Journal of the Portuguese Society of Dermatology and Venereology最新文献_第9页

Sentinel Lymph Node Biopsy in Head and Neck Cutaneous Malignant Melanoma 头颈部皮肤恶性黑色素瘤前哨淋巴结活检

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2019-07-12 DOI: 10.29021/SPDV.77.2.1055

A. António, C. Moura, C. Semedo, S. Bitoque, Mariluz Martins, M. Vilares, M. Pecegueiro, J. Santos

{"title":"Sentinel Lymph Node Biopsy in Head and Neck Cutaneous Malignant Melanoma","authors":"A. António, C. Moura, C. Semedo, S. Bitoque, Mariluz Martins, M. Vilares, M. Pecegueiro, J. Santos","doi":"10.29021/SPDV.77.2.1055","DOIUrl":"https://doi.org/10.29021/SPDV.77.2.1055","url":null,"abstract":"Introduction: Sentinel lymph node biopsy (SLNB) is the standard of care for cutaneous melanoma, including head and neck melanoma. The aim of this study was to analyze and characterize SLNB in a population of head and neck melanoma patients. \u0000Methods: A unicentric, retrospective study on patients with cutaneous head and neck melanoma who underwent SLNB in the Department of Head and Neck Surgery at the Portuguese Institute of Oncology (IPO) Lisbon between January 2010 and December 2017 was performed. The location of primary melanoma, the identification of SLN, the number of the excised SLN, its lymphatic basin origin and the presence of infraclinic metastasis were analysed. \u0000Results: Ninety-eight patients were eligible to undergo SLNB during the observation period. The most frequent locations of primary melanoma were the scalp (24.5%) and the auricular and periauricular region (23.5%) and the most frequent variants were the superficial spreading melanoma (40.8%) and nodular melanoma (30.6%). SLNB was successfully executed in 78 patients (79.6%). A mean of 3.8 lymph-nodes per patient were excised and in 16.7% SLN were excised in more than one lymphatic basin. The SLN were identified in parotid region (39.8%), level II (29.5%) and level V (18.2%). SLN metastases were detected in 13 patients (16.7%). \u0000Conclusion: Surgical approach of head and neck cutaneous melanoma is particularly complex. The redundancy of lymphatic system, the multiple SLN and SLN basins influence the SLNB success and may contribute to high rates of false-negatives with its prognostic implications. All patients should be carefully monitored. ","PeriodicalId":238976,"journal":{"name":"Journal of the Portuguese Society of Dermatology and Venereology","volume":"147 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116384717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pustular Eruptions in Children as Manifestations of Autoinflammatory Diseases 儿童脓疱疹是自身炎症性疾病的表现

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2019-07-12 DOI: 10.29021/SPDV.77.2.1066

F. Santiago, A. Torrelo

引用次数: 1

Topical Immunomodulation with Diphenlycyclopropenone for Alopecia Areata 二苯环丙烯局部免疫调节治疗斑秃

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2019-07-12 DOI: 10.29021/SPDV.77.2.1074

A. Borges, A. Brasileiro, R. Pinheiro, A. Lencastre

{"title":"Topical Immunomodulation with Diphenlycyclopropenone for Alopecia Areata","authors":"A. Borges, A. Brasileiro, R. Pinheiro, A. Lencastre","doi":"10.29021/SPDV.77.2.1074","DOIUrl":"https://doi.org/10.29021/SPDV.77.2.1074","url":null,"abstract":"Introduction: Topical immunotherapy with diphenylcyclopropenone is a treatment option for patients with refractory or extensive alopecia areata. The aim of this study was to evaluate the clinical efficacy and tolerability of diphenylcyclopropenone therapy, in patients with alopecia areata, and identify possible prognostic factors that predict response to treatment. \u0000Methods: We conducted a retrospective study that included all patients diagnosed with alopecia areata and treated with diphenylcyclopropenone at our Department. \u0000Results: Twenty one patients were included for analysis (15 females and 6 males). Overall, nine patients (42.9%) had some hair regrowth with diphenylcyclopropenone therapy. Of these, five (55.6%) achieved pigmented terminal hair regrowth but with persistent patches of alopecia. Only one patient achieved > 90% of hair regrowth. Older age at onset, broader extent of alopecia at baseline and presence of nail dystrophy were all negative prognostic factors (p < 0.05). Atopy and thyroid dysfunction were not statistically significant as predictors of poor treatment outcome. Adverse effects were documented in 15 patients, most of them were mild and did not lead to treatment interruption. \u0000Conclusion: Diphenylcyclopropenone therapy is a viable treatment option in patients with extensive alopecia areata, although the response is partial in the majority of the cases. Limitations of this study include its retrospective nature and the limited number of patients.","PeriodicalId":238976,"journal":{"name":"Journal of the Portuguese Society of Dermatology and Venereology","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128220993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Melanoma Maligno Cutâneo: Estudo Retrospetivo de Sete Anos (2011-2017) 皮肤恶性黑色素瘤:7年回顾性研究(2011-2017)

