Journal of the Portuguese Society of Dermatology and Venereology最新文献

Atypical Presentation of Herpes Simplex 1 Virus in a COVID-19 Patient 1例COVID-19患者单纯疱疹1型病毒的不典型表现

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2021-12-27 DOI: 10.29021/spdv.79.4.1408

M. J. Guimarães, F. Azevedo, C. Lisboa

{"title":"Atypical Presentation of Herpes Simplex 1 Virus in a COVID-19 Patient","authors":"M. J. Guimarães, F. Azevedo, C. Lisboa","doi":"10.29021/spdv.79.4.1408","DOIUrl":"https://doi.org/10.29021/spdv.79.4.1408","url":null,"abstract":"A 74-year-old man with past medical history of obesity and type 2 diabetes mellitus was admitted for COVID-19 pneumonia. Due to unfavorable disease progression, ten days later, the patient was admitted to the intensive care unit and intubated, requiring periods of prone position and systemic corticosteroid treatment. During the following weeks, the patient developed several infectious complications successfully managed with systemic antibiotics and herpes simplex infection of the left upper lip, treated with acyclovir 400 mg twice daily for 10 days. Dermatology observation was requested 2 days after acyclovir cessation due to an infiltrative hyperkeratotic erythematous plaque with pustules on the right zygomatic region (see picture 1) that had been noticed 2 days before. Polymerase chain reaction (PCR)-testing of swab samples from the pustules was positive for herpes simplex virus (HSV) 1, with negativity for HSV 2 and for varicella-zoster virus (VZV). Blood and CSF fluid PCR were negative for HSV 1, HSV 2 and VZV. The patient restarted acyclovir (400 mg, thrice daily for 12 days) with significant improvement of the lesion (less infiltration and hyperkeratotic crusts) and negative PCR-testing for HSV1 DNA after treatment cessation (see picture 2). About 2 weeks later the lesion was completely healed leaving a minor atrophic scar.","PeriodicalId":238976,"journal":{"name":"Journal of the Portuguese Society of Dermatology and Venereology","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128654959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A New Vision about Folliculitis Decalvans and Lichen Planopilaris: Two Distinct Entities or a Continuous Phenotypic Spectrum? Decalvans毛囊炎和扁平苔藓的新认识:两个不同的实体还是连续的表型谱?

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2021-12-27 DOI: 10.29021/spdv.79.4.1389

A. Marcos-Pinto, Â. Roda, L. Soares-de-Almeida, R. Oliveira Soares

引用次数: 0

Topical Photodynamic Therapy as a Treatment Option for Periocular Bowen's Disease: A Case Report 局部光动力疗法作为眼周鲍文病的一种治疗选择:1例报告

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2021-12-27 DOI: 10.29021/spdv.79.4.1397

J. Reis, A. Machado, A. Coelho, V. Costa, M. Selores

引用次数: 0

Vulvar Diseases that Required a Biopsy: A Retrospective Study 需要活检的外阴疾病:一项回顾性研究

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2021-12-27 DOI: 10.29021/spdv.79.4.1411

R. Bouceiro-Mendes, M. Mendonça-Sanches, L. Soares-de-Almeida, I. Correia-Fonseca, J. Borges-da-Costa

{"title":"Vulvar Diseases that Required a Biopsy: A Retrospective Study","authors":"R. Bouceiro-Mendes, M. Mendonça-Sanches, L. Soares-de-Almeida, I. Correia-Fonseca, J. Borges-da-Costa","doi":"10.29021/spdv.79.4.1411","DOIUrl":"https://doi.org/10.29021/spdv.79.4.1411","url":null,"abstract":"\u0000 \u0000 \u0000Introduction: The vulvar area may be affected by many noninfectious conditions with similar clinical appearance, requiring a cutaneous biopsy. Our goal was to characterize the noninfectious vulvar diseases that required a biopsy in a southwestern Europe Central Hospital during a 10-year period. \u0000Methods: A retrospective study of all the noninfectious vulvar diseases with histological confirmation diagnosed in our institution was conducted between January 1, 2008 and December 31, 2017. \u0000Results: The sample included a total of 323 biopsies from 317 patients, aged between 11 and 98 years (mean age of 54.2 years). A total of 36 vulvar diseases was identified. Neoplastic conditions were the most frequently found, particularly melanotic macules (22.3%). The most frequent malignant tumor was vulvar intraepithelial neoplasia (6.2%) and squamous cell carcinoma (5.6%). The most common dermatosis was lichen sclerosus (12.7%). \u0000Conclusion: Neoplasms were the most frequently diagnosed conditions affecting the vulvar area that required a biopsy. Ruling out malignancy was also the main reason to perform a biopsy. This study highlights the variety of noninfectious diseases that may affect the vulva and require a biopsy. Since vulvar diseases may be serious and carry high levels of patient distress a correct understanding of these conditions is crucial. \u0000 \u0000 \u0000","PeriodicalId":238976,"journal":{"name":"Journal of the Portuguese Society of Dermatology and Venereology","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114893789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiologia e Avaliação de Métodos Diagnósticos em Micoses Superficiais em Serviço de Dermatologia de Hospital Público em Santos, Brasil 巴西桑托斯公立医院皮肤科浅表真菌病的流行病学和诊断方法评价

