Davi Amorim Meira , Silvio Porto Júnior , Beatriz Lopes Bernardo da Cunha , Jefferson Heber Marques Fontes , Hugo Nunes Pustilnik , Matheus Gomes da Silva da Paz , Tancredo Alcântara , Leonardo Miranda de Avellar
{"title":"In Reply to the Letter to the Editor Regarding “Simultaneous Single-Trajectory Endoscopic Biopsy and Third Ventriculostomy in Pineal Region Tumors: A Systematic Review and Single Arm Meta-Analysis”","authors":"Davi Amorim Meira , Silvio Porto Júnior , Beatriz Lopes Bernardo da Cunha , Jefferson Heber Marques Fontes , Hugo Nunes Pustilnik , Matheus Gomes da Silva da Paz , Tancredo Alcântara , Leonardo Miranda de Avellar","doi":"10.1016/j.wneu.2024.11.014","DOIUrl":"10.1016/j.wneu.2024.11.014","url":null,"abstract":"","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":"194 ","pages":"Article 123431"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarazhyna Kateryna, Solodovnikova Yulia, Son Anatoliy
{"title":"Letter to the Editor Regarding Abnormal Rhomboid Lip and Choroid Plexus Should be Valued in Microvascular Decompression for Vestibulocochlear Diseases","authors":"Sarazhyna Kateryna, Solodovnikova Yulia, Son Anatoliy","doi":"10.1016/j.wneu.2024.12.016","DOIUrl":"10.1016/j.wneu.2024.12.016","url":null,"abstract":"","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":"194 ","pages":"Article 123557"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical Strategy and Decision-Making in Recurrent Atlanto-Axial Dislocations: The Role of Traction","authors":"Kavin K. Devani , Souvik Singha , Pulkit Purohit , Nupur Pruthi","doi":"10.1016/j.wneu.2024.10.099","DOIUrl":"10.1016/j.wneu.2024.10.099","url":null,"abstract":"<div><h3>Objective</h3><div>To analyse patients with recurrent atlanto-axial dislocation and give a criterion of an ideal patient who can benefit from redo surgery.</div></div><div><h3>Methods</h3><div>This retrospective study was conducted in a tertiary care center, which included 20 patients who failed atlanto-axial surgery from January 2013 to June December 2021. They were evaluated using X-ray, computed tomography, and magnetic resonance imaging examinations, and their clinical data were accessed from the hospital’s medical records department and the picture archiving and communication system. They were given a trial of traction to look for clinical and/or radiological improvement. Those showing clinical and/or radiological improvement underwent redo fixation. The operative steps involved removing joint capsules, denuding articular cartilage and joint preparation followed by reduction of basilar invagination by the combination of spacer and/or bone graft and putting screws in C1/Occiput and C2. A strut graft was placed between Occiput/C1 and C2.</div></div><div><h3>Results</h3><div>The mean change in modified Japanese Orthopaedic Association Scores and Nurick grade following the first surgery was statistically significant (1.00 ± 0.73, <em>P</em> value 0.002 and −0.15 ± 0.27, <em>P</em> value 0.046, respectively). On similar paths, the mean change in modified Japanese Orthopaedic Association Scores and Nurick grade following the second surgery was also statistically significant (4.25 ± 0.32, <em>P</em> value < 0.001 and −1.2 ± 0.11, <em>P</em> value < 0.001, respectively). Improper usage of constructs (31.57%), inadequate/no joint preparation (42.10%/57.90%), and poor choice of graft (100%) were the leading causes of failure of index surgery.</div></div><div><h3>Conclusions</h3><div>The best candidates who can benefit after redo surgery are the ones who exhibit either clinical and/or radiological improvement on the trial of traction, as the pathological C1-C2 joints are either not fused or have undergone pseudoarthrosis. Those patients who do not exhibit significant clinical or radiological improvement post-trial of traction should not be offered subsequent surgical intervention.</div></div>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":"194 ","pages":"Article 123370"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dylan Chiche , Luc Taillandier , Marie Blonski , Sophie Planel , Tiphaine Obara , René Anxionnat , Fabien Rech
{"title":"DTI Analysis of the Peritumoral Zone of Diffuse Low-grade Gliomas in Progressing Patients","authors":"Dylan Chiche , Luc Taillandier , Marie Blonski , Sophie Planel , Tiphaine Obara , René Anxionnat , Fabien Rech","doi":"10.1016/j.wneu.2024.10.111","DOIUrl":"10.1016/j.wneu.2024.10.111","url":null,"abstract":"<div><h3>Background</h3><div>Diffuse low-grade gliomas are rare brain tumors transforming to higher grade even with surgery, chemotherapy, and radiotherapy. Their preferential infiltration of white matter tracts, beyond tumor boundaries on fluid-attenuated inversion recovery (FLAIR), make difficult to plan focal treatment such as surgery or radiotherapy and monitor response to chemotherapy. Diffusion tensor imaging (DTI) might reflect this infiltration of white matter tracts. The aim of our study is to assess how DTI signal in the peritumoral zone might be modified before FLAIR tumor progression appears at 1-year follow-up.