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2019-07-12 DOI: 10.29021/SPDV.77.2.1065

F. Almeida, Regina Caldas, Pedro Oliveira, C. Brito

{"title":"Melanoma Maligno Cutâneo: Estudo Retrospetivo de Sete Anos (2011-2017)","authors":"F. Almeida, Regina Caldas, Pedro Oliveira, C. Brito","doi":"10.29021/SPDV.77.2.1065","DOIUrl":"https://doi.org/10.29021/SPDV.77.2.1065","url":null,"abstract":"Introdução: O melanoma maligno é uma neoplasia cutânea muito agressiva, com uma incidência crescente nos últimos anos. Material e Métodos: Realizou-se estudo retrospetivo através da análise de processos clínicos de doentes com o diagnóstico de melanoma maligno cutâneo, durante o período compreendido entre 2011 e 2017. Analisaram-se características epidemiológicas, clínicas e histopatológicas e comparou-se com um estudo prévio de 11 anos realizado nesta Instituição (1999 a 2009). Resultados: O melanoma maligno cutâneo foi diagnosticado em 163 doentes, 59,5% do sexo feminino e 40,5% do sexo masculino, cuja idade média foi de 65,6 anos. A localização anatómica mais frequente nos homens foi o tronco, enquanto nas mulheres foi a perna. O subtipo de melanoma maligno cutâneo mais comum foi o de extensão superficial, seguindo-se o lentigo maligno e o nodular. A maioria dos casos eram melonoma maligno cutâneo invasivos (67,5%), em oposição aos melanomas malignos cutâneos in situ (32,5%). A média do índice de Breslow foi de 3,01 mm. Destaca-se o aumento do número de doentes com melanoma maligno cutâneo, já que no estudo anterior apenas tinham sido diagnosticados 129 casos. Conclusão: Os resultados obtidos neste estudo estão de acordo com o descrito na literatura, nomeadamente no que se refere à faixa etária dos doentes, e à localização anatómica e subtipo predominante do melanoma maligno cutâneo. Verificou-se um aumento do número de casos localizados na cabeça e tronco face aos membros inferiores. Apesar do investimento na deteção do melanoma maligno cutâneo, o aumento do número de diagnósticos não parece contrabalançar o risco global de melanoma maligno cutâneo, uma vez que continuam a surgir muitos casos, predominantemente invasivos e espessos.","PeriodicalId":238976,"journal":{"name":"Journal of the Portuguese Society of Dermatology and Venereology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129812246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Presente e Futuro da Revista da Sociedade Portuguesa de Dermatologia e Venereologia

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2019-07-12 DOI: 10.29021/SPDV.77.2.1090

H. Donato

引用次数: 0

The Different Faces of Angioedema: Classification, Diagnosis and Management 血管性水肿的不同面貌:分类、诊断和治疗

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2019-07-12 DOI: 10.29021/SPDV.77.2.1064

M. Batista, F. Alves, M. Gonçalo

引用次数: 2

Lesões Bolhosas Palmares no Idoso 老年人手掌大疱性病变

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2019-07-12 DOI: 10.29021/SPDV.77.2.1061

L. Santiago, José Carlos Cardoso, Ó. Tellechea

{"title":"Lesões Bolhosas Palmares no Idoso","authors":"L. Santiago, José Carlos Cardoso, Ó. Tellechea","doi":"10.29021/SPDV.77.2.1061","DOIUrl":"https://doi.org/10.29021/SPDV.77.2.1061","url":null,"abstract":"Relatamos o caso de um homem de 79 anos com história de lesões vesiculosas e bolhosas pruriginosas localizadas a nível palmar bilateral. Referia aparecimento há cerca de 2 anos, com resposta parcial a dermocorticóides de baixa-média potência e carácter recidivante. Ao exame objetivo apresentava múltiplas lesões vesiculobolhosas tensas com base eritematosa, a maioria em fase erosiva (Fig. 1). A nível plantar referia lesões no passado, que não apresentava no momento da consulta. Não apresentava outras alterações cutâneas ou mucosas. Foi enviada amostra para cultura de fungos que foi negativa. O estudo histopatológico de biópsia cutânea mostrou descolamento bolhoso subepidérmico com extensa reepitilização subjacente associado a infiltrado linfomononucleado perivascular rico em eosinófilos (Fig. 2). A imunofluorescência direta (IFD) de área perilesional mostrou depósitos lineares de C3 e IgG ao nível da junção dermo- epidérmica. Foram detectados anticorpos circulantes para BP180 (122 U/mL, normal >20 U/mL) por ELISA. Foi iniciado tratamento com prednisolona 30 mg/dia em desmame durante 2 semanas associado a dermocorticóide de alta potência com resolução das lesões e sem formação de novas bolhas em dois anos de follow-up.","PeriodicalId":238976,"journal":{"name":"Journal of the Portuguese Society of Dermatology and Venereology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131107470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Caso Exuberante de Larva Migrans Cutânea 丰富的皮肤幼虫迁移案例

