Topical Photodynamic Therapy as a Treatment Option for Periocular Bowen's Disease: A Case Report

J. Reis, A. Machado, A. Coelho, V. Costa, M. Selores
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Abstract

Cutaneous squamous cell carcinoma in situ of the eyelid and periorbital skin malignancies is common and its management is demanding. Surgical excision is considered the first-line treatment, but these techniques have limitations. Topical photodynamic therapy is currently approved for the treatment of squamous cell carcinoma in situ in other areas, but the reports of its use in this sensitive anatomic location area are scarce. Herein we report the case of a 61-year-old-man with extensive periocular Bowen disease that was treated successfully with photodynamic therapy. Photodynamic therapy may be an option as neoadjuvant or curative therapy in selected cases, especially in sensitive anatomic locations where surgery might lead to distortion of the structures or where techniques as micrographically controlled surgery are not available.
局部光动力疗法作为眼周鲍文病的一种治疗选择:1例报告
皮肤鳞状细胞癌在眼睑和眼眶周围皮肤恶性肿瘤是常见的,其治疗要求高。手术切除被认为是一线治疗方法,但这些技术有局限性。局部光动力疗法目前被批准用于治疗其他部位的原位鳞状细胞癌,但在这个敏感的解剖位置区域使用它的报道很少。在此,我们报告一例61岁男性广泛眼周Bowen病,成功地治疗光动力疗法。在某些情况下,光动力治疗可以作为新辅助或治疗性治疗的一种选择,特别是在手术可能导致结构扭曲的敏感解剖部位或无法获得显微控制手术技术的情况下。
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