World neurosurgery最新文献

{"title":"Redefining Ventricular Access Landmarks: A Novel Approach Using Magnetic Resonance Imaging and 3-Dimensional Reconstructions for Keen's Point Trajectories.","authors":"Shahin Naghizadeh, Maryam Zohrabi-Fard, Saeed Oraee-Yazdani","doi":"10.1016/j.wneu.2024.11.065","DOIUrl":"10.1016/j.wneu.2024.11.065","url":null,"abstract":"<p><strong>Background: </strong>Cerebrospinal fluid diversion via shunt placement is a common neurosurgical intervention. Keen's Point is a widely used landmark for accessing the trigone of the lateral ventricle; however, it lacks clinical validation. This study re-evaluates Keen's Point scalp parameters using magnetic resonance imaging (MRI) to identify an ideal shunt entry point based on 3-dimensional reconstructions.</p><p><strong>Methods: </strong>MRI data from 36 Parkinson disease patients scheduled for deep brain stimulation were analyzed. The optimal ventricular puncture site (A Point) was identified on axial MRI images and mapped to the scalp. Distances from A Point to a perpendicular line from the external auditory meatus (B Point) and from B Point to the pinna and external auditory meatus were measured. The Posterior Callosal Angle (PCA) was calculated to assess its correlation with the distance between A and B points. Statistical analysis used regression and t-tests (P < 0.05).</p><p><strong>Results: </strong>After excluding patients with PCA outside 70°-100°, 24 patients remained. The optimal distance from B Point to A Point significantly increased from 25-30 mm (as described by Keen) to 56.89 ± 1.36 mm (P < 0.01). Average PCA angle (85°) correlates with a distance of ∼57 mm, and a significant negative correlation was found between PCA and the distance from A Point to B Point (r = -0.42, P < 0.03).</p><p><strong>Conclusions: </strong>This modified Keen's Point is a reliable landmark for ventriculostomy. Incorporating PCA into preoperative planning enhances catheter placement accuracy, providing a prominent approach to shunting at Keen's Point.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"123482"},"PeriodicalIF":1.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142692463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Awake Minimally Invasive Surgery Transforaminal Lumbar Interbody Fusion Under Spinal Anesthesia: Screw Placement Accuracy and 1 Year Follow-Up.","authors":"Gaetano De Biase, Benjamin F Gruenbaum, Elird Bojaxhi, Jennifer S Patterson, Katherine Sabetta, Alfredo Quinones-Hinojosa, Kingsley Abode-Iyamah","doi":"10.1016/j.wneu.2024.11.061","DOIUrl":"10.1016/j.wneu.2024.11.061","url":null,"abstract":"<p><strong>Objective: </strong>We assessed the accuracy of pedicle screws placed during awake minimally invasive surgery (MIS) transforaminal lumbar interbody fusion (TLIF) under spinal anesthesia and analyzed outcomes at the 1-year follow-up.</p><p><strong>Methods: </strong>We included patients who underwent awake MIS-TLIF under spinal anesthesia at an academic center from February 2020 to February 2022. The Gertzbein-Robbins classification was used for screw accuracy rating.</p><p><strong>Results: </strong>A total of 100 pedicle screws were inserted in 24 patients, with the most common level being L4-5. Median age was 63.5 ± 16.5 (interquartile range) years, 42% male, median body mass index 28 ± 6 kg/m², and median American Society of Anesthesiologists class was 2 ± 1. Two patients underwent a 2-level fusion, and 22 patients underwent a 1-level fusion. Median estimated blood loss was 35 ± 25 mL, median length of stay was 0 ± 1 day, with 54% of patients going home on the day of surgery, and the only intraoperative complication was 1 durotomy. Median procedure time was 112 ± 23.5 minutes, and median operating room time (including the spinal block) was 159.5 ± 32.7 minutes; 67% of the screws were placed with navigation, and 33% were robotic-assisted (Mazor X); 99% of the screws were Gertzbein Robins grade A, and 1% grade E. At the 1 year follow-up, computed tomography showed no evidence of pseudarthrosis, and all patients reported improvement in their presenting symptoms.</p><p><strong>Conclusions: </strong>Our study shows a high accuracy (99%) of pedicle screw placement in patients undergoing awake MIS-TLIF under spinal anesthesia and significant improvement of their symptoms at 1-year follow-up.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"123478"},"PeriodicalIF":1.