</div></div><div><h3>Methods</h3><div>The study retrospectively enrolled 5 patients who met inclusion criteria: DTI with 25 directions, T1 and FLAIR at initial imaging; FLAIR at one-year follow-up. Patients with surgery, radiotherapy, and chemotherapy completed less than 2 years before initial imaging were excluded. FLAIR tumor progression, named progression mask, was assessed by subtracting tumor masks between initial imaging and one-year follow-up. Initial DTI signal was analyzed within this progression mask and compared with the healthy contralateral side.</div></div><div><h3>Results</h3><div>Tumor progression was confirmed for the 5 patients at 1 year. All patients showed pre-existing DTI signal abnormalities within the progression mask. Mean fractional anisotropy (<em>P</em> = 0.03) was lower in the progression mask, whereas mean diffusivity, axial diffusivity, and radial diffusivity mean (<em>P</em> = 0.03) was higher in the progression mask, compared with the healthy side.</div></div><div><h3>Conclusions</h3><div>This study shows pre-existing DTI signal abnormalities in regions with tumor progression at 1 year. Such abnormalities could correspond to a tumor infiltration not yet visible on FLAIR. This might be helpful to predict tumor progression and allow to adapt the therapeutic strategy.</div></div>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":"194 ","pages":"Article 123382"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improvement of Neurogenic Bladder Dysfunction Following Combined Cell Therapy with Mesenchymal Stem Cell and Schwann Cell in Spinal Cord Injury: A Randomized, Open-Label, Phase II Clinical Trial","authors":"Mohammadhosein Akhlaghpasand , Roozbeh Tavanaei , Farzad Allameh , Maede Hosseinpoor , Hossein Toreyhi , Maryam Golmohammadi , Atieh Hajarizadeh , Alireza Alikhani , Maryam Hafizi , Maryam Oraee-Yazdani , Alireza Zali , Saeed Oraee-Yazdani","doi":"10.1016/j.wneu.2024.10.131","DOIUrl":"10.1016/j.wneu.2024.10.131","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the efficacy of intrathecal combined administration of autologous bone marrow-derived mesenchymal stem cells (BMSCs) and Schwann cells (SCs) in urinary function improvement in complete spinal cord injury (SCI) patients for the first time.</div></div><div><h3>Methods</h3><div>This study was a randomized phase II clinical trial, including treatment and control arms. Patients with traumatic complete SCI-induced neurogenic bladder were included. The treatment group received a single intrathecal combined injection of autologous BMSCs and SCs. The control group underwent no additional intervention. The outcome measures of the study were urodynamic study parameters, number of incontinence and urinary tract infection episodes, incontinence quality of life questionnaire, functional status, and sensorimotor improvements.</div></div><div><h3>Results</h3><div>Among a total of 32 recruited patients, 13 and 16 were completely followed up in the treatment and control group, respectively. Changes in bladder compliance (<em>P</em> = 0.032), maximum pressure of detrusor during the filling phase (P = 0.013), maximum pressure of detrusor at the maximum urinary flow rate (<em>P</em> = 0.020), maximum urinary flow rate (<em>P</em> = 0.001), and postvoid residual volume (<em>P</em> = 0.001) after 6 months were significantly different between the 2 groups. The number of urinary incontinence episodes (<em>P</em> = 0.022) significantly reduced in the treatment group after 6 months compared with the baseline. The incontinence quality of life total and domain scores significantly improved in the treatment group compared with the control group after 6 months.</div></div><div><h3>Conclusions</h3><div>The combined intrathecal administration of BMSCs and SCs significantly improved the urodynamic study parameters, urinary incontinence rate, and incontinence quality of life in complete SCI-induced neurogenic bladder.</div></div>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":"194 ","pages":"Article 123402"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Systematic Analysis for the Reason of Revision-Surgery After Non-Total En Bloc Spondylectomy Open Surgery Among Spinal Metastatic Tumor Cases: A Retrospective Study","authors":"Qi Feng, Kai-Bo Zhang, Xu-Jian Liu, Jian-Gang Feng, Xiao-Yu Zhang, Jian-Fa Xu, Jing Shan, Dong-Lai Wang","doi":"10.1016/j.wneu.2024.10.144","DOIUrl":"10.1016/j.wneu.2024.10.144","url":null,"abstract":"<div><h3>Objective</h3><div>This study examines patients with metastatic spinal disease undergoing non-total en bloc spondylectomy, focusing on revision surgery reasons and its effectiveness in treating spinal instability, neurological issues, and pain.