World neurosurgery最新文献

{"title":"Intraoperative ICG-VA with FLOW800 and multimodal fusion neuro-navigation for the resection of arteriovenous malformation with reduced blood loss.","authors":"Xingyu Yang, Xinyu Tao, Jiahao Meng, Wanchun You, Feng Gu, Jiaxuan Li, Zhichao Tian, Zhong Wang","doi":"10.1016/j.wneu.2025.124193","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124193","url":null,"abstract":"<p><strong>Objective: </strong>To assess the safety and effectiveness of combining indocyanine green videoangiography (ICG-VA) with FLOW800 and multimodal fusion neuro-navigation in brain arteriovenous malformation microsurgical resection.</p><p><strong>Methods: </strong>From January 1, 2019, to December 31, 2022, 90 consecutive patients at The First Affiliated Hospital of Soochow University diagnosed with AVMs were included. Patients were divided into a combined treatment group and a non-combined treatment group based on the treatment received. Clinical data including baseline characteristics, image findings, mRS, pre- and postoperation hemoglobin/ hematocrit levels were reviewed and collected for statistical analysis.</p><p><strong>Results: </strong>Compared with the non-combined treatment group, the combined treatment group demonstrated a smaller postoperative decline in hemoglobin and hematocrit levels after operation, as well as a higher proportion of patients with no disability at discharge and at the six-month follow-up. Additionally, the combined treatment group had lower rates of reoperation and post-operative complications. Compared with the non-combined-treatment group, the combined-treatment group demonstrated a smaller postoperative decline in hemoglobin and hematocrit levels, as well as a higher proportion of patients with no disability at discharge and at the six-month follow-up. Additionally, the combined-treatment group had lower rates of reoperation and postoperative complications.</p><p><strong>Conclusions: </strong>The combined utilization of intraoperative ICG-VA with FLOW800 and multimodal fusion neuro-navigation appears to reduce intraoperative blood loss and enhance functional outcomes in AVM microsurgery, thereby improving both the safety and efficacy of the procedure.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124193"},"PeriodicalIF":1.9,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor Regarding \"Analysis of Risk Factors for Lumbar Spondylolisthesis: A Logistic Regression Study\".","authors":"Jiange Chen, Aifeng Liu","doi":"10.1016/j.wneu.2025.124194","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124194","url":null,"abstract":"","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124194"},"PeriodicalIF":1.9,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144337122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A pre-warning signalling in Motor Evoked Potentials Monitoring for Insular Glioma surgery. A preliminary study.","authors":"Camilla Bonaudo, Sara Lombardi, Giulia Sorbi, Eleonora Visocchi, Manuel Camelia, Anastasia Galletti, Alice Esposito, Agnese Pedone, Fabrizio Baldanzi, Simone Troiano, Cristiana Martinelli, Riccardo Carrai, Francesca Battista, Giovanni Muscas, Simone Orlandini, Luca Campagnaro, Andrea Boschi, Serena Tola, Antonello Grippo, Leonardo Bocchi, Alessandro Della Puppa","doi":"10.1016/j.wneu.2025.124185","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124185","url":null,"abstract":"<p><strong>Objective: </strong>Insular gliomas are surgically challenging. Intraoperative neurophysiological monitoring assists surgical excision. Although still controversial, a reduction of Motor Evoked Potential (MEPs) signal>50% correlates with postoperative impairment. However, this reduction often occurs too late. Identifying pre-warning indicators, anticipating MEPs drop>50%, could optimise surgery of insular gliomas.</p><p><strong>Methods: </strong>Monocentric retrospective study, collecting clinical, surgical and neurophysiological data of patients harbouring insular intra-axial lesions. I) MEPs tracking included the baseline, compared with all subsequently recorded signals. Upper limb muscles were analysed. II) The Fourier transform was used to modulate the recorded signals. III) The Dynamic Time Warping (DWT) was then applied followed by Logistic Regression.</p><p><strong>Results: </strong>Out of 300 patients operated on for supratentorial lesions (January 2023-September 2024), 30 patients with insular tumours were finally enrolled. The efficacy of the logistic regression model resulted in high accuracy [91.45%]: it allowed us to identify a pre-warning signal (PWS), anticipating the decrease in MEPs>50% (i.e. Warning Sign=WS), by considering new parameters of DTW. Comparing MEPs tracks and the identified parameters, our results revealed that PWS compared to WS has the same Se[83.3%]and NPV [93.8%] in identifying MEPs drop and correlating with the postoperative clinical outcome. Compared to WS, PWS has superimposable Sp and PPV correlating with prediction of motor deficits (Sp:62.5%, PPV: 35.7%). Therefore, PWS may be more reliable than WS to interpret IOM variations and predict the clinical outcome.