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anatomical Targeting of the Superior Cervical Ganglion on Computed Tomography Imaging for Guidance of Endovascular Transmural Intervention.","authors":"Xin Qi, Wi Jin Kim, Hasitha M Samarage, Keshav Goel, David Zarrin, Kambiz Nael, Anthony C Wang, Jeremiah Johnson, Geoffrey P Colby","doi":"10.1016/j.wneu.2024.11.044","DOIUrl":"10.1016/j.wneu.2024.11.044","url":null,"abstract":"<p><strong>Background: </strong>Endovascular transmural targeting of cervical and cranial perivascular structures is a novel approach for minimally invasive delivery of therapeutics. Components of the autonomic nervous system are in close anatomic proximity to major cervical vasculature and, therefore, represent potential targets for intervention. The superior cervical ganglion (SCG) is a discrete structure of interest for this approach, as sympathetic blockade may have therapeutic effects for various conditions. Variability of SCG location and its relationship to large cervical vessels, and the feasibility of endovascular transmural targeting has not been elucidated.</p><p><strong>Methods: </strong>In this retrospective study, computed tomography angiography of head and neck from patients with subarachnoid hemorrhage or cerebral aneurysms were reviewed. SCG dimensions and spatial relationship to cervical vessels were measured. Measured anatomic parameters were used to determine endovascular transmural accessibility of the SCG from various cervical vessels.</p><p><strong>Results: </strong>A total of 159 SCGs were identified and measured from 314 unilateral neck images of sufficient quality. SCGs had an average radio-opacity of 49.6 Hounsfield Units, length of 1.91 cm, and width of 0.71 cm. Internal carotid artery (ICA) has the longest contact length with the SCG (mean = 1.80 cm) compared to other major cervical vessels. A total of 95% of SCGs were accessible from ICA using an endovascular transmural approach, with the majority of SCGs located anteromedially to the ICA.</p><p><strong>Conclusions: </strong>This is the first anatomical study to provide pertinent targeting information for endovascular transmural access to the SCG using computed tomography angiography. In most cases, endovascular transmural access to the SCG is anatomically feasible from the proximal cervical ICA.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"123461"},"PeriodicalIF":1.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of Symptomatic Intracranial Hemorrhage Before Mechanical Thrombectomy Using Machine Learning in Patients with Anterior Circulation Large Vessel Occlusion.","authors":"Haydn Hoffman, Joel Sequeiros Chirinos, Nickalus Khan, Christopher Nickele, Violiza Inoa, Lucas Elijovich, Cheran Elangovan, Balaji Krishnaiah, Daniel Hoit, Adam S Arthur, Nitin Goyal","doi":"10.1016/j.wneu.2024.11.038","DOIUrl":"10.1016/j.wneu.2024.11.038","url":null,"abstract":"<p><strong>Background: </strong>Symptomatic intracranial hemorrhage (sICH) after mechanical thrombectomy (MT) is associated with worse outcomes. We sought to develop and internally validate a machine learning (ML) model to predict sICH prior to MT in patients with anterior circulation large vessel occlusion.</p><p><strong>Methods: </strong>Consecutive adults who underwent MT for internal carotid artery/M1/M2 occlusions at a single institution were reviewed. The data was split into 80% training and 20% hold-out test sets. 9 ML models were screened. The top performing ML model was compared to logistic regression and previously described clinical prediction models. SHapley Additive exPlanations were used to identify the most predictive features in the ML model.</p><p><strong>Results: </strong>A total of 497 patients met inclusion criteria. The top performing ML model was extreme gradient boosting. The area under the receiver operating characteristics curve for the ML model on the test set was 0.79 (95% confidence interval [CI] 0.67-0.89), which was significantly higher (P < 0.001) than the logistic regression model (0.54 [95% CI 0.33-0.76]). The ML model also performed significantly better than the TAG = TICI-ASPECTS-glucose score (0.69 [95% CI 0.55-0.85], P < 0.001), Systolic blood pressure-Time-Blood glucose-ASPECTS score (0.45 [95% CI 0.30-0.60], P < 0.001), and ChatGPT 4.0 (0.60 [95% CI 0.48-0.68], P < 0.001). Based on SHapley Additive exPlanations values the most predictive features of sICH in the ML model were lower Alberta Stroke Program Early CT score, lower collateral score, and higher presenting National Institutes of Health Stroke Scale.</p><p><strong>Conclusions: </strong>An ML model accurately predicted sICH prior to MT. It performed better than a standard statistical model and previously described clinical prediction models.