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2021-12-27 DOI: 10.29021/spdv.79.4.1413

Fernanda J. Bauer, L. Logullo, Elizabeth M. Heins, Sandra L. M. Dinato

{"title":"Epidemiologia e Avaliação de Métodos Diagnósticos em Micoses Superficiais em Serviço de Dermatologia de Hospital Público em Santos, Brasil","authors":"Fernanda J. Bauer, L. Logullo, Elizabeth M. Heins, Sandra L. M. Dinato","doi":"10.29021/spdv.79.4.1413","DOIUrl":"https://doi.org/10.29021/spdv.79.4.1413","url":null,"abstract":"\u0000 \u0000 \u0000Introdução: Micoses superficiais são infecções fúngicas causadas principalmente por dermatófitos, leveduras e fungos filamentosos não dermatófitos, que acometem as camadas mais superficiais da pele e seus anexos. Apresentam alta prevalência em todo o mundo.O objectivo deste estudo é avaliar a epidemiologia das micoses superficiais, assim como o índice de concordância entre o exame micológico direto e a cultura para fungos. \u0000Métodos: Trata-se de estudo retrospectivo realizado no ambulatório de Dermatologia de hospital terciário, num intervalo de 6 anos. Para a elu- cidação diagnóstica, foi realizada colheita de material através de raspagem ou curetagem, para posterior análise por exame micológico direto e cultura para fungos. \u0000Resultados: Foram incluídas 439 amostras de lesões suspeitas de micoses superficiais de 420 pacientes, 268 do sexo feminino (63,8% doentes) com a média de idade de 45,7 anos (dos 3 meses aos 95 anos), com o maior número de casos das unhas (43,4%) e pele glabra (24,1%). Em geral, o fungo mais encontrado na cultura foi o Trichophyton rubrum; no entanto, não houve esta concordância em todos os locais da pele estudados. O exame micológico direto apresentou associação significativamente estatística com a cultura (K=0,955), se eliminadas os casos em que houve contaminação da cultura. \u0000Conclusão: O uso do exame micológico direto e da cultura, como métodos diagnósticos na Dermatologia, é uma opção que fornece resultados satisfatórios e de baixo custo, favorecendo doentes e sistema de saúde. Este estudo permitiu descrever o perfil epidemiológico dos pacientes de um centro de Dermatologia de referência, com dados relevantes em relação ao nosso objetivo. A concordância entre o exame micológico direto e a cultura mostrou a confiabilidade dos métodos. \u0000 \u0000 \u0000","PeriodicalId":238976,"journal":{"name":"Journal of the Portuguese Society of Dermatology and Venereology","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124126422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Asymptomatic Nodules in a Child 儿童无症状结节

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2021-12-27 DOI: 10.29021/spdv.79.4.1399

R. Caldas, M. J. Guimarães, J. Pardal, J. Gomes

引用次数: 0

Criptococose Cutânea Primária em Paciente Imunocompetente: Um Relato de Caso 免疫能力患者的原发性皮肤隐球菌病:一个病例报告

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2021-12-27 DOI: 10.29021/spdv.79.4.1410

Nicole S. Aranha, José M. F. L. Moço, Cristiana A. Sassamoto, Karla C. K. Prigenzi