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2019-07-12 DOI: 10.29021/SPDV.77.2.1058

Felipe Tavares Rodrigues, Patrícia Regina Gomes Veríssimo de Faria Silva, Antônio Macedo D´Acri, C. J. Martins

{"title":"Caso Exuberante de Larva Migrans Cutânea","authors":"Felipe Tavares Rodrigues, Patrícia Regina Gomes Veríssimo de Faria Silva, Antônio Macedo D´Acri, C. J. Martins","doi":"10.29021/SPDV.77.2.1058","DOIUrl":"https://doi.org/10.29021/SPDV.77.2.1058","url":null,"abstract":"A larva migrans cutânea (LMC) é uma dermatozoonose caracterizada por uma erupção cutânea de lesões eritematosas, habitualmente com relevo, pápulo-vesiculosas, de distribuição linear ou serpiginosa e, na maioria das vezes, pruriginosa. É causada pela penetração e migração intraepidérmica de três possíveis espécies de larvas de nematóides. Os maiores índices de transmissão ocorrem nas regiões tropicais costeiras, onde as larvas podem migrar livremente em solos arenosos e onde, além disso, a temperatura quente e a humidade são ideais para a sua viabilidade. Relata-se o caso de um paciente do sexo masculino, de 51 anos, leucodérmico que desenvolveu uma dermatose pruriginosa, extensa, envolvendo dorso, flanco, fossa ilíaca e membro inferior, à direita. As lesões surgiram cerca de sete dias após a prática de desporto e lazer em terreno relvado. Após revisão da literatura científica, analisamos os aspectos epidemiológicos, parasitológicos, clínicos, laboratoriais e terapêuticos inerentes ao tema larva migrans cutânea é uma afecção dermatológica comum em países tropicais e subtropicais, sendo de suma importância o seu pronto reconhecimento e manejo terapêutico para uma cura rápida com baixo grau de morbidade.","PeriodicalId":238976,"journal":{"name":"Journal of the Portuguese Society of Dermatology and Venereology","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133472786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Piedra Branca por Trichosporon ovoides no Sudeste do Brasil: Relato e Breve Revisão da Literatura 巴西东南部卵形毛孢的白色皮德拉:文献报道和简要综述

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2019-07-12 DOI: 10.29021/spdv.77.2.1038

Flávia Regina Ferreira, Talita Pollo, Marina Thereza Fogo Pereira, Margareth Neila Prats Bueri

引用次数: 1

How to Perform Videos in Dermatologic Surgery? A Simple and Inexpensive Recording Technique 如何在皮肤外科中进行录像?一种简单而廉价的录音技术

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2019-07-12 DOI: 10.29021/SPDV.77.2.1044

B. Duarte, J. Goulão

{"title":"How to Perform Videos in Dermatologic Surgery? A Simple and Inexpensive Recording Technique","authors":"B. Duarte, J. Goulão","doi":"10.29021/SPDV.77.2.1044","DOIUrl":"https://doi.org/10.29021/SPDV.77.2.1044","url":null,"abstract":"Video recording surgical procedures is one of the most valuable tools for teaching and self-assessment in Dermatologic Surgery. A number of recording systems have been described in the literature. Nevertheless, they’re usually expensive (~500€) and time-consuming to prepare, the latter being a major disadvantage for a busy surgical speciality such as Dermatology. The authors describe a simple and inexpensive technique for surgical video capture in Dermatologic Surgery. For this setup, the surgeon needs only a smartphone with a camera (which is nowadays ubiquitous), a bike phone holder (10€ to 30€), an adjustable intravenous pole and, optionally, a powerbank. With the patient in position for the surgical intervention (seated or lying on his back on the surgical table, depending on the procedure), the bike phone holder should be attached to the vertically adjustable intravenous pole. The smartphone must be then set on the bike phone holder, with its “recording mode” already started. Optionally, a powerbank can also be attached to the intravenous pole to provide extra charge for longer procedures. The height of the intravenous pole, as well as its position and distance to the surgical table, should be adjusted accordingly before the intervention, in order to provide the best recording definition. The authors describe a simple, easy to setup, inexpensive system to record videos in Dermatologic Surgery.","PeriodicalId":238976,"journal":{"name":"Journal of the Portuguese Society of Dermatology and Venereology","volume":"365 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132641096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0