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"123455"},"PeriodicalIF":1.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphometric Analysis of Radiological Features of Pituitary Tumors and Optic Pathway Distortion Associated with Visual Impairment in Pituitary Macroadenomas with Suprasellar Extension.","authors":"Chia-Yu Chen, Jin-Shuen Chen, Yao-Shen Chen, Chun-Hao Yin, Po-Chin Wang, Shuo-Hsiu Hsu, Yao-Chung Yang, Wei-Chuan Liao","doi":"10.1016/j.wneu.2024.11.019","DOIUrl":"10.1016/j.wneu.2024.11.019","url":null,"abstract":"<p><strong>Objective: </strong>To validate the correlation between visual impairment (VI) and suprasellar extension (SSE) in pituitary macroadenomas and to identify patients at heightened risk of preoperative visual deficits by analyzing anatomical distortion of optic nerve and optic chiasm (OC) using preoperative magnetic resonance imaging.</p><p><strong>Methods: </strong>Ninety-seven patients with pituitary macroadenomas and SSE, treated between January 2015 and April 2022, were analyzed. Associations between VI, demographic data, SSE, and optic pathway deformation were assessed. SSE cutoff points for predicting VI were determined using receiver operating characteristic curves, with univariate and multivariate logistic regression identifying potential risk factors.</p><p><strong>Results: </strong>Of the 97 patients, 47 had confirmed VI. Independent predictors of VI included visual symptoms lasting >1 month, sagittal SSE >10.35 mm, and vertical OC width >5.6 mm. Additional risk factors were older age, nonfunctioning pituitary adenoma, coronal SSE, dumbbell-shaped tumors, large and giant adenomas, reduced optic nerve diameter, increased horizontal OC width, and thinned OC thickness.</p><p><strong>Conclusions: </strong>Tumor morphology and optic pathway distortion predict preoperative VI in patients with pituitary macroadenomas. These findings support the development of a viable approach for assessing VI risk in clinical practice, aiding in decisions regarding optimal surgical timing.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"123436"},"PeriodicalIF":1.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survival Analysis of Glioblastoma: A Scientometric Perspective.","authors":"Zahra Alirezaei, Alireza Amouheidari, Reza BasirianJahromi, Shohreh Seyyedhosseini, Ali Hamidi","doi":"10.1016/j.wneu.2024.11.059","DOIUrl":"10.1016/j.wneu.2024.11.059","url":null,"abstract":"<p><strong>Background: </strong>Glioblastoma is the most aggressive primary brain tumor and the outlook for patients is usually pessimistic. Numerous ongoing studies have focused on enhancing the survival rate of glioblastoma patients. This study aims to analyze the research trends surrounding glioblastoma survival and facilitate studying recent topics to provide insight into the perspective, research fields, and international collaborations.</p><p><strong>Methods: </strong>Data were collected from the Web of Science database documents published from 1980 to 2022 and analyzed using Citespace and Biblioshiny software. After analyzing the data, we visualized the co-occurrence and coauthorship networks.</p><p><strong>Results: </strong>Eighteen main clusters were formed by drawing a document cocitation network. The result indicates that prognostic biomarkers, treating field, T cell, radiomic feature, and 5-aminolevulinic acid were trending topics for researchers. The most active countries in this field are the United States, followed by China, Germany, and Italy, respectively.</p><p><strong>Conclusions: </strong>Considering the significance of monitoring the studies in glioblastoma patients, the current research has shown promising results in stratifying patient survival as a valuable tool for prognosis and prediction and eventually guiding treatment decisions. Using the results of this study, glioblastoma researchers can identify their potential colleagues and research gaps in this field.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"123476"},"PeriodicalIF":1.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum C-reactive protein-to-albumin ratio as a clinical risk factor for traumatic spinal cord injury.","authors":"Erxing Tao, Zhixin Liu, Yihao Liu, Chengyun Wang, Genbo Huang, Chunhua Xu, Zihan Ding","doi":"10.1016/j.wneu.2024.12.005","DOIUrl":"https://doi.org/10.1016/j.wneu.2024.12.005","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effects of admission serum C-reactive protein-to-albumin ratio (CAR) in traumatic spinal cord injury (TSCI) severity evaluation and prognosis.