</div></div><div><h3>Methods</h3><div>This study conducted a retrospective case series in a single center and included 344 patients with metastatic spinal tumor who underwent non-total en bloc spondylectomy open surgery between 2013 and 2021 and were followed up for >2 years.</div></div><div><h3>Results</h3><div>Of 344 patients, 20 (7.1%) had revision surgery due to delayed infection (n = 1), fixation loosening (n = 2), and tumor recurrence (n = 17). The revision group had lower rates of radiotherapy (35%) and long-segment fixation (45%) than the unrevised group (60.2%, 74%; <em>P</em> < 0.001). Decompression surgery had the highest revision rate (15.8%), followed by vertebrectomy (8.9%), separation surgery (4.7%), and hybrid surgery (2.3%). Postoperative scores and survival rates were improved in the revision group (median survival 32 vs. 11 months; <em>P</em> < 0.05).</div></div><div><h3>Conclusions</h3><div>Long-segment fixation with radiotherapy may reduce revision surgery need and extend the time between surgeries. Hybrid or separation surgeries lower the likelihood of revision. Revision surgery can relieve pain and improve neurological function. Patients in the revision group have longer survival times.</div></div>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":"194 ","pages":"Article 123415"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yunmou Ou , Chaofeng Liang , Qilong Chen , Jin Gong , Manting Li , Miao Tang , Dengjun Wu , Cheng Ding , Ying Guo
{"title":"Approaches for the Minimally Invasive Resection of Chiasmatic Cavernous Hemangioma: Analysis of 56 Cases in the Literature","authors":"Yunmou Ou , Chaofeng Liang , Qilong Chen , Jin Gong , Manting Li , Miao Tang , Dengjun Wu , Cheng Ding , Ying Guo","doi":"10.1016/j.wneu.2024.11.047","DOIUrl":"10.1016/j.wneu.2024.11.047","url":null,"abstract":"<div><h3>Background</h3><div>Chiasmatic cavernous hemangioma (CCH) is a rare disease. Most cases are treated with surgical resection through approaches such as pterional and orbitozygomatic craniotomy. However, with advancements in surgical technique and heightened patient demand for improved postoperative quality of life, there have been reports in recent years exploring more minimally invasive surgical approaches, such as the subfrontal trans-eyebrow keyhole and endoscopic endonasal transsphenoidal approach. In this article, the cases of CCH in the reported literature are reviewed, the indications and techniques of minimally invasive surgery for the removal of CCH through the subfrontal trans-eyebrow keyhole approach are discussed, and the effects of different surgical approaches are analyzed.</div></div><div><h3>Methods</h3><div>We reviewed the literature on surgical cases of intracranial cavernous hemangiomas (with chiasma as the center) involving the visual pathway published from 2000 to 2023 in PubMed and other relevant databases; ultimately, 55 cases from 37 articles were retrieved, to which we added an additional case, making the total number of cases examined 56. We analyzed the patient's medical records, including pathological symptoms, relationship with the chiasma location, surgical approach, and prognosis.</div></div><div><h3>Results</h3><div>The analysis of the data of 56 cases indicated that most patients experienced a decrease in visual acuity (64.3%) and visual-field defects (58.9%). Gradual changes in pituitary function were also observed (43.8%). The surgical approach is determined by the location of the lesion. Over the past 5 years, although the pterional (46.4%) approach has remained the most common, the proportion of subfrontal (12.5%) approaches has gradually increased. In the case we report, we found that the lesion in the patient involved the anterior chiasma and the right medial optic nerve. The patient presented with acute visual deterioration, suggesting the possibility of hemorrhage in the hemangioma. We attempted the right-sided subfrontal trans-eyebrow keyhole approach and achieved complete resection of the cavernous hemangioma. Postoperatively, the patient showed improvement in visual acuity and visual field, with obvious recovery observed at the 3-month follow-up.</div></div><div><h3>Conclusions</h3><div>According to our results, the subfrontal trans-eyebrow keyhole approach for the resection of CCH is mainly suitable for cases in which the lesions are located above and anterior to the optic chiasm, the medial or superior aspect of the intracranial segment of the optic nerve is involved, and there is no invasion into the optic nerve canal. Compared with the traditional surgical approach, the minimally invasive subfrontal trans-eyebrow keyhole approach has demonstrated better clinical outcomes in the resection of CCH. However, according to the specific conditions of different patients, it is still necessary to com","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":"194 ","pages":"Article 123464"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pan Zhou , Xin Li , Gang-gang Peng , Hao-fei Hu , Zhe Deng
