doi":"10.1016/j.wneu.2025.124227","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124227","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the feasibility of the e-norms method for establishing a reference range for the measurements of cervical sagittal alignment and to explore the differences in these ranges according to sex and age.</p><p><strong>Methods: </strong>We applied the e-norms method to calculate reference values for the angle between occipital and C2 vertebrae (O-C2 angle), C2-7 Cobb angle, C2-7 sagittal vertical axis (SVA) and C7 slope in 1720 subjects. The e-norms values of these measurements were measured in different age subgroups of male or female subjects.</p><p><strong>Results: </strong>According to the data points within the plateau obtained via e-norms method, normal O-C2 angle was 18.5±2.6°, C2-7 Cobb angle was 8.8±4.5°, C2-7 SVA was 1.5±0.4 cm, and C7 slope was 20.1±3.5°. These data points involved a total of 1617 (1617/1720, 94.0%) subjects, with only 191 (11.1%, 191/1720) subjects having all the cervical sagittal measurements included in the plateau. Both C2-7 Cobb angle and C7 slope e-norms values increase with age in females, whereas only C7 slope e-norms values increase with age in males. The males showed greater e-norms values in at least one of cervical sagittal measurements compared with females in different age subgroups (P<0.05).</p><p><strong>Conclusion: </strong>This study demonstrated that e-norms may be a simple, reliable and cost-saving approach for establishing reference values for cervical sagittal measurements. This new method allows us to establish reference values for sex or age subgroups to study the sex differences and trends with age of cervical sagittal alignment.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124227"},"PeriodicalIF":1.9,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In Reply to the Letter to the Editor Regarding: Evaluation of the Therapeutic Effect of Decompression with or without Fusion on Lumbar Spinal Stenosis Caused by Degenerative Lumbar Spondylolisthesis: A Systematic Review and Meta-Analysis.","authors":"Jie Guo, Tianwei Sun","doi":"10.1016/j.wneu.2025.124225","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124225","url":null,"abstract":"","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124225"},"PeriodicalIF":1.9,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor Regarding: Surgical Delay and Functional Outcome After Surgery for Chronic Subdural Hematoma.","authors":"Areeba Abid, Aliza Azmat, Ayesha Qayyum","doi":"10.1016/j.wneu.2025.124215","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124215","url":null,"abstract":"","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124215"},"PeriodicalIF":1.9,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The \"One Coin Bypass\" Technique as a Minimally Invasive Navigation-Guided Superficial Temporal Artery to Middle Cerebral Artery Bypass.","authors":"Hiromasa Kobayashi, Takashi Morishita, Shintarou Yoshinaga, Dai Kawano, Toshiyuki Enomoto, Koichiro Takemoto, Tooru Inoue, Hiroshi Abe","doi":"10.1016/j.wneu.2025.124211","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124211","url":null,"abstract":"<p><strong>Background and objectives: </strong>Minimally invasive cerebral revascularization techniques are increasingly sought to reduce surgical trauma while preserving efficacy. The \"One Coin bypass\" is a navigation-guided superficial temporal artery to middle cerebral artery (STA-MCA) bypass performed through a coin-sized craniectomy and 3.0 cm skin incision. This study aimed to evaluate its clinical feasibility and surgical benefits.</p><p><strong>Methods: </strong>We retrospectively analyzed 29 patients who underwent single-vessel STA-MCA bypass for symptomatic internal carotid or middle cerebral artery stenosis or occlusion between 2017 and 2022. The One Coin bypass was introduced in January 2021; earlier cases served as a historical control group. Surgical parameters and clinical outcomes were compared between the One Coin group (n=10) and the conventional bypass group (n=19).</p><p><strong>Results: </strong>The One Coin group had significantly shorter skin incisions (3.0 cm vs. 8.0 ± 2.3 cm, p < 0.05), smaller craniectomy diameter (17 mm vs. 45 ± 5.7 mm, p < 0.05), and reduced total operative time (136 ± 13.1 min vs. 219 ± 31.1 min, p < 0.05). Anastomosis times were comparable (p = 0.837). No major complications occurred in the One Coin group, while one infarction was noted in the conventional group. All bypasses remained patent.</p><p><strong>Conclusion: </strong>The One Coin bypass was shown to be a safe and effective minimally invasive alternative to conventional STA-MCA bypass, offering reduced surgical exposure without compromising bypass quality. It may be especially advantageous in elderly or high-risk patients.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124211"},"PeriodicalIF":1.9,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Iris S C Verploegh, James Rutka, Torstein R Meling, Victor Volovici