</p><p><strong>Methods: </strong>We included 402 TSCI patients from two hospitals and collected relevant clinical and laboratory data. The effects of CAR on the prognosis of TSCI were explored using univariate and multivariate logistic regression analyses. The predictive values of different indicators were compared by evaluating the areas under the receiver operating characteristic curve (AUC).</p><p><strong>Results: </strong>We classified 224 (55.7%) patients as severe TSCI (AIS grades A-B), and 178 (44.3%) patients as non-severe TSCI (AIS grades C-E) according to the American Spinal Cord Injury Society Impairment Scale (AIS). Further investigation into the correlation between CRP, CAR, and serum albumin with the AIS grade showed that the admission CRP and CAR decreased in an AIS grade-dependent manner, while serum albumin increased in an AIS grade-dependent manner. Of the total patients, 226 (56.2%) were categorised as having a good clinical outcome based on AIS grade at the 1-year follow-up. Serum CAR decreased as follow-up AIS grade decreased. Serum CAR was more strongly correlated with follow-up AIS grade than serum CRP and serum albumin alone. Multivariate logistic regression analyses showed that injury severity and CAR were independent risk factors for poor prognosis. The AUC of serum CAR was 0.749 higher than that of serum CRP (AUC=0.736) and serum albumin (AUC=0.719).</p><p><strong>Conclusion: </strong>Serum CAR is a readily available biomarker for assessing the severity of TSCI and predicting prognosis, which is clinically relevant for the functional recovery of patients with TSCI.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic Review of Surgical Success, Complications, Revision Rates, Radiation Dosage, and Operative Time of 3D-Navigated vs. Non-Navigated Spinal Procedures.","authors":"Ikaasa Suri, Bahie Ezzat, Sayahi Suthakaran, Juan Arroyave, Daniel Kwon, Lily Martin, James Hu, Kurt Yaeger, Matthew Carr","doi":"10.1016/j.wneu.2024.12.009","DOIUrl":"https://doi.org/10.1016/j.wneu.2024.12.009","url":null,"abstract":"<p><strong>Objectives: </strong>3D navigation offers real-time guidance in surgery. However, there is limited and inconsistent data regarding the usability, safety, and efficacy. To address gaps in knowledge about 3D navigation in spinal surgery, we conducted a comprehensive review of success rates, complications, revisions, radiation exposure, and operative time associated with FDA-approved 3D surgical navigation tools.</p><p><strong>Methods: </strong>This study adhered to PRISMA guidelines and used a protocol registered on PROSPERO (CRD42023404554). Ovid MEDLINE, Embase, and Cochrane Central Register of Controlled Trials databases were searched using relevant keywords for 3D surgical navigation and spinal procedures from 1946 to March 02, 2023. Two independent reviewers assessed the studies using inclusion/exclusion criteria and risk of bias tools. Statistical analyses included one-way ANOVA, weighted-mean difference, and unpaired t-tests with Welch's correction for associations and comparisons between groups, respectively.</p><p><strong>Results: </strong>Of the total 11,324 studies identified and 7,198 screened, 62 studies totaling 3,170 adult patients were included in this comprehensive review. Complication and surgical success rates have remained constant since 2004, with overall rates of 5.5% and 94.0%, respectively. When segmented by spinal region, complication rates may be moderately positively correlated with frequency of cervical and thoracic procedures (r = 0.25, p = 0.68). The most commonly reported complication was pedicle screw malposition or breach. A subset of 20 studies, totaling 1,554 patients, compared the performance of 3D navigation to 2D fluoroscopy or freehand navigation. There was a significant difference of 6.53% between surgical success rates of the 3D-navigated and control groups (p = 0.03). However, there was no significant difference in radiation exposure or operative time.</p><p><strong>Conclusions: </strong>3D navigation in spinal procedures has higher surgical success rates than 2D fluoroscopy and freehand navigation. Included studies exhibited varying limitations, including no patient follow-up (n = 1), less than 10 patients (n = 6), various types of spinal disorders (n = 1), and varying comorbidities among participants (n = 2). Improving 3D navigation tools remains imperative to decrease operative time and radiation exposure.