{"title":"Nonlinear Relationship Between Blood Urea Nitrogen to Albumin Ratio and 3-Month Outcomes in Patients With Acute Ischemic Stroke: A Second Analysis Based on a Prospective Cohort Study","authors":"Pan Zhou , Xin Li , Gang-gang Peng , Hao-fei Hu , Zhe Deng","doi":"10.1016/j.wneu.2024.11.035","DOIUrl":"10.1016/j.wneu.2024.11.035","url":null,"abstract":"<div><h3>Objective</h3><div>Patients with acute ischemic stroke (AIS) have limited evidence regarding the relationship between blood urea nitrogen and albumin. Aiming to investigate the relationship between the blood urea nitrogen to albumin ratio (BUN/ALB ratio) and poor outcomes in AIS patients at 3 months was the purpose of this study.</div></div><div><h3>Methods</h3><div>AIS participants at a Korean hospital from January 2010 to December 2016 were included in a secondary analysis of a prospective cohort study. Logistic regression and restricted cubic splines were used to examine the relationship between BUN/ALB ratio and poor outcomes after 3 months.</div></div><div><h3>Results</h3><div>There is a skewed distribution of BUN/ALB ratios, ranging from 0.114 to 1.250. Model II of the binary logistic regression showed that the BUN/ALB ratio was not statistically significant in predicting poor outcomes for AIS patients after 3 months. However, there was a notable nonlinear relationship between them, with the inflection point of the BUN/ALB ratio identified as 0.326. The BUN/ALB ratio on the left side of the inflection point was associated with a 42% reduction in 3-month poor outcomes (odds ratio = 0.58, 95% confidence interval: 0.40 to 0.83). Conversely, the relationship was not statistically significant on the right side of the inflection point.</div></div><div><h3>Conclusions</h3><div>The BUN/ALB ratio and poor outcomes in AIS patients show a nonlinear correlation. For AIS patients, a BUN/ALB ratio of approximately 0.326 is associated with the lowest risk of adverse outcomes at 3 months. Specifically, for nonsmoking AIS patients, a BUN/ALB ratio of approximately 0.295 is associated with the lowest risk of adverse outcomes at 3 months.</div></div>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":"194 ","pages":"Article 123452"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hector R. Martinez , Carlos D. Acevedo-Castillo , Hannia M. Macias-Cruz , Uriel A. Bautista-Coronado , Omar R. Ortega-Ruiz , Alan Cornejo-Hernandez , Patricio Naranjo-Hernández , Paulo M. Tabera-Tarello , Jose A. Moran-Guerrero , Jose A. Figueroa-Sanchez
{"title":"Extracranial Carotid Artery Aneurysms: A Comprehensive Analysis of its Epidemiology, Pathogenesis, Diagnosis, and Management: A Scoping Review","authors":"Hector R. Martinez , Carlos D. Acevedo-Castillo , Hannia M. Macias-Cruz , Uriel A. Bautista-Coronado , Omar R. Ortega-Ruiz , Alan Cornejo-Hernandez , Patricio Naranjo-Hernández , Paulo M. Tabera-Tarello , Jose A. Moran-Guerrero , Jose A. Figueroa-Sanchez","doi":"10.1016/j.wneu.2024.11.111","DOIUrl":"10.1016/j.wneu.2024.11.111","url":null,"abstract":"<div><h3>Background</h3><div>Extracranial carotid artery aneurysms (ECAAs) are extraordinarily rare, representing approximately 0.4%–4% of all extracranial artery aneurysms. As medical technology has advanced, new approaches for ECAAs treatment can be performed. Nevertheless, there is currently no consensus on the best therapeutic approach due to the information scarcity.</div></div><div><h3>Methods</h3><div>We performed a systematic review of all published ECAA cases in Scopus, Medline, Web of Science, and Google Scholar to retrieve all available studies up to March 2024.</div></div><div><h3>Results</h3><div>Eighty-eight studies reporting on a total of 359 patients presenting ECAAs were included. The mean age at diagnosis was 53 years. Most patients were male (58.4%). The primary presenting symptoms were pulsatile mass (31.2%), ischemia (24.7%), pain (9.75%), and dizziness (8.36%). Overall, the leading etiologies of aneurysms were atherosclerosis (34.2%), trauma (10%), and vasculitis (5.57%). Surgery was performed in 68.5% of patients, 26.7% underwent endovascular procedures, and 3.9% received conservative management.</div></div><div><h3>Conclusions</h3><div>ECAAs are a rare clinical condition. However, a great percentage of patients could present with ischemic symptoms. Similarly, cardiovascular risk factors present as the most prevalent comorbid conditions associated with these vascular aberrancies. With this systematic review, we seek to provide insight into extracranial carotid aneurysms, identifying areas of opportunity in both the diagnosis and management of this pathology and the standardization of clinical reporting and case classification. These findings underscore the need for future research to improve the understanding and approach to this complex clinical condition.</div></div>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":"194 ","pages":"Article 123528"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142755734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}