</p><p><strong>Conclusions: </strong>Based on our preliminary data, PWS is reliably predictive of motor outcome, and more accurate than WS to identify IOM variations.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124185"},"PeriodicalIF":1.9,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lateral Ponticle Prevalence in 754 Atlas Vertebrae: A South African Skeletal Population.","authors":"Ashley J Woolley, Glen J Paton","doi":"10.1016/j.wneu.2025.124187","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124187","url":null,"abstract":"","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124187"},"PeriodicalIF":1.9,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced Visualization, Reduced Burden: Endoscopic vs. Tubular Spine Surgery for Lumbar Stenosis.","authors":"Schahin Salmanian, Samantha Schimmel, Bryan Clampitt, Maya Toothman, Petra Allen, Chloe Chose, Cesar Carballo, Diego Soto-Rubio, Jay Kumar, Puya Alikhani, Patrick Kim","doi":"10.1016/j.wneu.2025.124186","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124186","url":null,"abstract":"<p><strong>Background: </strong>Spinal stenosis is a common degenerative condition affecting quality of life. Minimally invasive surgical (MIS) techniques like tubular and endoscopic decompression are increasingly favored over open surgery, but direct comparisons remain limited. This study evaluates their relative effectiveness in terms of operative metrics, postoperative pain, complications, and hospital stay.</p><p><strong>Methods: </strong>We conducted a retrospective single-center review of 180 patients who underwent tubular (n = 101) or endoscopic (n = 79) MIS decompression for lumbar spinal stenosis between June 2021 and April 2024. Demographics, perioperative variables, and outcomes such as pain scores, infection rates, reoperations, and hospital stay were compared using standard statistical tests.</p><p><strong>Results: </strong>Both groups had similar complication and reoperation rates. Endoscopic patients reported significantly lower immediate postoperative pain (p = 0.001) and greater pain reduction from baseline (p = 0.020). No infections occurred in the endoscopic group, compared to a 5.0% infection rate in the tubular group (p = 0.045). Endoscopic cases also showed shorter in-room to incision times (p = 0.045) and reduced closure durations (p < 0.001). Hospital stay length was comparable (p = 0.138), though complications prolonged stays in the tubular group.</p><p><strong>Conclusions: </strong>Both techniques are effective for MIS spinal decompression. Endoscopic surgery offers advantages in short-term outcomes, including lower infection risk, improved pain relief, and greater procedural efficiency. These findings support its growing role, though further prospective studies are warranted to refine clinical recommendations.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124186"},"PeriodicalIF":1.9,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trigeminal Schwannoma Resection: A Systematic Review Functional Outcomes with Endoscopic and Microscopic Approaches.","authors":"Bahaeddin A Muhsen","doi":"10.1016/j.wneu.2025.124162","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124162","url":null,"abstract":"<p><strong>Background and objectives: </strong>Trigeminal schwannoma are rare benign tumors arising from the trigeminal nerve, often requiring surgical intervention for symptom relief and functional preservation. This systematic review compares functional outcomes and complication rates between endoscopic and microscopic resection approaches.</p><p><strong>Methods: </strong>A comprehensive search was conducted using PubMed, Embase, Cochrane Library, and Scopus to identify studies meeting inclusion criteria. Data on patient demographics, tumor characteristics, surgical outcomes, and postoperative complications were extracted and analyzed.</p><p><strong>Results: </strong>Results indicate varying functional outcomes with each approach, highlighting differences in sensory deficits, cranial nerve function preservation, and recurrence rates.</p><p><strong>Conclusion: </strong>These findings provide valuable insights for neurosurgeons in selecting optimal surgical strategies for trigeminal schwannoma management.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124162"},"PeriodicalIF":1.9,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative non-infectious fever in degenerative lumbar spine diseases: A Multivariate Logistic Regression Analysis.","authors":"Yao Li, Guanyu Yang, Tianci Fang, Fanqi Kong, Peng Yang, Bin Pi, Huilin Yang, Xuwei Ling","doi":"10.1016/j.wneu.2025.124190","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124190","url":null,"abstract":"<p><strong>Objective: </strong>Postoperative fever frequently occurs following lumbar surgery. However, limited studies have examined its correlation with lumbar procedures. This study aims to assess the occurrence of postoperative fever and identify its potential risk factors after lumbar surgery.