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing Pedicle Screw Fixation Training: A Novel Approach Using Head-mounted Devices for Video-assisted Debriefing.","authors":"Yuming Wang, Xia Zhang, Xiangsheng Tang, Ruichen Jiang, Shuyue Yang, Yanzhu Shen, Ping Yi","doi":"10.1016/j.wneu.2024.11.007","DOIUrl":"10.1016/j.wneu.2024.11.007","url":null,"abstract":"<p><strong>Background: </strong>Video-assisted debriefing (VAD) is promising for medical skill training, but its effectiveness requires further exploration. The aim of this study was to investigate the effectiveness of point-of-view VAD in spinal surgery training.</p><p><strong>Methods: </strong>Forty surgical residents were randomly divided into control and video-assisted (VA) groups, both of which underwent pedicle screw fixation procedures while being graded by a consulting surgeon in terms of their technical skills (primary outcome). On the second day, both groups received verbal debriefing and coaching from a senior consultant surgeon; for the VA group, this step was performed while watching a recorded point-of-view video of the procedure alongside the resident surgeon. Both groups then underwent a new testing round and participated in a questionnaire survey regarding their debriefing experience.</p><p><strong>Results: </strong>After the debriefing session, the residents in the VA group had significantly greater technical skills than those in the control group (37 ± 9.7 vs. 25 ± 8.5, P < 0.001). The VAD method was better than the traditional method in terms of steps such as recognizing anatomical structures, piloting holes in the bone, tapping, screw insertion and judging the location of the pedicle screws.</p><p><strong>Conclusions: </strong>VAD is more effective than traditional verbal debriefing for improving residents' surgical skills, particularly for obtaining a more comprehensive understanding of anatomical structures, imitating detailed surgical techniques as well as promoting initiative. However, in terms of mastery of surgical skills, VAD is not significantly beneficial for tactile perception of the surrounding tissue, indicating that a certain amount of practice is still necessary.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"123424"},"PeriodicalIF":1.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global Trends of Mechanical Thrombectomy in Acute Ischemic Stroke Over the Past Decade: A Scientometric Analysis Based on WOSCC and GBD Database.","authors":"Mingfen Wu, Zijun He, Kefu Yu, Luofei Zhang, Zhigang Zhao, Bin Zhu","doi":"10.1016/j.wneu.2024.11.045","DOIUrl":"10.1016/j.wneu.2024.11.045","url":null,"abstract":"<p><strong>Objective: </strong>To present a global overview of the current research landscape and emerging trends in mechanical thrombectomy for acute ischemic stroke (AIS) over the past decade.</p><p><strong>Methods: </strong>A thorough search was conducted on the Web of Science on May 20, 2024, focusing on original articles and reviews in English. Bibliometric tools were employed to make a network analysis and visual representation. Additionally, data on disability-adjusted life years, prevalence, and incidence of ischemic strokes were extracted from the Global Burden of Disease database.</p><p><strong>Results: </strong>A total of 7776 papers were included, indicating a steady increase from 169 to 1311 between 2014 and 2023. The United States led in core publications with 2887 papers. The incidence and disability-adjusted life years of ischemic stroke have continued to rise in Asia but have recently declined in North America and European countries. The University of Calgary emerged as the leading institution and Mayank Goyal was the most prolific author. Neurointerventional Surgery was the top contributing journal with 790 articles. The analysis identified 6332 keywords forming 5 clusters, with \"mechanical thrombectomy\" serving as the largest cluster, focusing mainly on interventional thrombectomy techniques for AIS. The term \"tissue plasminogen activator\" exhibited strong burst strength of 46.58. Keywords such as \"injury\", \"diagnosis\", \"posterior circulation\", and \"severity\" burst in 2020 and lasted until 2024.</p><p><strong>Conclusions: </strong>Interest in mechanical thrombectomy for AIS was progressively increasing. Future research directions may include minimizing intraoperative injuries, refining diagnostic techniques, investigating interventions for posterior circulation, and tailoring thrombectomy strategies based on stroke severity and large vessel occlusion etiology.</p>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":" ","pages":"123462"},"PeriodicalIF":1.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}