{"title":"Criptococose Cutânea Primária em Paciente Imunocompetente: Um Relato de Caso","authors":"Nicole S. Aranha, José M. F. L. Moço, Cristiana A. Sassamoto, Karla C. K. Prigenzi","doi":"10.29021/spdv.79.4.1410","DOIUrl":"https://doi.org/10.29021/spdv.79.4.1410","url":null,"abstract":"\u0000 \u0000 \u0000A criptococose é uma infecção sistémica causada por Cryptococcus neoformans, levedura oportunista encapsulada. Esta infeção ocorre principalmente em indivíduos imunocomprometidos e os sintomas variam de acordo com a integridade do sistema imunológico. A criptococose cutânea afeta aproximadamente 20% dos pacientes com criptococose disseminada, mas a criptococose cutânea primária (PCC) sem infecção sistémica é rara. \u0000Um paciente do sexo masculino de 76 anos, com doença pulmonar obstrutiva crónica, hipertensão arterial e dislipidemia, apresentou-se com placa cutânea inflamatória violácea com bolhas que progrediu apesar de ceftriaxone endovenoso por 7 dias, sem sucesso. A biópsia incisional revelou o diagnóstico histopatológico de criptococose cutânea. As lesões resolveram após tratamento com fluconazol 300 mg/dia durante 3 meses. Não se detectou doença sistémica e não havia qualquer evidência de imunossupressão. \u0000Enfatiza-se a importância da inclusão da criptococose cutânea no diagnóstico diferencial das lesões cutâneas, mesmo em pacientes sem terapia imunossupressora. As manifestações cutâneas da infecção podem ser o primeiro indício para uma doença disseminada, pelo que o seu reconhecimento precoce é fundamental para um bom prognóstico. \u0000 \u0000 \u0000","PeriodicalId":238976,"journal":{"name":"Journal of the Portuguese Society of Dermatology and Venereology","volume":"179 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123038038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Síndrome de Pele Sensível: Revisão da Literatura de uma Entidade Emergente 敏感皮肤综合征:一种新兴实体的文献综述

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2021-12-27 DOI: 10.29021/spdv.79.4.1417

Frederico Bonito, Diogo Cerejeira, A. Monteiro

引用次数: 0

Purpura Fulminans in a 20-Year-Old Female 一例20岁女性暴发性紫癜

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2021-12-27 DOI: 10.29021/spdv.79.4.1385

F. Alves, M. Brites, I. Coutinho

{"title":"Purpura Fulminans in a 20-Year-Old Female","authors":"F. Alves, M. Brites, I. Coutinho","doi":"10.29021/spdv.79.4.1385","DOIUrl":"https://doi.org/10.29021/spdv.79.4.1385","url":null,"abstract":"\u0000 \u0000 \u0000A previously healthy 20-year-old female presented with extensive retiform purpura located at the face, upper and lower limbs, one week after an episode of acute tonsillitis. Despite the exuberance of the cutaneous findings and progression to skin necrosis she had no accompanying symptoms. Laboratory investigation revealed a heterozygous protein C mutation (exon 9, c.1332G> C, p.Trp444Cys), accounting for a partial deficiency of this anticoagulant protein. The patient was started on broad spectrum antibiotics, anticoagulation and systemic corticosteroids, with no lesional progression and complete resolution of cutaneous ulceration within 6 months. \u0000This is a singular case of purpura fulminans, since two different causative factors precipitated the events. The previous tonsillitis reported by the patient is significant, because the serum concentration of protein S may also decrease after an infectious event - post-infectious purpura fulminans. This case illustrates that purpura fulminans due to autoantibodies against protein S, although rare, should be considered, especially in the absence of a severe acute infection. It also illustrates how in a given patient different independent factors can act simultaneously, triggering potentially devastating clinical scenarios. \u0000 \u0000 \u0000","PeriodicalId":238976,"journal":{"name":"Journal of the Portuguese Society of Dermatology and Venereology","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114173225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Two Novel ATP2C1 Mutations in Portuguese Patients with Hailey-Hailey Disease 葡萄牙黑利-黑利病患者的两种新的ATP2C1突变

Journal of the Portuguese Society of Dermatology and Venereology Pub Date : 2021-12-27 DOI: 10.29021/spdv.79.4.1409

S. Antunes-Duarte, M. Mendonça-Sanches, R. Pimenta, A. Coutinho, C. Silveira, L. Soares-de-Almeida, P. Filipe

引用次数: 0