{"title":"Safe and effective: words carry power and responsibility.","authors":"Iris S C Verploegh, James Rutka, Torstein R Meling, Victor Volovici","doi":"10.1016/j.wneu.2025.124224","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124224","url":null,"abstract":"","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124224"},"PeriodicalIF":1.9,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcos Ezequiel Yasuda, Mohd Afiq Mohd Slim, Yousif Alammar, Doron D Sommer, Matteo de Notaris, Kesava Reddy
{"title":"Novel Vascularized Pedicle Flaps for Dural Reconstruction via Endoscopic Transorbital Approach: Temporalis Muscle and Pericranial Flaps.","authors":"Marcos Ezequiel Yasuda, Mohd Afiq Mohd Slim, Yousif Alammar, Doron D Sommer, Matteo de Notaris, Kesava Reddy","doi":"10.1016/j.wneu.2025.124217","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124217","url":null,"abstract":"","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124217"},"PeriodicalIF":1.9,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor 'Evaluation of the Therapeutic Effect of Decompression with or without Fusion on Lumbar Spinal Stenosis Caused by Degenerative Lumbar Spondylolisthesis: A Systematic Review and Meta-Analysis'.","authors":"Linxing Zhong, Liangfeng Wei","doi":"10.1016/j.wneu.2025.124214","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124214","url":null,"abstract":"","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124214"},"PeriodicalIF":1.9,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor Regarding: Surgical Strategies in Basal Ganglia Gliomas: A Systematic Review of Resection Extent, Mortality, and Neurological Recovery.","authors":"Shamsudheen Cholayil, Vangipuram Harshil Sai, Vangipuram Shankar","doi":"10.1016/j.wneu.2025.124212","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124212","url":null,"abstract":"","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124212"},"PeriodicalIF":1.9,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144529908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brian J Conway, Stephanie A Armstrong, Nada Botros, Sergey Tarima, Max O Krucoff
{"title":"Predictors of Permanent and Temporary Motor Deficits in Patients Undergoing Glioma Resection: A Systematic Review and Meta-Analysis.","authors":"Brian J Conway, Stephanie A Armstrong, Nada Botros, Sergey Tarima, Max O Krucoff","doi":"10.1016/j.wneu.2025.124200","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124200","url":null,"abstract":"<p><strong>Purpose: </strong>To identify predictors of permanent and temporary motor deficits in patients undergoing glioma resection.</p><p><strong>Methods: </strong>A literature search accessed the databases Ovid Medline, Scopus, Web of Science, CINAHL/EBSCO, PsychInfo, Cochrane and Wiley for studies reporting motor outcomes following surgical resection of glioma. Outcomes were stratified by patient/tumor characteristics, pre-operative condition, and intra-operative factors for both permanent and temporary motor deficits. Generalized estimating equations were used to generate odds ratios.</p><p><strong>Results: </strong>A total of 1,332 titles and abstracts were reviewed resulting in the evaluation of 261 full-text articles. Data were extracted from 67 studies including 2,616 patients with 371 (14%) developing permanent postoperative motor deficits, 465 (18%) developing temporary deficits, and the remaining 1,780 (68%) having no deficit. Pre-operative deficit was the most significant predictor of permanent post-operative motor deficit (OR6.40, CI2.82-14.5, p<0.0001), while high pre-operative Karnofsky Performance Scale (KPS) (OR0.98, CI 0.97-0.99, p<0.001) and subcortical tumor location (OR0.14, C 0.030-0.62, p=0.001) had a lower odds of a permanent deficit. Intra-operative MEP changes was a significant predictor of both permanent (OR5.18, CI1.99-13.5, p=0.00075) and temporary (OR9.44, CI2.78-32.0, p=0.0003) motor deficits.</p><p><strong>Conclusions: </strong>Pre-operative motor deficits were the most significant predictors of persistent or worsening postoperative motor deficits. Intra-operative MEP changes were associated with both permanent and temporary deficits. High KPS and subcortical tumor location and a lower odds of permanent motor deficits.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124200"},"PeriodicalIF":1.9,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144512580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}