</p><p><strong>Methods: </strong>A retrospective study was conducted on 330 patients who underwent lumbar surgery from January 2023 to November 2024. Postoperative fever was defined as a body temperature of ≥37.8°C. Based on the highest recorded temperature, patients were categorized into two groups. Statistical analyses included the independent sample t-test and Chi-square test, while multivariate logistic regression analysis was applied to determine independent risk factors for postoperative fever.</p><p><strong>Results: </strong>Thirty-nine patients experienced at least one postoperative fever during their hospital stay, which accounted for 11.82% of the total patient population. The peak incidence of postoperative fever occurred on the fifth day, with 33.33% of patients experiencing their first fever on this day. Furthermore, 69.23% of patients had a moderate fever, characterized by a body temperature ranging from 38 to 39°C. Multivariate logistic regression indicated that obesity, the mode of operation (fusion surgery), longer duration of surgery, and prolonged postoperative retention of the drainage tube were independently associated with an increased risk of fever.</p><p><strong>Conclusion: </strong>The findings of this study suggest that postoperative fever is a frequent occurrence following lumbar surgery. Factors such as surgery procedures (e.g., fusion), obesity, extended surgical duration, and prolonged retention of the drainage tube may elevate the risk of developing postoperative fever.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124190"},"PeriodicalIF":1.9,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poor Correlation Between Inflammatory and Brain Injury Biomarkers After Neonatal Intraventricular Hemorrhage: A Pilot Study.","authors":"Ankit Agarwal, Miriam Zamorano, Aidan Collier, Braden Oldham, Kaleigh Riggs-Harpur, Thao L Nguyen, David I Sandberg, Stephen A Fletcher, Manish N Shah, Brandon A Miller","doi":"10.1016/j.wneu.2025.124177","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124177","url":null,"abstract":"<p><strong>Background: </strong>This study investigated changes in hemoglobin, neuroinflammatory and brain injury biomarkers (Tumor necrosis factor-alpha (TNF-α) and glial fibrillary acidic protein (GFAP)) in early stages of cerebrospinal fluid (CSF) diversion in preterm neonates with intraventricular hemorrhage (IVH). We hypothesized that patients with higher CSF hemoglobin levels would have higher TNF-α and GFAP levels.</p><p><strong>Methods: </strong>This prospective study included infants with grade 3 or 4 IVH. All had ventricular reservoirs were placed following standard neurosurgical care. The first CSF sample was collected day of reservoir placement. Subsequent samples were from clinically indicated CSF withdraws to decompress ventricles. Enzyme-linked Immunosorbent Assays were performed using commercially available kits and standard methods.</p><p><strong>Results: </strong>Eight preterm infants were included in the study. Median post-menstrual age was 26.3 weeks, and median birth weight was 765 grams. No biomarkers investigated had a significant correlation with days since reservoir placement. Initially, GFAP and hemoglobin were significantly correlated (Pearson's r = -0.682, p<0.001), so a linear regression was conducted (slope = -0.00363). However, this relationship was lost when the power of repeated measures analysis was leveraged (repeated measures correlation r = -0.473, p=0.055, Bonferroni adjusted alpha level =0.008).</p><p><strong>Conclusions: </strong>This study found no significant correlation between CSF hemoglobin, TNF-α, and GFAP in the first weeks of CSF diversion in neonates with IVH. There is high variability of these measures, even within subjects. This study reveals the need for further research into neuroinflammatory and brain injury biomarkers in neonates with IVH, their usefulness in clinical decision making, and long-term outcomes.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124177"},"PeriodicalIF":1.9,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor Regarding: Efficacy and Safety of Initiating Intravenous Glycoprotein IIb/IIIa Inhibitors Before Acute Stent Implantation in Patients with Cerebral Infarction: A Systematic Review and Meta-Analysis.","authors":"Digvijay Singh Rajawat, Saketh Sainag Mandiga, Keerthi Sanapala","doi":"10.1016/j.wneu.2025.124179","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124179","url":null,"abstract":"","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124179"},"PeriodicalIF":1.9,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor Regarding: Incidence and risk factors of delayed facial paralysis after vestibular schwannoma resection: A systematic review and meta-analysis.","authors":"Digvijay Singh Rajawat, Saketh Sainag Mandiga, Keerthi Sanapala","doi":"10.1016/j.wneu.2025.124175","DOIUrl":"https://doi.org/10.1016/j.wneu.2025.124175","url":null,"abstract":"","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"124175"},"PeriodicalIF":1.9,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}